Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_single_gel_8d.class.cls #double_gel_8d_versus_single_gel_8d_repos |
| Phenotype | class.cls#double_gel_8d_versus_single_gel_8d_repos |
| Upregulated in class | single_gel_8d |
| GeneSet | OXSTRESS_RPETWO_DN |
| Enrichment Score (ES) | -0.5000378 |
| Normalized Enrichment Score (NES) | -1.7338446 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.067175746 |
| FWER p-Value | 0.998 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | RARB | RARB Entrez, Source | retinoic acid receptor, beta | 101 | 0.614 | 0.0374 | No |
| 2 | HGFAC | HGFAC Entrez, Source | HGF activator | 665 | 0.249 | 0.0132 | No |
| 3 | VCAM1 | VCAM1 Entrez, Source | vascular cell adhesion molecule 1 | 1016 | 0.190 | 0.0008 | No |
| 4 | CDH11 | CDH11 Entrez, Source | cadherin 11, type 2, OB-cadherin (osteoblast) | 1034 | 0.189 | 0.0133 | No |
| 5 | TNFRSF1A | TNFRSF1A Entrez, Source | tumor necrosis factor receptor superfamily, member 1A | 1920 | 0.125 | -0.0443 | No |
| 6 | CCR1 | CCR1 Entrez, Source | chemokine (C-C motif) receptor 1 | 2108 | 0.117 | -0.0498 | No |
| 7 | BMP4 | BMP4 Entrez, Source | bone morphogenetic protein 4 | 2116 | 0.117 | -0.0417 | No |
| 8 | FASTK | FASTK Entrez, Source | Fas-activated serine/threonine kinase | 2218 | 0.114 | -0.0410 | No |
| 9 | RB1 | RB1 Entrez, Source | retinoblastoma 1 (including osteosarcoma) | 2307 | 0.110 | -0.0396 | No |
| 10 | ERBB4 | ERBB4 Entrez, Source | v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian) | 2318 | 0.110 | -0.0323 | No |
| 11 | CDH2 | CDH2 Entrez, Source | cadherin 2, type 1, N-cadherin (neuronal) | 2409 | 0.106 | -0.0313 | No |
| 12 | HINT1 | HINT1 Entrez, Source | histidine triad nucleotide binding protein 1 | 2835 | 0.090 | -0.0567 | No |
| 13 | DDR2 | DDR2 Entrez, Source | discoidin domain receptor family, member 2 | 3366 | 0.074 | -0.0913 | No |
| 14 | MARK3 | MARK3 Entrez, Source | MAP/microtubule affinity-regulating kinase 3 | 3431 | 0.073 | -0.0907 | No |
| 15 | TERF1 | TERF1 Entrez, Source | telomeric repeat binding factor (NIMA-interacting) 1 | 3490 | 0.071 | -0.0899 | No |
| 16 | MYC | MYC Entrez, Source | v-myc myelocytomatosis viral oncogene homolog (avian) | 3805 | 0.064 | -0.1089 | No |
| 17 | ITGAL | ITGAL Entrez, Source | integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide) | 3846 | 0.063 | -0.1073 | No |
| 18 | CREB1 | CREB1 Entrez, Source | cAMP responsive element binding protein 1 | 3915 | 0.062 | -0.1079 | No |
| 19 | PHB | PHB Entrez, Source | prohibitin | 3983 | 0.060 | -0.1086 | No |
| 20 | ITGB5 | ITGB5 Entrez, Source | integrin, beta 5 | 3998 | 0.059 | -0.1053 | No |
| 21 | IGF1R | IGF1R Entrez, Source | insulin-like growth factor 1 receptor | 4105 | 0.057 | -0.1091 | No |
| 22 | ITGA7 | ITGA7 Entrez, Source | integrin, alpha 7 | 4309 | 0.053 | -0.1205 | No |
| 23 | CDC25A | CDC25A Entrez, Source | cell division cycle 25A | 4801 | 0.042 | -0.1545 | No |
| 24 | IL3 | IL3 Entrez, Source | interleukin 3 (colony-stimulating factor, multiple) | 5075 | 0.036 | -0.1724 | No |
| 25 | CSNK1G2 | CSNK1G2 Entrez, Source | casein kinase 1, gamma 2 | 5264 | 0.033 | -0.1842 | No |
| 26 | BRAF | BRAF Entrez, Source | v-raf murine sarcoma viral oncogene homolog B1 | 5502 | 0.028 | -0.2001 | No |
| 27 | LYN | LYN Entrez, Source | v-yes-1 Yamaguchi sarcoma viral related oncogene homolog | 5855 | 0.021 | -0.2251 | No |
| 28 | HGF | HGF Entrez, Source | hepatocyte growth factor (hepapoietin A; scatter factor) | 5893 | 0.020 | -0.2264 | No |
| 29 | FGFR1 | FGFR1 Entrez, Source | fibroblast growth factor receptor 1 (fms-related tyrosine kinase 2, Pfeiffer syndrome) | 6165 | 0.015 | -0.2457 | No |
| 30 | TCEA1 | TCEA1 Entrez, Source | transcription elongation factor A (SII), 1 | 6329 | 0.011 | -0.2572 | No |
| 31 | STCH | STCH Entrez, Source | stress 70 protein chaperone, microsome-associated, 60kDa | 6424 | 0.009 | -0.2636 | No |
| 32 | UBE2A | UBE2A Entrez, Source | ubiquitin-conjugating enzyme E2A (RAD6 homolog) | 6804 | 0.002 | -0.2920 | No |
| 33 | PPP3CA | PPP3CA Entrez, Source | protein phosphatase 3 (formerly 2B), catalytic subunit, alpha isoform (calcineurin A alpha) | 7108 | -0.004 | -0.3146 | No |
| 34 | CSDA | CSDA Entrez, Source | cold shock domain protein A | 7299 | -0.008 | -0.3283 | No |
| 35 | CDKN2B | CDKN2B Entrez, Source | cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4) | 7589 | -0.014 | -0.3490 | No |
| 36 | CDK9 | CDK9 Entrez, Source | cyclin-dependent kinase 9 (CDC2-related kinase) | 7754 | -0.018 | -0.3601 | No |
| 37 | FMO1 | FMO1 Entrez, Source | flavin containing monooxygenase 1 | 7782 | -0.018 | -0.3608 | No |
| 38 | TSG101 | TSG101 Entrez, Source | tumor susceptibility gene 101 | 8160 | -0.027 | -0.3873 | No |
| 39 | SLC7A5 | SLC7A5 Entrez, Source | solute carrier family 7 (cationic amino acid transporter, y+ system), member 5 | 8548 | -0.036 | -0.4138 | No |
| 40 | BCL2L1 | BCL2L1 Entrez, Source | BCL2-like 1 | 8585 | -0.037 | -0.4139 | No |
| 41 | GPX2 | GPX2 Entrez, Source | glutathione peroxidase 2 (gastrointestinal) | 8597 | -0.037 | -0.4120 | No |
| 42 | BMP1 | BMP1 Entrez, Source | bone morphogenetic protein 1 | 9411 | -0.057 | -0.4691 | No |
| 43 | ELK1 | ELK1 Entrez, Source | ELK1, member of ETS oncogene family | 9587 | -0.062 | -0.4778 | No |
| 44 | DFFB | DFFB Entrez, Source | DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase) | 9728 | -0.066 | -0.4835 | No |
| 45 | RXRB | RXRB Entrez, Source | retinoid X receptor, beta | 9739 | -0.066 | -0.4794 | No |
| 46 | GTF2B | GTF2B Entrez, Source | general transcription factor IIB | 9753 | -0.067 | -0.4755 | No |
| 47 | GAK | GAK Entrez, Source | cyclin G associated kinase | 9786 | -0.067 | -0.4730 | No |
| 48 | CDKN2D | CDKN2D Entrez, Source | cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4) | 9788 | -0.068 | -0.4681 | No |
| 49 | YWHAH | YWHAH Entrez, Source | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide | 9794 | -0.068 | -0.4635 | No |
| 50 | SPINT2 | SPINT2 Entrez, Source | serine peptidase inhibitor, Kunitz type, 2 | 9927 | -0.073 | -0.4681 | No |
| 51 | ARHGDIA | ARHGDIA Entrez, Source | Rho GDP dissociation inhibitor (GDI) alpha | 9931 | -0.073 | -0.4631 | No |
| 52 | GNB2 | GNB2 Entrez, Source | guanine nucleotide binding protein (G protein), beta polypeptide 2 | 10152 | -0.080 | -0.4738 | No |
| 53 | ITSN1 | ITSN1 Entrez, Source | intersectin 1 (SH3 domain protein) | 10184 | -0.081 | -0.4702 | No |
| 54 | CTNNB1 | CTNNB1 Entrez, Source | catenin (cadherin-associated protein), beta 1, 88kDa | 10376 | -0.087 | -0.4782 | No |
| 55 | QSCN6 | QSCN6 Entrez, Source | quiescin Q6 | 10576 | -0.094 | -0.4863 | No |
| 56 | ACTB | ACTB Entrez, Source | actin, beta | 10590 | -0.095 | -0.4804 | No |
| 57 | PPP1CA | PPP1CA Entrez, Source | protein phosphatase 1, catalytic subunit, alpha isoform | 10852 | -0.105 | -0.4924 | Yes |
| 58 | SMAD1 | SMAD1 Entrez, Source | SMAD, mothers against DPP homolog 1 (Drosophila) | 10869 | -0.105 | -0.4858 | Yes |
| 59 | RPL13A | RPL13A Entrez, Source | ribosomal protein L13a | 10925 | -0.108 | -0.4821 | Yes |
| 60 | CDC20 | CDC20 Entrez, Source | CDC20 cell division cycle 20 homolog (S. cerevisiae) | 11099 | -0.117 | -0.4866 | Yes |
| 61 | S100A1 | S100A1 Entrez, Source | S100 calcium binding protein A1 | 11272 | -0.125 | -0.4904 | Yes |
| 62 | RNH1 | RNH1 Entrez, Source | ribonuclease/angiogenin inhibitor 1 | 11349 | -0.129 | -0.4867 | Yes |
| 63 | TSC2 | TSC2 Entrez, Source | tuberous sclerosis 2 | 11382 | -0.130 | -0.4795 | Yes |
| 64 | CD47 | CD47 Entrez, Source | CD47 molecule | 11473 | -0.136 | -0.4764 | Yes |
| 65 | CAPN2 | CAPN2 Entrez, Source | calpain 2, (m/II) large subunit | 11562 | -0.141 | -0.4727 | Yes |
| 66 | TP53 | TP53 Entrez, Source | tumor protein p53 (Li-Fraumeni syndrome) | 11690 | -0.149 | -0.4714 | Yes |
| 67 | DYNLL1 | DYNLL1 Entrez, Source | dynein, light chain, LC8-type 1 | 11702 | -0.150 | -0.4612 | Yes |
| 68 | BAD | BAD Entrez, Source | BCL2-antagonist of cell death | 11752 | -0.152 | -0.4537 | Yes |
| 69 | CLU | CLU Entrez, Source | clusterin | 11779 | -0.155 | -0.4443 | Yes |
| 70 | ITGB4 | ITGB4 Entrez, Source | integrin, beta 4 | 11844 | -0.160 | -0.4375 | Yes |
| 71 | TPP1 | TPP1 Entrez, Source | tripeptidyl peptidase I | 11989 | -0.172 | -0.4357 | Yes |
| 72 | BAK1 | BAK1 Entrez, Source | BCL2-antagonist/killer 1 | 12372 | -0.212 | -0.4490 | Yes |
| 73 | IL18 | IL18 Entrez, Source | interleukin 18 (interferon-gamma-inducing factor) | 12497 | -0.228 | -0.4416 | Yes |
| 74 | HBEGF | HBEGF Entrez, Source | heparin-binding EGF-like growth factor | 12714 | -0.267 | -0.4383 | Yes |
| 75 | ITGA6 | ITGA6 Entrez, Source | integrin, alpha 6 | 12719 | -0.269 | -0.4189 | Yes |
| 76 | ZYX | ZYX Entrez, Source | zyxin | 12724 | -0.270 | -0.3994 | Yes |
| 77 | CDKN1C | CDKN1C Entrez, Source | cyclin-dependent kinase inhibitor 1C (p57, Kip2) | 12725 | -0.270 | -0.3796 | Yes |
| 78 | ETS1 | ETS1 Entrez, Source | v-ets erythroblastosis virus E26 oncogene homolog 1 (avian) | 12786 | -0.282 | -0.3635 | Yes |
| 79 | SPRY2 | SPRY2 Entrez, Source | sprouty homolog 2 (Drosophila) | 13095 | -0.423 | -0.3557 | Yes |
| 80 | F2R | F2R Entrez, Source | coagulation factor II (thrombin) receptor | 13270 | -0.762 | -0.3130 | Yes |
| 81 | VIL2 | VIL2 Entrez, Source | villin 2 (ezrin) | 13271 | -0.763 | -0.2571 | Yes |
| 82 | MMP11 | MMP11 Entrez, Source | matrix metallopeptidase 11 (stromelysin 3) | 13273 | -0.768 | -0.2009 | Yes |
| 83 | MARCKSL1 | MARCKSL1 Entrez, Source | MARCKS-like 1 | 13312 | -1.018 | -0.1291 | Yes |
| 84 | CPE | CPE Entrez, Source | carboxypeptidase E | 13342 | -1.792 | 0.0000 | Yes |
