Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_single_gel_8d.class.cls #double_gel_8d_versus_single_gel_8d_repos |
| Phenotype | class.cls#double_gel_8d_versus_single_gel_8d_repos |
| Upregulated in class | double_gel_8d |
| GeneSet | ORGANELLE_INNER_MEMBRANE |
| Enrichment Score (ES) | 0.48988077 |
| Normalized Enrichment Score (NES) | 1.6073391 |
| Nominal p-value | 0.008298756 |
| FDR q-value | 0.066087395 |
| FWER p-Value | 1.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | SLC25A15 | SLC25A15 Entrez, Source | solute carrier family 25 (mitochondrial carrier; ornithine transporter) member 15 | 113 | 0.597 | 0.1029 | Yes |
| 2 | HSD3B1 | HSD3B1 Entrez, Source | hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 | 293 | 0.402 | 0.1644 | Yes |
| 3 | SLC25A22 | SLC25A22 Entrez, Source | solute carrier family 25 (mitochondrial carrier: glutamate), member 22 | 488 | 0.305 | 0.2066 | Yes |
| 4 | NDUFA1 | NDUFA1 Entrez, Source | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 1, 7.5kDa | 644 | 0.254 | 0.2423 | Yes |
| 5 | TIMM9 | TIMM9 Entrez, Source | translocase of inner mitochondrial membrane 9 homolog (yeast) | 828 | 0.216 | 0.2690 | Yes |
| 6 | ATP5G1 | ATP5G1 Entrez, Source | ATP synthase, H+ transporting, mitochondrial F0 complex, subunit C1 (subunit 9) | 878 | 0.210 | 0.3046 | Yes |
| 7 | SLC25A1 | SLC25A1 Entrez, Source | solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1 | 946 | 0.200 | 0.3369 | Yes |
| 8 | SDHD | SDHD Entrez, Source | succinate dehydrogenase complex, subunit D, integral membrane protein | 1404 | 0.157 | 0.3318 | Yes |
| 9 | TIMM10 | TIMM10 Entrez, Source | translocase of inner mitochondrial membrane 10 homolog (yeast) | 1491 | 0.150 | 0.3534 | Yes |
| 10 | NARF | NARF Entrez, Source | nuclear prelamin A recognition factor | 1605 | 0.143 | 0.3716 | Yes |
| 11 | UQCRB | UQCRB Entrez, Source | ubiquinol-cytochrome c reductase binding protein | 1880 | 0.127 | 0.3748 | Yes |
| 12 | COX6B2 | COX6B2 Entrez, Source | cytochrome c oxidase subunit VIb polypeptide 2 (testis) | 1903 | 0.126 | 0.3967 | Yes |
| 13 | ALAS2 | ALAS2 Entrez, Source | aminolevulinate, delta-, synthase 2 (sideroblastic/hypochromic anemia) | 2203 | 0.114 | 0.3955 | Yes |
| 14 | BCS1L | BCS1L Entrez, Source | BCS1-like (yeast) | 2272 | 0.111 | 0.4112 | Yes |
| 15 | ATP5E | ATP5E Entrez, Source | ATP synthase, H+ transporting, mitochondrial F1 complex, epsilon subunit | 2324 | 0.109 | 0.4278 | Yes |
| 16 | ATP5O | ATP5O Entrez, Source | ATP synthase, H+ transporting, mitochondrial F1 complex, O subunit (oligomycin sensitivity conferring protein) | 2450 | 0.105 | 0.4379 | Yes |
| 17 | TIMM8B | TIMM8B Entrez, Source | translocase of inner mitochondrial membrane 8 homolog B (yeast) | 2592 | 0.100 | 0.4459 | Yes |
| 18 | NDUFS7 | NDUFS7 Entrez, Source | NADH dehydrogenase (ubiquinone) Fe-S protein 7, 20kDa (NADH-coenzyme Q reductase) | 2674 | 0.096 | 0.4578 | Yes |
| 19 | SDHA | SDHA Entrez, Source | succinate dehydrogenase complex, subunit A, flavoprotein (Fp) | 2886 | 0.088 | 0.4584 | Yes |
| 20 | NDUFS2 | NDUFS2 Entrez, Source | NADH dehydrogenase (ubiquinone) Fe-S protein 2, 49kDa (NADH-coenzyme Q reductase) | 2926 | 0.087 | 0.4718 | Yes |
| 21 | ATP5G3 | ATP5G3 Entrez, Source | ATP synthase, H+ transporting, mitochondrial F0 complex, subunit C3 (subunit 9) | 3038 | 0.084 | 0.4791 | Yes |
| 22 | SURF1 | SURF1 Entrez, Source | surfeit 1 | 3098 | 0.082 | 0.4899 | Yes |
| 23 | ATP5J | ATP5J Entrez, Source | ATP synthase, H+ transporting, mitochondrial F0 complex, subunit F6 | 3709 | 0.066 | 0.4563 | No |
| 24 | ATP5G2 | ATP5G2 Entrez, Source | ATP synthase, H+ transporting, mitochondrial F0 complex, subunit C2 (subunit 9) | 3731 | 0.066 | 0.4670 | No |
| 25 | ATP5A1 | ATP5A1 Entrez, Source | ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1, cardiac muscle | 3895 | 0.062 | 0.4664 | No |
| 26 | NDUFV1 | NDUFV1 Entrez, Source | NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa | 3926 | 0.061 | 0.4756 | No |
| 27 | PHB | PHB Entrez, Source | prohibitin | 3983 | 0.060 | 0.4825 | No |
| 28 | ATP5C1 | ATP5C1 Entrez, Source | ATP synthase, H+ transporting, mitochondrial F1 complex, gamma polypeptide 1 | 4283 | 0.053 | 0.4700 | No |
| 29 | UQCRC1 | UQCRC1 Entrez, Source | ubiquinol-cytochrome c reductase core protein I | 4861 | 0.041 | 0.4341 | No |
| 30 | UQCRH | UQCRH Entrez, Source | ubiquinol-cytochrome c reductase hinge protein | 4966 | 0.039 | 0.4335 | No |
| 31 | LBR | LBR Entrez, Source | lamin B receptor | 4976 | 0.038 | 0.4400 | No |
| 32 | OPA1 | OPA1 Entrez, Source | optic atrophy 1 (autosomal dominant) | 5005 | 0.038 | 0.4449 | No |
| 33 | ATP5D | ATP5D Entrez, Source | ATP synthase, H+ transporting, mitochondrial F1 complex, delta subunit | 5013 | 0.038 | 0.4515 | No |
| 34 | NDUFS1 | NDUFS1 Entrez, Source | NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase) | 5395 | 0.030 | 0.4284 | No |
| 35 | PSEN2 | PSEN2 Entrez, Source | presenilin 2 (Alzheimer disease 4) | 5670 | 0.024 | 0.4123 | No |
| 36 | ATP5B | ATP5B Entrez, Source | ATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide | 5777 | 0.022 | 0.4085 | No |
| 37 | PHB2 | PHB2 Entrez, Source | prohibitin 2 | 6088 | 0.016 | 0.3883 | No |
| 38 | NDUFS4 | NDUFS4 Entrez, Source | NADH dehydrogenase (ubiquinone) Fe-S protein 4, 18kDa (NADH-coenzyme Q reductase) | 6477 | 0.008 | 0.3606 | No |
| 39 | NDUFA9 | NDUFA9 Entrez, Source | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 9, 39kDa | 6665 | 0.005 | 0.3475 | No |
| 40 | IMMT | IMMT Entrez, Source | inner membrane protein, mitochondrial (mitofilin) | 6876 | 0.001 | 0.3318 | No |
| 41 | PSEN1 | PSEN1 Entrez, Source | presenilin 1 (Alzheimer disease 3) | 6918 | -0.000 | 0.3288 | No |
| 42 | TIMM13 | TIMM13 Entrez, Source | translocase of inner mitochondrial membrane 13 homolog (yeast) | 8076 | -0.025 | 0.2464 | No |
| 43 | TIMM17A | TIMM17A Entrez, Source | translocase of inner mitochondrial membrane 17 homolog A (yeast) | 8212 | -0.028 | 0.2414 | No |
| 44 | SLC25A11 | SLC25A11 Entrez, Source | solute carrier family 25 (mitochondrial carrier; oxoglutarate carrier), member 11 | 8929 | -0.044 | 0.1958 | No |
| 45 | UCP3 | UCP3 Entrez, Source | uncoupling protein 3 (mitochondrial, proton carrier) | 9230 | -0.052 | 0.1830 | No |
| 46 | PMPCA | PMPCA Entrez, Source | peptidase (mitochondrial processing) alpha | 9532 | -0.061 | 0.1717 | No |
| 47 | SLC25A3 | SLC25A3 Entrez, Source | solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3 | 10075 | -0.077 | 0.1453 | No |
| 48 | LMNB1 | LMNB1 Entrez, Source | lamin B1 | 11329 | -0.128 | 0.0748 | No |
| 49 | MATR3 | MATR3 Entrez, Source | matrin 3 | 11605 | -0.144 | 0.0810 | No |
| 50 | COX15 | COX15 Entrez, Source | COX15 homolog, cytochrome c oxidase assembly protein (yeast) | 12707 | -0.266 | 0.0478 | No |
