Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_single_gel_8d.class.cls #double_gel_8d_versus_single_gel_8d_repos |
| Phenotype | class.cls#double_gel_8d_versus_single_gel_8d_repos |
| Upregulated in class | double_gel_8d |
| GeneSet | LEE_DENA_DN |
| Enrichment Score (ES) | 0.655789 |
| Normalized Enrichment Score (NES) | 2.2316024 |
| Nominal p-value | 0.0 |
| FDR q-value | 6.7218134E-5 |
| FWER p-Value | 0.0020 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | FABP1 | FABP1 Entrez, Source | fatty acid binding protein 1, liver | 8 | 1.205 | 0.0645 | Yes |
| 2 | GLYAT | GLYAT Entrez, Source | glycine-N-acyltransferase | 10 | 1.121 | 0.1250 | Yes |
| 3 | G6PC | G6PC Entrez, Source | glucose-6-phosphatase, catalytic subunit | 21 | 0.893 | 0.1725 | Yes |
| 4 | EHHADH | EHHADH Entrez, Source | enoyl-Coenzyme A, hydratase/3-hydroxyacyl Coenzyme A dehydrogenase | 24 | 0.864 | 0.2191 | Yes |
| 5 | MAT1A | MAT1A Entrez, Source | methionine adenosyltransferase I, alpha | 35 | 0.815 | 0.2624 | Yes |
| 6 | OTC | OTC Entrez, Source | ornithine carbamoyltransferase | 49 | 0.765 | 0.3027 | Yes |
| 7 | PEX11A | PEX11A Entrez, Source | peroxisomal biogenesis factor 11A | 65 | 0.704 | 0.3396 | Yes |
| 8 | CYP2E1 | CYP2E1 Entrez, Source | cytochrome P450, family 2, subfamily E, polypeptide 1 | 87 | 0.637 | 0.3725 | Yes |
| 9 | BHMT | BHMT Entrez, Source | betaine-homocysteine methyltransferase | 140 | 0.550 | 0.3983 | Yes |
| 10 | PCK1 | PCK1 Entrez, Source | phosphoenolpyruvate carboxykinase 1 (soluble) | 167 | 0.505 | 0.4236 | Yes |
| 11 | PON1 | PON1 Entrez, Source | paraoxonase 1 | 193 | 0.481 | 0.4478 | Yes |
| 12 | EPHX2 | EPHX2 Entrez, Source | epoxide hydrolase 2, cytoplasmic | 216 | 0.460 | 0.4710 | Yes |
| 13 | DPYS | DPYS Entrez, Source | dihydropyrimidinase | 253 | 0.432 | 0.4916 | Yes |
| 14 | CPT2 | CPT2 Entrez, Source | carnitine palmitoyltransferase II | 292 | 0.402 | 0.5104 | Yes |
| 15 | ACSL1 | ACSL1 Entrez, Source | acyl-CoA synthetase long-chain family member 1 | 335 | 0.375 | 0.5275 | Yes |
| 16 | SLC27A5 | SLC27A5 Entrez, Source | solute carrier family 27 (fatty acid transporter), member 5 | 392 | 0.341 | 0.5418 | Yes |
| 17 | CYP4F2 | CYP4F2 Entrez, Source | cytochrome P450, family 4, subfamily F, polypeptide 2 | 403 | 0.337 | 0.5593 | Yes |
| 18 | PAH | PAH Entrez, Source | phenylalanine hydroxylase | 411 | 0.336 | 0.5769 | Yes |
| 19 | C4BPA | C4BPA Entrez, Source | complement component 4 binding protein, alpha | 417 | 0.334 | 0.5945 | Yes |
| 20 | ACOX1 | ACOX1 Entrez, Source | acyl-Coenzyme A oxidase 1, palmitoyl | 429 | 0.329 | 0.6115 | Yes |
| 21 | NR1H3 | NR1H3 Entrez, Source | nuclear receptor subfamily 1, group H, member 3 | 540 | 0.287 | 0.6187 | Yes |
| 22 | BAAT | BAAT Entrez, Source | bile acid Coenzyme A: amino acid N-acyltransferase (glycine N-choloyltransferase) | 580 | 0.273 | 0.6305 | Yes |
| 23 | PHYH | PHYH Entrez, Source | phytanoyl-CoA 2-hydroxylase | 849 | 0.214 | 0.6219 | Yes |
| 24 | CYP7A1 | CYP7A1 Entrez, Source | cytochrome P450, family 7, subfamily A, polypeptide 1 | 934 | 0.202 | 0.6265 | Yes |
| 25 | IL1RAP | IL1RAP Entrez, Source | interleukin 1 receptor accessory protein | 1037 | 0.188 | 0.6290 | Yes |
| 26 | ABCD3 | ABCD3 Entrez, Source | ATP-binding cassette, sub-family D (ALD), member 3 | 1076 | 0.184 | 0.6361 | Yes |
| 27 | ACADSB | ACADSB Entrez, Source | acyl-Coenzyme A dehydrogenase, short/branched chain | 1158 | 0.175 | 0.6395 | Yes |
| 28 | HPD | HPD Entrez, Source | 4-hydroxyphenylpyruvate dioxygenase | 1252 | 0.167 | 0.6415 | Yes |
| 29 | ALDH3A2 | ALDH3A2 Entrez, Source | aldehyde dehydrogenase 3 family, member A2 | 1403 | 0.157 | 0.6387 | Yes |
| 30 | OAT | OAT Entrez, Source | ornithine aminotransferase (gyrate atrophy) | 1460 | 0.152 | 0.6427 | Yes |
| 31 | MYH1 | MYH1 Entrez, Source | myosin, heavy chain 1, skeletal muscle, adult | 1512 | 0.148 | 0.6469 | Yes |
| 32 | ME1 | ME1 Entrez, Source | malic enzyme 1, NADP(+)-dependent, cytosolic | 1535 | 0.147 | 0.6532 | Yes |
| 33 | TRPV2 | TRPV2 Entrez, Source | transient receptor potential cation channel, subfamily V, member 2 | 1604 | 0.143 | 0.6558 | Yes |
| 34 | SLC1A2 | SLC1A2 Entrez, Source | solute carrier family 1 (glial high affinity glutamate transporter), member 2 | 1833 | 0.129 | 0.6456 | No |
| 35 | TNNT3 | TNNT3 Entrez, Source | troponin T type 3 (skeletal, fast) | 2118 | 0.117 | 0.6306 | No |
| 36 | SLC2A2 | SLC2A2 Entrez, Source | solute carrier family 2 (facilitated glucose transporter), member 2 | 2969 | 0.086 | 0.5712 | No |
| 37 | TNNI2 | TNNI2 Entrez, Source | troponin I type 2 (skeletal, fast) | 3007 | 0.085 | 0.5730 | No |
| 38 | PADI4 | PADI4 Entrez, Source | peptidyl arginine deiminase, type IV | 3257 | 0.077 | 0.5584 | No |
| 39 | DMBT1 | DMBT1 Entrez, Source | deleted in malignant brain tumors 1 | 3812 | 0.064 | 0.5202 | No |
| 40 | LACTB2 | LACTB2 Entrez, Source | lactamase, beta 2 | 4130 | 0.056 | 0.4993 | No |
| 41 | PNLIPRP1 | PNLIPRP1 Entrez, Source | pancreatic lipase-related protein 1 | 5421 | 0.030 | 0.4038 | No |
| 42 | PRODH | PRODH Entrez, Source | proline dehydrogenase (oxidase) 1 | 5569 | 0.026 | 0.3942 | No |
| 43 | PLA2G1B | PLA2G1B Entrez, Source | phospholipase A2, group IB (pancreas) | 6057 | 0.017 | 0.3585 | No |
| 44 | CTRC | CTRC Entrez, Source | chymotrypsin C (caldecrin) | 6373 | 0.010 | 0.3353 | No |
| 45 | ELA2 | ELA2 Entrez, Source | elastase 2, neutrophil | 6385 | 0.010 | 0.3350 | No |
| 46 | NDRG2 | NDRG2 Entrez, Source | NDRG family member 2 | 6868 | 0.001 | 0.2988 | No |
| 47 | DCXR | DCXR Entrez, Source | dicarbonyl/L-xylulose reductase | 7272 | -0.008 | 0.2688 | No |
| 48 | CYP7B1 | CYP7B1 Entrez, Source | cytochrome P450, family 7, subfamily B, polypeptide 1 | 7432 | -0.011 | 0.2575 | No |
| 49 | CSAD | CSAD Entrez, Source | cysteine sulfinic acid decarboxylase | 8121 | -0.026 | 0.2071 | No |
| 50 | PNLIP | PNLIP Entrez, Source | pancreatic lipase | 9358 | -0.056 | 0.1171 | No |
| 51 | GSTO1 | GSTO1 Entrez, Source | glutathione S-transferase omega 1 | 10091 | -0.078 | 0.0662 | No |
| 52 | HOXA5 | HOXA5 Entrez, Source | homeobox A5 | 10345 | -0.086 | 0.0518 | No |
| 53 | SELENBP1 | SELENBP1 Entrez, Source | selenium binding protein 1 | 10631 | -0.096 | 0.0356 | No |
| 54 | GPR37 | GPR37 Entrez, Source | G protein-coupled receptor 37 (endothelin receptor type B-like) | 11472 | -0.135 | -0.0204 | No |
| 55 | CA5A | CA5A Entrez, Source | carbonic anhydrase VA, mitochondrial | 12440 | -0.220 | -0.0813 | No |
| 56 | ALDH1A1 | ALDH1A1 Entrez, Source | aldehyde dehydrogenase 1 family, member A1 | 12985 | -0.357 | -0.1029 | No |
| 57 | RGN | RGN Entrez, Source | regucalcin (senescence marker protein-30) | 13038 | -0.386 | -0.0860 | No |
| 58 | LIPC | LIPC Entrez, Source | lipase, hepatic | 13109 | -0.433 | -0.0679 | No |
| 59 | CA3 | CA3 Entrez, Source | carbonic anhydrase III, muscle specific | 13339 | -1.580 | 0.0002 | No |
