Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_single_gel_8d.class.cls #double_gel_8d_versus_single_gel_8d_repos |
| Phenotype | class.cls#double_gel_8d_versus_single_gel_8d_repos |
| Upregulated in class | double_gel_8d |
| GeneSet | ISOMERASE_ACTIVITY |
| Enrichment Score (ES) | 0.68317974 |
| Normalized Enrichment Score (NES) | 1.8818814 |
| Nominal p-value | 0.0021413276 |
| FDR q-value | 0.0064390507 |
| FWER p-Value | 0.54 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | IDI1 | IDI1 Entrez, Source | isopentenyl-diphosphate delta isomerase 1 | 110 | 0.603 | 0.1598 | Yes |
| 2 | LSS | LSS Entrez, Source | lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase) | 126 | 0.572 | 0.3182 | Yes |
| 3 | HSD3B1 | HSD3B1 Entrez, Source | hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 | 293 | 0.402 | 0.4177 | Yes |
| 4 | EBP | EBP Entrez, Source | emopamil binding protein (sterol isomerase) | 324 | 0.381 | 0.5218 | Yes |
| 5 | DDT | DDT Entrez, Source | D-dopachrome tautomerase | 583 | 0.271 | 0.5781 | Yes |
| 6 | PDIA5 | PDIA5 Entrez, Source | protein disulfide isomerase family A, member 5 | 864 | 0.212 | 0.6161 | Yes |
| 7 | PTGIS | PTGIS Entrez, Source | prostaglandin I2 (prostacyclin) synthase | 894 | 0.208 | 0.6720 | Yes |
| 8 | PGM1 | PGM1 Entrez, Source | phosphoglucomutase 1 | 1344 | 0.161 | 0.6832 | Yes |
| 9 | ERP29 | ERP29 Entrez, Source | endoplasmic reticulum protein 29 | 2404 | 0.107 | 0.6334 | No |
| 10 | TPI1 | TPI1 Entrez, Source | triosephosphate isomerase 1 | 3163 | 0.080 | 0.5987 | No |
| 11 | P4HB | P4HB Entrez, Source | procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), beta polypeptide | 4100 | 0.057 | 0.5444 | No |
| 12 | TXNDC4 | TXNDC4 Entrez, Source | thioredoxin domain containing 4 (endoplasmic reticulum) | 4337 | 0.052 | 0.5411 | No |
| 13 | PGAM2 | PGAM2 Entrez, Source | phosphoglycerate mutase 2 (muscle) | 5008 | 0.038 | 0.5014 | No |
| 14 | PDIA6 | PDIA6 Entrez, Source | protein disulfide isomerase family A, member 6 | 5150 | 0.035 | 0.5005 | No |
| 15 | PTGDS | PTGDS Entrez, Source | prostaglandin D2 synthase 21kDa (brain) | 5784 | 0.022 | 0.4592 | No |
| 16 | GNE | GNE Entrez, Source | glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase | 6397 | 0.010 | 0.4160 | No |
| 17 | TOP2A | TOP2A Entrez, Source | topoisomerase (DNA) II alpha 170kDa | 6709 | 0.004 | 0.3937 | No |
| 18 | TOP1 | TOP1 Entrez, Source | topoisomerase (DNA) I | 6869 | 0.001 | 0.3820 | No |
| 19 | PPIE | PPIE Entrez, Source | peptidylprolyl isomerase E (cyclophilin E) | 8647 | -0.038 | 0.2591 | No |
| 20 | BPGM | BPGM Entrez, Source | 2,3-bisphosphoglycerate mutase | 9399 | -0.057 | 0.2187 | No |
| 21 | PDIA3 | PDIA3 Entrez, Source | protein disulfide isomerase family A, member 3 | 11217 | -0.122 | 0.1164 | No |
| 22 | PMM1 | PMM1 Entrez, Source | phosphomannomutase 1 | 11772 | -0.155 | 0.1179 | No |
