Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_single_gel_8d.class.cls #double_gel_8d_versus_single_gel_8d_repos |
| Phenotype | class.cls#double_gel_8d_versus_single_gel_8d_repos |
| Upregulated in class | double_gel_8d |
| GeneSet | LEE_ACOX1_DN |
| Enrichment Score (ES) | 0.59410596 |
| Normalized Enrichment Score (NES) | 1.9663485 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.0025581701 |
| FWER p-Value | 0.209 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | HGD | HGD Entrez, Source | homogentisate 1,2-dioxygenase (homogentisate oxidase) | 17 | 0.930 | 0.0685 | Yes |
| 2 | G6PC | G6PC Entrez, Source | glucose-6-phosphatase, catalytic subunit | 21 | 0.893 | 0.1353 | Yes |
| 3 | OTC | OTC Entrez, Source | ornithine carbamoyltransferase | 49 | 0.765 | 0.1907 | Yes |
| 4 | GOT1 | GOT1 Entrez, Source | glutamic-oxaloacetic transaminase 1, soluble (aspartate aminotransferase 1) | 56 | 0.731 | 0.2451 | Yes |
| 5 | PPP1R3C | PPP1R3C Entrez, Source | protein phosphatase 1, regulatory (inhibitor) subunit 3C | 146 | 0.543 | 0.2791 | Yes |
| 6 | MBL2 | MBL2 Entrez, Source | mannose-binding lectin (protein C) 2, soluble (opsonic defect) | 263 | 0.424 | 0.3023 | Yes |
| 7 | KHK | KHK Entrez, Source | ketohexokinase (fructokinase) | 285 | 0.407 | 0.3313 | Yes |
| 8 | PHLDA1 | PHLDA1 Entrez, Source | pleckstrin homology-like domain, family A, member 1 | 303 | 0.396 | 0.3597 | Yes |
| 9 | SLCO2B1 | SLCO2B1 Entrez, Source | solute carrier organic anion transporter family, member 2B1 | 322 | 0.383 | 0.3871 | Yes |
| 10 | TDO2 | TDO2 Entrez, Source | tryptophan 2,3-dioxygenase | 355 | 0.360 | 0.4117 | Yes |
| 11 | SLC27A5 | SLC27A5 Entrez, Source | solute carrier family 27 (fatty acid transporter), member 5 | 392 | 0.341 | 0.4346 | Yes |
| 12 | CYP4F2 | CYP4F2 Entrez, Source | cytochrome P450, family 4, subfamily F, polypeptide 2 | 403 | 0.337 | 0.4592 | Yes |
| 13 | PAH | PAH Entrez, Source | phenylalanine hydroxylase | 411 | 0.336 | 0.4839 | Yes |
| 14 | C4BPA | C4BPA Entrez, Source | complement component 4 binding protein, alpha | 417 | 0.334 | 0.5085 | Yes |
| 15 | HSD11B1 | HSD11B1 Entrez, Source | hydroxysteroid (11-beta) dehydrogenase 1 | 487 | 0.306 | 0.5263 | Yes |
| 16 | NR1H3 | NR1H3 Entrez, Source | nuclear receptor subfamily 1, group H, member 3 | 540 | 0.287 | 0.5439 | Yes |
| 17 | HAL | HAL Entrez, Source | histidine ammonia-lyase | 549 | 0.282 | 0.5645 | Yes |
| 18 | BAAT | BAAT Entrez, Source | bile acid Coenzyme A: amino acid N-acyltransferase (glycine N-choloyltransferase) | 580 | 0.273 | 0.5827 | Yes |
| 19 | SLC37A4 | SLC37A4 Entrez, Source | solute carrier family 37 (glycerol-6-phosphate transporter), member 4 | 675 | 0.246 | 0.5941 | Yes |
| 20 | IL1RAP | IL1RAP Entrez, Source | interleukin 1 receptor accessory protein | 1037 | 0.188 | 0.5811 | No |
| 21 | HPD | HPD Entrez, Source | 4-hydroxyphenylpyruvate dioxygenase | 1252 | 0.167 | 0.5775 | No |
| 22 | OAT | OAT Entrez, Source | ornithine aminotransferase (gyrate atrophy) | 1460 | 0.152 | 0.5734 | No |
| 23 | MYH1 | MYH1 Entrez, Source | myosin, heavy chain 1, skeletal muscle, adult | 1512 | 0.148 | 0.5807 | No |
| 24 | DPP4 | DPP4 Entrez, Source | dipeptidyl-peptidase 4 (CD26, adenosine deaminase complexing protein 2) | 1919 | 0.125 | 0.5596 | No |
| 25 | GSTA3 | GSTA3 Entrez, Source | glutathione S-transferase A3 | 2058 | 0.119 | 0.5581 | No |
| 26 | TNNT3 | TNNT3 Entrez, Source | troponin T type 3 (skeletal, fast) | 2118 | 0.117 | 0.5625 | No |
| 27 | ATP2A1 | ATP2A1 Entrez, Source | ATPase, Ca++ transporting, cardiac muscle, fast twitch 1 | 2970 | 0.086 | 0.5049 | No |
| 28 | SFTPD | SFTPD Entrez, Source | surfactant, pulmonary-associated protein D | 3017 | 0.084 | 0.5078 | No |
| 29 | SERPINA1 | SERPINA1 Entrez, Source | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | 4761 | 0.043 | 0.3799 | No |
| 30 | PRODH | PRODH Entrez, Source | proline dehydrogenase (oxidase) 1 | 5569 | 0.026 | 0.3212 | No |
| 31 | CYP26A1 | CYP26A1 Entrez, Source | cytochrome P450, family 26, subfamily A, polypeptide 1 | 5664 | 0.024 | 0.3159 | No |
| 32 | NINJ1 | NINJ1 Entrez, Source | ninjurin 1 | 5903 | 0.020 | 0.2996 | No |
| 33 | ELA2 | ELA2 Entrez, Source | elastase 2, neutrophil | 6385 | 0.010 | 0.2641 | No |
| 34 | CYP7B1 | CYP7B1 Entrez, Source | cytochrome P450, family 7, subfamily B, polypeptide 1 | 7432 | -0.011 | 0.1863 | No |
| 35 | CPOX | CPOX Entrez, Source | coproporphyrinogen oxidase | 8432 | -0.033 | 0.1136 | No |
| 36 | SLC29A1 | SLC29A1 Entrez, Source | solute carrier family 29 (nucleoside transporters), member 1 | 9613 | -0.063 | 0.0296 | No |
| 37 | EGFR | EGFR Entrez, Source | epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian) | 10171 | -0.080 | -0.0062 | No |
| 38 | SELENBP1 | SELENBP1 Entrez, Source | selenium binding protein 1 | 10631 | -0.096 | -0.0335 | No |
| 39 | HBP1 | HBP1 Entrez, Source | HMG-box transcription factor 1 | 10662 | -0.097 | -0.0285 | No |
| 40 | AKAP11 | AKAP11 Entrez, Source | A kinase (PRKA) anchor protein 11 | 11090 | -0.116 | -0.0519 | No |
| 41 | GPR37 | GPR37 Entrez, Source | G protein-coupled receptor 37 (endothelin receptor type B-like) | 11472 | -0.135 | -0.0704 | No |
| 42 | RNASE4 | RNASE4 Entrez, Source | ribonuclease, RNase A family, 4 | 12272 | -0.201 | -0.1154 | No |
| 43 | MASP1 | MASP1 Entrez, Source | mannan-binding lectin serine peptidase 1 (C4/C2 activating component of Ra-reactive factor) | 12320 | -0.207 | -0.1034 | No |
| 44 | RGN | RGN Entrez, Source | regucalcin (senescence marker protein-30) | 13038 | -0.386 | -0.1283 | No |
| 45 | LIPC | LIPC Entrez, Source | lipase, hepatic | 13109 | -0.433 | -0.1011 | No |
| 46 | CA3 | CA3 Entrez, Source | carbonic anhydrase III, muscle specific | 13339 | -1.580 | 0.0002 | No |
