Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_single_gel_8d.class.cls #double_gel_8d_versus_single_gel_8d_repos |
| Phenotype | class.cls#double_gel_8d_versus_single_gel_8d_repos |
| Upregulated in class | single_gel_8d |
| GeneSet | JECHLINGER_EMT_DN |
| Enrichment Score (ES) | -0.56076205 |
| Normalized Enrichment Score (NES) | -1.6102215 |
| Nominal p-value | 0.016885553 |
| FDR q-value | 0.11327356 |
| FWER p-Value | 1.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | EGR2 | EGR2 Entrez, Source | early growth response 2 (Krox-20 homolog, Drosophila) | 402 | 0.338 | 0.0227 | No |
| 2 | EGR1 | EGR1 Entrez, Source | early growth response 1 | 795 | 0.221 | 0.0279 | No |
| 3 | ITPR1 | ITPR1 Entrez, Source | inositol 1,4,5-triphosphate receptor, type 1 | 1073 | 0.185 | 0.0360 | No |
| 4 | ATF3 | ATF3 Entrez, Source | activating transcription factor 3 | 1414 | 0.156 | 0.0349 | No |
| 5 | AMD1 | AMD1 Entrez, Source | adenosylmethionine decarboxylase 1 | 1608 | 0.143 | 0.0427 | No |
| 6 | FBP2 | FBP2 Entrez, Source | fructose-1,6-bisphosphatase 2 | 2767 | 0.093 | -0.0297 | No |
| 7 | DUSP1 | DUSP1 Entrez, Source | dual specificity phosphatase 1 | 3275 | 0.077 | -0.0558 | No |
| 8 | ITGB5 | ITGB5 Entrez, Source | integrin, beta 5 | 3998 | 0.059 | -0.1007 | No |
| 9 | CDH1 | CDH1 Entrez, Source | cadherin 1, type 1, E-cadherin (epithelial) | 5558 | 0.026 | -0.2137 | No |
| 10 | PADI2 | PADI2 Entrez, Source | peptidyl arginine deiminase, type II | 5803 | 0.022 | -0.2286 | No |
| 11 | ARHGEF1 | ARHGEF1 Entrez, Source | Rho guanine nucleotide exchange factor (GEF) 1 | 7096 | -0.004 | -0.3250 | No |
| 12 | VAMP8 | VAMP8 Entrez, Source | vesicle-associated membrane protein 8 (endobrevin) | 7601 | -0.014 | -0.3606 | No |
| 13 | TGM2 | TGM2 Entrez, Source | transglutaminase 2 (C polypeptide, protein-glutamine-gamma-glutamyltransferase) | 7842 | -0.020 | -0.3756 | No |
| 14 | STAT5A | STAT5A Entrez, Source | signal transducer and activator of transcription 5A | 8184 | -0.027 | -0.3970 | No |
| 15 | TIAM1 | TIAM1 Entrez, Source | T-cell lymphoma invasion and metastasis 1 | 8679 | -0.039 | -0.4280 | No |
| 16 | ATP1A1 | ATP1A1 Entrez, Source | ATPase, Na+/K+ transporting, alpha 1 polypeptide | 9325 | -0.055 | -0.4679 | No |
| 17 | RARA | RARA Entrez, Source | retinoic acid receptor, alpha | 9483 | -0.059 | -0.4704 | No |
| 18 | TACSTD1 | TACSTD1 Entrez, Source | tumor-associated calcium signal transducer 1 | 9570 | -0.062 | -0.4672 | No |
| 19 | GRB7 | GRB7 Entrez, Source | growth factor receptor-bound protein 7 | 10441 | -0.090 | -0.5185 | No |
| 20 | SERPINB5 | SERPINB5 Entrez, Source | serpin peptidase inhibitor, clade B (ovalbumin), member 5 | 10823 | -0.104 | -0.5308 | No |
| 21 | TIMP3 | TIMP3 Entrez, Source | TIMP metallopeptidase inhibitor 3 (Sorsby fundus dystrophy, pseudoinflammatory) | 11212 | -0.122 | -0.5408 | Yes |
| 22 | CTGF | CTGF Entrez, Source | connective tissue growth factor | 11278 | -0.125 | -0.5261 | Yes |
| 23 | NUMB | NUMB Entrez, Source | numb homolog (Drosophila) | 11741 | -0.151 | -0.5370 | Yes |
| 24 | CTSH | CTSH Entrez, Source | cathepsin H | 11951 | -0.169 | -0.5263 | Yes |
| 25 | ACTN4 | ACTN4 Entrez, Source | actinin, alpha 4 | 12269 | -0.201 | -0.5186 | Yes |
| 26 | JUP | JUP Entrez, Source | junction plakoglobin | 12351 | -0.210 | -0.4918 | Yes |
| 27 | HMMR | HMMR Entrez, Source | hyaluronan-mediated motility receptor (RHAMM) | 12560 | -0.237 | -0.4703 | Yes |
| 28 | MYH9 | MYH9 Entrez, Source | myosin, heavy chain 9, non-muscle | 12585 | -0.241 | -0.4342 | Yes |
| 29 | SGK | SGK Entrez, Source | serum/glucocorticoid regulated kinase | 12997 | -0.362 | -0.4084 | Yes |
| 30 | TGFB3 | TGFB3 Entrez, Source | transforming growth factor, beta 3 | 13277 | -0.783 | -0.3066 | Yes |
| 31 | KITLG | KITLG Entrez, Source | KIT ligand | 13294 | -0.868 | -0.1717 | Yes |
| 32 | F3 | F3 Entrez, Source | coagulation factor III (thromboplastin, tissue factor) | 13324 | -1.119 | 0.0014 | Yes |
