Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_single_gel_8d.class.cls #double_gel_8d_versus_single_gel_8d_repos |
| Phenotype | class.cls#double_gel_8d_versus_single_gel_8d_repos |
| Upregulated in class | single_gel_8d |
| GeneSet | MYOD_NIH3T3_UP |
| Enrichment Score (ES) | -0.5365726 |
| Normalized Enrichment Score (NES) | -1.7395418 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.06553807 |
| FWER p-Value | 0.997 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | TFRC | TFRC Entrez, Source | transferrin receptor (p90, CD71) | 311 | 0.390 | 0.0128 | No |
| 2 | HMGCS2 | HMGCS2 Entrez, Source | 3-hydroxy-3-methylglutaryl-Coenzyme A synthase 2 (mitochondrial) | 360 | 0.358 | 0.0425 | No |
| 3 | VKORC1 | VKORC1 Entrez, Source | vitamin K epoxide reductase complex, subunit 1 | 371 | 0.354 | 0.0747 | No |
| 4 | MYBPH | MYBPH Entrez, Source | myosin binding protein H | 919 | 0.204 | 0.0525 | No |
| 5 | PPFIA4 | PPFIA4 Entrez, Source | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4 | 1400 | 0.157 | 0.0309 | No |
| 6 | HSPB8 | HSPB8 Entrez, Source | heat shock 22kDa protein 8 | 1968 | 0.123 | -0.0003 | No |
| 7 | TNNT3 | TNNT3 Entrez, Source | troponin T type 3 (skeletal, fast) | 2118 | 0.117 | -0.0007 | No |
| 8 | IGFBP5 | IGFBP5 Entrez, Source | insulin-like growth factor binding protein 5 | 2222 | 0.114 | 0.0021 | No |
| 9 | HRC | HRC Entrez, Source | histidine rich calcium binding protein | 2275 | 0.111 | 0.0086 | No |
| 10 | RB1 | RB1 Entrez, Source | retinoblastoma 1 (including osteosarcoma) | 2307 | 0.110 | 0.0164 | No |
| 11 | AKT2 | AKT2 Entrez, Source | v-akt murine thymoma viral oncogene homolog 2 | 2581 | 0.100 | 0.0052 | No |
| 12 | ATP2A1 | ATP2A1 Entrez, Source | ATPase, Ca++ transporting, cardiac muscle, fast twitch 1 | 2970 | 0.086 | -0.0160 | No |
| 13 | TNNI2 | TNNI2 Entrez, Source | troponin I type 2 (skeletal, fast) | 3007 | 0.085 | -0.0109 | No |
| 14 | MYH3 | MYH3 Entrez, Source | myosin, heavy chain 3, skeletal muscle, embryonic | 3820 | 0.064 | -0.0661 | No |
| 15 | RHOB | RHOB Entrez, Source | ras homolog gene family, member B | 3872 | 0.063 | -0.0641 | No |
| 16 | CD82 | CD82 Entrez, Source | CD82 molecule | 3908 | 0.062 | -0.0610 | No |
| 17 | MYOD1 | MYOD1 Entrez, Source | myogenic differentiation 1 | 4224 | 0.054 | -0.0797 | No |
| 18 | TNNT2 | TNNT2 Entrez, Source | troponin T type 2 (cardiac) | 4572 | 0.047 | -0.1014 | No |
| 19 | CHRNG | CHRNG Entrez, Source | cholinergic receptor, nicotinic, gamma | 4852 | 0.041 | -0.1186 | No |
| 20 | MYOG | MYOG Entrez, Source | myogenin (myogenic factor 4) | 5333 | 0.031 | -0.1518 | No |
| 21 | ENO3 | ENO3 Entrez, Source | enolase 3 (beta, muscle) | 6027 | 0.018 | -0.2023 | No |
| 22 | PDLIM3 | PDLIM3 Entrez, Source | PDZ and LIM domain 3 | 7355 | -0.009 | -0.3013 | No |
| 23 | CHRNA1 | CHRNA1 Entrez, Source | cholinergic receptor, nicotinic, alpha 1 (muscle) | 7663 | -0.016 | -0.3229 | No |
| 24 | CCND3 | CCND3 Entrez, Source | cyclin D3 | 7859 | -0.020 | -0.3357 | No |
| 25 | NAV2 | NAV2 Entrez, Source | neuron navigator 2 | 8365 | -0.032 | -0.3708 | No |
| 26 | STK17B | STK17B Entrez, Source | serine/threonine kinase 17b (apoptosis-inducing) | 9039 | -0.047 | -0.4171 | No |
| 27 | HIP1 | HIP1 Entrez, Source | huntingtin interacting protein 1 | 9098 | -0.049 | -0.4169 | No |
| 28 | ATP1A1 | ATP1A1 Entrez, Source | ATPase, Na+/K+ transporting, alpha 1 polypeptide | 9325 | -0.055 | -0.4288 | No |
| 29 | PVR | PVR Entrez, Source | poliovirus receptor | 9590 | -0.062 | -0.4429 | No |
| 30 | CUGBP1 | CUGBP1 Entrez, Source | CUG triplet repeat, RNA binding protein 1 | 9815 | -0.069 | -0.4534 | No |
| 31 | GADD45G | GADD45G Entrez, Source | growth arrest and DNA-damage-inducible, gamma | 10034 | -0.076 | -0.4627 | No |
| 32 | CKM | CKM Entrez, Source | creatine kinase, muscle | 10056 | -0.076 | -0.4572 | No |
| 33 | HES6 | HES6 Entrez, Source | hairy and enhancer of split 6 (Drosophila) | 10168 | -0.080 | -0.4581 | No |
| 34 | ANXA11 | ANXA11 Entrez, Source | annexin A11 | 10207 | -0.082 | -0.4534 | No |
| 35 | LRP4 | LRP4 Entrez, Source | low density lipoprotein receptor-related protein 4 | 10260 | -0.083 | -0.4496 | No |
| 36 | PSMC3 | PSMC3 Entrez, Source | proteasome (prosome, macropain) 26S subunit, ATPase, 3 | 10989 | -0.111 | -0.4940 | No |
| 37 | KLHL5 | KLHL5 Entrez, Source | kelch-like 5 (Drosophila) | 11028 | -0.113 | -0.4864 | No |
| 38 | CHRNB1 | CHRNB1 Entrez, Source | cholinergic receptor, nicotinic, beta 1 (muscle) | 11696 | -0.149 | -0.5227 | Yes |
| 39 | DCAKD | DCAKD Entrez, Source | dephospho-CoA kinase domain containing | 11750 | -0.152 | -0.5125 | Yes |
| 40 | KLF5 | KLF5 Entrez, Source | Kruppel-like factor 5 (intestinal) | 11774 | -0.155 | -0.4999 | Yes |
| 41 | CCDC23 | CCDC23 Entrez, Source | coiled-coil domain containing 23 | 11828 | -0.159 | -0.4891 | Yes |
| 42 | KIFC3 | KIFC3 Entrez, Source | kinesin family member C3 | 11973 | -0.171 | -0.4841 | Yes |
| 43 | CDKN1A | CDKN1A Entrez, Source | cyclin-dependent kinase inhibitor 1A (p21, Cip1) | 12163 | -0.188 | -0.4808 | Yes |
| 44 | HS2ST1 | HS2ST1 Entrez, Source | heparan sulfate 2-O-sulfotransferase 1 | 12421 | -0.218 | -0.4799 | Yes |
| 45 | BIN1 | BIN1 Entrez, Source | bridging integrator 1 | 12429 | -0.219 | -0.4601 | Yes |
| 46 | PBXIP1 | PBXIP1 Entrez, Source | pre-B-cell leukemia transcription factor interacting protein 1 | 12721 | -0.269 | -0.4570 | Yes |
| 47 | SCHIP1 | SCHIP1 Entrez, Source | schwannomin interacting protein 1 | 12910 | -0.326 | -0.4409 | Yes |
| 48 | RUNX1 | RUNX1 Entrez, Source | runt-related transcription factor 1 (acute myeloid leukemia 1; aml1 oncogene) | 12949 | -0.338 | -0.4123 | Yes |
| 49 | PRKAR2B | PRKAR2B Entrez, Source | protein kinase, cAMP-dependent, regulatory, type II, beta | 13002 | -0.366 | -0.3822 | Yes |
| 50 | GPC1 | GPC1 Entrez, Source | glypican 1 | 13081 | -0.412 | -0.3497 | Yes |
| 51 | PRSS23 | PRSS23 Entrez, Source | protease, serine, 23 | 13122 | -0.445 | -0.3114 | Yes |
| 52 | PRND | PRND Entrez, Source | prion protein 2 (dublet) | 13295 | -0.892 | -0.2415 | Yes |
| 53 | DBN1 | DBN1 Entrez, Source | drebrin 1 | 13319 | -1.054 | -0.1453 | Yes |
| 54 | ACTA1 | ACTA1 Entrez, Source | actin, alpha 1, skeletal muscle | 13340 | -1.581 | 0.0002 | Yes |
