Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_single_gel_8d.class.cls #double_gel_8d_versus_single_gel_8d_repos |
| Phenotype | class.cls#double_gel_8d_versus_single_gel_8d_repos |
| Upregulated in class | double_gel_8d |
| GeneSet | LEE_E2F1_DN |
| Enrichment Score (ES) | 0.73014516 |
| Normalized Enrichment Score (NES) | 2.3494058 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.0 |
| FWER p-Value | 0.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | FABP1 | FABP1 Entrez, Source | fatty acid binding protein 1, liver | 8 | 1.205 | 0.0979 | Yes |
| 2 | OTC | OTC Entrez, Source | ornithine carbamoyltransferase | 49 | 0.765 | 0.1575 | Yes |
| 3 | GOT1 | GOT1 Entrez, Source | glutamic-oxaloacetic transaminase 1, soluble (aspartate aminotransferase 1) | 56 | 0.731 | 0.2168 | Yes |
| 4 | CYP2E1 | CYP2E1 Entrez, Source | cytochrome P450, family 2, subfamily E, polypeptide 1 | 87 | 0.637 | 0.2666 | Yes |
| 5 | BHMT | BHMT Entrez, Source | betaine-homocysteine methyltransferase | 140 | 0.550 | 0.3077 | Yes |
| 6 | PCK1 | PCK1 Entrez, Source | phosphoenolpyruvate carboxykinase 1 (soluble) | 167 | 0.505 | 0.3470 | Yes |
| 7 | IGF1 | IGF1 Entrez, Source | insulin-like growth factor 1 (somatomedin C) | 236 | 0.445 | 0.3783 | Yes |
| 8 | GHR | GHR Entrez, Source | growth hormone receptor | 312 | 0.389 | 0.4045 | Yes |
| 9 | RARRES1 | RARRES1 Entrez, Source | retinoic acid receptor responder (tazarotene induced) 1 | 325 | 0.381 | 0.4347 | Yes |
| 10 | ACSL1 | ACSL1 Entrez, Source | acyl-CoA synthetase long-chain family member 1 | 335 | 0.375 | 0.4647 | Yes |
| 11 | TDO2 | TDO2 Entrez, Source | tryptophan 2,3-dioxygenase | 355 | 0.360 | 0.4927 | Yes |
| 12 | HADH2 | HADH2 Entrez, Source | hydroxyacyl-Coenzyme A dehydrogenase, type II | 361 | 0.357 | 0.5215 | Yes |
| 13 | PXMP2 | PXMP2 Entrez, Source | peroxisomal membrane protein 2, 22kDa | 380 | 0.350 | 0.5488 | Yes |
| 14 | C4BPA | C4BPA Entrez, Source | complement component 4 binding protein, alpha | 417 | 0.334 | 0.5734 | Yes |
| 15 | PPCS | PPCS Entrez, Source | phosphopantothenoylcysteine synthetase | 466 | 0.313 | 0.5954 | Yes |
| 16 | HSD11B1 | HSD11B1 Entrez, Source | hydroxysteroid (11-beta) dehydrogenase 1 | 487 | 0.306 | 0.6189 | Yes |
| 17 | NR1H3 | NR1H3 Entrez, Source | nuclear receptor subfamily 1, group H, member 3 | 540 | 0.287 | 0.6384 | Yes |
| 18 | KYNU | KYNU Entrez, Source | kynureninase (L-kynurenine hydrolase) | 548 | 0.283 | 0.6610 | Yes |
| 19 | HAL | HAL Entrez, Source | histidine ammonia-lyase | 549 | 0.282 | 0.6841 | Yes |
| 20 | BAAT | BAAT Entrez, Source | bile acid Coenzyme A: amino acid N-acyltransferase (glycine N-choloyltransferase) | 580 | 0.273 | 0.7042 | Yes |
| 21 | IL1RAP | IL1RAP Entrez, Source | interleukin 1 receptor accessory protein | 1037 | 0.188 | 0.6853 | Yes |
| 22 | ITPR1 | ITPR1 Entrez, Source | inositol 1,4,5-triphosphate receptor, type 1 | 1073 | 0.185 | 0.6978 | Yes |
| 23 | DBI | DBI Entrez, Source | diazepam binding inhibitor (GABA receptor modulator, acyl-Coenzyme A binding protein) | 1077 | 0.184 | 0.7126 | Yes |
| 24 | HPD | HPD Entrez, Source | 4-hydroxyphenylpyruvate dioxygenase | 1252 | 0.167 | 0.7132 | Yes |
| 25 | AQP8 | AQP8 Entrez, Source | aquaporin 8 | 1275 | 0.166 | 0.7251 | Yes |
| 26 | OAT | OAT Entrez, Source | ornithine aminotransferase (gyrate atrophy) | 1460 | 0.152 | 0.7237 | Yes |
| 27 | ME1 | ME1 Entrez, Source | malic enzyme 1, NADP(+)-dependent, cytosolic | 1535 | 0.147 | 0.7301 | Yes |
| 28 | SERPINF1 | SERPINF1 Entrez, Source | serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 | 1787 | 0.132 | 0.7221 | No |
| 29 | CFH | CFH Entrez, Source | complement factor H | 2176 | 0.115 | 0.7023 | No |
| 30 | MDH1 | MDH1 Entrez, Source | malate dehydrogenase 1, NAD (soluble) | 2361 | 0.108 | 0.6973 | No |
| 31 | ELOVL5 | ELOVL5 Entrez, Source | ELOVL family member 5, elongation of long chain fatty acids (FEN1/Elo2, SUR4/Elo3-like, yeast) | 2393 | 0.107 | 0.7038 | No |
| 32 | ADIPOR2 | ADIPOR2 Entrez, Source | adiponectin receptor 2 | 3114 | 0.081 | 0.6562 | No |
| 33 | ABCG2 | ABCG2 Entrez, Source | ATP-binding cassette, sub-family G (WHITE), member 2 | 3807 | 0.064 | 0.6094 | No |
| 34 | PNLIPRP1 | PNLIPRP1 Entrez, Source | pancreatic lipase-related protein 1 | 5421 | 0.030 | 0.4906 | No |
| 35 | CTRC | CTRC Entrez, Source | chymotrypsin C (caldecrin) | 6373 | 0.010 | 0.4199 | No |
| 36 | ELA2 | ELA2 Entrez, Source | elastase 2, neutrophil | 6385 | 0.010 | 0.4199 | No |
| 37 | ZG16 | ZG16 Entrez, Source | - | 7053 | -0.003 | 0.3700 | No |
| 38 | MAPKAPK2 | MAPKAPK2 Entrez, Source | mitogen-activated protein kinase-activated protein kinase 2 | 8907 | -0.044 | 0.2342 | No |
| 39 | PNLIP | PNLIP Entrez, Source | pancreatic lipase | 9358 | -0.056 | 0.2049 | No |
| 40 | GSTO1 | GSTO1 Entrez, Source | glutathione S-transferase omega 1 | 10091 | -0.078 | 0.1563 | No |
| 41 | EGFR | EGFR Entrez, Source | epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian) | 10171 | -0.080 | 0.1569 | No |
| 42 | AKAP11 | AKAP11 Entrez, Source | A kinase (PRKA) anchor protein 11 | 11090 | -0.116 | 0.0974 | No |
| 43 | GPR37 | GPR37 Entrez, Source | G protein-coupled receptor 37 (endothelin receptor type B-like) | 11472 | -0.135 | 0.0798 | No |
| 44 | ALDH1A1 | ALDH1A1 Entrez, Source | aldehyde dehydrogenase 1 family, member A1 | 12985 | -0.357 | -0.0048 | No |
| 45 | RGN | RGN Entrez, Source | regucalcin (senescence marker protein-30) | 13038 | -0.386 | 0.0229 | No |
