Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_single_gel_8d.class.cls #double_gel_8d_versus_single_gel_8d_repos |
| Phenotype | class.cls#double_gel_8d_versus_single_gel_8d_repos |
| Upregulated in class | single_gel_8d |
| GeneSet | P38MAPKPATHWAY |
| Enrichment Score (ES) | -0.62032217 |
| Normalized Enrichment Score (NES) | -1.7567724 |
| Nominal p-value | 0.003875969 |
| FDR q-value | 0.060601223 |
| FWER p-Value | 0.988 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | MAX | MAX Entrez, Source | MYC associated factor X | 1464 | 0.152 | -0.0740 | No |
| 2 | HRAS | HRAS Entrez, Source | v-Ha-ras Harvey rat sarcoma viral oncogene homolog | 2898 | 0.088 | -0.1608 | No |
| 3 | MAPK14 | MAPK14 Entrez, Source | mitogen-activated protein kinase 14 | 2979 | 0.086 | -0.1466 | No |
| 4 | SHC1 | SHC1 Entrez, Source | SHC (Src homology 2 domain containing) transforming protein 1 | 3311 | 0.076 | -0.1535 | No |
| 5 | MYC | MYC Entrez, Source | v-myc myelocytomatosis viral oncogene homolog (avian) | 3805 | 0.064 | -0.1754 | No |
| 6 | CREB1 | CREB1 Entrez, Source | cAMP responsive element binding protein 1 | 3915 | 0.062 | -0.1690 | No |
| 7 | HSPB2 | HSPB2 Entrez, Source | heat shock 27kDa protein 2 | 3966 | 0.060 | -0.1584 | No |
| 8 | MEF2D | MEF2D Entrez, Source | MADS box transcription enhancer factor 2, polypeptide D (myocyte enhancer factor 2D) | 4769 | 0.042 | -0.2086 | No |
| 9 | STAT1 | STAT1 Entrez, Source | signal transducer and activator of transcription 1, 91kDa | 4819 | 0.041 | -0.2025 | No |
| 10 | DAXX | DAXX Entrez, Source | death-associated protein 6 | 6115 | 0.016 | -0.2960 | No |
| 11 | CDC42 | CDC42 Entrez, Source | cell division cycle 42 (GTP binding protein, 25kDa) | 7461 | -0.012 | -0.3943 | No |
| 12 | MAP2K6 | MAP2K6 Entrez, Source | mitogen-activated protein kinase kinase 6 | 7666 | -0.016 | -0.4059 | No |
| 13 | TRADD | TRADD Entrez, Source | TNFRSF1A-associated via death domain | 8465 | -0.033 | -0.4579 | No |
| 14 | MAPKAPK2 | MAPKAPK2 Entrez, Source | mitogen-activated protein kinase-activated protein kinase 2 | 8907 | -0.044 | -0.4807 | No |
| 15 | ELK1 | ELK1 Entrez, Source | ELK1, member of ETS oncogene family | 9587 | -0.062 | -0.5169 | No |
| 16 | GRB2 | GRB2 Entrez, Source | growth factor receptor-bound protein 2 | 9756 | -0.067 | -0.5138 | No |
| 17 | HMGN1 | HMGN1 Entrez, Source | high-mobility group nucleosome binding domain 1 | 9807 | -0.069 | -0.5013 | No |
| 18 | RAC1 | RAC1 Entrez, Source | ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) | 9885 | -0.071 | -0.4903 | No |
| 19 | MAP2K4 | MAP2K4 Entrez, Source | mitogen-activated protein kinase kinase 4 | 10267 | -0.084 | -0.4991 | No |
| 20 | ATF2 | ATF2 Entrez, Source | activating transcription factor 2 | 11597 | -0.143 | -0.5650 | No |
| 21 | DDIT3 | DDIT3 Entrez, Source | DNA-damage-inducible transcript 3 | 12335 | -0.209 | -0.5709 | Yes |
| 22 | TGFBR1 | TGFBR1 Entrez, Source | transforming growth factor, beta receptor I (activin A receptor type II-like kinase, 53kDa) | 12538 | -0.234 | -0.5308 | Yes |
| 23 | TGFB2 | TGFB2 Entrez, Source | transforming growth factor, beta 2 | 12832 | -0.296 | -0.4828 | Yes |
| 24 | HSPB1 | HSPB1 Entrez, Source | heat shock 27kDa protein 1 | 12892 | -0.318 | -0.4120 | Yes |
| 25 | PLA2G4A | PLA2G4A Entrez, Source | phospholipase A2, group IVA (cytosolic, calcium-dependent) | 12946 | -0.338 | -0.3361 | Yes |
| 26 | MAP3K1 | MAP3K1 Entrez, Source | mitogen-activated protein kinase kinase kinase 1 | 13003 | -0.366 | -0.2536 | Yes |
| 27 | TGFB1 | TGFB1 Entrez, Source | transforming growth factor, beta 1 (Camurati-Engelmann disease) | 13047 | -0.395 | -0.1633 | Yes |
| 28 | TGFB3 | TGFB3 Entrez, Source | transforming growth factor, beta 3 | 13277 | -0.783 | 0.0049 | Yes |
