Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_single_gel_8d.class.cls #double_gel_8d_versus_single_gel_8d_repos |
| Phenotype | class.cls#double_gel_8d_versus_single_gel_8d_repos |
| Upregulated in class | double_gel_8d |
| GeneSet | LEE_MYC_E2F1_DN |
| Enrichment Score (ES) | 0.82981414 |
| Normalized Enrichment Score (NES) | 2.7043836 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.0 |
| FWER p-Value | 0.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | G0S2 | G0S2 Entrez, Source | G0/G1switch 2 | 6 | 1.218 | 0.0738 | Yes |
| 2 | FABP1 | FABP1 Entrez, Source | fatty acid binding protein 1, liver | 8 | 1.205 | 0.1471 | Yes |
| 3 | G6PC | G6PC Entrez, Source | glucose-6-phosphatase, catalytic subunit | 21 | 0.893 | 0.2005 | Yes |
| 4 | MAT1A | MAT1A Entrez, Source | methionine adenosyltransferase I, alpha | 35 | 0.815 | 0.2492 | Yes |
| 5 | RGS16 | RGS16 Entrez, Source | regulator of G-protein signalling 16 | 42 | 0.784 | 0.2964 | Yes |
| 6 | OTC | OTC Entrez, Source | ornithine carbamoyltransferase | 49 | 0.765 | 0.3426 | Yes |
| 7 | GOT1 | GOT1 Entrez, Source | glutamic-oxaloacetic transaminase 1, soluble (aspartate aminotransferase 1) | 56 | 0.731 | 0.3866 | Yes |
| 8 | FABP2 | FABP2 Entrez, Source | fatty acid binding protein 2, intestinal | 71 | 0.690 | 0.4276 | Yes |
| 9 | CYP2E1 | CYP2E1 Entrez, Source | cytochrome P450, family 2, subfamily E, polypeptide 1 | 87 | 0.637 | 0.4652 | Yes |
| 10 | BHMT | BHMT Entrez, Source | betaine-homocysteine methyltransferase | 140 | 0.550 | 0.4948 | Yes |
| 11 | PCK1 | PCK1 Entrez, Source | phosphoenolpyruvate carboxykinase 1 (soluble) | 167 | 0.505 | 0.5236 | Yes |
| 12 | EPHX2 | EPHX2 Entrez, Source | epoxide hydrolase 2, cytoplasmic | 216 | 0.460 | 0.5480 | Yes |
| 13 | IGF1 | IGF1 Entrez, Source | insulin-like growth factor 1 (somatomedin C) | 236 | 0.445 | 0.5737 | Yes |
| 14 | GHR | GHR Entrez, Source | growth hormone receptor | 312 | 0.389 | 0.5917 | Yes |
| 15 | RARRES1 | RARRES1 Entrez, Source | retinoic acid receptor responder (tazarotene induced) 1 | 325 | 0.381 | 0.6140 | Yes |
| 16 | ACSL1 | ACSL1 Entrez, Source | acyl-CoA synthetase long-chain family member 1 | 335 | 0.375 | 0.6362 | Yes |
| 17 | TDO2 | TDO2 Entrez, Source | tryptophan 2,3-dioxygenase | 355 | 0.360 | 0.6567 | Yes |
| 18 | IGFBP2 | IGFBP2 Entrez, Source | insulin-like growth factor binding protein 2, 36kDa | 378 | 0.352 | 0.6764 | Yes |
| 19 | PXMP2 | PXMP2 Entrez, Source | peroxisomal membrane protein 2, 22kDa | 380 | 0.350 | 0.6977 | Yes |
| 20 | CYP4F2 | CYP4F2 Entrez, Source | cytochrome P450, family 4, subfamily F, polypeptide 2 | 403 | 0.337 | 0.7166 | Yes |
| 21 | C4BPA | C4BPA Entrez, Source | complement component 4 binding protein, alpha | 417 | 0.334 | 0.7359 | Yes |
| 22 | HSD11B1 | HSD11B1 Entrez, Source | hydroxysteroid (11-beta) dehydrogenase 1 | 487 | 0.306 | 0.7494 | Yes |
| 23 | SLC25A22 | SLC25A22 Entrez, Source | solute carrier family 25 (mitochondrial carrier: glutamate), member 22 | 488 | 0.305 | 0.7679 | Yes |
| 24 | NR1H3 | NR1H3 Entrez, Source | nuclear receptor subfamily 1, group H, member 3 | 540 | 0.287 | 0.7815 | Yes |
| 25 | KYNU | KYNU Entrez, Source | kynureninase (L-kynurenine hydrolase) | 548 | 0.283 | 0.7982 | Yes |
| 26 | HAL | HAL Entrez, Source | histidine ammonia-lyase | 549 | 0.282 | 0.8154 | Yes |
| 27 | BAAT | BAAT Entrez, Source | bile acid Coenzyme A: amino acid N-acyltransferase (glycine N-choloyltransferase) | 580 | 0.273 | 0.8298 | Yes |
| 28 | IL1RAP | IL1RAP Entrez, Source | interleukin 1 receptor accessory protein | 1037 | 0.188 | 0.8070 | No |
| 29 | ABCD3 | ABCD3 Entrez, Source | ATP-binding cassette, sub-family D (ALD), member 3 | 1076 | 0.184 | 0.8153 | No |
| 30 | HPD | HPD Entrez, Source | 4-hydroxyphenylpyruvate dioxygenase | 1252 | 0.167 | 0.8124 | No |
| 31 | ALAD | ALAD Entrez, Source | aminolevulinate, delta-, dehydratase | 1424 | 0.155 | 0.8090 | No |
| 32 | OAT | OAT Entrez, Source | ornithine aminotransferase (gyrate atrophy) | 1460 | 0.152 | 0.8156 | No |
| 33 | ME1 | ME1 Entrez, Source | malic enzyme 1, NADP(+)-dependent, cytosolic | 1535 | 0.147 | 0.8190 | No |
| 34 | TRPV2 | TRPV2 Entrez, Source | transient receptor potential cation channel, subfamily V, member 2 | 1604 | 0.143 | 0.8226 | No |
| 35 | ELOVL5 | ELOVL5 Entrez, Source | ELOVL family member 5, elongation of long chain fatty acids (FEN1/Elo2, SUR4/Elo3-like, yeast) | 2393 | 0.107 | 0.7698 | No |
| 36 | SFTPD | SFTPD Entrez, Source | surfactant, pulmonary-associated protein D | 3017 | 0.084 | 0.7281 | No |
| 37 | ADIPOR2 | ADIPOR2 Entrez, Source | adiponectin receptor 2 | 3114 | 0.081 | 0.7259 | No |
| 38 | PNLIPRP1 | PNLIPRP1 Entrez, Source | pancreatic lipase-related protein 1 | 5421 | 0.030 | 0.5542 | No |
| 39 | CTRC | CTRC Entrez, Source | chymotrypsin C (caldecrin) | 6373 | 0.010 | 0.4833 | No |
| 40 | ELA2 | ELA2 Entrez, Source | elastase 2, neutrophil | 6385 | 0.010 | 0.4831 | No |
| 41 | CYP7B1 | CYP7B1 Entrez, Source | cytochrome P450, family 7, subfamily B, polypeptide 1 | 7432 | -0.011 | 0.4051 | No |
| 42 | CPOX | CPOX Entrez, Source | coproporphyrinogen oxidase | 8432 | -0.033 | 0.3320 | No |
| 43 | MAPKAPK2 | MAPKAPK2 Entrez, Source | mitogen-activated protein kinase-activated protein kinase 2 | 8907 | -0.044 | 0.2990 | No |
| 44 | EGFR | EGFR Entrez, Source | epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian) | 10171 | -0.080 | 0.2089 | No |
| 45 | HBP1 | HBP1 Entrez, Source | HMG-box transcription factor 1 | 10662 | -0.097 | 0.1780 | No |
| 46 | RGN | RGN Entrez, Source | regucalcin (senescence marker protein-30) | 13038 | -0.386 | 0.0229 | No |
