Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_single_gel_8d.class.cls #double_gel_8d_versus_single_gel_8d_repos |
| Phenotype | class.cls#double_gel_8d_versus_single_gel_8d_repos |
| Upregulated in class | double_gel_8d |
| GeneSet | MENSE_HYPOXIA_UP |
| Enrichment Score (ES) | 0.46745384 |
| Normalized Enrichment Score (NES) | 1.5640821 |
| Nominal p-value | 0.012903226 |
| FDR q-value | 0.086539306 |
| FWER p-Value | 1.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | INSIG1 | INSIG1 Entrez, Source | insulin induced gene 1 | 83 | 0.642 | 0.0475 | Yes |
| 2 | SCD | SCD Entrez, Source | stearoyl-CoA desaturase (delta-9-desaturase) | 84 | 0.641 | 0.1012 | Yes |
| 3 | PDK1 | PDK1 Entrez, Source | pyruvate dehydrogenase kinase, isozyme 1 | 143 | 0.545 | 0.1425 | Yes |
| 4 | PPP1R3C | PPP1R3C Entrez, Source | protein phosphatase 1, regulatory (inhibitor) subunit 3C | 146 | 0.543 | 0.1878 | Yes |
| 5 | MTAC2D1 | MTAC2D1 Entrez, Source | membrane targeting (tandem) C2 domain containing 1 | 224 | 0.456 | 0.2201 | Yes |
| 6 | BNIP3 | BNIP3 Entrez, Source | BCL2/adenovirus E1B 19kDa interacting protein 3 | 356 | 0.360 | 0.2404 | Yes |
| 7 | INSIG2 | INSIG2 Entrez, Source | insulin induced gene 2 | 364 | 0.356 | 0.2697 | Yes |
| 8 | GBE1 | GBE1 Entrez, Source | glucan (1,4-alpha-), branching enzyme 1 (glycogen branching enzyme, Andersen disease, glycogen storage disease type IV) | 368 | 0.355 | 0.2992 | Yes |
| 9 | SOD2 | SOD2 Entrez, Source | superoxide dismutase 2, mitochondrial | 391 | 0.343 | 0.3262 | Yes |
| 10 | BHLHB2 | BHLHB2 Entrez, Source | basic helix-loop-helix domain containing, class B, 2 | 581 | 0.272 | 0.3348 | Yes |
| 11 | VEGF | VEGF Entrez, Source | vascular endothelial growth factor | 585 | 0.271 | 0.3572 | Yes |
| 12 | CEBPB | CEBPB Entrez, Source | CCAAT/enhancer binding protein (C/EBP), beta | 862 | 0.212 | 0.3542 | Yes |
| 13 | NADSYN1 | NADSYN1 Entrez, Source | NAD synthetase 1 | 959 | 0.199 | 0.3636 | Yes |
| 14 | STC2 | STC2 Entrez, Source | stanniocalcin 2 | 1024 | 0.190 | 0.3747 | Yes |
| 15 | ALDOC | ALDOC Entrez, Source | aldolase C, fructose-bisphosphate | 1047 | 0.187 | 0.3887 | Yes |
| 16 | ADFP | ADFP Entrez, Source | adipose differentiation-related protein | 1069 | 0.185 | 0.4026 | Yes |
| 17 | PTDSR | PTDSR Entrez, Source | phosphatidylserine receptor | 1255 | 0.167 | 0.4027 | Yes |
| 18 | NFIL3 | NFIL3 Entrez, Source | nuclear factor, interleukin 3 regulated | 1319 | 0.163 | 0.4116 | Yes |
| 19 | PPFIA4 | PPFIA4 Entrez, Source | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4 | 1400 | 0.157 | 0.4187 | Yes |
| 20 | ATF3 | ATF3 Entrez, Source | activating transcription factor 3 | 1414 | 0.156 | 0.4308 | Yes |
| 21 | ERO1L | ERO1L Entrez, Source | ERO1-like (S. cerevisiae) | 1489 | 0.150 | 0.4378 | Yes |
| 22 | PBEF1 | PBEF1 Entrez, Source | pre-B-cell colony enhancing factor 1 | 1558 | 0.145 | 0.4448 | Yes |
| 23 | RAB40C | RAB40C Entrez, Source | RAB40C, member RAS oncogene family | 1677 | 0.138 | 0.4475 | Yes |
| 24 | EGLN1 | EGLN1 Entrez, Source | egl nine homolog 1 (C. elegans) | 1704 | 0.137 | 0.4570 | Yes |
| 25 | PFKFB4 | PFKFB4 Entrez, Source | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | 1761 | 0.133 | 0.4640 | Yes |
| 26 | GOSR2 | GOSR2 Entrez, Source | golgi SNAP receptor complex member 2 | 1858 | 0.128 | 0.4675 | Yes |
| 27 | ELL2 | ELL2 Entrez, Source | elongation factor, RNA polymerase II, 2 | 2214 | 0.114 | 0.4503 | No |
| 28 | ENO2 | ENO2 Entrez, Source | enolase 2 (gamma, neuronal) | 2627 | 0.098 | 0.4275 | No |
| 29 | PGK1 | PGK1 Entrez, Source | phosphoglycerate kinase 1 | 3566 | 0.069 | 0.3627 | No |
| 30 | GPI | GPI Entrez, Source | glucose phosphate isomerase | 3857 | 0.063 | 0.3461 | No |
| 31 | ABCB6 | ABCB6 Entrez, Source | ATP-binding cassette, sub-family B (MDR/TAP), member 6 | 3958 | 0.061 | 0.3436 | No |
| 32 | BNIP3L | BNIP3L Entrez, Source | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 4011 | 0.059 | 0.3447 | No |
| 33 | CEBPD | CEBPD Entrez, Source | CCAAT/enhancer binding protein (C/EBP), delta | 4687 | 0.044 | 0.2976 | No |
| 34 | CLPB | CLPB Entrez, Source | ClpB caseinolytic peptidase B homolog (E. coli) | 4844 | 0.041 | 0.2893 | No |
| 35 | SLC6A6 | SLC6A6 Entrez, Source | solute carrier family 6 (neurotransmitter transporter, taurine), member 6 | 4874 | 0.040 | 0.2905 | No |
| 36 | ANGPTL4 | ANGPTL4 Entrez, Source | angiopoietin-like 4 | 5417 | 0.030 | 0.2522 | No |
| 37 | PFKFB3 | PFKFB3 Entrez, Source | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 | 6145 | 0.015 | 0.1987 | No |
| 38 | SLC2A3 | SLC2A3 Entrez, Source | solute carrier family 2 (facilitated glucose transporter), member 3 | 6683 | 0.004 | 0.1587 | No |
| 39 | HK2 | HK2 Entrez, Source | hexokinase 2 | 6922 | -0.000 | 0.1408 | No |
| 40 | KLF4 | KLF4 Entrez, Source | Kruppel-like factor 4 (gut) | 7004 | -0.002 | 0.1349 | No |
| 41 | PPP3CA | PPP3CA Entrez, Source | protein phosphatase 3 (formerly 2B), catalytic subunit, alpha isoform (calcineurin A alpha) | 7108 | -0.004 | 0.1275 | No |
| 42 | NOL3 | NOL3 Entrez, Source | nucleolar protein 3 (apoptosis repressor with CARD domain) | 7231 | -0.007 | 0.1189 | No |
| 43 | WSB1 | WSB1 Entrez, Source | WD repeat and SOCS box-containing 1 | 7573 | -0.014 | 0.0944 | No |
| 44 | HCFC1R1 | HCFC1R1 Entrez, Source | host cell factor C1 regulator 1 (XPO1 dependent) | 7795 | -0.019 | 0.0793 | No |
| 45 | WDR5B | WDR5B Entrez, Source | WD repeat domain 5B | 7988 | -0.023 | 0.0668 | No |
| 46 | CLK3 | CLK3 Entrez, Source | CDC-like kinase 3 | 8705 | -0.039 | 0.0162 | No |
| 47 | GADD45A | GADD45A Entrez, Source | growth arrest and DNA-damage-inducible, alpha | 9083 | -0.048 | -0.0082 | No |
| 48 | PRPSAP1 | PRPSAP1 Entrez, Source | phosphoribosyl pyrophosphate synthetase-associated protein 1 | 9492 | -0.060 | -0.0339 | No |
| 49 | SPAG4 | SPAG4 Entrez, Source | sperm associated antigen 4 | 10309 | -0.085 | -0.0882 | No |
| 50 | MXI1 | MXI1 Entrez, Source | MAX interactor 1 | 10722 | -0.099 | -0.1109 | No |
| 51 | CTTN | CTTN Entrez, Source | cortactin | 10911 | -0.107 | -0.1161 | No |
| 52 | P4HA1 | P4HA1 Entrez, Source | procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha polypeptide I | 11102 | -0.117 | -0.1206 | No |
| 53 | RNASE4 | RNASE4 Entrez, Source | ribonuclease, RNase A family, 4 | 12272 | -0.201 | -0.1918 | No |
| 54 | KLHL24 | KLHL24 Entrez, Source | kelch-like 24 (Drosophila) | 12386 | -0.213 | -0.1824 | No |
| 55 | ADM | ADM Entrez, Source | adrenomedullin | 12796 | -0.285 | -0.1894 | No |
| 56 | NDRG1 | NDRG1 Entrez, Source | N-myc downstream regulated gene 1 | 13282 | -0.795 | -0.1593 | No |
| 57 | BHLHB3 | BHLHB3 Entrez, Source | basic helix-loop-helix domain containing, class B, 3 | 13305 | -0.964 | -0.0803 | No |
| 58 | LOX | LOX Entrez, Source | lysyl oxidase | 13308 | -0.991 | 0.0026 | No |
