Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_single_gel_8d.class.cls #double_gel_8d_versus_single_gel_8d_repos |
| Phenotype | class.cls#double_gel_8d_versus_single_gel_8d_repos |
| Upregulated in class | single_gel_8d |
| GeneSet | SERUM_FIBROBLAST_CELLCYCLE |
| Enrichment Score (ES) | -0.66978645 |
| Normalized Enrichment Score (NES) | -2.155925 |
| Nominal p-value | 0.0 |
| FDR q-value | 8.400714E-4 |
| FWER p-Value | 0.0060 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | DHFR | DHFR Entrez, Source | dihydrofolate reductase | 457 | 0.317 | -0.0024 | No |
| 2 | AMD1 | AMD1 Entrez, Source | adenosylmethionine decarboxylase 1 | 1608 | 0.143 | -0.0745 | No |
| 3 | LYAR | LYAR Entrez, Source | - | 2462 | 0.104 | -0.1282 | No |
| 4 | CCNF | CCNF Entrez, Source | cyclin F | 3166 | 0.080 | -0.1731 | No |
| 5 | CDC25A | CDC25A Entrez, Source | cell division cycle 25A | 4801 | 0.042 | -0.2918 | No |
| 6 | BARD1 | BARD1 Entrez, Source | BRCA1 associated RING domain 1 | 5278 | 0.032 | -0.3244 | No |
| 7 | RANGAP1 | RANGAP1 Entrez, Source | Ran GTPase activating protein 1 | 6082 | 0.017 | -0.3831 | No |
| 8 | MAPK13 | MAPK13 Entrez, Source | mitogen-activated protein kinase 13 | 6324 | 0.011 | -0.4001 | No |
| 9 | DONSON | DONSON Entrez, Source | downstream neighbor of SON | 6326 | 0.011 | -0.3990 | No |
| 10 | PAQR4 | PAQR4 Entrez, Source | progestin and adipoQ receptor family member IV | 6650 | 0.005 | -0.4228 | No |
| 11 | TOP2A | TOP2A Entrez, Source | topoisomerase (DNA) II alpha 170kDa | 6709 | 0.004 | -0.4268 | No |
| 12 | ABCC5 | ABCC5 Entrez, Source | ATP-binding cassette, sub-family C (CFTR/MRP), member 5 | 6790 | 0.003 | -0.4326 | No |
| 13 | WSB1 | WSB1 Entrez, Source | WD repeat and SOCS box-containing 1 | 7573 | -0.014 | -0.4900 | No |
| 14 | CASP3 | CASP3 Entrez, Source | caspase 3, apoptosis-related cysteine peptidase | 8700 | -0.039 | -0.5708 | No |
| 15 | SPAG5 | SPAG5 Entrez, Source | sperm associated antigen 5 | 9056 | -0.048 | -0.5927 | No |
| 16 | TUBB2C | TUBB2C Entrez, Source | tubulin, beta 2C | 9110 | -0.049 | -0.5918 | No |
| 17 | CDKN3 | CDKN3 Entrez, Source | cyclin-dependent kinase inhibitor 3 (CDK2-associated dual specificity phosphatase) | 9252 | -0.053 | -0.5970 | No |
| 18 | USP1 | USP1 Entrez, Source | ubiquitin specific peptidase 1 | 9270 | -0.054 | -0.5929 | No |
| 19 | FBXL20 | FBXL20 Entrez, Source | F-box and leucine-rich repeat protein 20 | 9357 | -0.056 | -0.5937 | No |
| 20 | CIITA | CIITA Entrez, Source | class II, major histocompatibility complex, transactivator | 9491 | -0.060 | -0.5977 | No |
| 21 | SDC1 | SDC1 Entrez, Source | syndecan 1 | 9762 | -0.067 | -0.6113 | No |
| 22 | YWHAH | YWHAH Entrez, Source | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide | 9794 | -0.068 | -0.6068 | No |
| 23 | KIFC1 | KIFC1 Entrez, Source | kinesin family member C1 | 10247 | -0.083 | -0.6324 | No |
| 24 | PLK1 | PLK1 Entrez, Source | polo-like kinase 1 (Drosophila) | 10276 | -0.084 | -0.6261 | No |
| 25 | ANP32E | ANP32E Entrez, Source | acidic (leucine-rich) nuclear phosphoprotein 32 family, member E | 10400 | -0.088 | -0.6265 | No |
| 26 | PCNA | PCNA Entrez, Source | proliferating cell nuclear antigen | 10651 | -0.097 | -0.6355 | No |
| 27 | ADAMTS1 | ADAMTS1 Entrez, Source | ADAM metallopeptidase with thrombospondin type 1 motif, 1 | 10664 | -0.097 | -0.6266 | No |
| 28 | FOXM1 | FOXM1 Entrez, Source | forkhead box M1 | 10847 | -0.105 | -0.6297 | No |
| 29 | CDCA7 | CDCA7 Entrez, Source | cell division cycle associated 7 | 11253 | -0.124 | -0.6476 | No |
| 30 | LMNB1 | LMNB1 Entrez, Source | lamin B1 | 11329 | -0.128 | -0.6404 | No |
| 31 | PTTG1 | PTTG1 Entrez, Source | pituitary tumor-transforming 1 | 11624 | -0.145 | -0.6479 | No |
| 32 | SMC4 | SMC4 Entrez, Source | structural maintenance of chromosomes 4 | 11916 | -0.167 | -0.6530 | Yes |
| 33 | RFC2 | RFC2 Entrez, Source | replication factor C (activator 1) 2, 40kDa | 11987 | -0.172 | -0.6409 | Yes |
| 34 | TYMS | TYMS Entrez, Source | thymidylate synthetase | 12013 | -0.174 | -0.6252 | Yes |
| 35 | CDCA1 | CDCA1 Entrez, Source | cell division cycle associated 1 | 12173 | -0.189 | -0.6181 | Yes |
| 36 | PRIM2A | PRIM2A Entrez, Source | primase, polypeptide 2A, 58kDa | 12498 | -0.229 | -0.6195 | Yes |
| 37 | H2AFX | H2AFX Entrez, Source | H2A histone family, member X | 12504 | -0.229 | -0.5967 | Yes |
| 38 | AURKA | AURKA Entrez, Source | aurora kinase A | 12548 | -0.235 | -0.5762 | Yes |
| 39 | HMMR | HMMR Entrez, Source | hyaluronan-mediated motility receptor (RHAMM) | 12560 | -0.237 | -0.5531 | Yes |
| 40 | TACC3 | TACC3 Entrez, Source | transforming, acidic coiled-coil containing protein 3 | 12687 | -0.262 | -0.5362 | Yes |
| 41 | FEN1 | FEN1 Entrez, Source | flap structure-specific endonuclease 1 | 12720 | -0.269 | -0.5115 | Yes |
| 42 | TRIP13 | TRIP13 Entrez, Source | thyroid hormone receptor interactor 13 | 12822 | -0.294 | -0.4894 | Yes |
| 43 | MET | MET Entrez, Source | met proto-oncogene (hepatocyte growth factor receptor) | 12926 | -0.331 | -0.4638 | Yes |
| 44 | CDCA8 | CDCA8 Entrez, Source | cell division cycle associated 8 | 12936 | -0.334 | -0.4308 | Yes |
| 45 | CCNB2 | CCNB2 Entrez, Source | cyclin B2 | 12954 | -0.340 | -0.3978 | Yes |
| 46 | TUBB | TUBB Entrez, Source | tubulin, beta | 12961 | -0.344 | -0.3635 | Yes |
| 47 | PRIM1 | PRIM1 Entrez, Source | primase, polypeptide 1, 49kDa | 12999 | -0.364 | -0.3295 | Yes |
| 48 | HN1 | HN1 Entrez, Source | hematological and neurological expressed 1 | 13064 | -0.406 | -0.2934 | Yes |
| 49 | KIAA0101 | KIAA0101 Entrez, Source | KIAA0101 | 13128 | -0.448 | -0.2530 | Yes |
| 50 | ANKRD10 | ANKRD10 Entrez, Source | ankyrin repeat domain 10 | 13209 | -0.577 | -0.2008 | Yes |
| 51 | TIMP1 | TIMP1 Entrez, Source | TIMP metallopeptidase inhibitor 1 | 13213 | -0.582 | -0.1423 | Yes |
| 52 | CCNA2 | CCNA2 Entrez, Source | cyclin A2 | 13247 | -0.677 | -0.0765 | Yes |
| 53 | MCM6 | MCM6 Entrez, Source | MCM6 minichromosome maintenance deficient 6 (MIS5 homolog, S. pombe) (S. cerevisiae) | 13289 | -0.828 | 0.0040 | Yes |
