Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_single_gel_8d.class.cls #double_gel_8d_versus_single_gel_8d_repos |
| Phenotype | class.cls#double_gel_8d_versus_single_gel_8d_repos |
| Upregulated in class | single_gel_8d |
| GeneSet | O6BG_RESIST_MEDULLOBLASTOMA_DN |
| Enrichment Score (ES) | -0.6043076 |
| Normalized Enrichment Score (NES) | -1.6834513 |
| Nominal p-value | 0.007889546 |
| FDR q-value | 0.080330834 |
| FWER p-Value | 1.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | YARS | YARS Entrez, Source | tyrosyl-tRNA synthetase | 1355 | 0.160 | -0.0647 | No |
| 2 | LRPPRC | LRPPRC Entrez, Source | leucine-rich PPR-motif containing | 2030 | 0.121 | -0.0875 | No |
| 3 | EPRS | EPRS Entrez, Source | glutamyl-prolyl-tRNA synthetase | 2170 | 0.115 | -0.0713 | No |
| 4 | ATRX | ATRX Entrez, Source | alpha thalassemia/mental retardation syndrome X-linked (RAD54 homolog, S. cerevisiae) | 2846 | 0.090 | -0.1013 | No |
| 5 | KDELR2 | KDELR2 Entrez, Source | KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2 | 3147 | 0.080 | -0.1053 | No |
| 6 | PTTG1IP | PTTG1IP Entrez, Source | pituitary tumor-transforming 1 interacting protein | 3230 | 0.078 | -0.0936 | No |
| 7 | MTRR | MTRR Entrez, Source | 5-methyltetrahydrofolate-homocysteine methyltransferase reductase | 3648 | 0.068 | -0.1093 | No |
| 8 | CXCR4 | CXCR4 Entrez, Source | chemokine (C-X-C motif) receptor 4 | 5204 | 0.034 | -0.2182 | No |
| 9 | SFRS2 | SFRS2 Entrez, Source | splicing factor, arginine/serine-rich 2 | 5597 | 0.026 | -0.2417 | No |
| 10 | TCEA1 | TCEA1 Entrez, Source | transcription elongation factor A (SII), 1 | 6329 | 0.011 | -0.2940 | No |
| 11 | CS | CS Entrez, Source | citrate synthase | 7513 | -0.013 | -0.3800 | No |
| 12 | MAP2K6 | MAP2K6 Entrez, Source | mitogen-activated protein kinase kinase 6 | 7666 | -0.016 | -0.3877 | No |
| 13 | PRPF4 | PRPF4 Entrez, Source | PRP4 pre-mRNA processing factor 4 homolog (yeast) | 7770 | -0.018 | -0.3913 | No |
| 14 | ATP2B2 | ATP2B2 Entrez, Source | ATPase, Ca++ transporting, plasma membrane 2 | 8228 | -0.028 | -0.4191 | No |
| 15 | H3F3B | H3F3B Entrez, Source | H3 histone, family 3B (H3.3B) | 10288 | -0.084 | -0.5543 | No |
| 16 | CCT5 | CCT5 Entrez, Source | chaperonin containing TCP1, subunit 5 (epsilon) | 10843 | -0.105 | -0.5718 | No |
| 17 | SFPQ | SFPQ Entrez, Source | splicing factor proline/glutamine-rich (polypyrimidine tract binding protein associated) | 11277 | -0.125 | -0.5754 | Yes |
| 18 | CSPG2 | CSPG2 Entrez, Source | chondroitin sulfate proteoglycan 2 (versican) | 11420 | -0.132 | -0.5556 | Yes |
| 19 | CCNG1 | CCNG1 Entrez, Source | cyclin G1 | 11744 | -0.152 | -0.5448 | Yes |
| 20 | KHSRP | KHSRP Entrez, Source | KH-type splicing regulatory protein (FUSE binding protein 2) | 11984 | -0.171 | -0.5232 | Yes |
| 21 | TRIM28 | TRIM28 Entrez, Source | tripartite motif-containing 28 | 12221 | -0.194 | -0.4961 | Yes |
| 22 | SMPDL3A | SMPDL3A Entrez, Source | sphingomyelin phosphodiesterase, acid-like 3A | 12339 | -0.209 | -0.4567 | Yes |
| 23 | OGT | OGT Entrez, Source | O-linked N-acetylglucosamine (GlcNAc) transferase (UDP-N-acetylglucosamine:polypeptide-N-acetylglucosaminyl transferase) | 12392 | -0.214 | -0.4114 | Yes |
| 24 | RENBP | RENBP Entrez, Source | renin binding protein | 12639 | -0.251 | -0.3718 | Yes |
| 25 | TUBB | TUBB Entrez, Source | tubulin, beta | 12961 | -0.344 | -0.3165 | Yes |
| 26 | TSPAN3 | TSPAN3 Entrez, Source | tetraspanin 3 | 13264 | -0.735 | -0.1697 | Yes |
| 27 | COL4A1 | COL4A1 Entrez, Source | collagen, type IV, alpha 1 | 13269 | -0.760 | 0.0055 | Yes |
