Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_single_gel_8d.class.cls #double_gel_8d_versus_single_gel_8d_repos |
| Phenotype | class.cls#double_gel_8d_versus_single_gel_8d_repos |
| Upregulated in class | double_gel_8d |
| GeneSet | MONOOXYGENASE_ACTIVITY |
| Enrichment Score (ES) | 0.84853035 |
| Normalized Enrichment Score (NES) | 2.192383 |
| Nominal p-value | 0.0 |
| FDR q-value | 7.120228E-5 |
| FWER p-Value | 0.0030 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | CYP17A1 | CYP17A1 Entrez, Source | cytochrome P450, family 17, subfamily A, polypeptide 1 | 1 | 1.475 | 0.3016 | Yes |
| 2 | CYP8B1 | CYP8B1 Entrez, Source | cytochrome P450, family 8, subfamily B, polypeptide 1 | 14 | 1.030 | 0.5113 | Yes |
| 3 | KMO | KMO Entrez, Source | kynurenine 3-monooxygenase (kynurenine 3-hydroxylase) | 174 | 0.497 | 0.6011 | Yes |
| 4 | SC4MOL | SC4MOL Entrez, Source | sterol-C4-methyl oxidase-like | 284 | 0.409 | 0.6766 | Yes |
| 5 | CYP4F2 | CYP4F2 Entrez, Source | cytochrome P450, family 4, subfamily F, polypeptide 2 | 403 | 0.337 | 0.7367 | Yes |
| 6 | PAH | PAH Entrez, Source | phenylalanine hydroxylase | 411 | 0.336 | 0.8049 | Yes |
| 7 | CYP27A1 | CYP27A1 Entrez, Source | cytochrome P450, family 27, subfamily A, polypeptide 1 | 578 | 0.274 | 0.8485 | Yes |
| 8 | NOS3 | NOS3 Entrez, Source | nitric oxide synthase 3 (endothelial cell) | 1840 | 0.129 | 0.7803 | No |
| 9 | CYP19A1 | CYP19A1 Entrez, Source | cytochrome P450, family 19, subfamily A, polypeptide 1 | 2909 | 0.088 | 0.7181 | No |
| 10 | FMO2 | FMO2 Entrez, Source | flavin containing monooxygenase 2 (non-functional) | 4078 | 0.058 | 0.6423 | No |
| 11 | NOS1 | NOS1 Entrez, Source | nitric oxide synthase 1 (neuronal) | 4800 | 0.042 | 0.5967 | No |
| 12 | CYP26A1 | CYP26A1 Entrez, Source | cytochrome P450, family 26, subfamily A, polypeptide 1 | 5664 | 0.024 | 0.5369 | No |
| 13 | CYP3A4 | CYP3A4 Entrez, Source | cytochrome P450, family 3, subfamily A, polypeptide 4 | 5860 | 0.021 | 0.5266 | No |
| 14 | CYP7B1 | CYP7B1 Entrez, Source | cytochrome P450, family 7, subfamily B, polypeptide 1 | 7432 | -0.011 | 0.4109 | No |
| 15 | TH | TH Entrez, Source | tyrosine hydroxylase | 7455 | -0.011 | 0.4116 | No |
| 16 | CYP11B1 | CYP11B1 Entrez, Source | cytochrome P450, family 11, subfamily B, polypeptide 1 | 7700 | -0.017 | 0.3967 | No |
| 17 | FMO1 | FMO1 Entrez, Source | flavin containing monooxygenase 1 | 7782 | -0.018 | 0.3943 | No |
| 18 | CYP1B1 | CYP1B1 Entrez, Source | cytochrome P450, family 1, subfamily B, polypeptide 1 | 11000 | -0.112 | 0.1758 | No |
