Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_single_gel_8d.class.cls #double_gel_8d_versus_single_gel_8d_repos |
| Phenotype | class.cls#double_gel_8d_versus_single_gel_8d_repos |
| Upregulated in class | single_gel_8d |
| GeneSet | STRUCTURAL_CONSTITUENT_OF_CYTOSKELETON |
| Enrichment Score (ES) | -0.7028133 |
| Normalized Enrichment Score (NES) | -1.8808049 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.025392404 |
| FWER p-Value | 0.56 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | ANK1 | ANK1 Entrez, Source | ankyrin 1, erythrocytic | 525 | 0.292 | 0.0121 | No |
| 2 | SPTBN4 | SPTBN4 Entrez, Source | spectrin, beta, non-erythrocytic 4 | 1651 | 0.140 | -0.0477 | No |
| 3 | DMD | DMD Entrez, Source | dystrophin (muscular dystrophy, Duchenne and Becker types) | 2146 | 0.116 | -0.0643 | No |
| 4 | MAPT | MAPT Entrez, Source | microtubule-associated protein tau | 4812 | 0.042 | -0.2570 | No |
| 5 | BFSP1 | BFSP1 Entrez, Source | beaded filament structural protein 1, filensin | 8014 | -0.024 | -0.4931 | No |
| 6 | SORBS3 | SORBS3 Entrez, Source | sorbin and SH3 domain containing 3 | 8634 | -0.037 | -0.5330 | No |
| 7 | DES | DES Entrez, Source | desmin | 8928 | -0.044 | -0.5472 | No |
| 8 | HIP1 | HIP1 Entrez, Source | huntingtin interacting protein 1 | 9098 | -0.049 | -0.5513 | No |
| 9 | GFAP | GFAP Entrez, Source | glial fibrillary acidic protein | 9126 | -0.049 | -0.5446 | No |
| 10 | ACTL7B | ACTL7B Entrez, Source | actin-like 7B | 9475 | -0.059 | -0.5604 | No |
| 11 | ARPC5 | ARPC5 Entrez, Source | actin related protein 2/3 complex, subunit 5, 16kDa | 9496 | -0.060 | -0.5514 | No |
| 12 | TUBG1 | TUBG1 Entrez, Source | tubulin, gamma 1 | 9827 | -0.069 | -0.5639 | No |
| 13 | ADD3 | ADD3 Entrez, Source | adducin 3 (gamma) | 10162 | -0.080 | -0.5749 | No |
| 14 | ARPC1B | ARPC1B Entrez, Source | actin related protein 2/3 complex, subunit 1B, 41kDa | 10374 | -0.087 | -0.5753 | No |
| 15 | ACTB | ACTB Entrez, Source | actin, beta | 10590 | -0.095 | -0.5748 | No |
| 16 | SORBS2 | SORBS2 Entrez, Source | sorbin and SH3 domain containing 2 | 12297 | -0.204 | -0.6668 | Yes |
| 17 | DSP | DSP Entrez, Source | desmoplakin | 12592 | -0.244 | -0.6459 | Yes |
| 18 | VIM | VIM Entrez, Source | vimentin | 13164 | -0.501 | -0.6004 | Yes |
| 19 | MSN | MSN Entrez, Source | moesin | 13302 | -0.941 | -0.4448 | Yes |
| 20 | NEFL | NEFL Entrez, Source | neurofilament, light polypeptide 68kDa | 13304 | -0.959 | -0.2759 | Yes |
| 21 | ACTA1 | ACTA1 Entrez, Source | actin, alpha 1, skeletal muscle | 13340 | -1.581 | 0.0002 | Yes |
