Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_single_gel_8d.class.cls #double_gel_8d_versus_single_gel_8d_repos |
| Phenotype | class.cls#double_gel_8d_versus_single_gel_8d_repos |
| Upregulated in class | double_gel_8d |
| GeneSet | SMITH_HCV_INDUCED_HCC_UP |
| Enrichment Score (ES) | 0.6083283 |
| Normalized Enrichment Score (NES) | 1.6223508 |
| Nominal p-value | 0.022916667 |
| FDR q-value | 0.059331317 |
| FWER p-Value | 1.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | GSTM4 | GSTM4 Entrez, Source | glutathione S-transferase M4 | 151 | 0.530 | 0.1489 | Yes |
| 2 | ACACA | ACACA Entrez, Source | acetyl-Coenzyme A carboxylase alpha | 154 | 0.527 | 0.3080 | Yes |
| 3 | FDPS | FDPS Entrez, Source | farnesyl diphosphate synthase (farnesyl pyrophosphate synthetase, dimethylallyltranstransferase, geranyltranstransferase) | 315 | 0.386 | 0.4125 | Yes |
| 4 | PMVK | PMVK Entrez, Source | phosphomevalonate kinase | 452 | 0.319 | 0.4988 | Yes |
| 5 | AMACR | AMACR Entrez, Source | alpha-methylacyl-CoA racemase | 533 | 0.289 | 0.5802 | Yes |
| 6 | SDC2 | SDC2 Entrez, Source | syndecan 2 (heparan sulfate proteoglycan 1, cell surface-associated, fibroglycan) | 960 | 0.199 | 0.6083 | Yes |
| 7 | PIR | PIR Entrez, Source | pirin (iron-binding nuclear protein) | 1602 | 0.143 | 0.6034 | No |
| 8 | BCL2 | BCL2 Entrez, Source | B-cell CLL/lymphoma 2 | 2467 | 0.104 | 0.5700 | No |
| 9 | DDC | DDC Entrez, Source | dopa decarboxylase (aromatic L-amino acid decarboxylase) | 3130 | 0.081 | 0.5447 | No |
| 10 | IMPA2 | IMPA2 Entrez, Source | inositol(myo)-1(or 4)-monophosphatase 2 | 3887 | 0.062 | 0.5068 | No |
| 11 | SDHC | SDHC Entrez, Source | succinate dehydrogenase complex, subunit C, integral membrane protein, 15kDa | 3898 | 0.062 | 0.5248 | No |
| 12 | TBX3 | TBX3 Entrez, Source | T-box 3 (ulnar mammary syndrome) | 4143 | 0.056 | 0.5235 | No |
| 13 | PXMP3 | PXMP3 Entrez, Source | peroxisomal membrane protein 3, 35kDa (Zellweger syndrome) | 4472 | 0.049 | 0.5136 | No |
| 14 | TOP2A | TOP2A Entrez, Source | topoisomerase (DNA) II alpha 170kDa | 6709 | 0.004 | 0.3469 | No |
| 15 | COPS5 | COPS5 Entrez, Source | COP9 constitutive photomorphogenic homolog subunit 5 (Arabidopsis) | 8889 | -0.043 | 0.1964 | No |
| 16 | CDKN3 | CDKN3 Entrez, Source | cyclin-dependent kinase inhibitor 3 (CDK2-associated dual specificity phosphatase) | 9252 | -0.053 | 0.1852 | No |
| 17 | NCOA2 | NCOA2 Entrez, Source | nuclear receptor coactivator 2 | 9531 | -0.061 | 0.1827 | No |
| 18 | ANXA7 | ANXA7 Entrez, Source | annexin A7 | 9552 | -0.061 | 0.1996 | No |
| 19 | GSTA4 | GSTA4 Entrez, Source | glutathione S-transferase A4 | 9961 | -0.073 | 0.1912 | No |
| 20 | TOB1 | TOB1 Entrez, Source | transducer of ERBB2, 1 | 10157 | -0.080 | 0.2008 | No |
| 21 | TBCE | TBCE Entrez, Source | tubulin-specific chaperone e | 11303 | -0.127 | 0.1531 | No |
