Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_single_gel_8d.class.cls #double_gel_8d_versus_single_gel_8d_repos |
| Phenotype | class.cls#double_gel_8d_versus_single_gel_8d_repos |
| Upregulated in class | single_gel_8d |
| GeneSet | STRIATED_MUSCLE_CONTRACTION |
| Enrichment Score (ES) | -0.60147685 |
| Normalized Enrichment Score (NES) | -1.6806706 |
| Nominal p-value | 0.0059288535 |
| FDR q-value | 0.080778934 |
| FWER p-Value | 1.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | MYH6 /// MYH7 | 619 | 0.260 | 0.0115 | No | ||
| 2 | TNNT1 | TNNT1 Entrez, Source | troponin T type 1 (skeletal, slow) | 1040 | 0.188 | 0.0218 | No |
| 3 | MYL3 | MYL3 Entrez, Source | myosin, light chain 3, alkali; ventricular, skeletal, slow | 1844 | 0.129 | -0.0097 | No |
| 4 | TNNT3 | TNNT3 Entrez, Source | troponin T type 3 (skeletal, fast) | 2118 | 0.117 | -0.0041 | No |
| 5 | DMD | DMD Entrez, Source | dystrophin (muscular dystrophy, Duchenne and Becker types) | 2146 | 0.116 | 0.0197 | No |
| 6 | TNNI2 | TNNI2 Entrez, Source | troponin I type 2 (skeletal, fast) | 3007 | 0.085 | -0.0260 | No |
| 7 | MYH6 | MYH6 Entrez, Source | myosin, heavy chain 6, cardiac muscle, alpha (cardiomyopathy, hypertrophic 1) | 3603 | 0.069 | -0.0554 | No |
| 8 | MYH3 | MYH3 Entrez, Source | myosin, heavy chain 3, skeletal muscle, embryonic | 3820 | 0.064 | -0.0574 | No |
| 9 | MYH8 | MYH8 Entrez, Source | myosin, heavy chain 8, skeletal muscle, perinatal | 4145 | 0.056 | -0.0692 | No |
| 10 | TNNI3 | TNNI3 Entrez, Source | troponin I type 3 (cardiac) | 4196 | 0.055 | -0.0607 | No |
| 11 | TTN | TTN Entrez, Source | titin | 4401 | 0.050 | -0.0648 | No |
| 12 | TNNT2 | TNNT2 Entrez, Source | troponin T type 2 (cardiac) | 4572 | 0.047 | -0.0671 | No |
| 13 | ACTN3 | ACTN3 Entrez, Source | actinin, alpha 3 | 5159 | 0.035 | -0.1033 | No |
| 14 | TNNI1 | TNNI1 Entrez, Source | troponin I type 1 (skeletal, slow) | 5503 | 0.028 | -0.1229 | No |
| 15 | MYL2 | MYL2 Entrez, Source | myosin, light chain 2, regulatory, cardiac, slow | 6293 | 0.012 | -0.1794 | No |
| 16 | MYBPC1 | MYBPC1 Entrez, Source | myosin binding protein C, slow type | 7017 | -0.002 | -0.2332 | No |
| 17 | TMOD1 | TMOD1 Entrez, Source | tropomodulin 1 | 7618 | -0.015 | -0.2749 | No |
| 18 | MYOM1 | MYOM1 Entrez, Source | myomesin 1 (skelemin) 185kDa | 8685 | -0.039 | -0.3464 | No |
| 19 | DES | DES Entrez, Source | desmin | 8928 | -0.044 | -0.3547 | No |
| 20 | ACTA2 | ACTA2 Entrez, Source | actin, alpha 2, smooth muscle, aorta | 12216 | -0.193 | -0.5584 | Yes |
| 21 | ACTN4 | ACTN4 Entrez, Source | actinin, alpha 4 | 12269 | -0.201 | -0.5175 | Yes |
| 22 | TPM4 | TPM4 Entrez, Source | tropomyosin 4 | 12551 | -0.235 | -0.4861 | Yes |
| 23 | TPM1 | TPM1 Entrez, Source | tropomyosin 1 (alpha) | 12998 | -0.364 | -0.4385 | Yes |
| 24 | VIM | VIM Entrez, Source | vimentin | 13164 | -0.501 | -0.3391 | Yes |
| 25 | ACTA1 | ACTA1 Entrez, Source | actin, alpha 1, skeletal muscle | 13340 | -1.581 | 0.0002 | Yes |
