Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_single_gel_8d.class.cls #double_gel_8d_versus_single_gel_8d_repos |
| Phenotype | class.cls#double_gel_8d_versus_single_gel_8d_repos |
| Upregulated in class | single_gel_8d |
| GeneSet | JISON_SICKLE_CELL |
| Enrichment Score (ES) | -0.6454777 |
| Normalized Enrichment Score (NES) | -1.7476163 |
| Nominal p-value | 0.0037313432 |
| FDR q-value | 0.062963516 |
| FWER p-Value | 0.994 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | ATOX1 | ATOX1 Entrez, Source | ATX1 antioxidant protein 1 homolog (yeast) | 653 | 0.251 | 0.0152 | No |
| 2 | SELP | SELP Entrez, Source | selectin P (granule membrane protein 140kDa, antigen CD62) | 1408 | 0.156 | -0.0014 | No |
| 3 | F13A1 | F13A1 Entrez, Source | coagulation factor XIII, A1 polypeptide | 3304 | 0.076 | -0.1242 | No |
| 4 | PDE3B | PDE3B Entrez, Source | phosphodiesterase 3B, cGMP-inhibited | 3773 | 0.065 | -0.1428 | No |
| 5 | BNIP3L | BNIP3L Entrez, Source | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 4011 | 0.059 | -0.1455 | No |
| 6 | STAT1 | STAT1 Entrez, Source | signal transducer and activator of transcription 1, 91kDa | 4819 | 0.041 | -0.1955 | No |
| 7 | BLVRA | BLVRA Entrez, Source | biliverdin reductase A | 4973 | 0.038 | -0.1972 | No |
| 8 | CASP7 | CASP7 Entrez, Source | caspase 7, apoptosis-related cysteine peptidase | 8912 | -0.044 | -0.4816 | No |
| 9 | GSTO1 | GSTO1 Entrez, Source | glutathione S-transferase omega 1 | 10091 | -0.078 | -0.5501 | No |
| 10 | HMOX1 | HMOX1 Entrez, Source | heme oxygenase (decycling) 1 | 11363 | -0.129 | -0.6124 | Yes |
| 11 | ITPR3 | ITPR3 Entrez, Source | inositol 1,4,5-triphosphate receptor, type 3 | 11479 | -0.136 | -0.5863 | Yes |
| 12 | GPX1 | GPX1 Entrez, Source | glutathione peroxidase 1 | 11620 | -0.145 | -0.5598 | Yes |
| 13 | PRDX4 | PRDX4 Entrez, Source | peroxiredoxin 4 | 11707 | -0.150 | -0.5279 | Yes |
| 14 | GADD45B | GADD45B Entrez, Source | growth arrest and DNA-damage-inducible, beta | 11783 | -0.155 | -0.4939 | Yes |
| 15 | JAK1 | JAK1 Entrez, Source | Janus kinase 1 (a protein tyrosine kinase) | 11891 | -0.164 | -0.4600 | Yes |
| 16 | TXNRD1 | TXNRD1 Entrez, Source | thioredoxin reductase 1 | 11903 | -0.166 | -0.4185 | Yes |
| 17 | CDKN1A | CDKN1A Entrez, Source | cyclin-dependent kinase inhibitor 1A (p21, Cip1) | 12163 | -0.188 | -0.3899 | Yes |
| 18 | IL15 | IL15 Entrez, Source | interleukin 15 | 12233 | -0.197 | -0.3447 | Yes |
| 19 | ADM | ADM Entrez, Source | adrenomedullin | 12796 | -0.285 | -0.3141 | Yes |
| 20 | DGKA | DGKA Entrez, Source | diacylglycerol kinase, alpha 80kDa | 13029 | -0.381 | -0.2342 | Yes |
| 21 | JAK2 | JAK2 Entrez, Source | Janus kinase 2 (a protein tyrosine kinase) | 13065 | -0.406 | -0.1329 | Yes |
| 22 | AXL | AXL Entrez, Source | AXL receptor tyrosine kinase | 13219 | -0.601 | 0.0092 | Yes |
