Datasetdouble_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls
#double_gel_8d_versus_single_gel_8d.class.cls
#double_gel_8d_versus_single_gel_8d_repos
Phenotypeclass.cls#double_gel_8d_versus_single_gel_8d_repos
Upregulated in classsingle_gel_8d
GeneSetRUFFLE
Enrichment Score (ES)-0.6583836
Normalized Enrichment Score (NES)-1.687476
Nominal p-value0.017475728
FDR q-value0.07908601
FWER p-Value1.0
Table: GSEA Results Summary



Fig 1: Enrichment plot: RUFFLE   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

PROBEGENE SYMBOLGENE_TITLERANK IN GENE LISTRANK METRIC SCORERUNNING ESCORE ENRICHMENT
1PDPNPDPN
Entrez,  Source
podoplanin11690.174-0.0029No
2CDK6CDK6
Entrez,  Source
cyclin-dependent kinase 620670.119-0.0124No
3ARF6ARF6
Entrez,  Source
ADP-ribosylation factor 665610.007-0.3463No
4FGD4FGD4
Entrez,  Source
FYVE, RhoGEF and PH domain containing 46928-0.000-0.3736No
5PIB5PAPIB5PA
Entrez,  Source
phosphatidylinositol (4,5) bisphosphate 5-phosphatase, A7047-0.003-0.3810No
6ALS2ALS2
Entrez,  Source
amyotrophic lateral sclerosis 2 (juvenile)7100-0.004-0.3829No
7ARFIP2ARFIP2
Entrez,  Source
ADP-ribosylation factor interacting protein 2 (arfaptin 2)7224-0.007-0.3889No
8NME2NME2
Entrez,  Source
non-metastatic cells 2, protein (NM23B) expressed in7595-0.014-0.4096No
9CTTNCTTN
Entrez,  Source
cortactin10911-0.107-0.6061Yes
10BCAR1BCAR1
Entrez,  Source
breast cancer anti-estrogen resistance 111123-0.118-0.5643Yes
11TLN1TLN1
Entrez,  Source
talin 111127-0.118-0.5069Yes
12MYO5AMYO5A
Entrez,  Source
myosin VA (heavy chain 12, myoxin)11192-0.121-0.4528Yes
13ITGB1ITGB1
Entrez,  Source
integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)11366-0.129-0.4027Yes
14S100BS100B
Entrez,  Source
S100 calcium binding protein B11736-0.151-0.3567Yes
15FGD1FGD1
Entrez,  Source
FYVE, RhoGEF and PH domain containing 1 (faciogenital dysplasia)12106-0.182-0.2957Yes
16MYH9MYH9
Entrez,  Source
myosin, heavy chain 9, non-muscle12585-0.241-0.2140Yes
17S100A11S100A11
Entrez,  Source
S100 calcium binding protein A1112634-0.251-0.0954Yes
18S100A6S100A6
Entrez,  Source
S100 calcium binding protein A612854-0.3050.0366Yes
Table: GSEA details [plain text format]



Fig 2: RUFFLE   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet



Fig 3: RUFFLE: Random ES distribution   
Gene set null distribution of ES for RUFFLE