Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_single_gel_8d.class.cls #double_gel_8d_versus_single_gel_8d_repos |
| Phenotype | class.cls#double_gel_8d_versus_single_gel_8d_repos |
| Upregulated in class | single_gel_8d |
| GeneSet | PROTEIN_IMPORT_INTO_NUCLEUS |
| Enrichment Score (ES) | -0.59487945 |
| Normalized Enrichment Score (NES) | -1.6293305 |
| Nominal p-value | 0.011173184 |
| FDR q-value | 0.10488983 |
| FWER p-Value | 1.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | F2 | F2 Entrez, Source | coagulation factor II (thrombin) | 413 | 0.335 | 0.0529 | No |
| 2 | PTTG1IP | PTTG1IP Entrez, Source | pituitary tumor-transforming 1 interacting protein | 3230 | 0.078 | -0.1391 | No |
| 3 | TNF | TNF Entrez, Source | tumor necrosis factor (TNF superfamily, member 2) | 3489 | 0.071 | -0.1405 | No |
| 4 | KPNA2 | KPNA2 Entrez, Source | karyopherin alpha 2 (RAG cohort 1, importin alpha 1) | 3717 | 0.066 | -0.1410 | No |
| 5 | KPNA1 | KPNA1 Entrez, Source | karyopherin alpha 1 (importin alpha 5) | 4415 | 0.050 | -0.1808 | No |
| 6 | FAF1 | FAF1 Entrez, Source | Fas (TNFRSF6) associated factor 1 | 4712 | 0.044 | -0.1920 | No |
| 7 | CDH1 | CDH1 Entrez, Source | cadherin 1, type 1, E-cadherin (epithelial) | 5558 | 0.026 | -0.2489 | No |
| 8 | NFKBIL1 | NFKBIL1 Entrez, Source | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1 | 5719 | 0.023 | -0.2551 | No |
| 9 | GLI3 | GLI3 Entrez, Source | GLI-Kruppel family member GLI3 (Greig cephalopolysyndactyly syndrome) | 6095 | 0.016 | -0.2791 | No |
| 10 | KPNB1 | KPNB1 Entrez, Source | karyopherin (importin) beta 1 | 9435 | -0.058 | -0.5153 | No |
| 11 | TPR | TPR Entrez, Source | translocated promoter region (to activated MET oncogene) | 10496 | -0.091 | -0.5720 | Yes |
| 12 | KPNA3 | KPNA3 Entrez, Source | karyopherin alpha 3 (importin alpha 4) | 10575 | -0.094 | -0.5543 | Yes |
| 13 | MXI1 | MXI1 Entrez, Source | MAX interactor 1 | 10722 | -0.099 | -0.5403 | Yes |
| 14 | CBLB | CBLB Entrez, Source | Cas-Br-M (murine) ecotropic retroviral transforming sequence b | 10938 | -0.109 | -0.5292 | Yes |
| 15 | PDIA3 | PDIA3 Entrez, Source | protein disulfide isomerase family A, member 3 | 11217 | -0.122 | -0.5195 | Yes |
| 16 | NF1 | NF1 Entrez, Source | neurofibromin 1 (neurofibromatosis, von Recklinghausen disease, Watson disease) | 11321 | -0.127 | -0.4953 | Yes |
| 17 | KPNA4 | KPNA4 Entrez, Source | karyopherin alpha 4 (importin alpha 3) | 11522 | -0.139 | -0.4756 | Yes |
| 18 | SMAD3 | SMAD3 Entrez, Source | SMAD, mothers against DPP homolog 3 (Drosophila) | 11527 | -0.139 | -0.4410 | Yes |
| 19 | PPP1R10 | PPP1R10 Entrez, Source | protein phosphatase 1, regulatory subunit 10 | 11590 | -0.143 | -0.4099 | Yes |
| 20 | AKT1 | AKT1 Entrez, Source | v-akt murine thymoma viral oncogene homolog 1 | 11801 | -0.156 | -0.3865 | Yes |
| 21 | TNPO1 | TNPO1 Entrez, Source | transportin 1 | 12075 | -0.179 | -0.3620 | Yes |
| 22 | RERE | RERE Entrez, Source | arginine-glutamic acid dipeptide (RE) repeats | 12466 | -0.223 | -0.3354 | Yes |
| 23 | TGFB1 | TGFB1 Entrez, Source | transforming growth factor, beta 1 (Camurati-Engelmann disease) | 13047 | -0.395 | -0.2799 | Yes |
| 24 | CEP57 | CEP57 Entrez, Source | centrosomal protein 57kDa | 13119 | -0.442 | -0.1744 | Yes |
| 25 | F2R | F2R Entrez, Source | coagulation factor II (thrombin) receptor | 13270 | -0.762 | 0.0054 | Yes |
