Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_single_gel_8d.class.cls #double_gel_8d_versus_single_gel_8d_repos |
| Phenotype | class.cls#double_gel_8d_versus_single_gel_8d_repos |
| Upregulated in class | double_gel_8d |
| GeneSet | LEE_MYC_DN |
| Enrichment Score (ES) | 0.7732309 |
| Normalized Enrichment Score (NES) | 2.4574978 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.0 |
| FWER p-Value | 0.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | G0S2 | G0S2 Entrez, Source | G0/G1switch 2 | 6 | 1.218 | 0.0936 | Yes |
| 2 | G6PC | G6PC Entrez, Source | glucose-6-phosphatase, catalytic subunit | 21 | 0.893 | 0.1615 | Yes |
| 3 | RGS16 | RGS16 Entrez, Source | regulator of G-protein signalling 16 | 42 | 0.784 | 0.2205 | Yes |
| 4 | OTC | OTC Entrez, Source | ornithine carbamoyltransferase | 49 | 0.765 | 0.2792 | Yes |
| 5 | GOT1 | GOT1 Entrez, Source | glutamic-oxaloacetic transaminase 1, soluble (aspartate aminotransferase 1) | 56 | 0.731 | 0.3351 | Yes |
| 6 | PFKFB1 | PFKFB1 Entrez, Source | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 | 95 | 0.621 | 0.3802 | Yes |
| 7 | BHMT | BHMT Entrez, Source | betaine-homocysteine methyltransferase | 140 | 0.550 | 0.4194 | Yes |
| 8 | PCK1 | PCK1 Entrez, Source | phosphoenolpyruvate carboxykinase 1 (soluble) | 167 | 0.505 | 0.4565 | Yes |
| 9 | DPYD | DPYD Entrez, Source | dihydropyrimidine dehydrogenase | 168 | 0.502 | 0.4952 | Yes |
| 10 | KLF15 | KLF15 Entrez, Source | Kruppel-like factor 15 | 200 | 0.476 | 0.5297 | Yes |
| 11 | IGF1 | IGF1 Entrez, Source | insulin-like growth factor 1 (somatomedin C) | 236 | 0.445 | 0.5614 | Yes |
| 12 | RARRES1 | RARRES1 Entrez, Source | retinoic acid receptor responder (tazarotene induced) 1 | 325 | 0.381 | 0.5842 | Yes |
| 13 | TDO2 | TDO2 Entrez, Source | tryptophan 2,3-dioxygenase | 355 | 0.360 | 0.6098 | Yes |
| 14 | IGFBP2 | IGFBP2 Entrez, Source | insulin-like growth factor binding protein 2, 36kDa | 378 | 0.352 | 0.6353 | Yes |
| 15 | FKBP5 | FKBP5 Entrez, Source | FK506 binding protein 5 | 405 | 0.337 | 0.6594 | Yes |
| 16 | C4BPA | C4BPA Entrez, Source | complement component 4 binding protein, alpha | 417 | 0.334 | 0.6843 | Yes |
| 17 | HERPUD1 | HERPUD1 Entrez, Source | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | 425 | 0.331 | 0.7094 | Yes |
| 18 | KYNU | KYNU Entrez, Source | kynureninase (L-kynurenine hydrolase) | 548 | 0.283 | 0.7220 | Yes |
| 19 | HAL | HAL Entrez, Source | histidine ammonia-lyase | 549 | 0.282 | 0.7438 | Yes |
| 20 | SLC37A4 | SLC37A4 Entrez, Source | solute carrier family 37 (glycerol-6-phosphate transporter), member 4 | 675 | 0.246 | 0.7534 | Yes |
| 21 | HRSP12 | HRSP12 Entrez, Source | heat-responsive protein 12 | 737 | 0.230 | 0.7666 | Yes |
| 22 | IGF2 | IGF2 Entrez, Source | insulin-like growth factor 2 (somatomedin A) | 867 | 0.212 | 0.7732 | Yes |
| 23 | HSPA5 | HSPA5 Entrez, Source | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 1061 | 0.186 | 0.7731 | No |
| 24 | AQP8 | AQP8 Entrez, Source | aquaporin 8 | 1275 | 0.166 | 0.7699 | No |
| 25 | SFXN1 | SFXN1 Entrez, Source | sideroflexin 1 | 1452 | 0.153 | 0.7685 | No |
| 26 | CFH | CFH Entrez, Source | complement factor H | 2176 | 0.115 | 0.7230 | No |
| 27 | ELOVL5 | ELOVL5 Entrez, Source | ELOVL family member 5, elongation of long chain fatty acids (FEN1/Elo2, SUR4/Elo3-like, yeast) | 2393 | 0.107 | 0.7150 | No |
| 28 | DMBT1 | DMBT1 Entrez, Source | deleted in malignant brain tumors 1 | 3812 | 0.064 | 0.6133 | No |
| 29 | FGG | FGG Entrez, Source | fibrinogen gamma chain | 4933 | 0.039 | 0.5322 | No |
| 30 | PNLIPRP1 | PNLIPRP1 Entrez, Source | pancreatic lipase-related protein 1 | 5421 | 0.030 | 0.4978 | No |
| 31 | CTRC | CTRC Entrez, Source | chymotrypsin C (caldecrin) | 6373 | 0.010 | 0.4271 | No |
| 32 | ELA2 | ELA2 Entrez, Source | elastase 2, neutrophil | 6385 | 0.010 | 0.4271 | No |
| 33 | ZG16 | ZG16 Entrez, Source | - | 7053 | -0.003 | 0.3772 | No |
| 34 | MEOX2 | MEOX2 Entrez, Source | mesenchyme homeobox 2 | 7421 | -0.011 | 0.3504 | No |
| 35 | MAPKAPK2 | MAPKAPK2 Entrez, Source | mitogen-activated protein kinase-activated protein kinase 2 | 8907 | -0.044 | 0.2421 | No |
| 36 | PNLIP | PNLIP Entrez, Source | pancreatic lipase | 9358 | -0.056 | 0.2126 | No |
| 37 | EFEMP1 | EFEMP1 Entrez, Source | EGF-containing fibulin-like extracellular matrix protein 1 | 9375 | -0.057 | 0.2158 | No |
| 38 | EGFR | EGFR Entrez, Source | epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian) | 10171 | -0.080 | 0.1622 | No |
| 39 | HBP1 | HBP1 Entrez, Source | HMG-box transcription factor 1 | 10662 | -0.097 | 0.1329 | No |
| 40 | PCOLCE | PCOLCE Entrez, Source | procollagen C-endopeptidase enhancer | 11861 | -0.161 | 0.0552 | No |
| 41 | HSPH1 | HSPH1 Entrez, Source | heat shock 105kDa/110kDa protein 1 | 11957 | -0.169 | 0.0612 | No |
| 42 | SATB1 | SATB1 Entrez, Source | special AT-rich sequence binding protein 1 (binds to nuclear matrix/scaffold-associating DNA's) | 12659 | -0.255 | 0.0281 | No |
| 43 | IL1R1 | IL1R1 Entrez, Source | interleukin 1 receptor, type I | 12840 | -0.300 | 0.0377 | No |
