Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_single_gel_8d.class.cls #double_gel_8d_versus_single_gel_8d_repos |
| Phenotype | class.cls#double_gel_8d_versus_single_gel_8d_repos |
| Upregulated in class | double_gel_8d |
| GeneSet | STEROID_BIOSYNTHETIC_PROCESS |
| Enrichment Score (ES) | 0.6656537 |
| Normalized Enrichment Score (NES) | 1.7408472 |
| Nominal p-value | 0.0040816325 |
| FDR q-value | 0.022634212 |
| FWER p-Value | 0.99 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | DHCR24 | DHCR24 Entrez, Source | 24-dehydrocholesterol reductase | 282 | 0.412 | 0.1090 | Yes |
| 2 | HSD3B1 | HSD3B1 Entrez, Source | hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 | 293 | 0.402 | 0.2352 | Yes |
| 3 | FDPS | FDPS Entrez, Source | farnesyl diphosphate synthase (farnesyl pyrophosphate synthetase, dimethylallyltranstransferase, geranyltranstransferase) | 315 | 0.386 | 0.3554 | Yes |
| 4 | DHCR7 | DHCR7 Entrez, Source | 7-dehydrocholesterol reductase | 333 | 0.375 | 0.4728 | Yes |
| 5 | SCP2 | SCP2 Entrez, Source | sterol carrier protein 2 | 624 | 0.260 | 0.5331 | Yes |
| 6 | AKR1D1 | AKR1D1 Entrez, Source | aldo-keto reductase family 1, member D1 (delta 4-3-ketosteroid-5-beta-reductase) | 656 | 0.251 | 0.6102 | Yes |
| 7 | NSDHL | NSDHL Entrez, Source | NAD(P) dependent steroid dehydrogenase-like | 829 | 0.216 | 0.6657 | Yes |
| 8 | BMP6 | BMP6 Entrez, Source | bone morphogenetic protein 6 | 1653 | 0.140 | 0.6480 | No |
| 9 | CYP19A1 | CYP19A1 Entrez, Source | cytochrome P450, family 19, subfamily A, polypeptide 1 | 2909 | 0.088 | 0.5816 | No |
| 10 | NR0B1 | NR0B1 Entrez, Source | nuclear receptor subfamily 0, group B, member 1 | 4557 | 0.047 | 0.4729 | No |
| 11 | HSD11B2 | HSD11B2 Entrez, Source | hydroxysteroid (11-beta) dehydrogenase 2 | 6111 | 0.016 | 0.3614 | No |
| 12 | CYP7B1 | CYP7B1 Entrez, Source | cytochrome P450, family 7, subfamily B, polypeptide 1 | 7432 | -0.011 | 0.2658 | No |
| 13 | SOD1 | SOD1 Entrez, Source | superoxide dismutase 1, soluble (amyotrophic lateral sclerosis 1 (adult)) | 7856 | -0.020 | 0.2403 | No |
| 14 | FDXR | FDXR Entrez, Source | ferredoxin reductase | 7908 | -0.021 | 0.2432 | No |
| 15 | HSD3B7 | HSD3B7 Entrez, Source | hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7 | 8334 | -0.031 | 0.2211 | No |
| 16 | CNBP | CNBP Entrez, Source | CCHC-type zinc finger, nucleic acid binding protein | 9302 | -0.054 | 0.1657 | No |
| 17 | CYP11A1 | CYP11A1 Entrez, Source | cytochrome P450, family 11, subfamily A, polypeptide 1 | 11705 | -0.150 | 0.0328 | No |
| 18 | ADM | ADM Entrez, Source | adrenomedullin | 12796 | -0.285 | 0.0410 | No |
