Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_single_gel_8d.class.cls #double_gel_8d_versus_single_gel_8d_repos |
| Phenotype | class.cls#double_gel_8d_versus_single_gel_8d_repos |
| Upregulated in class | double_gel_8d |
| GeneSet | LIGAND_DEPENDENT_NUCLEAR_RECEPTOR_ACTIVITY |
| Enrichment Score (ES) | 0.5721423 |
| Normalized Enrichment Score (NES) | 1.5437866 |
| Nominal p-value | 0.026431719 |
| FDR q-value | 0.09824021 |
| FWER p-Value | 1.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | NR1I3 | NR1I3 Entrez, Source | nuclear receptor subfamily 1, group I, member 3 | 47 | 0.769 | 0.2217 | Yes |
| 2 | RARB | RARB Entrez, Source | retinoic acid receptor, beta | 101 | 0.614 | 0.3976 | Yes |
| 3 | RXRA | RXRA Entrez, Source | retinoid X receptor, alpha | 375 | 0.353 | 0.4805 | Yes |
| 4 | RXRG | RXRG Entrez, Source | retinoid X receptor, gamma | 490 | 0.304 | 0.5609 | Yes |
| 5 | AR | AR Entrez, Source | androgen receptor (dihydrotestosterone receptor; testicular feminization; spinal and bulbar muscular atrophy; Kennedy disease) | 1135 | 0.178 | 0.5646 | Yes |
| 6 | ESR2 | ESR2 Entrez, Source | estrogen receptor 2 (ER beta) | 1837 | 0.129 | 0.5498 | Yes |
| 7 | THRB | THRB Entrez, Source | thyroid hormone receptor, beta (erythroblastic leukemia viral (v-erb-a) oncogene homolog 2, avian) | 2013 | 0.121 | 0.5721 | Yes |
| 8 | VDR | VDR Entrez, Source | vitamin D (1,25- dihydroxyvitamin D3) receptor | 2521 | 0.102 | 0.5639 | No |
| 9 | PGRMC2 | PGRMC2 Entrez, Source | progesterone receptor membrane component 2 | 3016 | 0.084 | 0.5516 | No |
| 10 | PPARD | PPARD Entrez, Source | peroxisome proliferative activated receptor, delta | 3231 | 0.078 | 0.5582 | No |
| 11 | NR3C1 | NR3C1 Entrez, Source | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 4791 | 0.042 | 0.4535 | No |
| 12 | PGR | PGR Entrez, Source | progesterone receptor | 5058 | 0.037 | 0.4444 | No |
| 13 | NR2F6 | NR2F6 Entrez, Source | nuclear receptor subfamily 2, group F, member 6 | 5110 | 0.036 | 0.4510 | No |
| 14 | PTGER3 | PTGER3 Entrez, Source | prostaglandin E receptor 3 (subtype EP3) | 5626 | 0.025 | 0.4196 | No |
| 15 | NR4A3 | NR4A3 Entrez, Source | nuclear receptor subfamily 4, group A, member 3 | 5891 | 0.020 | 0.4058 | No |
| 16 | THRA | THRA Entrez, Source | thyroid hormone receptor, alpha (erythroblastic leukemia viral (v-erb-a) oncogene homolog, avian) | 5968 | 0.019 | 0.4056 | No |
| 17 | NR1D1 | NR1D1 Entrez, Source | nuclear receptor subfamily 1, group D, member 1 | 6399 | 0.010 | 0.3762 | No |
| 18 | RARA | RARA Entrez, Source | retinoic acid receptor, alpha | 9483 | -0.059 | 0.1621 | No |
| 19 | RXRB | RXRB Entrez, Source | retinoid X receptor, beta | 9739 | -0.066 | 0.1623 | No |
| 20 | NR3C2 | NR3C2 Entrez, Source | nuclear receptor subfamily 3, group C, member 2 | 10284 | -0.084 | 0.1462 | No |
| 21 | AHR | AHR Entrez, Source | aryl hydrocarbon receptor | 11529 | -0.139 | 0.0935 | No |
| 22 | BRD8 | BRD8 Entrez, Source | bromodomain containing 8 | 11629 | -0.145 | 0.1286 | No |
