Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_single_gel_8d.class.cls #double_gel_8d_versus_single_gel_8d_repos |
| Phenotype | class.cls#double_gel_8d_versus_single_gel_8d_repos |
| Upregulated in class | single_gel_8d |
| GeneSet | LI_FETAL_VS_WT_KIDNEY_DN |
| Enrichment Score (ES) | -0.49144244 |
| Normalized Enrichment Score (NES) | -1.7243685 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.07056003 |
| FWER p-Value | 0.999 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | FADS2 | FADS2 Entrez, Source | fatty acid desaturase 2 | 98 | 0.617 | 0.0383 | No |
| 2 | FADS1 | FADS1 Entrez, Source | fatty acid desaturase 1 | 401 | 0.338 | 0.0405 | No |
| 3 | IGSF4 | IGSF4 Entrez, Source | immunoglobulin superfamily, member 4 | 821 | 0.218 | 0.0251 | No |
| 4 | SHMT2 | SHMT2 Entrez, Source | serine hydroxymethyltransferase 2 (mitochondrial) | 1105 | 0.181 | 0.0171 | No |
| 5 | NELL2 | NELL2 Entrez, Source | NEL-like 2 (chicken) | 1138 | 0.178 | 0.0279 | No |
| 6 | YARS | YARS Entrez, Source | tyrosyl-tRNA synthetase | 1355 | 0.160 | 0.0235 | No |
| 7 | HMGA2 | HMGA2 Entrez, Source | high mobility group AT-hook 2 | 2267 | 0.112 | -0.0370 | No |
| 8 | CHN1 | CHN1 Entrez, Source | chimerin (chimaerin) 1 | 2335 | 0.109 | -0.0340 | No |
| 9 | CDH2 | CDH2 Entrez, Source | cadherin 2, type 1, N-cadherin (neuronal) | 2409 | 0.106 | -0.0316 | No |
| 10 | ASNS | ASNS Entrez, Source | asparagine synthetase | 2424 | 0.106 | -0.0248 | No |
| 11 | ABCA2 | ABCA2 Entrez, Source | ATP-binding cassette, sub-family A (ABC1), member 2 | 2754 | 0.094 | -0.0427 | No |
| 12 | SLC16A1 | SLC16A1 Entrez, Source | solute carrier family 16, member 1 (monocarboxylic acid transporter 1) | 2935 | 0.087 | -0.0499 | No |
| 13 | XRCC5 | XRCC5 Entrez, Source | X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining; Ku autoantigen, 80kDa) | 2976 | 0.086 | -0.0465 | No |
| 14 | BAZ1B | BAZ1B Entrez, Source | bromodomain adjacent to zinc finger domain, 1B | 3100 | 0.082 | -0.0498 | No |
| 15 | ADIPOR2 | ADIPOR2 Entrez, Source | adiponectin receptor 2 | 3114 | 0.081 | -0.0447 | No |
| 16 | UNG | UNG Entrez, Source | uracil-DNA glycosylase | 3194 | 0.079 | -0.0449 | No |
| 17 | ST6GAL1 | ST6GAL1 Entrez, Source | ST6 beta-galactosamide alpha-2,6-sialyltranferase 1 | 3300 | 0.076 | -0.0472 | No |
| 18 | DKC1 | DKC1 Entrez, Source | dyskeratosis congenita 1, dyskerin | 3627 | 0.068 | -0.0667 | No |
| 19 | CDK2 | CDK2 Entrez, Source | cyclin-dependent kinase 2 | 3808 | 0.064 | -0.0756 | No |
| 20 | PFKP | PFKP Entrez, Source | phosphofructokinase, platelet | 4054 | 0.058 | -0.0897 | No |
| 21 | COL2A1 | COL2A1 Entrez, Source | collagen, type II, alpha 1 (primary osteoarthritis, spondyloepiphyseal dysplasia, congenital) | 4714 | 0.044 | -0.1362 | No |
| 22 | PARP1 | PARP1 Entrez, Source | poly (ADP-ribose) polymerase family, member 1 | 5026 | 0.037 | -0.1569 | No |
| 23 | ACP1 | ACP1 Entrez, Source | acid phosphatase 1, soluble | 5200 | 0.034 | -0.1674 | No |
| 24 | CXCR4 | CXCR4 Entrez, Source | chemokine (C-X-C motif) receptor 4 | 5204 | 0.034 | -0.1651 | No |
| 25 | DDX52 | DDX52 Entrez, Source | DEAD (Asp-Glu-Ala-Asp) box polypeptide 52 | 5451 | 0.029 | -0.1815 | No |
| 26 | GTF3C2 | GTF3C2 Entrez, Source | general transcription factor IIIC, polypeptide 2, beta 110kDa | 5481 | 0.028 | -0.1816 | No |
| 27 | GARS | GARS Entrez, Source | glycyl-tRNA synthetase | 5484 | 0.028 | -0.1797 | No |
| 28 | STRAP | STRAP Entrez, Source | serine/threonine kinase receptor associated protein | 6387 | 0.010 | -0.2470 | No |
| 29 | TOP2A | TOP2A Entrez, Source | topoisomerase (DNA) II alpha 170kDa | 6709 | 0.004 | -0.2709 | No |
| 30 | NAP1L1 | NAP1L1 Entrez, Source | nucleosome assembly protein 1-like 1 | 6915 | -0.000 | -0.2864 | No |
| 31 | NME1 | NME1 Entrez, Source | non-metastatic cells 1, protein (NM23A) expressed in | 8399 | -0.032 | -0.3958 | No |
| 32 | H2AFZ | H2AFZ Entrez, Source | H2A histone family, member Z | 8540 | -0.035 | -0.4038 | No |
| 33 | POLE3 | POLE3 Entrez, Source | polymerase (DNA directed), epsilon 3 (p17 subunit) | 8809 | -0.041 | -0.4209 | No |
| 34 | NASP | NASP Entrez, Source | nuclear autoantigenic sperm protein (histone-binding) | 8949 | -0.045 | -0.4281 | No |
| 35 | TARBP2 | TARBP2 Entrez, Source | Tar (HIV-1) RNA binding protein 2 | 9013 | -0.046 | -0.4294 | No |
| 36 | SPAG5 | SPAG5 Entrez, Source | sperm associated antigen 5 | 9056 | -0.048 | -0.4291 | No |
| 37 | NOLC1 | NOLC1 Entrez, Source | nucleolar and coiled-body phosphoprotein 1 | 9128 | -0.050 | -0.4308 | No |
| 38 | CDKN3 | CDKN3 Entrez, Source | cyclin-dependent kinase inhibitor 3 (CDK2-associated dual specificity phosphatase) | 9252 | -0.053 | -0.4361 | No |
| 39 | DDX1 | DDX1 Entrez, Source | DEAD (Asp-Glu-Ala-Asp) box polypeptide 1 | 9530 | -0.061 | -0.4525 | No |
| 40 | SV2A | SV2A Entrez, Source | synaptic vesicle glycoprotein 2A | 9631 | -0.064 | -0.4554 | No |
| 41 | SIX1 | SIX1 Entrez, Source | sine oculis homeobox homolog 1 (Drosophila) | 9691 | -0.065 | -0.4550 | No |
| 42 | PCBP2 | PCBP2 Entrez, Source | poly(rC) binding protein 2 | 10175 | -0.081 | -0.4855 | Yes |
| 43 | KIFC1 | KIFC1 Entrez, Source | kinesin family member C1 | 10247 | -0.083 | -0.4847 | Yes |
| 44 | LRP4 | LRP4 Entrez, Source | low density lipoprotein receptor-related protein 4 | 10260 | -0.083 | -0.4794 | Yes |
| 45 | LIG3 | LIG3 Entrez, Source | ligase III, DNA, ATP-dependent | 10312 | -0.085 | -0.4770 | Yes |
| 46 | BUB1B | BUB1B Entrez, Source | BUB1 budding uninhibited by benzimidazoles 1 homolog beta (yeast) | 10391 | -0.088 | -0.4764 | Yes |
| 47 | CHST1 | CHST1 Entrez, Source | carbohydrate (keratan sulfate Gal-6) sulfotransferase 1 | 10469 | -0.091 | -0.4754 | Yes |
| 48 | NUP188 | NUP188 Entrez, Source | nucleoporin 188kDa | 10535 | -0.093 | -0.4735 | Yes |
| 49 | CRABP2 | CRABP2 Entrez, Source | cellular retinoic acid binding protein 2 | 10545 | -0.093 | -0.4673 | Yes |
| 50 | RNASEH2A | RNASEH2A Entrez, Source | ribonuclease H2, subunit A | 10571 | -0.094 | -0.4622 | Yes |
| 51 | SSRP1 | SSRP1 Entrez, Source | structure specific recognition protein 1 | 10636 | -0.096 | -0.4599 | Yes |
| 52 | PCNA | PCNA Entrez, Source | proliferating cell nuclear antigen | 10651 | -0.097 | -0.4538 | Yes |
| 53 | SRPK1 | SRPK1 Entrez, Source | SFRS protein kinase 1 | 10734 | -0.100 | -0.4526 | Yes |
| 54 | CCT3 | CCT3 Entrez, Source | chaperonin containing TCP1, subunit 3 (gamma) | 10769 | -0.102 | -0.4476 | Yes |
| 55 | BUB3 | BUB3 Entrez, Source | BUB3 budding uninhibited by benzimidazoles 3 homolog (yeast) | 10991 | -0.111 | -0.4560 | Yes |
| 56 | CDC20 | CDC20 Entrez, Source | CDC20 cell division cycle 20 homolog (S. cerevisiae) | 11099 | -0.117 | -0.4555 | Yes |
| 57 | PPP2R2A | PPP2R2A Entrez, Source | protein phosphatase 2 (formerly 2A), regulatory subunit B (PR 52), alpha isoform | 11243 | -0.124 | -0.4571 | Yes |
| 58 | LMNB1 | LMNB1 Entrez, Source | lamin B1 | 11329 | -0.128 | -0.4541 | Yes |
| 59 | SS18 | SS18 Entrez, Source | synovial sarcoma translocation, chromosome 18 | 11353 | -0.129 | -0.4462 | Yes |
| 60 | BRCA1 | BRCA1 Entrez, Source | breast cancer 1, early onset | 11523 | -0.139 | -0.4487 | Yes |
| 61 | TIA1 | TIA1 Entrez, Source | TIA1 cytotoxic granule-associated RNA binding protein | 11579 | -0.142 | -0.4423 | Yes |
| 62 | PTTG1 | PTTG1 Entrez, Source | pituitary tumor-transforming 1 | 11624 | -0.145 | -0.4349 | Yes |
| 63 | CIT | CIT Entrez, Source | citron (rho-interacting, serine/threonine kinase 21) | 11639 | -0.146 | -0.4252 | Yes |
| 64 | FAM62A | FAM62A Entrez, Source | family with sequence similarity 62 (C2 domain containing), member A | 11823 | -0.159 | -0.4272 | Yes |
| 65 | YWHAZ | YWHAZ Entrez, Source | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide | 11826 | -0.159 | -0.4156 | Yes |
| 66 | KIF2C | KIF2C Entrez, Source | kinesin family member 2C | 11889 | -0.164 | -0.4082 | Yes |
| 67 | TXNRD1 | TXNRD1 Entrez, Source | thioredoxin reductase 1 | 11903 | -0.166 | -0.3969 | Yes |
| 68 | SMC4 | SMC4 Entrez, Source | structural maintenance of chromosomes 4 | 11916 | -0.167 | -0.3855 | Yes |
| 69 | MSH2 | MSH2 Entrez, Source | mutS homolog 2, colon cancer, nonpolyposis type 1 (E. coli) | 12401 | -0.215 | -0.4061 | Yes |
| 70 | PRIM2A | PRIM2A Entrez, Source | primase, polypeptide 2A, 58kDa | 12498 | -0.229 | -0.3964 | Yes |
| 71 | AURKA | AURKA Entrez, Source | aurora kinase A | 12548 | -0.235 | -0.3827 | Yes |
| 72 | CKAP5 | CKAP5 Entrez, Source | cytoskeleton associated protein 5 | 12613 | -0.247 | -0.3692 | Yes |
| 73 | TIMELESS | TIMELESS Entrez, Source | timeless homolog (Drosophila) | 12644 | -0.253 | -0.3527 | Yes |
| 74 | FEN1 | FEN1 Entrez, Source | flap structure-specific endonuclease 1 | 12720 | -0.269 | -0.3385 | Yes |
| 75 | TRIP13 | TRIP13 Entrez, Source | thyroid hormone receptor interactor 13 | 12822 | -0.294 | -0.3243 | Yes |
| 76 | CCNB2 | CCNB2 Entrez, Source | cyclin B2 | 12954 | -0.340 | -0.3090 | Yes |
| 77 | CACNB3 | CACNB3 Entrez, Source | calcium channel, voltage-dependent, beta 3 subunit | 12957 | -0.341 | -0.2839 | Yes |
| 78 | PRIM1 | PRIM1 Entrez, Source | primase, polypeptide 1, 49kDa | 12999 | -0.364 | -0.2600 | Yes |
| 79 | CCND2 | CCND2 Entrez, Source | cyclin D2 | 13016 | -0.374 | -0.2335 | Yes |
| 80 | GPC1 | GPC1 Entrez, Source | glypican 1 | 13081 | -0.412 | -0.2078 | Yes |
| 81 | AURKB | AURKB Entrez, Source | aurora kinase B | 13112 | -0.438 | -0.1776 | Yes |
| 82 | KIAA0101 | KIAA0101 Entrez, Source | KIAA0101 | 13128 | -0.448 | -0.1456 | Yes |
| 83 | SCRN1 | SCRN1 Entrez, Source | secernin 1 | 13182 | -0.529 | -0.1104 | Yes |
| 84 | STMN1 | STMN1 Entrez, Source | stathmin 1/oncoprotein 18 | 13288 | -0.823 | -0.0574 | Yes |
| 85 | MCM6 | MCM6 Entrez, Source | MCM6 minichromosome maintenance deficient 6 (MIS5 homolog, S. pombe) (S. cerevisiae) | 13289 | -0.828 | 0.0040 | Yes |
