Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_single_gel_8d.class.cls #double_gel_8d_versus_single_gel_8d_repos |
| Phenotype | class.cls#double_gel_8d_versus_single_gel_8d_repos |
| Upregulated in class | double_gel_8d |
| GeneSet | NITROGEN_COMPOUND_CATABOLIC_PROCESS |
| Enrichment Score (ES) | 0.6532614 |
| Normalized Enrichment Score (NES) | 1.8236068 |
| Nominal p-value | 0.0020491802 |
| FDR q-value | 0.011227335 |
| FWER p-Value | 0.814 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | HGD | HGD Entrez, Source | homogentisate 1,2-dioxygenase (homogentisate oxidase) | 17 | 0.930 | 0.1414 | Yes |
| 2 | GOT1 | GOT1 Entrez, Source | glutamic-oxaloacetic transaminase 1, soluble (aspartate aminotransferase 1) | 56 | 0.731 | 0.2507 | Yes |
| 3 | ASL | ASL Entrez, Source | argininosuccinate lyase | 122 | 0.586 | 0.3358 | Yes |
| 4 | ARG1 | ARG1 Entrez, Source | arginase, liver | 246 | 0.438 | 0.3937 | Yes |
| 5 | BCKDHB | BCKDHB Entrez, Source | branched chain keto acid dehydrogenase E1, beta polypeptide (maple syrup urine disease) | 271 | 0.419 | 0.4563 | Yes |
| 6 | FAH | FAH Entrez, Source | fumarylacetoacetate hydrolase (fumarylacetoacetase) | 277 | 0.416 | 0.5198 | Yes |
| 7 | BCKDHA | BCKDHA Entrez, Source | branched chain keto acid dehydrogenase E1, alpha polypeptide | 389 | 0.344 | 0.5643 | Yes |
| 8 | COLQ | COLQ Entrez, Source | collagen-like tail subunit (single strand of homotrimer) of asymmetric acetylcholinesterase | 646 | 0.252 | 0.5838 | Yes |
| 9 | TST | TST Entrez, Source | thiosulfate sulfurtransferase (rhodanese) | 926 | 0.203 | 0.5940 | Yes |
| 10 | ASPA | ASPA Entrez, Source | aspartoacylase (Canavan disease) | 1027 | 0.189 | 0.6156 | Yes |
| 11 | GCSH | GCSH Entrez, Source | glycine cleavage system protein H (aminomethyl carrier) | 1046 | 0.187 | 0.6430 | Yes |
| 12 | HPD | HPD Entrez, Source | 4-hydroxyphenylpyruvate dioxygenase | 1252 | 0.167 | 0.6533 | Yes |
| 13 | GLUD1 | GLUD1 Entrez, Source | glutamate dehydrogenase 1 | 1864 | 0.128 | 0.6270 | No |
| 14 | ASRGL1 | ASRGL1 Entrez, Source | asparaginase like 1 | 2968 | 0.086 | 0.5574 | No |
| 15 | BCKDK | BCKDK Entrez, Source | branched chain ketoacid dehydrogenase kinase | 3082 | 0.082 | 0.5615 | No |
| 16 | AMT | AMT Entrez, Source | aminomethyltransferase | 3875 | 0.063 | 0.5116 | No |
| 17 | MPST | MPST Entrez, Source | mercaptopyruvate sulfurtransferase | 4713 | 0.044 | 0.4555 | No |
| 18 | GAD1 | GAD1 Entrez, Source | glutamate decarboxylase 1 (brain, 67kDa) | 5183 | 0.034 | 0.4255 | No |
| 19 | MCCC2 | MCCC2 Entrez, Source | methylcrotonoyl-Coenzyme A carboxylase 2 (beta) | 6381 | 0.010 | 0.3372 | No |
| 20 | GOT2 | GOT2 Entrez, Source | glutamic-oxaloacetic transaminase 2, mitochondrial (aspartate aminotransferase 2) | 7234 | -0.007 | 0.2743 | No |
| 21 | DHPS | DHPS Entrez, Source | deoxyhypusine synthase | 7692 | -0.016 | 0.2425 | No |
| 22 | INDO | INDO Entrez, Source | indoleamine-pyrrole 2,3 dioxygenase | 8124 | -0.026 | 0.2141 | No |
| 23 | GAD2 | GAD2 Entrez, Source | glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa) | 9551 | -0.061 | 0.1164 | No |
| 24 | DDAH1 | DDAH1 Entrez, Source | dimethylarginine dimethylaminohydrolase 1 | 12983 | -0.354 | -0.0868 | No |
| 25 | DDAH2 | DDAH2 Entrez, Source | dimethylarginine dimethylaminohydrolase 2 | 13266 | -0.741 | 0.0057 | No |
