Datasetdouble_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls
#double_gel_8d_versus_single_gel_8d.class.cls
#double_gel_8d_versus_single_gel_8d_repos
Phenotypeclass.cls#double_gel_8d_versus_single_gel_8d_repos
Upregulated in classsingle_gel_8d
GeneSetJISON_SICKLECELL_DIFF
Enrichment Score (ES)-0.4171115
Normalized Enrichment Score (NES)-1.6541272
Nominal p-value0.0
FDR q-value0.09607506
FWER p-Value1.0
Table: GSEA Results Summary



Fig 1: Enrichment plot: JISON_SICKLECELL_DIFF   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

PROBEGENE SYMBOLGENE_TITLERANK IN GENE LISTRANK METRIC SCORERUNNING ESCORE ENRICHMENT
1LEPRLEPR
Entrez,  Source
leptin receptor850.6390.0169No
2SQLESQLE
Entrez,  Source
squalene epoxidase1880.4850.0269No
3CD9CD9
Entrez,  Source
CD9 molecule5120.2950.0131No
4KYNUKYNU
Entrez,  Source
kynureninase (L-kynurenine hydrolase)5480.2830.0208No
5IFIT2IFIT2
Entrez,  Source
interferon-induced protein with tetratricopeptide repeats 26090.2640.0259No
6ATOX1ATOX1
Entrez,  Source
ATX1 antioxidant protein 1 homolog (yeast)6530.2510.0318No
7ATP6V0A1ATP6V0A1
Entrez,  Source
ATPase, H+ transporting, lysosomal V0 subunit a18690.2120.0231No
8CLIC2CLIC2
Entrez,  Source
chloride intracellular channel 29350.2020.0256No
9P2RX4P2RX4
Entrez,  Source
purinergic receptor P2X, ligand-gated ion channel, 49380.2010.0328No
10NFE2NFE2
Entrez,  Source
nuclear factor (erythroid-derived 2), 45kDa10710.1850.0295No
11NELL2NELL2
Entrez,  Source
NEL-like 2 (chicken)11380.1780.0310No
12SLC22A4SLC22A4
Entrez,  Source
solute carrier family 22 (organic cation transporter), member 411950.1710.0330No
13MCF2LMCF2L
Entrez,  Source
MCF.2 cell line derived transforming sequence-like12150.1690.0377No
14NAB1NAB1
Entrez,  Source
NGFI-A binding protein 1 (EGR1 binding protein 1)12450.1670.0416No
15POLGPOLG
Entrez,  Source
polymerase (DNA directed), gamma12880.1650.0445No
16IFIT3IFIT3
Entrez,  Source
interferon-induced protein with tetratricopeptide repeats 314070.1560.0412No
17SELPSELP
Entrez,  Source
selectin P (granule membrane protein 140kDa, antigen CD62)14080.1560.0469No
18ATF3ATF3
Entrez,  Source
activating transcription factor 314140.1560.0522No
19FYNFYN
Entrez,  Source
FYN oncogene related to SRC, FGR, YES16910.1370.0362No
20UBE2L6UBE2L6
Entrez,  Source
ubiquitin-conjugating enzyme E2L 617890.1320.0337No
21BST2BST2
Entrez,  Source
bone marrow stromal cell antigen 218110.1300.0368No
22COX17COX17
Entrez,  Source
COX17 cytochrome c oxidase assembly homolog (S. cerevisiae)19210.1250.0331No
23IFI30IFI30
Entrez,  Source
interferon, gamma-inducible protein 3023790.1070.0023No
24TALDO1TALDO1
Entrez,  Source
transaldolase 124430.1050.0013No
25IGF2BP3IGF2BP3
Entrez,  Source
insulin-like growth factor 2 mRNA binding protein 325300.102-0.0015No
26ST3GAL5ST3GAL5
Entrez,  Source
ST3 beta-galactoside alpha-2,3-sialyltransferase 526160.099-0.0044No
27RUNX3RUNX3
Entrez,  Source
runt-related transcription factor 327070.095-0.0078No
28TRAF3IP3TRAF3IP3
Entrez,  Source
TRAF3 interacting protein 327210.095-0.0053No
29HBBHBB
Entrez,  Source
hemoglobin, beta28260.091-0.0099No
30NDUFS2NDUFS2
Entrez,  Source
NADH dehydrogenase (ubiquinone) Fe-S protein 2, 49kDa (NADH-coenzyme Q reductase)29260.087-0.0142No
31MMP3MMP3
Entrez,  Source
matrix metallopeptidase 3 (stromelysin 1, progelatinase)29810.085-0.0152No
32UNGUNG
Entrez,  Source
uracil-DNA glycosylase31940.079-0.0285No
33CPLX2CPLX2
Entrez,  Source
complexin 232510.077-0.0299No
34FGF9FGF9
Entrez,  Source
fibroblast growth factor 9 (glia-activating factor)32790.077-0.0292No
35F13A1F13A1
Entrez,  Source
coagulation factor XIII, A1 polypeptide33040.076-0.0282No
36TMEM66TMEM66
Entrez,  Source
transmembrane protein 6633270.075-0.0272No
37NOTCH3NOTCH3
Entrez,  Source
Notch homolog 3 (Drosophila)33390.075-0.0253No
38SERPING1SERPING1
Entrez,  Source
serpin peptidase inhibitor, clade G (C1 inhibitor), member 1, (angioedema, hereditary)33780.074-0.0254No
39PTPROPTPRO
Entrez,  Source
protein tyrosine phosphatase, receptor type, O34570.072-0.0287No
40PTPRMPTPRM
Entrez,  Source
protein tyrosine phosphatase, receptor type, M36190.068-0.0385No
41MSMBMSMB
Entrez,  Source
microseminoprotein, beta-37640.065-0.0471No
42PDE3BPDE3B
Entrez,  Source
phosphodiesterase 3B, cGMP-inhibited37730.065-0.0453No
43DUSP2DUSP2
Entrez,  Source
dual specificity phosphatase 238020.064-0.0451No
44RNF126RNF126
Entrez,  Source
ring finger protein 12639380.061-0.0532No
45ITGB5ITGB5
Entrez,  Source
integrin, beta 539980.059-0.0555No
46BNIP3LBNIP3L
Entrez,  Source
BCL2/adenovirus E1B 19kDa interacting protein 3-like40110.059-0.0543No
47NGFRNGFR
Entrez,  Source
nerve growth factor receptor (TNFR superfamily, member 16)40170.059-0.0525No
48P4HBP4HB
Entrez,  Source
procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), beta polypeptide41000.057-0.0566No
49BTG1BTG1
Entrez,  Source
B-cell translocation gene 1, anti-proliferative43540.052-0.0740No
50COX6CCOX6C
Entrez,  Source
cytochrome c oxidase subunit VIc44410.050-0.0787No
51STAT1STAT1
Entrez,  Source
signal transducer and activator of transcription 1, 91kDa48190.041-0.1059No
52IFIT1IFIT1
Entrez,  Source
interferon-induced protein with tetratricopeptide repeats 149400.039-0.1136No
53BLVRABLVRA
Entrez,  Source
biliverdin reductase A49730.038-0.1147No
54CEBPECEBPE
Entrez,  Source
CCAAT/enhancer binding protein (C/EBP), epsilon49770.038-0.1135No
55KLRK1KLRK1
Entrez,  Source
killer cell lectin-like receptor subfamily K, member 149980.038-0.1136No
56CXCL10CXCL10
Entrez,  Source
chemokine (C-X-C motif) ligand 1051280.035-0.1222No
57CXCR4CXCR4
Entrez,  Source
chemokine (C-X-C motif) receptor 452040.034-0.1266No
58PNMTPNMT
Entrez,  Source
phenylethanolamine N-methyltransferase52360.033-0.1278No
59TCTATCTA
Entrez,  Source
T-cell leukemia translocation altered gene54500.029-0.1429No
60SLC36A1SLC36A1
Entrez,  Source
solute carrier family 36 (proton/amino acid symporter), member 155940.026-0.1529No
61SFRS2SFRS2
Entrez,  Source
splicing factor, arginine/serine-rich 255970.026-0.1521No
62LYL1LYL1
Entrez,  Source
lymphoblastic leukemia derived sequence 156240.025-0.1532No
63RBL2RBL2
Entrez,  Source
retinoblastoma-like 2 (p130)61250.016-0.1907No
64ELA2ELA2
Entrez,  Source
elastase 2, neutrophil63850.010-0.2100No
65MX1MX1
Entrez,  Source
myxovirus (influenza virus) resistance 1, interferon-inducible protein p78 (mouse)64040.009-0.2111No
66PSMB2PSMB2
Entrez,  Source
proteasome (prosome, macropain) subunit, beta type, 265240.007-0.2199No
67HNRPDLHNRPDL
Entrez,  Source
heterogeneous nuclear ribonucleoprotein D-like65560.007-0.2220No
68CALRCALR
Entrez,  Source
calreticulin65580.007-0.2218No
69SLC4A7SLC4A7
Entrez,  Source
solute carrier family 4, sodium bicarbonate cotransporter, member 766660.005-0.2298No
70SLC2A3SLC2A3
Entrez,  Source
solute carrier family 2 (facilitated glucose transporter), member 366830.004-0.2308No
71PFN2PFN2
Entrez,  Source
profilin 267450.003-0.2354No
72IL5RAIL5RA
Entrez,  Source
interleukin 5 receptor, alpha67790.003-0.2378No
73PLEKPLEK
Entrez,  Source
pleckstrin68340.002-0.2418No
74WSB2WSB2
Entrez,  Source
WD repeat and SOCS box-containing 268370.002-0.2419No
75ANP32BANP32B
Entrez,  Source
acidic (leucine-rich) nuclear phosphoprotein 32 family, member B68790.001-0.2450No
76NAP1L1NAP1L1
Entrez,  Source
nucleosome assembly protein 1-like 16915-0.000-0.2477No
77NEK4NEK4
Entrez,  Source
NIMA (never in mitosis gene a)-related kinase 46956-0.001-0.2507No
78SFRS5SFRS5
Entrez,  Source
splicing factor, arginine/serine-rich 57071-0.004-0.2592No
79RPL41RPL41
Entrez,  Source
ribosomal protein L417088-0.004-0.2603No
80IMPDH2IMPDH2
Entrez,  Source
IMP (inosine monophosphate) dehydrogenase 27268-0.008-0.2737No
81PABPC4PABPC4
Entrez,  Source
poly(A) binding protein, cytoplasmic 4 (inducible form)7324-0.009-0.2775No
82RPL37RPL37
Entrez,  Source
ribosomal protein L377466-0.012-0.2878No
83VPS52VPS52
Entrez,  Source
vacuolar protein sorting 52 (S. cerevisiae)7507-0.013-0.2904No
84GNG5GNG5
Entrez,  Source
guanine nucleotide binding protein (G protein), gamma 57559-0.014-0.2938No
85VAMP8VAMP8
Entrez,  Source
vesicle-associated membrane protein 8 (endobrevin)7601-0.014-0.2964No
86TMED10TMED10
Entrez,  Source
transmembrane emp24-like trafficking protein 10 (yeast)7641-0.015-0.2988No
87RBBP6RBBP6
Entrez,  Source
retinoblastoma binding protein 67722-0.017-0.3043No
88EEF2EEF2
Entrez,  Source
eukaryotic translation elongation factor 27765-0.018-0.3068No
89RPS6RPS6
Entrez,  Source
ribosomal protein S67800-0.019-0.3087No
90LAMP2LAMP2
Entrez,  Source
lysosomal-associated membrane protein 27865-0.020-0.3129No
91EEF1A1EEF1A1
Entrez,  Source
eukaryotic translation elongation factor 1 alpha 17913-0.021-0.3157No
92NUCB1NUCB1
Entrez,  Source
nucleobindin 17926-0.022-0.3158No
93RPLP1RPLP1
Entrez,  Source
ribosomal protein, large, P18028-0.024-0.3226No
94RHEBRHEB
Entrez,  Source
Ras homolog enriched in brain8044-0.024-0.3229No
95RPL4RPL4
Entrez,  Source
ribosomal protein L48146-0.026-0.3296No
96TFECTFEC
Entrez,  Source
transcription factor EC8147-0.026-0.3286No
97NPM1NPM1
Entrez,  Source
nucleophosmin (nucleolar phosphoprotein B23, numatrin)8204-0.028-0.3319No
98TIMM17ATIMM17A
Entrez,  Source
translocase of inner mitochondrial membrane 17 homolog A (yeast)8212-0.028-0.3314No
99RPS24RPS24
Entrez,  Source
ribosomal protein S248294-0.030-0.3365No
100RPL9RPL9
Entrez,  Source
ribosomal protein L98332-0.031-0.3382No
101RPL24RPL24
Entrez,  Source
ribosomal protein L248338-0.031-0.3374No
102OTUD4OTUD4
Entrez,  Source
OTU domain containing 48435-0.033-0.3435No
103CTSLCTSL
Entrez,  Source
cathepsin L8440-0.033-0.3426No
104ESR1ESR1
Entrez,  Source
estrogen receptor 18446-0.033-0.3418No
105RPL5RPL5
Entrez,  Source
ribosomal protein L58527-0.035-0.3466No
106RPS13RPS13
Entrez,  Source
ribosomal protein S138611-0.037-0.3516No
107RPL17RPL17
Entrez,  Source
ribosomal protein L178625-0.037-0.3512No
108TDRD7TDRD7
Entrez,  Source
tudor domain containing 78695-0.039-0.3550No
109CELSR3CELSR3
Entrez,  Source
cadherin, EGF LAG seven-pass G-type receptor 3 (flamingo homolog, Drosophila)8696-0.039-0.3536No
110RPL7RPL7
Entrez,  Source
ribosomal protein L78850-0.042-0.3637No
111RPL30RPL30
Entrez,  Source
ribosomal protein L308866-0.043-0.3633No
112RPS27ARPS27A
Entrez,  Source
ribosomal protein S27a8887-0.043-0.3632No
113CASP7CASP7
Entrez,  Source
caspase 7, apoptosis-related cysteine peptidase8912-0.044-0.3634No
114RPL19RPL19
Entrez,  Source
ribosomal protein L199063-0.048-0.3731No
115GADD45AGADD45A
Entrez,  Source
growth arrest and DNA-damage-inducible, alpha9083-0.048-0.3728No
116ITGADITGAD
Entrez,  Source
integrin, alpha D9118-0.049-0.3736No
117CDS2CDS2
Entrez,  Source
CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 29174-0.051-0.3759No
118RPL13RPL13
Entrez,  Source
ribosomal protein L139201-0.051-0.3760No
119PSME2PSME2
Entrez,  Source
proteasome (prosome, macropain) activator subunit 2 (PA28 beta)9205-0.051-0.3744No
120RPL6RPL6
Entrez,  Source
ribosomal protein L69278-0.054-0.3779No
121RPL10ARPL10A
Entrez,  Source
ribosomal protein L10a9348-0.056-0.3811No
122EIF3S6EIF3S6
Entrez,  Source
eukaryotic translation initiation factor 3, subunit 6 48kDa9359-0.056-0.3798No
123EIF3S3EIF3S3
Entrez,  Source
eukaryotic translation initiation factor 3, subunit 3 gamma, 40kDa9396-0.057-0.3805No
124OAZ1OAZ1
Entrez,  Source
ornithine decarboxylase antizyme 19397-0.057-0.3784No
125STX7STX7
Entrez,  Source
syntaxin 79420-0.058-0.3780No
126RPL14RPL14
Entrez,  Source
ribosomal protein L149445-0.058-0.3777No
127BTF3BTF3
Entrez,  Source
basic transcription factor 39484-0.059-0.3784No
128EIF3S7EIF3S7
Entrez,  Source
eukaryotic translation initiation factor 3, subunit 7 zeta, 66/67kDa9487-0.059-0.3764No
129RPL22RPL22
Entrez,  Source
ribosomal protein L229500-0.060-0.3751No
130ARHGEF7ARHGEF7
Entrez,  Source
Rho guanine nucleotide exchange factor (GEF) 79623-0.063-0.3821No
131GNG11GNG11
Entrez,  Source
guanine nucleotide binding protein (G protein), gamma 119666-0.064-0.3829No
132GTF2BGTF2B
Entrez,  Source
general transcription factor IIB9753-0.067-0.3870No
133YWHAHYWHAH
Entrez,  Source
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide9794-0.068-0.3876No
134AESAES
Entrez,  Source
amino-terminal enhancer of split9813-0.069-0.3865No
135FN1FN1
Entrez,  Source
fibronectin 19917-0.072-0.3917No
136DDX5DDX5
Entrez,  Source
DEAD (Asp-Glu-Ala-Asp) box polypeptide 59920-0.072-0.3892No
137GSTO1GSTO1
Entrez,  Source
glutathione S-transferase omega 110091-0.078-0.3993No
138ID1ID1
Entrez,  Source
inhibitor of DNA binding 1, dominant negative helix-loop-helix protein10098-0.078-0.3969No
139RPL11RPL11
Entrez,  Source
ribosomal protein L1110109-0.079-0.3947No
140ERCC3ERCC3
Entrez,  Source
excision repair cross-complementing rodent repair deficiency, complementation group 3 (xeroderma pigmentosum group B complementing)10127-0.079-0.3931No
141KLF9KLF9
Entrez,  Source
Kruppel-like factor 910129-0.079-0.3903No
142FBLFBL
Entrez,  Source
fibrillarin10172-0.080-0.3906No
143EIF4BEIF4B
Entrez,  Source
eukaryotic translation initiation factor 4B10193-0.081-0.3891No
144HSPA8HSPA8
Entrez,  Source
heat shock 70kDa protein 810327-0.086-0.3961No
145EEF1GEEF1G
Entrez,  Source
eukaryotic translation elongation factor 1 gamma10329-0.086-0.3931No
146EIF4A1EIF4A1
Entrez,  Source
eukaryotic translation initiation factor 4A, isoform 110424-0.089-0.3970No
147PPP2CBPPP2CB
Entrez,  Source
protein phosphatase 2 (formerly 2A), catalytic subunit, beta isoform10468-0.091-0.3969No
148CSNK1ECSNK1E
Entrez,  Source
casein kinase 1, epsilon10537-0.093-0.3987No
149ATP6V1DATP6V1D
Entrez,  Source
ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D10581-0.095-0.3985No
150ITPKBITPKB
Entrez,  Source
inositol 1,4,5-trisphosphate 3-kinase B10615-0.096-0.3976No
151CDX2CDX2
Entrez,  Source
caudal type homeobox transcription factor 210635-0.096-0.3955No
152PRDX1PRDX1
Entrez,  Source
peroxiredoxin 110681-0.098-0.3953No
153EIF4G2EIF4G2
Entrez,  Source
eukaryotic translation initiation factor 4 gamma, 210707-0.099-0.3936No
154AKR1A1AKR1A1
Entrez,  Source
aldo-keto reductase family 1, member A1 (aldehyde reductase)10743-0.100-0.3926No
155TMED1TMED1
Entrez,  Source
transmembrane emp24 protein transport domain containing 110860-0.105-0.3976No
156RNF44RNF44
Entrez,  Source
ring finger protein 4410881-0.106-0.3953No
157EMP3EMP3
Entrez,  Source
epithelial membrane protein 310906-0.107-0.3932No
158HNRPH1HNRPH1
Entrez,  Source
heterogeneous nuclear ribonucleoprotein H1 (H)10957-0.109-0.3930No
159H1F0H1F0
Entrez,  Source
H1 histone family, member 011275-0.125-0.4125Yes
160SFPQSFPQ
Entrez,  Source
splicing factor proline/glutamine-rich (polypyrimidine tract binding protein associated)11277-0.125-0.4080Yes
161TRIM32TRIM32
Entrez,  Source
tripartite motif-containing 3211322-0.127-0.4067Yes
162LMNB1LMNB1
Entrez,  Source
lamin B111329-0.128-0.4025Yes
163HMOX1HMOX1
Entrez,  Source
heme oxygenase (decycling) 111363-0.129-0.4003Yes
164ITPR3ITPR3
Entrez,  Source
inositol 1,4,5-triphosphate receptor, type 311479-0.136-0.4041Yes
165ATP1B1ATP1B1
Entrez,  Source
ATPase, Na+/K+ transporting, beta 1 polypeptide11599-0.144-0.4079Yes
166GPX1GPX1
Entrez,  Source
glutathione peroxidase 111620-0.145-0.4041Yes
167EIF4A2EIF4A2
Entrez,  Source
eukaryotic translation initiation factor 4A, isoform 211679-0.148-0.4031Yes
168GM2AGM2A
Entrez,  Source
GM2 ganglioside activator11694-0.149-0.3987Yes
169PRDX4PRDX4
Entrez,  Source
peroxiredoxin 411707-0.150-0.3941Yes
170BCLAF1BCLAF1
Entrez,  Source
BCL2-associated transcription factor 111717-0.150-0.3893Yes
171PMM1PMM1
Entrez,  Source
phosphomannomutase 111772-0.155-0.3878Yes
172ASCC3L1ASCC3L1
Entrez,  Source
activating signal cointegrator 1 complex subunit 3-like 111781-0.155-0.3827Yes
173GADD45BGADD45B
Entrez,  Source
growth arrest and DNA-damage-inducible, beta11783-0.155-0.3771Yes
174PSMB8PSMB8
Entrez,  Source
proteasome (prosome, macropain) subunit, beta type, 8 (large multifunctional peptidase 7)11784-0.155-0.3714Yes
175PSMB9PSMB9
Entrez,  Source
proteasome (prosome, macropain) subunit, beta type, 9 (large multifunctional peptidase 2)11832-0.159-0.3692Yes
176JAK1JAK1
Entrez,  Source
Janus kinase 1 (a protein tyrosine kinase)11891-0.164-0.3676Yes
177TXNRD1TXNRD1
Entrez,  Source
thioredoxin reductase 111903-0.166-0.3624Yes
178TCN2TCN2
Entrez,  Source
transcobalamin II; macrocytic anemia11922-0.167-0.3576Yes
179RAB13RAB13
Entrez,  Source
RAB13, member RAS oncogene family11994-0.172-0.3567Yes
180CDKN1ACDKN1A
Entrez,  Source
cyclin-dependent kinase inhibitor 1A (p21, Cip1)12163-0.188-0.3627Yes
181TAP1TAP1
Entrez,  Source
transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)12194-0.191-0.3580Yes
182IL15IL15
Entrez,  Source
interleukin 1512233-0.197-0.3536Yes
183VAMP5VAMP5
Entrez,  Source
vesicle-associated membrane protein 5 (myobrevin)12345-0.209-0.3545Yes
184OGTOGT
Entrez,  Source
O-linked N-acetylglucosamine (GlcNAc) transferase (UDP-N-acetylglucosamine:polypeptide-N-acetylglucosaminyl transferase)12392-0.214-0.3501Yes
185MSH2MSH2
Entrez,  Source
mutS homolog 2, colon cancer, nonpolyposis type 1 (E. coli)12401-0.215-0.3429Yes
186PTK2PTK2
Entrez,  Source
PTK2 protein tyrosine kinase 212413-0.216-0.3358Yes
187PPGBPPGB
Entrez,  Source
protective protein for beta-galactosidase (galactosialidosis)12547-0.235-0.3373Yes
188RENBPRENBP
Entrez,  Source
renin binding protein12639-0.251-0.3351Yes
189SATB1SATB1
Entrez,  Source
special AT-rich sequence binding protein 1 (binds to nuclear matrix/scaffold-associating DNA's)12659-0.255-0.3272Yes
190CD151CD151
Entrez,  Source
CD151 molecule (Raph blood group)12718-0.268-0.3218Yes
191CLIC4CLIC4
Entrez,  Source
chloride intracellular channel 412732-0.272-0.3128Yes
192ANXA3ANXA3
Entrez,  Source
annexin A312750-0.275-0.3041Yes
193ADMADM
Entrez,  Source
adrenomedullin12796-0.285-0.2971Yes
194IFI44IFI44
Entrez,  Source
interferon-induced protein 4412827-0.295-0.2886Yes
195IFI35IFI35
Entrez,  Source
interferon-induced protein 3512894-0.318-0.2820Yes
196SNNSNN
Entrez,  Source
stannin12996-0.362-0.2764Yes
197TPM1TPM1
Entrez,  Source
tropomyosin 1 (alpha)12998-0.364-0.2632Yes
198TXNIPTXNIP
Entrez,  Source
thioredoxin interacting protein13022-0.377-0.2511Yes
199DGKADGKA
Entrez,  Source
diacylglycerol kinase, alpha 80kDa13029-0.381-0.2377Yes
200CLIC1CLIC1
Entrez,  Source
chloride intracellular channel 113030-0.381-0.2237Yes
201FNBP4FNBP4
Entrez,  Source
formin binding protein 413036-0.385-0.2100Yes
202NNATNNAT
Entrez,  Source
neuronatin13037-0.385-0.1959Yes
203TGFB1TGFB1
Entrez,  Source
transforming growth factor, beta 1 (Camurati-Engelmann disease)13047-0.395-0.1822Yes
204CIRBPCIRBP
Entrez,  Source
cold inducible RNA binding protein13049-0.397-0.1677Yes
205JAK2JAK2
Entrez,  Source
Janus kinase 2 (a protein tyrosine kinase)13065-0.406-0.1540Yes
206TSC22D3TSC22D3
Entrez,  Source
TSC22 domain family, member 313117-0.441-0.1418Yes
207GLSGLS
Entrez,  Source
glutaminase13118-0.442-0.1256Yes
208PTMAPTMA
Entrez,  Source
prothymosin, alpha (gene sequence 28)13120-0.443-0.1095Yes
209GPX3GPX3
Entrez,  Source
glutathione peroxidase 3 (plasma)13136-0.457-0.0939Yes
210TIMP1TIMP1
Entrez,  Source
TIMP metallopeptidase inhibitor 113213-0.582-0.0784Yes
211DOK1DOK1
Entrez,  Source
docking protein 1, 62kDa (downstream of tyrosine kinase 1)13216-0.591-0.0569Yes
212AXLAXL
Entrez,  Source
AXL receptor tyrosine kinase13219-0.601-0.0351Yes
213GBP2GBP2
Entrez,  Source
guanylate binding protein 2, interferon-inducible13329-1.2140.0010Yes
Table: GSEA details [plain text format]



Fig 2: JISON_SICKLECELL_DIFF   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet



Fig 3: JISON_SICKLECELL_DIFF: Random ES distribution   
Gene set null distribution of ES for JISON_SICKLECELL_DIFF