Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_single_gel_8d.class.cls #double_gel_8d_versus_single_gel_8d_repos |
Phenotype | class.cls#double_gel_8d_versus_single_gel_8d_repos |
Upregulated in class | single_gel_8d |
GeneSet | STRUCTURAL_MOLECULE_ACTIVITY |
Enrichment Score (ES) | -0.44052064 |
Normalized Enrichment Score (NES) | -1.6322314 |
Nominal p-value | 0.0017889087 |
FDR q-value | 0.10332504 |
FWER p-Value | 1.0 |
PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|---|
1 | CORO1A | CORO1A Entrez,  Source | coronin, actin binding protein, 1A | 136 | 0.556 | 0.0272 | No |
2 | ANK1 | ANK1 Entrez,  Source | ankyrin 1, erythrocytic | 525 | 0.292 | 0.0175 | No |
3 | MYBPH | MYBPH Entrez,  Source | myosin binding protein H | 919 | 0.204 | 0.0015 | No |
4 | MAL | MAL Entrez,  Source | mal, T-cell differentiation protein | 1572 | 0.144 | -0.0381 | No |
5 | SPTBN4 | SPTBN4 Entrez,  Source | spectrin, beta, non-erythrocytic 4 | 1651 | 0.140 | -0.0346 | No |
6 | MATN1 | MATN1 Entrez,  Source | matrilin 1, cartilage matrix protein | 1702 | 0.137 | -0.0292 | No |
7 | MYL3 | MYL3 Entrez,  Source | myosin, light chain 3, alkali; ventricular, skeletal, slow | 1844 | 0.129 | -0.0311 | No |
8 | MRPL12 | MRPL12 Entrez,  Source | mitochondrial ribosomal protein L12 | 1940 | 0.124 | -0.0300 | No |
9 | DMD | DMD Entrez,  Source | dystrophin (muscular dystrophy, Duchenne and Becker types) | 2146 | 0.116 | -0.0376 | No |
10 | FBN2 | FBN2 Entrez,  Source | fibrillin 2 (congenital contractural arachnodactyly) | 2408 | 0.106 | -0.0502 | No |
11 | DSPP | DSPP Entrez,  Source | dentin sialophosphoprotein | 2418 | 0.106 | -0.0438 | No |
12 | BFAR | BFAR Entrez,  Source | bifunctional apoptosis regulator | 3241 | 0.077 | -0.1008 | No |
13 | MRPL41 | MRPL41 Entrez,  Source | mitochondrial ribosomal protein L41 | 3347 | 0.075 | -0.1037 | No |
14 | MYH6 | MYH6 Entrez,  Source | myosin, heavy chain 6, cardiac muscle, alpha (cardiomyopathy, hypertrophic 1) | 3603 | 0.069 | -0.1183 | No |
15 | MAPK8IP2 | MAPK8IP2 Entrez,  Source | mitogen-activated protein kinase 8 interacting protein 2 | 3638 | 0.068 | -0.1163 | No |
16 | MRPS7 | MRPS7 Entrez,  Source | mitochondrial ribosomal protein S7 | 3745 | 0.065 | -0.1200 | No |
17 | IMPG1 | IMPG1 Entrez,  Source | interphotoreceptor matrix proteoglycan 1 | 3796 | 0.064 | -0.1194 | No |
18 | FBN1 | FBN1 Entrez,  Source | fibrillin 1 | 4122 | 0.057 | -0.1402 | No |
19 | MEPE | MEPE Entrez,  Source | matrix, extracellular phosphoglycoprotein with ASARM motif (bone) | 4322 | 0.052 | -0.1517 | No |
20 | TTN | TTN Entrez,  Source | titin | 4401 | 0.050 | -0.1543 | No |
21 | RPL21 | RPL21 Entrez,  Source | ribosomal protein L21 | 4790 | 0.042 | -0.1808 | No |
22 | MAPT | MAPT Entrez,  Source | microtubule-associated protein tau | 4812 | 0.042 | -0.1796 | No |
23 | CHI3L1 | CHI3L1 Entrez,  Source | chitinase 3-like 1 (cartilage glycoprotein-39) | 4937 | 0.039 | -0.1863 | No |
24 | ACTN3 | ACTN3 Entrez,  Source | actinin, alpha 3 | 5159 | 0.035 | -0.2007 | No |
25 | MYH11 | MYH11 Entrez,  Source | myosin, heavy chain 11, smooth muscle | 5315 | 0.032 | -0.2103 | No |
26 | TFPI2 | TFPI2 Entrez,  Source | tissue factor pathway inhibitor 2 | 5317 | 0.032 | -0.2082 | No |
27 | COMP | COMP Entrez,  Source | cartilage oligomeric matrix protein | 5328 | 0.031 | -0.2069 | No |
28 | IMPG2 | IMPG2 Entrez,  Source | interphotoreceptor matrix proteoglycan 2 | 5572 | 0.026 | -0.2235 | No |
29 | MYOC | MYOC Entrez,  Source | myocilin, trabecular meshwork inducible glucocorticoid response | 6067 | 0.017 | -0.2597 | No |
30 | MYL2 | MYL2 Entrez,  Source | myosin, light chain 2, regulatory, cardiac, slow | 6293 | 0.012 | -0.2759 | No |
31 | MYBPC1 | MYBPC1 Entrez,  Source | myosin binding protein C, slow type | 7017 | -0.002 | -0.3305 | No |
32 | RPL41 | RPL41 Entrez,  Source | ribosomal protein L41 | 7088 | -0.004 | -0.3355 | No |
33 | RPL35 | RPL35 Entrez,  Source | ribosomal protein L35 | 7279 | -0.008 | -0.3494 | No |
34 | COL4A4 | COL4A4 Entrez,  Source | collagen, type IV, alpha 4 | 7382 | -0.010 | -0.3564 | No |
35 | RPS29 | RPS29 Entrez,  Source | ribosomal protein S29 | 7396 | -0.010 | -0.3567 | No |
36 | RPL26 | RPL26 Entrez,  Source | ribosomal protein L26 | 7410 | -0.010 | -0.3570 | No |
37 | RPL37 | RPL37 Entrez,  Source | ribosomal protein L37 | 7466 | -0.012 | -0.3604 | No |
38 | RPL39 | RPL39 Entrez,  Source | ribosomal protein L39 | 7472 | -0.012 | -0.3600 | No |
39 | RPS18 | RPS18 Entrez,  Source | ribosomal protein S18 | 7553 | -0.014 | -0.3651 | No |
40 | MRPL23 | MRPL23 Entrez,  Source | mitochondrial ribosomal protein L23 | 7650 | -0.016 | -0.3713 | No |
41 | PRELP | PRELP Entrez,  Source | proline/arginine-rich end leucine-rich repeat protein | 7654 | -0.016 | -0.3705 | No |
42 | IVL | IVL Entrez,  Source | involucrin | 7745 | -0.018 | -0.3761 | No |
43 | RPS6 | RPS6 Entrez,  Source | ribosomal protein S6 | 7800 | -0.019 | -0.3790 | No |
44 | MYH7 | MYH7 Entrez,  Source | myosin, heavy chain 7, cardiac muscle, beta | 7898 | -0.021 | -0.3849 | No |
45 | RPS25 | RPS25 Entrez,  Source | ribosomal protein S25 | 8011 | -0.024 | -0.3918 | No |
46 | BFSP1 | BFSP1 Entrez,  Source | beaded filament structural protein 1, filensin | 8014 | -0.024 | -0.3903 | No |
47 | RPS20 | RPS20 Entrez,  Source | ribosomal protein S20 | 8019 | -0.024 | -0.3890 | No |
48 | RPLP1 | RPLP1 Entrez,  Source | ribosomal protein, large, P1 | 8028 | -0.024 | -0.3880 | No |
49 | RPL3 | RPL3 Entrez,  Source | ribosomal protein L3 | 8109 | -0.026 | -0.3923 | No |
50 | RPL4 | RPL4 Entrez,  Source | ribosomal protein L4 | 8146 | -0.026 | -0.3933 | No |
51 | RPL31 | RPL31 Entrez,  Source | ribosomal protein L31 | 8192 | -0.027 | -0.3948 | No |
52 | RPL8 | RPL8 Entrez,  Source | ribosomal protein L8 | 8255 | -0.029 | -0.3976 | No |
53 | RPS24 | RPS24 Entrez,  Source | ribosomal protein S24 | 8294 | -0.030 | -0.3985 | No |
54 | RPL9 | RPL9 Entrez,  Source | ribosomal protein L9 | 8332 | -0.031 | -0.3992 | No |
55 | RPL24 | RPL24 Entrez,  Source | ribosomal protein L24 | 8338 | -0.031 | -0.3975 | No |
56 | RPS27 | RPS27 Entrez,  Source | ribosomal protein S27 (metallopanstimulin 1) | 8382 | -0.032 | -0.3986 | No |
57 | RPS3A | RPS3A Entrez,  Source | ribosomal protein S3A | 8514 | -0.035 | -0.4062 | No |
58 | RPL5 | RPL5 Entrez,  Source | ribosomal protein L5 | 8527 | -0.035 | -0.4047 | No |
59 | RPS13 | RPS13 Entrez,  Source | ribosomal protein S13 | 8611 | -0.037 | -0.4085 | No |
60 | RPL28 | RPL28 Entrez,  Source | ribosomal protein L28 | 8612 | -0.037 | -0.4060 | No |
61 | SORBS3 | SORBS3 Entrez,  Source | sorbin and SH3 domain containing 3 | 8634 | -0.037 | -0.4050 | No |
62 | RPL29 | RPL29 Entrez,  Source | ribosomal protein L29 | 8680 | -0.039 | -0.4059 | No |
63 | MYOM1 | MYOM1 Entrez,  Source | myomesin 1 (skelemin) 185kDa | 8685 | -0.039 | -0.4036 | No |
64 | RPS9 | RPS9 Entrez,  Source | ribosomal protein S9 | 8689 | -0.039 | -0.4012 | No |
65 | RPS17 | RPS17 Entrez,  Source | ribosomal protein S17 | 8724 | -0.039 | -0.4011 | No |
66 | RPS14 | RPS14 Entrez,  Source | ribosomal protein S14 | 8780 | -0.040 | -0.4025 | No |
67 | RPS23 | RPS23 Entrez,  Source | ribosomal protein S23 | 8803 | -0.041 | -0.4014 | No |
68 | RPS26 | RPS26 Entrez,  Source | ribosomal protein S26 | 8833 | -0.042 | -0.4008 | No |
69 | RPL7 | RPL7 Entrez,  Source | ribosomal protein L7 | 8850 | -0.042 | -0.3992 | No |
70 | RPL30 | RPL30 Entrez,  Source | ribosomal protein L30 | 8866 | -0.043 | -0.3975 | No |
71 | RPS21 | RPS21 Entrez,  Source | ribosomal protein S21 | 8897 | -0.044 | -0.3968 | No |
72 | DES | DES Entrez,  Source | desmin | 8928 | -0.044 | -0.3961 | No |
73 | RPS8 | RPS8 Entrez,  Source | ribosomal protein S8 | 8933 | -0.044 | -0.3934 | No |
74 | RPL27 | RPL27 Entrez,  Source | ribosomal protein L27 | 9053 | -0.047 | -0.3992 | No |
75 | RPL19 | RPL19 Entrez,  Source | ribosomal protein L19 | 9063 | -0.048 | -0.3967 | No |
76 | HIP1 | HIP1 Entrez,  Source | huntingtin interacting protein 1 | 9098 | -0.049 | -0.3960 | No |
77 | GFAP | GFAP Entrez,  Source | glial fibrillary acidic protein | 9126 | -0.049 | -0.3947 | No |
78 | RPL13 | RPL13 Entrez,  Source | ribosomal protein L13 | 9201 | -0.051 | -0.3968 | No |
79 | RPS4X | RPS4X Entrez,  Source | ribosomal protein S4, X-linked | 9239 | -0.052 | -0.3961 | No |
80 | RPL6 | RPL6 Entrez,  Source | ribosomal protein L6 | 9278 | -0.054 | -0.3953 | No |
81 | RPS16 | RPS16 Entrez,  Source | ribosomal protein S16 | 9287 | -0.054 | -0.3923 | No |
82 | RPL15 | RPL15 Entrez,  Source | ribosomal protein L15 | 9322 | -0.055 | -0.3912 | No |
83 | RPS2 | RPS2 Entrez,  Source | ribosomal protein S2 | 9340 | -0.055 | -0.3887 | No |
84 | RPS15A | RPS15A Entrez,  Source | ribosomal protein S15a | 9391 | -0.057 | -0.3887 | No |
85 | RPS3 | RPS3 Entrez,  Source | ribosomal protein S3 | 9405 | -0.057 | -0.3858 | No |
86 | SEPT5 | SEPT5 Entrez,  Source | septin 5 | 9433 | -0.058 | -0.3839 | No |
87 | RPL14 | RPL14 Entrez,  Source | ribosomal protein L14 | 9445 | -0.058 | -0.3809 | No |
88 | ACTL7B | ACTL7B Entrez,  Source | actin-like 7B | 9475 | -0.059 | -0.3791 | No |
89 | RPL18 | RPL18 Entrez,  Source | ribosomal protein L18 | 9495 | -0.060 | -0.3765 | No |
90 | ARPC5 | ARPC5 Entrez,  Source | actin related protein 2/3 complex, subunit 5, 16kDa | 9496 | -0.060 | -0.3725 | No |
91 | RPL22 | RPL22 Entrez,  Source | ribosomal protein L22 | 9500 | -0.060 | -0.3687 | No |
92 | RPS10 | RPS10 Entrez,  Source | ribosomal protein S10 | 9591 | -0.062 | -0.3713 | No |
93 | SEPT4 | SEPT4 Entrez,  Source | septin 4 | 9616 | -0.063 | -0.3689 | No |
94 | RPS5 | RPS5 Entrez,  Source | ribosomal protein S5 | 9640 | -0.064 | -0.3663 | No |
95 | MGP | MGP Entrez,  Source | matrix Gla protein | 9643 | -0.064 | -0.3622 | No |
96 | RPS12 | RPS12 Entrez,  Source | ribosomal protein S12 | 9651 | -0.064 | -0.3584 | No |
97 | ACTC1 | ACTC1 Entrez,  Source | actin, alpha, cardiac muscle 1 | 9699 | -0.065 | -0.3575 | No |
98 | RPS15 | RPS15 Entrez,  Source | ribosomal protein S15 | 9780 | -0.067 | -0.3591 | No |
99 | TUBG1 | TUBG1 Entrez,  Source | tubulin, gamma 1 | 9827 | -0.069 | -0.3579 | No |
100 | RPS11 | RPS11 Entrez,  Source | ribosomal protein S11 | 9846 | -0.070 | -0.3546 | No |
101 | RPL11 | RPL11 Entrez,  Source | ribosomal protein L11 | 10109 | -0.079 | -0.3691 | No |
102 | ADD3 | ADD3 Entrez,  Source | adducin 3 (gamma) | 10162 | -0.080 | -0.3676 | No |
103 | SPAG4 | SPAG4 Entrez,  Source | sperm associated antigen 4 | 10309 | -0.085 | -0.3730 | No |
104 | ARPC1B | ARPC1B Entrez,  Source | actin related protein 2/3 complex, subunit 1B, 41kDa | 10374 | -0.087 | -0.3719 | No |
105 | FBLN2 | FBLN2 Entrez,  Source | fibulin 2 | 10393 | -0.088 | -0.3673 | No |
106 | ACTB | ACTB Entrez,  Source | actin, beta | 10590 | -0.095 | -0.3758 | No |
107 | PLEC1 | PLEC1 Entrez,  Source | plectin 1, intermediate filament binding protein 500kDa | 10694 | -0.098 | -0.3770 | No |
108 | RPS19 | RPS19 Entrez,  Source | ribosomal protein S19 | 10892 | -0.106 | -0.3847 | No |
109 | RPL13A | RPL13A Entrez,  Source | ribosomal protein L13a | 10925 | -0.108 | -0.3799 | No |
110 | LMNB1 | LMNB1 Entrez,  Source | lamin B1 | 11329 | -0.128 | -0.4018 | No |
111 | SMTN | SMTN Entrez,  Source | smoothelin | 11525 | -0.139 | -0.4072 | No |
112 | ODF2 | ODF2 Entrez,  Source | outer dense fiber of sperm tails 2 | 11533 | -0.139 | -0.3983 | No |
113 | SEPT7 | SEPT7 Entrez,  Source | septin 7 | 11577 | -0.142 | -0.3920 | No |
114 | MATR3 | MATR3 Entrez,  Source | matrin 3 | 11605 | -0.144 | -0.3844 | No |
115 | SORBS2 | SORBS2 Entrez,  Source | sorbin and SH3 domain containing 2 | 12297 | -0.204 | -0.4229 | No |
116 | NUMA1 | NUMA1 Entrez,  Source | nuclear mitotic apparatus protein 1 | 12531 | -0.233 | -0.4248 | Yes |
117 | TPM4 | TPM4 Entrez,  Source | tropomyosin 4 | 12551 | -0.235 | -0.4104 | Yes |
118 | DSP | DSP Entrez,  Source | desmoplakin | 12592 | -0.244 | -0.3970 | Yes |
119 | LAMC1 | LAMC1 Entrez,  Source | laminin, gamma 1 (formerly LAMB2) | 12835 | -0.298 | -0.3953 | Yes |
120 | MPZL1 | MPZL1 Entrez,  Source | myelin protein zero-like 1 | 12872 | -0.311 | -0.3771 | Yes |
121 | TPM1 | TPM1 Entrez,  Source | tropomyosin 1 (alpha) | 12998 | -0.364 | -0.3620 | Yes |
122 | VIM | VIM Entrez,  Source | vimentin | 13164 | -0.501 | -0.3408 | Yes |
123 | EFEMP2 | EFEMP2 Entrez,  Source | EGF-containing fibulin-like extracellular matrix protein 2 | 13229 | -0.627 | -0.3034 | Yes |
124 | MSN | MSN Entrez,  Source | moesin | 13302 | -0.941 | -0.2455 | Yes |
125 | NEFL | NEFL Entrez,  Source | neurofilament, light polypeptide 68kDa | 13304 | -0.959 | -0.1809 | Yes |
126 | ANXA1 | ANXA1 Entrez,  Source | annexin A1 | 13327 | -1.146 | -0.1054 | Yes |
127 | ACTA1 | ACTA1 Entrez,  Source | actin, alpha 1, skeletal muscle | 13340 | -1.581 | 0.0002 | Yes |