Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_single_gel_8d.class.cls #double_gel_8d_versus_single_gel_8d_repos |
| Phenotype | class.cls#double_gel_8d_versus_single_gel_8d_repos |
| Upregulated in class | single_gel_8d |
| GeneSet | MATRIX_METALLOPROTEINASES |
| Enrichment Score (ES) | -0.7652333 |
| Normalized Enrichment Score (NES) | -1.9185945 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.021304037 |
| FWER p-Value | 0.386 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | ARAF | ARAF Entrez, Source | v-raf murine sarcoma 3611 viral oncogene homolog | 1896 | 0.126 | -0.1140 | No |
| 2 | MMP3 | MMP3 Entrez, Source | matrix metallopeptidase 3 (stromelysin 1, progelatinase) | 2981 | 0.085 | -0.1763 | No |
| 3 | TNF | TNF Entrez, Source | tumor necrosis factor (TNF superfamily, member 2) | 3489 | 0.071 | -0.1984 | No |
| 4 | MMP7 | MMP7 Entrez, Source | matrix metallopeptidase 7 (matrilysin, uterine) | 3931 | 0.061 | -0.2178 | No |
| 5 | MMP12 | MMP12 Entrez, Source | matrix metallopeptidase 12 (macrophage elastase) | 4703 | 0.044 | -0.2659 | No |
| 6 | MMP8 | MMP8 Entrez, Source | matrix metallopeptidase 8 (neutrophil collagenase) | 6715 | 0.004 | -0.4159 | No |
| 7 | BSG | BSG Entrez, Source | basigin (Ok blood group) | 6969 | -0.001 | -0.4346 | No |
| 8 | MMP10 | MMP10 Entrez, Source | matrix metallopeptidase 10 (stromelysin 2) | 8565 | -0.036 | -0.5462 | No |
| 9 | TIMP3 | TIMP3 Entrez, Source | TIMP metallopeptidase inhibitor 3 (Sorsby fundus dystrophy, pseudoinflammatory) | 11212 | -0.122 | -0.7175 | No |
| 10 | MMP16 | MMP16 Entrez, Source | matrix metallopeptidase 16 (membrane-inserted) | 11849 | -0.160 | -0.7295 | Yes |
| 11 | MMP9 | MMP9 Entrez, Source | matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase) | 12039 | -0.176 | -0.7042 | Yes |
| 12 | MMP14 | MMP14 Entrez, Source | matrix metallopeptidase 14 (membrane-inserted) | 12177 | -0.189 | -0.6723 | Yes |
| 13 | MMP24 | MMP24 Entrez, Source | matrix metallopeptidase 24 (membrane-inserted) | 13076 | -0.411 | -0.6479 | Yes |
| 14 | TIMP1 | TIMP1 Entrez, Source | TIMP metallopeptidase inhibitor 1 | 13213 | -0.582 | -0.5282 | Yes |
| 15 | TIMP2 | TIMP2 Entrez, Source | TIMP metallopeptidase inhibitor 2 | 13217 | -0.592 | -0.3963 | Yes |
| 16 | MMP11 | MMP11 Entrez, Source | matrix metallopeptidase 11 (stromelysin 3) | 13273 | -0.768 | -0.2290 | Yes |
| 17 | MMP2 | MMP2 Entrez, Source | matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase) | 13316 | -1.048 | 0.0020 | Yes |
