Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_single_gel_8d.class.cls #double_gel_8d_versus_single_gel_8d_repos |
| Phenotype | class.cls#double_gel_8d_versus_single_gel_8d_repos |
| Upregulated in class | double_gel_8d |
| GeneSet | NADLER_OBESITY_DN |
| Enrichment Score (ES) | 0.5679938 |
| Normalized Enrichment Score (NES) | 1.6959587 |
| Nominal p-value | 0.0112866815 |
| FDR q-value | 0.033933017 |
| FWER p-Value | 0.999 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | THRSP | THRSP Entrez, Source | thyroid hormone responsive (SPOT14 homolog, rat) | 63 | 0.711 | 0.1115 | Yes |
| 2 | PCK1 | PCK1 Entrez, Source | phosphoenolpyruvate carboxykinase 1 (soluble) | 167 | 0.505 | 0.1864 | Yes |
| 3 | FDFT1 | FDFT1 Entrez, Source | farnesyl-diphosphate farnesyltransferase 1 | 194 | 0.481 | 0.2632 | Yes |
| 4 | RBP4 | RBP4 Entrez, Source | retinol binding protein 4, plasma | 351 | 0.361 | 0.3106 | Yes |
| 5 | GBE1 | GBE1 Entrez, Source | glucan (1,4-alpha-), branching enzyme 1 (glycogen branching enzyme, Andersen disease, glycogen storage disease type IV) | 368 | 0.355 | 0.3675 | Yes |
| 6 | SREBF1 | SREBF1 Entrez, Source | sterol regulatory element binding transcription factor 1 | 467 | 0.313 | 0.4114 | Yes |
| 7 | AGT | AGT Entrez, Source | angiotensinogen (serpin peptidase inhibitor, clade A, member 8) | 514 | 0.295 | 0.4562 | Yes |
| 8 | DDT | DDT Entrez, Source | D-dopachrome tautomerase | 583 | 0.271 | 0.4955 | Yes |
| 9 | FABP4 | FABP4 Entrez, Source | fatty acid binding protein 4, adipocyte | 947 | 0.200 | 0.5009 | Yes |
| 10 | DBI | DBI Entrez, Source | diazepam binding inhibitor (GABA receptor modulator, acyl-Coenzyme A binding protein) | 1077 | 0.184 | 0.5214 | Yes |
| 11 | TSHR | TSHR Entrez, Source | thyroid stimulating hormone receptor | 1351 | 0.160 | 0.5271 | Yes |
| 12 | RASD1 | RASD1 Entrez, Source | RAS, dexamethasone-induced 1 | 1396 | 0.157 | 0.5496 | Yes |
| 13 | HP | HP Entrez, Source | haptoglobin | 1480 | 0.151 | 0.5680 | Yes |
| 14 | GSTA3 | GSTA3 Entrez, Source | glutathione S-transferase A3 | 2058 | 0.119 | 0.5441 | No |
| 15 | ASNS | ASNS Entrez, Source | asparagine synthetase | 2424 | 0.106 | 0.5340 | No |
| 16 | COX8A | COX8A Entrez, Source | cytochrome c oxidase subunit 8A (ubiquitous) | 2501 | 0.102 | 0.5450 | No |
| 17 | GPD2 | GPD2 Entrez, Source | glycerol-3-phosphate dehydrogenase 2 (mitochondrial) | 2771 | 0.093 | 0.5400 | No |
| 18 | CFD | CFD Entrez, Source | complement factor D (adipsin) | 4814 | 0.042 | 0.3934 | No |
| 19 | APOE | APOE Entrez, Source | apolipoprotein E | 5056 | 0.037 | 0.3813 | No |
| 20 | ADRB3 | ADRB3 Entrez, Source | adrenergic, beta-3-, receptor | 5857 | 0.021 | 0.3246 | No |
| 21 | ALDH2 | ALDH2 Entrez, Source | aldehyde dehydrogenase 2 family (mitochondrial) | 6279 | 0.012 | 0.2950 | No |
| 22 | FMO1 | FMO1 Entrez, Source | flavin containing monooxygenase 1 | 7782 | -0.018 | 0.1851 | No |
| 23 | SOD1 | SOD1 Entrez, Source | superoxide dismutase 1, soluble (amyotrophic lateral sclerosis 1 (adult)) | 7856 | -0.020 | 0.1829 | No |
| 24 | EEF1A1 | EEF1A1 Entrez, Source | eukaryotic translation elongation factor 1 alpha 1 | 7913 | -0.021 | 0.1822 | No |
| 25 | BCAT2 | BCAT2 Entrez, Source | branched chain aminotransferase 2, mitochondrial | 8232 | -0.028 | 0.1629 | No |
| 26 | CDKN2C | CDKN2C Entrez, Source | cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) | 8322 | -0.030 | 0.1612 | No |
| 27 | B2M | B2M Entrez, Source | beta-2-microglobulin | 8650 | -0.038 | 0.1428 | No |
| 28 | ALDOA | ALDOA Entrez, Source | aldolase A, fructose-bisphosphate | 9745 | -0.066 | 0.0715 | No |
| 29 | UBB | UBB Entrez, Source | ubiquitin B | 10179 | -0.081 | 0.0521 | No |
| 30 | LDHB | LDHB Entrez, Source | lactate dehydrogenase B | 10723 | -0.099 | 0.0276 | No |
| 31 | C2 | C2 Entrez, Source | complement component 2 | 11264 | -0.125 | 0.0074 | No |
| 32 | RBMS2 | RBMS2 Entrez, Source | RNA binding motif, single stranded interacting protein 2 | 12453 | -0.221 | -0.0458 | No |
| 33 | PYGB | PYGB Entrez, Source | phosphorylase, glycogen; brain | 12849 | -0.302 | -0.0260 | No |
| 34 | NNAT | NNAT Entrez, Source | neuronatin | 13037 | -0.385 | 0.0229 | No |
