Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_single_gel_8d.class.cls #double_gel_8d_versus_single_gel_8d_repos |
| Phenotype | class.cls#double_gel_8d_versus_single_gel_8d_repos |
| Upregulated in class | double_gel_8d |
| GeneSet | SERINE_TYPE_PEPTIDASE_ACTIVITY |
| Enrichment Score (ES) | 0.6434402 |
| Normalized Enrichment Score (NES) | 1.9249995 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.0041964264 |
| FWER p-Value | 0.345 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | PLG | PLG Entrez, Source | plasminogen | 44 | 0.773 | 0.1172 | Yes |
| 2 | F10 | F10 Entrez, Source | coagulation factor X | 141 | 0.550 | 0.1957 | Yes |
| 3 | F9 | F9 Entrez, Source | coagulation factor IX (plasma thromboplastic component, Christmas disease, hemophilia B) | 203 | 0.468 | 0.2642 | Yes |
| 4 | PCSK6 | PCSK6 Entrez, Source | proprotein convertase subtilisin/kexin type 6 | 279 | 0.416 | 0.3234 | Yes |
| 5 | KLKB1 | KLKB1 Entrez, Source | kallikrein B, plasma (Fletcher factor) 1 | 297 | 0.399 | 0.3843 | Yes |
| 6 | MASP2 | MASP2 Entrez, Source | mannan-binding lectin serine peptidase 2 | 308 | 0.392 | 0.4447 | Yes |
| 7 | F2 | F2 Entrez, Source | coagulation factor II (thrombin) | 413 | 0.335 | 0.4891 | Yes |
| 8 | PROC | PROC Entrez, Source | protein C (inactivator of coagulation factors Va and VIIIa) | 476 | 0.310 | 0.5328 | Yes |
| 9 | PCSK9 | PCSK9 Entrez, Source | proprotein convertase subtilisin/kexin type 9 | 570 | 0.277 | 0.5690 | Yes |
| 10 | HGFAC | HGFAC Entrez, Source | HGF activator | 665 | 0.249 | 0.6009 | Yes |
| 11 | CFI | CFI Entrez, Source | complement factor I | 787 | 0.221 | 0.6262 | Yes |
| 12 | F12 | F12 Entrez, Source | coagulation factor XII (Hageman factor) | 970 | 0.198 | 0.6434 | Yes |
| 13 | PRSS1 | PRSS1 Entrez, Source | protease, serine, 1 (trypsin 1) | 1444 | 0.154 | 0.6319 | No |
| 14 | DPP4 | DPP4 Entrez, Source | dipeptidyl-peptidase 4 (CD26, adenosine deaminase complexing protein 2) | 1919 | 0.125 | 0.6158 | No |
| 15 | GZMB | GZMB Entrez, Source | granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1) | 2645 | 0.098 | 0.5766 | No |
| 16 | PRSS2 | PRSS2 Entrez, Source | protease, serine, 2 (trypsin 2) | 2681 | 0.096 | 0.5890 | No |
| 17 | GZMA | GZMA Entrez, Source | granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3) | 2776 | 0.093 | 0.5964 | No |
| 18 | CORIN | CORIN Entrez, Source | corin, serine peptidase | 2880 | 0.089 | 0.6024 | No |
| 19 | TOR1A | TOR1A Entrez, Source | torsin family 1, member A (torsin A) | 3215 | 0.078 | 0.5895 | No |
| 20 | ACR | ACR Entrez, Source | acrosin | 3640 | 0.068 | 0.5683 | No |
| 21 | CPD | CPD Entrez, Source | carboxypeptidase D | 4677 | 0.045 | 0.4974 | No |
| 22 | CFD | CFD Entrez, Source | complement factor D (adipsin) | 4814 | 0.042 | 0.4936 | No |
| 23 | KLK8 | KLK8 Entrez, Source | kallikrein 8 (neuropsin/ovasin) | 5646 | 0.025 | 0.4351 | No |
| 24 | PCSK2 | PCSK2 Entrez, Source | proprotein convertase subtilisin/kexin type 2 | 5915 | 0.020 | 0.4180 | No |
| 25 | APEH | APEH Entrez, Source | N-acylaminoacyl-peptide hydrolase | 7142 | -0.005 | 0.3267 | No |
| 26 | HTRA2 | HTRA2 Entrez, Source | HtrA serine peptidase 2 | 7406 | -0.010 | 0.3085 | No |
| 27 | PREP | PREP Entrez, Source | prolyl endopeptidase | 7731 | -0.017 | 0.2869 | No |
| 28 | C1R | C1R Entrez, Source | complement component 1, r subcomponent | 10987 | -0.111 | 0.0596 | No |
| 29 | TPP1 | TPP1 Entrez, Source | tripeptidyl peptidase I | 11989 | -0.172 | 0.0113 | No |
| 30 | TPP2 | TPP2 Entrez, Source | tripeptidyl peptidase II | 12117 | -0.183 | 0.0303 | No |
| 31 | HTRA1 | HTRA1 Entrez, Source | HtrA serine peptidase 1 | 12165 | -0.188 | 0.0561 | No |
| 32 | MASP1 | MASP1 Entrez, Source | mannan-binding lectin serine peptidase 1 (C4/C2 activating component of Ra-reactive factor) | 12320 | -0.207 | 0.0768 | No |
