Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_single_gel_8d.class.cls #double_gel_8d_versus_single_gel_8d_repos |
| Phenotype | class.cls#double_gel_8d_versus_single_gel_8d_repos |
| Upregulated in class | double_gel_8d |
| GeneSet | RESPONSE_TO_WOUNDING |
| Enrichment Score (ES) | 0.42690542 |
| Normalized Enrichment Score (NES) | 1.6504427 |
| Nominal p-value | 0.0022779044 |
| FDR q-value | 0.048918787 |
| FWER p-Value | 1.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | PLG | PLG Entrez, Source | plasminogen | 44 | 0.773 | 0.0350 | Yes |
| 2 | TNFAIP6 | TNFAIP6 Entrez, Source | tumor necrosis factor, alpha-induced protein 6 | 64 | 0.710 | 0.0687 | Yes |
| 3 | CDO1 | CDO1 Entrez, Source | cysteine dioxygenase, type I | 104 | 0.612 | 0.0961 | Yes |
| 4 | F10 | F10 Entrez, Source | coagulation factor X | 141 | 0.550 | 0.1206 | Yes |
| 5 | CCL20 | CCL20 Entrez, Source | chemokine (C-C motif) ligand 20 | 166 | 0.509 | 0.1440 | Yes |
| 6 | F9 | F9 Entrez, Source | coagulation factor IX (plasma thromboplastic component, Christmas disease, hemophilia B) | 203 | 0.468 | 0.1645 | Yes |
| 7 | MGLL | MGLL Entrez, Source | monoglyceride lipase | 241 | 0.443 | 0.1836 | Yes |
| 8 | MBL2 | MBL2 Entrez, Source | mannose-binding lectin (protein C) 2, soluble (opsonic defect) | 263 | 0.424 | 0.2031 | Yes |
| 9 | CXCL2 | CXCL2 Entrez, Source | chemokine (C-X-C motif) ligand 2 | 267 | 0.421 | 0.2237 | Yes |
| 10 | FOS | FOS Entrez, Source | v-fos FBJ murine osteosarcoma viral oncogene homolog | 299 | 0.398 | 0.2411 | Yes |
| 11 | CXCL1 | CXCL1 Entrez, Source | chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) | 309 | 0.392 | 0.2598 | Yes |
| 12 | CFHR1 | CFHR1 Entrez, Source | complement factor H-related 1 | 350 | 0.362 | 0.2747 | Yes |
| 13 | F2 | F2 Entrez, Source | coagulation factor II (thrombin) | 413 | 0.335 | 0.2866 | Yes |
| 14 | CCL3 | CCL3 Entrez, Source | chemokine (C-C motif) ligand 3 | 447 | 0.321 | 0.3000 | Yes |
| 15 | TPST1 | TPST1 Entrez, Source | tyrosylprotein sulfotransferase 1 | 453 | 0.319 | 0.3155 | Yes |
| 16 | PROC | PROC Entrez, Source | protein C (inactivator of coagulation factors Va and VIIIa) | 476 | 0.310 | 0.3292 | Yes |
| 17 | CRP | CRP Entrez, Source | C-reactive protein, pentraxin-related | 534 | 0.289 | 0.3392 | Yes |
| 18 | CD40 | CD40 Entrez, Source | CD40 molecule, TNF receptor superfamily member 5 | 586 | 0.271 | 0.3488 | Yes |
| 19 | LBP | LBP Entrez, Source | lipopolysaccharide binding protein | 701 | 0.238 | 0.3519 | Yes |
| 20 | KLRG1 | KLRG1 Entrez, Source | killer cell lectin-like receptor subfamily G, member 1 | 729 | 0.233 | 0.3614 | Yes |
| 21 | C4BPB | C4BPB Entrez, Source | complement component 4 binding protein, beta | 763 | 0.225 | 0.3701 | Yes |
| 22 | ALOX5AP | ALOX5AP Entrez, Source | arachidonate 5-lipoxygenase-activating protein | 764 | 0.225 | 0.3812 | Yes |
| 23 | APOA5 | APOA5 Entrez, Source | apolipoprotein A-V | 827 | 0.217 | 0.3873 | Yes |
| 24 | CEBPB | CEBPB Entrez, Source | CCAAT/enhancer binding protein (C/EBP), beta | 862 | 0.212 | 0.3952 | Yes |
| 25 | IRAK2 | IRAK2 Entrez, Source | interleukin-1 receptor-associated kinase 2 | 868 | 0.212 | 0.4053 | Yes |
| 26 | SIGIRR | SIGIRR Entrez, Source | single immunoglobulin and toll-interleukin 1 receptor (TIR) domain | 872 | 0.211 | 0.4155 | Yes |
| 27 | F12 | F12 Entrez, Source | coagulation factor XII (Hageman factor) | 970 | 0.198 | 0.4180 | Yes |
| 28 | IL1RAP | IL1RAP Entrez, Source | interleukin 1 receptor accessory protein | 1037 | 0.188 | 0.4223 | Yes |
| 29 | GNA12 | GNA12 Entrez, Source | guanine nucleotide binding protein (G protein) alpha 12 | 1290 | 0.165 | 0.4114 | Yes |
| 30 | CD40LG | CD40LG Entrez, Source | CD40 ligand (TNF superfamily, member 5, hyper-IgM syndrome) | 1443 | 0.154 | 0.4075 | Yes |
| 31 | CD97 | CD97 Entrez, Source | CD97 molecule | 1481 | 0.151 | 0.4122 | Yes |
| 32 | ADORA1 | ADORA1 Entrez, Source | adenosine A1 receptor | 1508 | 0.149 | 0.4176 | Yes |
| 33 | IL8RA | IL8RA Entrez, Source | interleukin 8 receptor, alpha | 1575 | 0.144 | 0.4198 | Yes |
| 34 | C3AR1 | C3AR1 Entrez, Source | complement component 3a receptor 1 | 1576 | 0.144 | 0.4269 | Yes |
| 35 | CXCL9 | CXCL9 Entrez, Source | chemokine (C-X-C motif) ligand 9 | 1860 | 0.128 | 0.4118 | No |
| 36 | TNFRSF1A | TNFRSF1A Entrez, Source | tumor necrosis factor receptor superfamily, member 1A | 1920 | 0.125 | 0.4136 | No |
| 37 | SERPINE1 | SERPINE1 Entrez, Source | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 1938 | 0.125 | 0.4185 | No |
| 38 | CCR1 | CCR1 Entrez, Source | chemokine (C-C motif) receptor 1 | 2108 | 0.117 | 0.4115 | No |
| 39 | HNF4A | HNF4A Entrez, Source | hepatocyte nuclear factor 4, alpha | 2205 | 0.114 | 0.4099 | No |
| 40 | PROS1 | PROS1 Entrez, Source | protein S (alpha) | 2217 | 0.114 | 0.4147 | No |
| 41 | ADORA3 | ADORA3 Entrez, Source | adenosine A3 receptor | 2254 | 0.112 | 0.4175 | No |
| 42 | LMAN1 | LMAN1 Entrez, Source | lectin, mannose-binding, 1 | 2405 | 0.106 | 0.4115 | No |
| 43 | TACR1 | TACR1 Entrez, Source | tachykinin receptor 1 | 2454 | 0.105 | 0.4130 | No |
| 44 | CCL11 | CCL11 Entrez, Source | chemokine (C-C motif) ligand 11 | 2556 | 0.101 | 0.4104 | No |
| 45 | APCS | APCS Entrez, Source | amyloid P component, serum | 2625 | 0.098 | 0.4101 | No |
| 46 | CX3CR1 | CX3CR1 Entrez, Source | chemokine (C-X3-C motif) receptor 1 | 2732 | 0.094 | 0.4067 | No |
| 47 | ACVRL1 | ACVRL1 Entrez, Source | activin A receptor type II-like 1 | 2768 | 0.093 | 0.4087 | No |
| 48 | CCL5 | CCL5 Entrez, Source | chemokine (C-C motif) ligand 5 | 2781 | 0.092 | 0.4124 | No |
| 49 | ADORA2A | ADORA2A Entrez, Source | adenosine A2a receptor | 3051 | 0.083 | 0.3961 | No |
| 50 | F13A1 | F13A1 Entrez, Source | coagulation factor XIII, A1 polypeptide | 3304 | 0.076 | 0.3808 | No |
| 51 | ORM1 | ORM1 Entrez, Source | orosomucoid 1 | 3328 | 0.075 | 0.3828 | No |
| 52 | GHSR | GHSR Entrez, Source | growth hormone secretagogue receptor | 3367 | 0.074 | 0.3836 | No |
| 53 | CCL22 | CCL22 Entrez, Source | chemokine (C-C motif) ligand 22 | 3377 | 0.074 | 0.3866 | No |
| 54 | PLA2G2D | PLA2G2D Entrez, Source | phospholipase A2, group IID | 3584 | 0.069 | 0.3744 | No |
| 55 | EREG | EREG Entrez, Source | epiregulin | 3625 | 0.068 | 0.3748 | No |
| 56 | GP9 | GP9 Entrez, Source | glycoprotein IX (platelet) | 3635 | 0.068 | 0.3775 | No |
| 57 | NFKB1 | NFKB1 Entrez, Source | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105) | 3646 | 0.068 | 0.3801 | No |
| 58 | IL1A | IL1A Entrez, Source | interleukin 1, alpha | 3784 | 0.064 | 0.3729 | No |
| 59 | AIF1 | AIF1 Entrez, Source | allograft inflammatory factor 1 | 3839 | 0.063 | 0.3719 | No |
| 60 | NMI | NMI Entrez, Source | N-myc (and STAT) interactor | 4163 | 0.056 | 0.3502 | No |
| 61 | ABCF1 | ABCF1 Entrez, Source | ATP-binding cassette, sub-family F (GCN20), member 1 | 4274 | 0.053 | 0.3446 | No |
| 62 | HDAC5 | HDAC5 Entrez, Source | histone deacetylase 5 | 4333 | 0.052 | 0.3428 | No |
| 63 | VWF | VWF Entrez, Source | von Willebrand factor | 4369 | 0.051 | 0.3426 | No |
| 64 | GAP43 | GAP43 Entrez, Source | growth associated protein 43 | 4520 | 0.048 | 0.3337 | No |
| 65 | CHRNA7 | CHRNA7 Entrez, Source | cholinergic receptor, nicotinic, alpha 7 | 4725 | 0.043 | 0.3204 | No |
| 66 | ALOX15 | ALOX15 Entrez, Source | arachidonate 15-lipoxygenase | 4728 | 0.043 | 0.3224 | No |
| 67 | AOC3 | AOC3 Entrez, Source | amine oxidase, copper containing 3 (vascular adhesion protein 1) | 4870 | 0.040 | 0.3137 | No |
| 68 | LTB4R | LTB4R Entrez, Source | leukotriene B4 receptor | 4960 | 0.039 | 0.3089 | No |
| 69 | ELF3 | ELF3 Entrez, Source | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | 5014 | 0.038 | 0.3067 | No |
| 70 | PRDX5 | PRDX5 Entrez, Source | peroxiredoxin 5 | 5059 | 0.037 | 0.3052 | No |
| 71 | IL13 | IL13 Entrez, Source | interleukin 13 | 5064 | 0.037 | 0.3068 | No |
| 72 | S100A9 | S100A9 Entrez, Source | S100 calcium binding protein A9 | 5107 | 0.036 | 0.3053 | No |
| 73 | CXCL10 | CXCL10 Entrez, Source | chemokine (C-X-C motif) ligand 10 | 5128 | 0.035 | 0.3056 | No |
| 74 | NFX1 | NFX1 Entrez, Source | nuclear transcription factor, X-box binding 1 | 5152 | 0.035 | 0.3056 | No |
| 75 | CXCR4 | CXCR4 Entrez, Source | chemokine (C-X-C motif) receptor 4 | 5204 | 0.034 | 0.3034 | No |
| 76 | IL5 | IL5 Entrez, Source | interleukin 5 (colony-stimulating factor, eosinophil) | 5207 | 0.034 | 0.3049 | No |
| 77 | AGER | AGER Entrez, Source | advanced glycosylation end product-specific receptor | 5500 | 0.028 | 0.2842 | No |
| 78 | IL8RB | IL8RB Entrez, Source | interleukin 8 receptor, beta | 5537 | 0.027 | 0.2828 | No |
| 79 | KLK8 | KLK8 Entrez, Source | kallikrein 8 (neuropsin/ovasin) | 5646 | 0.025 | 0.2759 | No |
| 80 | NFATC4 | NFATC4 Entrez, Source | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4 | 5709 | 0.024 | 0.2723 | No |
| 81 | CCR5 | CCR5 Entrez, Source | chemokine (C-C motif) receptor 5 | 5806 | 0.022 | 0.2662 | No |
| 82 | TFPI | TFPI Entrez, Source | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 5843 | 0.021 | 0.2645 | No |
| 83 | CCR2 | CCR2 Entrez, Source | chemokine (C-C motif) receptor 2 | 5861 | 0.021 | 0.2642 | No |
| 84 | FGF7 | FGF7 Entrez, Source | fibroblast growth factor 7 (keratinocyte growth factor) | 5913 | 0.020 | 0.2614 | No |
| 85 | PF4 | PF4 Entrez, Source | platelet factor 4 (chemokine (C-X-C motif) ligand 4) | 6018 | 0.018 | 0.2544 | No |
| 86 | ENTPD1 | ENTPD1 Entrez, Source | ectonucleoside triphosphate diphosphohydrolase 1 | 6257 | 0.013 | 0.2370 | No |
| 87 | SCG2 | SCG2 Entrez, Source | secretogranin II (chromogranin C) | 6564 | 0.007 | 0.2142 | No |
| 88 | NOX4 | NOX4 Entrez, Source | NADPH oxidase 4 | 6694 | 0.004 | 0.2046 | No |
| 89 | MEFV | MEFV Entrez, Source | Mediterranean fever | 7026 | -0.003 | 0.1797 | No |
| 90 | CCR3 | CCR3 Entrez, Source | chemokine (C-C motif) receptor 3 | 7177 | -0.006 | 0.1686 | No |
| 91 | AHSG | AHSG Entrez, Source | alpha-2-HS-glycoprotein | 7259 | -0.008 | 0.1629 | No |
| 92 | RELA | RELA Entrez, Source | v-rel reticuloendotheliosis viral oncogene homolog A, nuclear factor of kappa light polypeptide gene enhancer in B-cells 3, p65 (avian) | 7310 | -0.008 | 0.1595 | No |
| 93 | PABPC4 | PABPC4 Entrez, Source | poly(A) binding protein, cytoplasmic 4 (inducible form) | 7324 | -0.009 | 0.1590 | No |
| 94 | F2RL2 | F2RL2 Entrez, Source | coagulation factor II (thrombin) receptor-like 2 | 7411 | -0.011 | 0.1530 | No |
| 95 | F8 | F8 Entrez, Source | coagulation factor VIII, procoagulant component (hemophilia A) | 7497 | -0.012 | 0.1471 | No |
| 96 | CCR4 | CCR4 Entrez, Source | chemokine (C-C motif) receptor 4 | 7502 | -0.012 | 0.1475 | No |
| 97 | CCL4 | CCL4 Entrez, Source | chemokine (C-C motif) ligand 4 | 7592 | -0.014 | 0.1414 | No |
| 98 | F2RL3 | F2RL3 Entrez, Source | coagulation factor II (thrombin) receptor-like 3 | 7622 | -0.015 | 0.1400 | No |
| 99 | SOD1 | SOD1 Entrez, Source | superoxide dismutase 1, soluble (amyotrophic lateral sclerosis 1 (adult)) | 7856 | -0.020 | 0.1233 | No |
| 100 | GGCX | GGCX Entrez, Source | gamma-glutamyl carboxylase | 7862 | -0.020 | 0.1239 | No |
| 101 | F11R | F11R Entrez, Source | F11 receptor | 8090 | -0.025 | 0.1080 | No |
| 102 | AOX1 | AOX1 Entrez, Source | aldehyde oxidase 1 | 8449 | -0.033 | 0.0826 | No |
| 103 | CYBB | CYBB Entrez, Source | cytochrome b-245, beta polypeptide (chronic granulomatous disease) | 8513 | -0.035 | 0.0795 | No |
| 104 | GHRL | GHRL Entrez, Source | ghrelin/obestatin preprohormone | 8739 | -0.040 | 0.0644 | No |
| 105 | PTAFR | PTAFR Entrez, Source | platelet-activating factor receptor | 9097 | -0.049 | 0.0398 | No |
| 106 | PARP4 | PARP4 Entrez, Source | poly (ADP-ribose) polymerase family, member 4 | 9368 | -0.056 | 0.0222 | No |
| 107 | GNAQ | GNAQ Entrez, Source | guanine nucleotide binding protein (G protein), q polypeptide | 9655 | -0.064 | 0.0037 | No |
| 108 | RAC1 | RAC1 Entrez, Source | ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) | 9885 | -0.071 | -0.0101 | No |
| 109 | HRH1 | HRH1 Entrez, Source | histamine receptor H1 | 9893 | -0.071 | -0.0071 | No |
| 110 | SELE | SELE Entrez, Source | selectin E (endothelial adhesion molecule 1) | 9951 | -0.073 | -0.0078 | No |
| 111 | MDK | MDK Entrez, Source | midkine (neurite growth-promoting factor 2) | 9992 | -0.074 | -0.0071 | No |
| 112 | S100A8 | S100A8 Entrez, Source | S100 calcium binding protein A8 | 10280 | -0.084 | -0.0247 | No |
| 113 | RIPK2 | RIPK2 Entrez, Source | receptor-interacting serine-threonine kinase 2 | 10507 | -0.092 | -0.0372 | No |
| 114 | SCYE1 | SCYE1 Entrez, Source | small inducible cytokine subfamily E, member 1 (endothelial monocyte-activating) | 10959 | -0.110 | -0.0659 | No |
| 115 | CX3CL1 | CX3CL1 Entrez, Source | chemokine (C-X3-C motif) ligand 1 | 11035 | -0.114 | -0.0660 | No |
| 116 | LYZ | LYZ Entrez, Source | lysozyme (renal amyloidosis) | 11060 | -0.115 | -0.0621 | No |
| 117 | C2 | C2 Entrez, Source | complement component 2 | 11264 | -0.125 | -0.0713 | No |
| 118 | CTGF | CTGF Entrez, Source | connective tissue growth factor | 11278 | -0.125 | -0.0661 | No |
| 119 | DCBLD2 | DCBLD2 Entrez, Source | discoidin, CUB and LCCL domain containing 2 | 11288 | -0.126 | -0.0605 | No |
| 120 | NF1 | NF1 Entrez, Source | neurofibromin 1 (neurofibromatosis, von Recklinghausen disease, Watson disease) | 11321 | -0.127 | -0.0566 | No |
| 121 | CD59 | CD59 Entrez, Source | CD59 molecule, complement regulatory protein | 11683 | -0.149 | -0.0766 | No |
| 122 | BLNK | BLNK Entrez, Source | B-cell linker | 11704 | -0.150 | -0.0707 | No |
| 123 | HDAC7A | HDAC7A Entrez, Source | histone deacetylase 7A | 12032 | -0.176 | -0.0867 | No |
| 124 | THBD | THBD Entrez, Source | thrombomodulin | 12150 | -0.186 | -0.0864 | No |
| 125 | ADM | ADM Entrez, Source | adrenomedullin | 12796 | -0.285 | -0.1211 | No |
| 126 | TGFB2 | TGFB2 Entrez, Source | transforming growth factor, beta 2 | 12832 | -0.296 | -0.1091 | No |
| 127 | CXCL11 | CXCL11 Entrez, Source | chemokine (C-X-C motif) ligand 11 | 12838 | -0.299 | -0.0946 | No |
| 128 | PLAT | PLAT Entrez, Source | plasminogen activator, tissue | 13010 | -0.371 | -0.0892 | No |
| 129 | TGFB1 | TGFB1 Entrez, Source | transforming growth factor, beta 1 (Camurati-Engelmann disease) | 13047 | -0.395 | -0.0724 | No |
| 130 | F2R | F2R Entrez, Source | coagulation factor II (thrombin) receptor | 13270 | -0.762 | -0.0514 | No |
| 131 | ANXA1 | ANXA1 Entrez, Source | annexin A1 | 13327 | -1.146 | 0.0011 | No |
