Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_single_gel_8d.class.cls #double_gel_8d_versus_single_gel_8d_repos |
| Phenotype | class.cls#double_gel_8d_versus_single_gel_8d_repos |
| Upregulated in class | single_gel_8d |
| GeneSet | MRNA_PROCESSING |
| Enrichment Score (ES) | -0.6305295 |
| Normalized Enrichment Score (NES) | -1.7025584 |
| Nominal p-value | 0.013671875 |
| FDR q-value | 0.07573053 |
| FWER p-Value | 1.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | SPOP | SPOP Entrez, Source | speckle-type POZ protein | 4316 | 0.052 | -0.2999 | No |
| 2 | SFRS8 | SFRS8 Entrez, Source | splicing factor, arginine/serine-rich 8 (suppressor-of-white-apricot homolog, Drosophila) | 4616 | 0.046 | -0.3012 | No |
| 3 | SFRS2 | SFRS2 Entrez, Source | splicing factor, arginine/serine-rich 2 | 5597 | 0.026 | -0.3629 | No |
| 4 | SFRS5 | SFRS5 Entrez, Source | splicing factor, arginine/serine-rich 5 | 7071 | -0.004 | -0.4719 | No |
| 5 | SIP1 | SIP1 Entrez, Source | survival of motor neuron protein interacting protein 1 | 7085 | -0.004 | -0.4711 | No |
| 6 | SMNDC1 | SMNDC1 Entrez, Source | survival motor neuron domain containing 1 | 8217 | -0.028 | -0.5432 | No |
| 7 | SFRS7 | SFRS7 Entrez, Source | splicing factor, arginine/serine-rich 7, 35kDa | 8464 | -0.033 | -0.5462 | No |
| 8 | U2AF2 | U2AF2 Entrez, Source | U2 small nuclear RNA auxiliary factor 2 | 9141 | -0.050 | -0.5741 | No |
| 9 | FUSIP1 | FUSIP1 Entrez, Source | FUS interacting protein (serine/arginine-rich) 1 | 9540 | -0.061 | -0.5759 | No |
| 10 | SFRS10 | SFRS10 Entrez, Source | splicing factor, arginine/serine-rich 10 (transformer 2 homolog, Drosophila) | 9695 | -0.065 | -0.5575 | No |
| 11 | CUGBP1 | CUGBP1 Entrez, Source | CUG triplet repeat, RNA binding protein 1 | 9815 | -0.069 | -0.5347 | No |
| 12 | SFRS9 | SFRS9 Entrez, Source | splicing factor, arginine/serine-rich 9 | 11092 | -0.116 | -0.5770 | Yes |
| 13 | SLU7 | SLU7 Entrez, Source | - | 11234 | -0.123 | -0.5308 | Yes |
| 14 | SFPQ | SFPQ Entrez, Source | splicing factor proline/glutamine-rich (polypyrimidine tract binding protein associated) | 11277 | -0.125 | -0.4762 | Yes |
| 15 | HNRPR | HNRPR Entrez, Source | heterogeneous nuclear ribonucleoprotein R | 11314 | -0.127 | -0.4203 | Yes |
| 16 | PRPF8 | PRPF8 Entrez, Source | PRP8 pre-mRNA processing factor 8 homolog (S. cerevisiae) | 11379 | -0.130 | -0.3654 | Yes |
| 17 | SF3A3 | SF3A3 Entrez, Source | splicing factor 3a, subunit 3, 60kDa | 11660 | -0.148 | -0.3184 | Yes |
| 18 | PTBP1 | PTBP1 Entrez, Source | polypyrimidine tract binding protein 1 | 11675 | -0.148 | -0.2511 | Yes |
| 19 | HNRPA1 | HNRPA1 Entrez, Source | heterogeneous nuclear ribonucleoprotein A1 | 11811 | -0.158 | -0.1887 | Yes |
| 20 | KHSRP | KHSRP Entrez, Source | KH-type splicing regulatory protein (FUSE binding protein 2) | 11984 | -0.171 | -0.1226 | Yes |
| 21 | KHDRBS1 | KHDRBS1 Entrez, Source | KH domain containing, RNA binding, signal transduction associated 1 | 12056 | -0.178 | -0.0461 | Yes |
| 22 | SF3B4 | SF3B4 Entrez, Source | splicing factor 3b, subunit 4, 49kDa | 12871 | -0.309 | 0.0354 | Yes |
