Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_single_gel_8d.class.cls #double_gel_8d_versus_single_gel_8d_repos |
| Phenotype | class.cls#double_gel_8d_versus_single_gel_8d_repos |
| Upregulated in class | double_gel_8d |
| GeneSet | OXIDOREDUCTASE_ACTIVITY__ACTING_ON_CH_OH_GROUP_OF_DONORS |
| Enrichment Score (ES) | 0.6549685 |
| Normalized Enrichment Score (NES) | 2.0708694 |
| Nominal p-value | 0.0 |
| FDR q-value | 6.3356914E-4 |
| FWER p-Value | 0.042 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | EHHADH | EHHADH Entrez, Source | enoyl-Coenzyme A, hydratase/3-hydroxyacyl Coenzyme A dehydrogenase | 24 | 0.864 | 0.1176 | Yes |
| 2 | ADH7 | ADH7 Entrez, Source | alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide | 50 | 0.751 | 0.2195 | Yes |
| 3 | HSD17B7 | HSD17B7 Entrez, Source | hydroxysteroid (17-beta) dehydrogenase 7 | 74 | 0.685 | 0.3124 | Yes |
| 4 | MIOX | MIOX Entrez, Source | myo-inositol oxygenase | 103 | 0.612 | 0.3948 | Yes |
| 5 | GPD1 | GPD1 Entrez, Source | glycerol-3-phosphate dehydrogenase 1 (soluble) | 189 | 0.483 | 0.4552 | Yes |
| 6 | HSD3B1 | HSD3B1 Entrez, Source | hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 | 293 | 0.402 | 0.5030 | Yes |
| 7 | NSDHL | NSDHL Entrez, Source | NAD(P) dependent steroid dehydrogenase-like | 829 | 0.216 | 0.4926 | Yes |
| 8 | HSD17B4 | HSD17B4 Entrez, Source | hydroxysteroid (17-beta) dehydrogenase 4 | 1074 | 0.185 | 0.4998 | Yes |
| 9 | HAO2 | HAO2 Entrez, Source | hydroxyacid oxidase 2 (long chain) | 1180 | 0.172 | 0.5157 | Yes |
| 10 | IDH1 | IDH1 Entrez, Source | isocitrate dehydrogenase 1 (NADP+), soluble | 1183 | 0.172 | 0.5394 | Yes |
| 11 | HADHA | HADHA Entrez, Source | hydroxyacyl-Coenzyme A dehydrogenase/3-ketoacyl-Coenzyme A thiolase/enoyl-Coenzyme A hydratase (trifunctional protein), alpha subunit | 1399 | 0.157 | 0.5449 | Yes |
| 12 | PHGDH | PHGDH Entrez, Source | phosphoglycerate dehydrogenase | 1496 | 0.150 | 0.5584 | Yes |
| 13 | ME1 | ME1 Entrez, Source | malic enzyme 1, NADP(+)-dependent, cytosolic | 1535 | 0.147 | 0.5759 | Yes |
| 14 | HADH | HADH Entrez, Source | hydroxyacyl-Coenzyme A dehydrogenase | 1615 | 0.142 | 0.5896 | Yes |
| 15 | BDH1 | BDH1 Entrez, Source | 3-hydroxybutyrate dehydrogenase, type 1 | 1686 | 0.138 | 0.6033 | Yes |
| 16 | HADHB | HADHB Entrez, Source | hydroxyacyl-Coenzyme A dehydrogenase/3-ketoacyl-Coenzyme A thiolase/enoyl-Coenzyme A hydratase (trifunctional protein), beta subunit | 1747 | 0.134 | 0.6174 | Yes |
| 17 | DHRS9 | DHRS9 Entrez, Source | dehydrogenase/reductase (SDR family) member 9 | 1998 | 0.122 | 0.6154 | Yes |
| 18 | RDH11 | RDH11 Entrez, Source | retinol dehydrogenase 11 (all-trans/9-cis/11-cis) | 2018 | 0.121 | 0.6306 | Yes |
| 19 | LDHA | LDHA Entrez, Source | lactate dehydrogenase A | 2134 | 0.117 | 0.6381 | Yes |
| 20 | MDH1 | MDH1 Entrez, Source | malate dehydrogenase 1, NAD (soluble) | 2361 | 0.108 | 0.6361 | Yes |
| 21 | ADH6 | ADH6 Entrez, Source | alcohol dehydrogenase 6 (class V) | 2402 | 0.107 | 0.6478 | Yes |
| 22 | SPR | SPR Entrez, Source | sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase) | 2551 | 0.101 | 0.6506 | Yes |
| 23 | GPD2 | GPD2 Entrez, Source | glycerol-3-phosphate dehydrogenase 2 (mitochondrial) | 2771 | 0.093 | 0.6470 | Yes |
| 24 | HPGD | HPGD Entrez, Source | hydroxyprostaglandin dehydrogenase 15-(NAD) | 2832 | 0.090 | 0.6550 | Yes |
| 25 | RDH10 | RDH10 Entrez, Source | retinol dehydrogenase 10 (all-trans) | 3161 | 0.080 | 0.6413 | No |
| 26 | AKR7A2 | AKR7A2 Entrez, Source | aldo-keto reductase family 7, member A2 (aflatoxin aldehyde reductase) | 3278 | 0.077 | 0.6432 | No |
| 27 | IDH3B | IDH3B Entrez, Source | isocitrate dehydrogenase 3 (NAD+) beta | 3545 | 0.070 | 0.6329 | No |
| 28 | LDHC | LDHC Entrez, Source | lactate dehydrogenase C | 3707 | 0.066 | 0.6299 | No |
| 29 | AKR1B10 | AKR1B10 Entrez, Source | aldo-keto reductase family 1, member B10 (aldose reductase) | 4097 | 0.057 | 0.6086 | No |
| 30 | ALDH3A1 | ALDH3A1 Entrez, Source | aldehyde dehydrogenase 3 family, memberA1 | 4305 | 0.053 | 0.6003 | No |
| 31 | ADH4 | ADH4 Entrez, Source | alcohol dehydrogenase 4 (class II), pi polypeptide | 5822 | 0.022 | 0.4894 | No |
| 32 | AKR7A3 | AKR7A3 Entrez, Source | aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase) | 5906 | 0.020 | 0.4859 | No |
| 33 | IMPDH2 | IMPDH2 Entrez, Source | IMP (inosine monophosphate) dehydrogenase 2 | 7268 | -0.008 | 0.3847 | No |
| 34 | IDH3G | IDH3G Entrez, Source | isocitrate dehydrogenase 3 (NAD+) gamma | 8587 | -0.037 | 0.2907 | No |
| 35 | LDHB | LDHB Entrez, Source | lactate dehydrogenase B | 10723 | -0.099 | 0.1439 | No |
| 36 | AKR1A1 | AKR1A1 Entrez, Source | aldo-keto reductase family 1, member A1 (aldehyde reductase) | 10743 | -0.100 | 0.1563 | No |
| 37 | UGDH | UGDH Entrez, Source | UDP-glucose dehydrogenase | 11033 | -0.113 | 0.1503 | No |
| 38 | CBR1 | CBR1 Entrez, Source | carbonyl reductase 1 | 11937 | -0.168 | 0.1056 | No |
