Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_single_gel_8d.class.cls #double_gel_8d_versus_single_gel_8d_repos |
| Phenotype | class.cls#double_gel_8d_versus_single_gel_8d_repos |
| Upregulated in class | double_gel_8d |
| GeneSet | NUCLEAR_RECEPTORS |
| Enrichment Score (ES) | 0.65815306 |
| Normalized Enrichment Score (NES) | 1.9640632 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.002584406 |
| FWER p-Value | 0.213 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | NR1I3 | NR1I3 Entrez, Source | nuclear receptor subfamily 1, group I, member 3 | 47 | 0.769 | 0.1541 | Yes |
| 2 | RARB | RARB Entrez, Source | retinoic acid receptor, beta | 101 | 0.614 | 0.2761 | Yes |
| 3 | NR5A2 | NR5A2 Entrez, Source | nuclear receptor subfamily 5, group A, member 2 | 220 | 0.457 | 0.3608 | Yes |
| 4 | RXRA | RXRA Entrez, Source | retinoid X receptor, alpha | 375 | 0.353 | 0.4216 | Yes |
| 5 | RXRG | RXRG Entrez, Source | retinoid X receptor, gamma | 490 | 0.304 | 0.4754 | Yes |
| 6 | NR1H3 | NR1H3 Entrez, Source | nuclear receptor subfamily 1, group H, member 3 | 540 | 0.287 | 0.5305 | Yes |
| 7 | NR1I2 | NR1I2 Entrez, Source | nuclear receptor subfamily 1, group I, member 2 | 613 | 0.262 | 0.5788 | Yes |
| 8 | PPARA | PPARA Entrez, Source | peroxisome proliferative activated receptor, alpha | 732 | 0.231 | 0.6173 | Yes |
| 9 | AR | AR Entrez, Source | androgen receptor (dihydrotestosterone receptor; testicular feminization; spinal and bulbar muscular atrophy; Kennedy disease) | 1135 | 0.178 | 0.6235 | Yes |
| 10 | ESR2 | ESR2 Entrez, Source | estrogen receptor 2 (ER beta) | 1837 | 0.129 | 0.5973 | Yes |
| 11 | THRB | THRB Entrez, Source | thyroid hormone receptor, beta (erythroblastic leukemia viral (v-erb-a) oncogene homolog 2, avian) | 2013 | 0.121 | 0.6090 | Yes |
| 12 | HNF4A | HNF4A Entrez, Source | hepatocyte nuclear factor 4, alpha | 2205 | 0.114 | 0.6180 | Yes |
| 13 | NR2C2 | NR2C2 Entrez, Source | nuclear receptor subfamily 2, group C, member 2 | 2232 | 0.113 | 0.6393 | Yes |
| 14 | VDR | VDR Entrez, Source | vitamin D (1,25- dihydroxyvitamin D3) receptor | 2521 | 0.102 | 0.6385 | Yes |
| 15 | PPARG | PPARG Entrez, Source | peroxisome proliferative activated receptor, gamma | 2538 | 0.101 | 0.6582 | Yes |
| 16 | PPARD | PPARD Entrez, Source | peroxisome proliferative activated receptor, delta | 3231 | 0.078 | 0.6221 | No |
| 17 | NR0B1 | NR0B1 Entrez, Source | nuclear receptor subfamily 0, group B, member 1 | 4557 | 0.047 | 0.5322 | No |
| 18 | NR3C1 | NR3C1 Entrez, Source | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | 4791 | 0.042 | 0.5233 | No |
| 19 | ALK | ALK Entrez, Source | anaplastic lymphoma kinase (Ki-1) | 4930 | 0.039 | 0.5210 | No |
| 20 | PGR | PGR Entrez, Source | progesterone receptor | 5058 | 0.037 | 0.5190 | No |
| 21 | NR2F6 | NR2F6 Entrez, Source | nuclear receptor subfamily 2, group F, member 6 | 5110 | 0.036 | 0.5225 | No |
| 22 | THRA | THRA Entrez, Source | thyroid hormone receptor, alpha (erythroblastic leukemia viral (v-erb-a) oncogene homolog, avian) | 5968 | 0.019 | 0.4620 | No |
| 23 | ESRRA | ESRRA Entrez, Source | estrogen-related receptor alpha | 6502 | 0.008 | 0.4236 | No |
| 24 | NR4A1 | NR4A1 Entrez, Source | nuclear receptor subfamily 4, group A, member 1 | 6878 | 0.001 | 0.3956 | No |
| 25 | NR2F1 | NR2F1 Entrez, Source | nuclear receptor subfamily 2, group F, member 1 | 7183 | -0.006 | 0.3739 | No |
| 26 | NR1D2 | NR1D2 Entrez, Source | nuclear receptor subfamily 1, group D, member 2 | 7919 | -0.021 | 0.3231 | No |
| 27 | NPM1 | NPM1 Entrez, Source | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 8204 | -0.028 | 0.3074 | No |
| 28 | NR4A2 | NR4A2 Entrez, Source | nuclear receptor subfamily 4, group A, member 2 | 8301 | -0.030 | 0.3064 | No |
| 29 | ESR1 | ESR1 Entrez, Source | estrogen receptor 1 | 8446 | -0.033 | 0.3023 | No |
| 30 | RARA | RARA Entrez, Source | retinoic acid receptor, alpha | 9483 | -0.059 | 0.2366 | No |
| 31 | RXRB | RXRB Entrez, Source | retinoid X receptor, beta | 9739 | -0.066 | 0.2311 | No |
| 32 | NR2F2 | NR2F2 Entrez, Source | nuclear receptor subfamily 2, group F, member 2 | 10001 | -0.075 | 0.2268 | No |
| 33 | NR1H2 | NR1H2 Entrez, Source | nuclear receptor subfamily 1, group H, member 2 | 11118 | -0.118 | 0.1671 | No |
