Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_single_gel_8d.class.cls #double_gel_8d_versus_single_gel_8d_repos |
| Phenotype | class.cls#double_gel_8d_versus_single_gel_8d_repos |
| Upregulated in class | single_gel_8d |
| GeneSet | REN_E2F1_TARGETS |
| Enrichment Score (ES) | -0.6139747 |
| Normalized Enrichment Score (NES) | -1.6337715 |
| Nominal p-value | 0.02131783 |
| FDR q-value | 0.102324486 |
| FWER p-Value | 1.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | MTHFD1 | MTHFD1 Entrez, Source | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase | 1050 | 0.187 | -0.0211 | No |
| 2 | RB1 | RB1 Entrez, Source | retinoblastoma 1 (including osteosarcoma) | 2307 | 0.110 | -0.0815 | No |
| 3 | UNG | UNG Entrez, Source | uracil-DNA glycosylase | 3194 | 0.079 | -0.1236 | No |
| 4 | MYC | MYC Entrez, Source | v-myc myelocytomatosis viral oncogene homolog (avian) | 3805 | 0.064 | -0.1497 | No |
| 5 | CDC25A | CDC25A Entrez, Source | cell division cycle 25A | 4801 | 0.042 | -0.2115 | No |
| 6 | SFRS2 | SFRS2 Entrez, Source | splicing factor, arginine/serine-rich 2 | 5597 | 0.026 | -0.2632 | No |
| 7 | CALR | CALR Entrez, Source | calreticulin | 6558 | 0.007 | -0.3332 | No |
| 8 | TOP2A | TOP2A Entrez, Source | topoisomerase (DNA) II alpha 170kDa | 6709 | 0.004 | -0.3433 | No |
| 9 | UMPS | UMPS Entrez, Source | uridine monophosphate synthetase (orotate phosphoribosyl transferase and orotidine-5'-decarboxylase) | 7149 | -0.005 | -0.3747 | No |
| 10 | NCL | NCL Entrez, Source | nucleolin | 9096 | -0.049 | -0.5058 | No |
| 11 | POLA2 | POLA2 Entrez, Source | polymerase (DNA directed), alpha 2 (70kD subunit) | 9233 | -0.052 | -0.4999 | No |
| 12 | PRPSAP1 | PRPSAP1 Entrez, Source | phosphoribosyl pyrophosphate synthetase-associated protein 1 | 9492 | -0.060 | -0.5008 | No |
| 13 | PCNA | PCNA Entrez, Source | proliferating cell nuclear antigen | 10651 | -0.097 | -0.5578 | No |
| 14 | DUT | DUT Entrez, Source | dUTP pyrophosphatase | 11400 | -0.131 | -0.5736 | Yes |
| 15 | CALM2 | CALM2 Entrez, Source | calmodulin 2 (phosphorylase kinase, delta) | 11648 | -0.147 | -0.5468 | Yes |
| 16 | RFC2 | RFC2 Entrez, Source | replication factor C (activator 1) 2, 40kDa | 11987 | -0.172 | -0.5192 | Yes |
| 17 | SLC3A2 | SLC3A2 Entrez, Source | solute carrier family 3 (activators of dibasic and neutral amino acid transport), member 2 | 12198 | -0.191 | -0.4758 | Yes |
| 18 | MSH2 | MSH2 Entrez, Source | mutS homolog 2, colon cancer, nonpolyposis type 1 (E. coli) | 12401 | -0.215 | -0.4247 | Yes |
| 19 | PRIM2A | PRIM2A Entrez, Source | primase, polypeptide 2A, 58kDa | 12498 | -0.229 | -0.3613 | Yes |
| 20 | RFC3 | RFC3 Entrez, Source | replication factor C (activator 1) 3, 38kDa | 12611 | -0.247 | -0.2935 | Yes |
| 21 | FEN1 | FEN1 Entrez, Source | flap structure-specific endonuclease 1 | 12720 | -0.269 | -0.2185 | Yes |
| 22 | ID3 | ID3 Entrez, Source | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein | 13077 | -0.411 | -0.1184 | Yes |
| 23 | KIAA0101 | KIAA0101 Entrez, Source | KIAA0101 | 13128 | -0.448 | 0.0161 | Yes |
