Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_single_gel_8d.class.cls #double_gel_8d_versus_single_gel_8d_repos |
| Phenotype | class.cls#double_gel_8d_versus_single_gel_8d_repos |
| Upregulated in class | double_gel_8d |
| GeneSet | STATIN_PATHWAY_PHARMGKB |
| Enrichment Score (ES) | 0.62675893 |
| Normalized Enrichment Score (NES) | 1.6239301 |
| Nominal p-value | 0.014256619 |
| FDR q-value | 0.058908287 |
| FWER p-Value | 1.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | APOC1 | APOC1 Entrez, Source | apolipoprotein C-I | 36 | 0.809 | 0.1583 | Yes |
| 2 | LCAT | LCAT Entrez, Source | lecithin-cholesterol acyltransferase | 76 | 0.677 | 0.2901 | Yes |
| 3 | APOA4 | APOA4 Entrez, Source | apolipoprotein A-IV | 96 | 0.620 | 0.4121 | Yes |
| 4 | LPL | LPL Entrez, Source | lipoprotein lipase | 230 | 0.451 | 0.4920 | Yes |
| 5 | HMGCR | HMGCR Entrez, Source | 3-hydroxy-3-methylglutaryl-Coenzyme A reductase | 434 | 0.327 | 0.5418 | Yes |
| 6 | LDLR | LDLR Entrez, Source | low density lipoprotein receptor (familial hypercholesterolemia) | 592 | 0.270 | 0.5838 | Yes |
| 7 | CYP7A1 | CYP7A1 Entrez, Source | cytochrome P450, family 7, subfamily A, polypeptide 1 | 934 | 0.202 | 0.5983 | Yes |
| 8 | APOA1 | APOA1 Entrez, Source | apolipoprotein A-I | 1052 | 0.187 | 0.6268 | Yes |
| 9 | APOC3 | APOC3 Entrez, Source | apolipoprotein C-III | 1478 | 0.151 | 0.6249 | No |
| 10 | DGAT1 | DGAT1 Entrez, Source | diacylglycerol O-acyltransferase homolog 1 (mouse) | 1822 | 0.130 | 0.6250 | No |
| 11 | SCARB1 | SCARB1 Entrez, Source | scavenger receptor class B, member 1 | 2252 | 0.112 | 0.6152 | No |
| 12 | APOE | APOE Entrez, Source | apolipoprotein E | 5056 | 0.037 | 0.4122 | No |
| 13 | LRP1 | LRP1 Entrez, Source | low density lipoprotein-related protein 1 (alpha-2-macroglobulin receptor) | 8598 | -0.037 | 0.1539 | No |
| 14 | ABCA1 | ABCA1 Entrez, Source | ATP-binding cassette, sub-family A (ABC1), member 1 | 12519 | -0.231 | -0.0943 | No |
| 15 | SOAT1 | SOAT1 Entrez, Source | sterol O-acyltransferase (acyl-Coenzyme A: cholesterol acyltransferase) 1 | 12979 | -0.351 | -0.0589 | No |
| 16 | LIPC | LIPC Entrez, Source | lipase, hepatic | 13109 | -0.433 | 0.0175 | No |
