Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_single_gel_8d.class.cls #double_gel_8d_versus_single_gel_8d_repos |
| Phenotype | class.cls#double_gel_8d_versus_single_gel_8d_repos |
| Upregulated in class | double_gel_8d |
| GeneSet | PPARAPATHWAY |
| Enrichment Score (ES) | 0.6096904 |
| Normalized Enrichment Score (NES) | 1.94204 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.0033871452 |
| FWER p-Value | 0.279 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | APOA2 | APOA2 Entrez, Source | apolipoprotein A-II | 7 | 1.206 | 0.1317 | Yes |
| 2 | FABP1 | FABP1 Entrez, Source | fatty acid binding protein 1, liver | 8 | 1.205 | 0.2639 | Yes |
| 3 | EHHADH | EHHADH Entrez, Source | enoyl-Coenzyme A, hydratase/3-hydroxyacyl Coenzyme A dehydrogenase | 24 | 0.864 | 0.3575 | Yes |
| 4 | NR0B2 | NR0B2 Entrez, Source | nuclear receptor subfamily 0, group B, member 2 | 187 | 0.486 | 0.3986 | Yes |
| 5 | LPL | LPL Entrez, Source | lipoprotein lipase | 230 | 0.451 | 0.4450 | Yes |
| 6 | RXRA | RXRA Entrez, Source | retinoid X receptor, alpha | 375 | 0.353 | 0.4728 | Yes |
| 7 | ACOX1 | ACOX1 Entrez, Source | acyl-Coenzyme A oxidase 1, palmitoyl | 429 | 0.329 | 0.5050 | Yes |
| 8 | NR1H3 | NR1H3 Entrez, Source | nuclear receptor subfamily 1, group H, member 3 | 540 | 0.287 | 0.5282 | Yes |
| 9 | NFKBIA | NFKBIA Entrez, Source | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 670 | 0.247 | 0.5456 | Yes |
| 10 | PPARA | PPARA Entrez, Source | peroxisome proliferative activated receptor, alpha | 732 | 0.231 | 0.5663 | Yes |
| 11 | PRKCA | PRKCA Entrez, Source | protein kinase C, alpha | 736 | 0.230 | 0.5913 | Yes |
| 12 | APOA1 | APOA1 Entrez, Source | apolipoprotein A-I | 1052 | 0.187 | 0.5882 | Yes |
| 13 | HSD17B4 | HSD17B4 Entrez, Source | hydroxysteroid (17-beta) dehydrogenase 4 | 1074 | 0.185 | 0.6068 | Yes |
| 14 | CPT1B | CPT1B Entrez, Source | carnitine palmitoyltransferase 1B (muscle) | 1278 | 0.165 | 0.6097 | Yes |
| 15 | ME1 | ME1 Entrez, Source | malic enzyme 1, NADP(+)-dependent, cytosolic | 1535 | 0.147 | 0.6066 | No |
| 16 | CREBBP | CREBBP Entrez, Source | CREB binding protein (Rubinstein-Taybi syndrome) | 2102 | 0.118 | 0.5769 | No |
| 17 | RB1 | RB1 Entrez, Source | retinoblastoma 1 (including osteosarcoma) | 2307 | 0.110 | 0.5736 | No |
| 18 | SRA1 | SRA1 Entrez, Source | steroid receptor RNA activator 1 | 2775 | 0.093 | 0.5487 | No |
| 19 | DUSP1 | DUSP1 Entrez, Source | dual specificity phosphatase 1 | 3275 | 0.077 | 0.5195 | No |
| 20 | TNF | TNF Entrez, Source | tumor necrosis factor (TNF superfamily, member 2) | 3489 | 0.071 | 0.5114 | No |
| 21 | MYC | MYC Entrez, Source | v-myc myelocytomatosis viral oncogene homolog (avian) | 3805 | 0.064 | 0.4947 | No |
| 22 | PIK3R1 | PIK3R1 Entrez, Source | phosphoinositide-3-kinase, regulatory subunit 1 (p85 alpha) | 3876 | 0.062 | 0.4963 | No |
| 23 | PRKCB1 | PRKCB1 Entrez, Source | protein kinase C, beta 1 | 4062 | 0.058 | 0.4887 | No |
| 24 | MRPL11 | MRPL11 Entrez, Source | mitochondrial ribosomal protein L11 | 4485 | 0.049 | 0.4624 | No |
| 25 | PRKAR2A | PRKAR2A Entrez, Source | protein kinase, cAMP-dependent, regulatory, type II, alpha | 5253 | 0.033 | 0.4083 | No |
| 26 | NR2F1 | NR2F1 Entrez, Source | nuclear receptor subfamily 2, group F, member 1 | 7183 | -0.006 | 0.2639 | No |
| 27 | RELA | RELA Entrez, Source | v-rel reticuloendotheliosis viral oncogene homolog A, nuclear factor of kappa light polypeptide gene enhancer in B-cells 3, p65 (avian) | 7310 | -0.008 | 0.2553 | No |
| 28 | MAPK1 | MAPK1 Entrez, Source | mitogen-activated protein kinase 1 | 7490 | -0.012 | 0.2432 | No |
| 29 | PRKAR1B | PRKAR1B Entrez, Source | protein kinase, cAMP-dependent, regulatory, type I, beta | 7501 | -0.012 | 0.2438 | No |
| 30 | STAT5A | STAT5A Entrez, Source | signal transducer and activator of transcription 5A | 8184 | -0.027 | 0.1955 | No |
| 31 | STAT5B | STAT5B Entrez, Source | signal transducer and activator of transcription 5B | 8858 | -0.043 | 0.1496 | No |
| 32 | SP1 | SP1 Entrez, Source | Sp1 transcription factor | 9134 | -0.050 | 0.1344 | No |
| 33 | JUN | JUN Entrez, Source | jun oncogene | 9748 | -0.066 | 0.0956 | No |
| 34 | PRKAR1A | PRKAR1A Entrez, Source | protein kinase, cAMP-dependent, regulatory, type I, alpha (tissue specific extinguisher 1) | 9898 | -0.071 | 0.0922 | No |
| 35 | MAPK3 | MAPK3 Entrez, Source | mitogen-activated protein kinase 3 | 10053 | -0.076 | 0.0890 | No |
| 36 | PTGS2 | PTGS2 Entrez, Source | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | 10604 | -0.095 | 0.0581 | No |
| 37 | NCOR1 | NCOR1 Entrez, Source | nuclear receptor co-repressor 1 | 10853 | -0.105 | 0.0509 | No |
| 38 | CITED2 | CITED2 Entrez, Source | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | 11087 | -0.116 | 0.0461 | No |
| 39 | DUT | DUT Entrez, Source | dUTP pyrophosphatase | 11400 | -0.131 | 0.0370 | No |
| 40 | PIK3CA | PIK3CA Entrez, Source | phosphoinositide-3-kinase, catalytic, alpha polypeptide | 11438 | -0.133 | 0.0489 | No |
| 41 | EP300 | EP300 Entrez, Source | E1A binding protein p300 | 12496 | -0.228 | -0.0056 | No |
| 42 | PDGFA | PDGFA Entrez, Source | platelet-derived growth factor alpha polypeptide | 12698 | -0.263 | 0.0082 | No |
| 43 | PRKAR2B | PRKAR2B Entrez, Source | protein kinase, cAMP-dependent, regulatory, type II, beta | 13002 | -0.366 | 0.0256 | No |
