Datasetdouble_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls
#double_gel_8d_versus_single_gel_8d.class.cls
#double_gel_8d_versus_single_gel_8d_repos
Phenotypeclass.cls#double_gel_8d_versus_single_gel_8d_repos
Upregulated in classsingle_gel_8d
GeneSetSTRUCTURAL_MOLECULE_ACTIVITY
Enrichment Score (ES)-0.44052064
Normalized Enrichment Score (NES)-1.6322314
Nominal p-value0.0017889087
FDR q-value0.10332504
FWER p-Value1.0
Table: GSEA Results Summary



Fig 1: Enrichment plot: STRUCTURAL_MOLECULE_ACTIVITY   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

PROBEGENE SYMBOLGENE_TITLERANK IN GENE LISTRANK METRIC SCORERUNNING ESCORE ENRICHMENT
1CORO1ACORO1A
Entrez,  Source
coronin, actin binding protein, 1A1360.5560.0272No
2ANK1ANK1
Entrez,  Source
ankyrin 1, erythrocytic5250.2920.0175No
3MYBPHMYBPH
Entrez,  Source
myosin binding protein H9190.2040.0015No
4MALMAL
Entrez,  Source
mal, T-cell differentiation protein15720.144-0.0381No
5SPTBN4SPTBN4
Entrez,  Source
spectrin, beta, non-erythrocytic 416510.140-0.0346No
6MATN1MATN1
Entrez,  Source
matrilin 1, cartilage matrix protein17020.137-0.0292No
7MYL3MYL3
Entrez,  Source
myosin, light chain 3, alkali; ventricular, skeletal, slow18440.129-0.0311No
8MRPL12MRPL12
Entrez,  Source
mitochondrial ribosomal protein L1219400.124-0.0300No
9DMDDMD
Entrez,  Source
dystrophin (muscular dystrophy, Duchenne and Becker types)21460.116-0.0376No
10FBN2FBN2
Entrez,  Source
fibrillin 2 (congenital contractural arachnodactyly)24080.106-0.0502No
11DSPPDSPP
Entrez,  Source
dentin sialophosphoprotein24180.106-0.0438No
12BFARBFAR
Entrez,  Source
bifunctional apoptosis regulator32410.077-0.1008No
13MRPL41MRPL41
Entrez,  Source
mitochondrial ribosomal protein L4133470.075-0.1037No
14MYH6MYH6
Entrez,  Source
myosin, heavy chain 6, cardiac muscle, alpha (cardiomyopathy, hypertrophic 1)36030.069-0.1183No
15MAPK8IP2MAPK8IP2
Entrez,  Source
mitogen-activated protein kinase 8 interacting protein 236380.068-0.1163No
16MRPS7MRPS7
Entrez,  Source
mitochondrial ribosomal protein S737450.065-0.1200No
17IMPG1IMPG1
Entrez,  Source
interphotoreceptor matrix proteoglycan 137960.064-0.1194No
18FBN1FBN1
Entrez,  Source
fibrillin 141220.057-0.1402No
19MEPEMEPE
Entrez,  Source
matrix, extracellular phosphoglycoprotein with ASARM motif (bone)43220.052-0.1517No
20TTNTTN
Entrez,  Source
titin44010.050-0.1543No
21RPL21RPL21
Entrez,  Source
ribosomal protein L2147900.042-0.1808No
22MAPTMAPT
Entrez,  Source
microtubule-associated protein tau48120.042-0.1796No
23CHI3L1CHI3L1
Entrez,  Source
chitinase 3-like 1 (cartilage glycoprotein-39)49370.039-0.1863No
24ACTN3ACTN3
Entrez,  Source
actinin, alpha 351590.035-0.2007No
25MYH11MYH11
Entrez,  Source
myosin, heavy chain 11, smooth muscle53150.032-0.2103No
26TFPI2TFPI2
Entrez,  Source
tissue factor pathway inhibitor 253170.032-0.2082No
27COMPCOMP
Entrez,  Source
cartilage oligomeric matrix protein53280.031-0.2069No
28IMPG2IMPG2
Entrez,  Source
interphotoreceptor matrix proteoglycan 255720.026-0.2235No
29MYOCMYOC
Entrez,  Source
myocilin, trabecular meshwork inducible glucocorticoid response60670.017-0.2597No
30MYL2MYL2
Entrez,  Source
myosin, light chain 2, regulatory, cardiac, slow62930.012-0.2759No
31MYBPC1MYBPC1
Entrez,  Source
myosin binding protein C, slow type7017-0.002-0.3305No
32RPL41RPL41
Entrez,  Source
ribosomal protein L417088-0.004-0.3355No
33RPL35RPL35
Entrez,  Source
ribosomal protein L357279-0.008-0.3494No
34COL4A4COL4A4
Entrez,  Source
collagen, type IV, alpha 47382-0.010-0.3564No
35RPS29RPS29
Entrez,  Source
ribosomal protein S297396-0.010-0.3567No
36RPL26RPL26
Entrez,  Source
ribosomal protein L267410-0.010-0.3570No
37RPL37RPL37
Entrez,  Source
ribosomal protein L377466-0.012-0.3604No
38RPL39RPL39
Entrez,  Source
ribosomal protein L397472-0.012-0.3600No
39RPS18RPS18
Entrez,  Source
ribosomal protein S187553-0.014-0.3651No
40MRPL23MRPL23
Entrez,  Source
mitochondrial ribosomal protein L237650-0.016-0.3713No
41PRELPPRELP
Entrez,  Source
proline/arginine-rich end leucine-rich repeat protein7654-0.016-0.3705No
42IVLIVL
Entrez,  Source
involucrin7745-0.018-0.3761No
43RPS6RPS6
Entrez,  Source
ribosomal protein S67800-0.019-0.3790No
44MYH7MYH7
Entrez,  Source
myosin, heavy chain 7, cardiac muscle, beta7898-0.021-0.3849No
45RPS25RPS25
Entrez,  Source
ribosomal protein S258011-0.024-0.3918No
46BFSP1BFSP1
Entrez,  Source
beaded filament structural protein 1, filensin8014-0.024-0.3903No
47RPS20RPS20
Entrez,  Source
ribosomal protein S208019-0.024-0.3890No
48RPLP1RPLP1
Entrez,  Source
ribosomal protein, large, P18028-0.024-0.3880No
49RPL3RPL3
Entrez,  Source
ribosomal protein L38109-0.026-0.3923No
50RPL4RPL4
Entrez,  Source
ribosomal protein L48146-0.026-0.3933No
51RPL31RPL31
Entrez,  Source
ribosomal protein L318192-0.027-0.3948No
52RPL8RPL8
Entrez,  Source
ribosomal protein L88255-0.029-0.3976No
53RPS24RPS24
Entrez,  Source
ribosomal protein S248294-0.030-0.3985No
54RPL9RPL9
Entrez,  Source
ribosomal protein L98332-0.031-0.3992No
55RPL24RPL24
Entrez,  Source
ribosomal protein L248338-0.031-0.3975No
56RPS27RPS27
Entrez,  Source
ribosomal protein S27 (metallopanstimulin 1)8382-0.032-0.3986No
57RPS3ARPS3A
Entrez,  Source
ribosomal protein S3A8514-0.035-0.4062No
58RPL5RPL5
Entrez,  Source
ribosomal protein L58527-0.035-0.4047No
59RPS13RPS13
Entrez,  Source
ribosomal protein S138611-0.037-0.4085No
60RPL28RPL28
Entrez,  Source
ribosomal protein L288612-0.037-0.4060No
61SORBS3SORBS3
Entrez,  Source
sorbin and SH3 domain containing 38634-0.037-0.4050No
62RPL29RPL29
Entrez,  Source
ribosomal protein L298680-0.039-0.4059No
63MYOM1MYOM1
Entrez,  Source
myomesin 1 (skelemin) 185kDa8685-0.039-0.4036No
64RPS9RPS9
Entrez,  Source
ribosomal protein S98689-0.039-0.4012No
65RPS17RPS17
Entrez,  Source
ribosomal protein S178724-0.039-0.4011No
66RPS14RPS14
Entrez,  Source
ribosomal protein S148780-0.040-0.4025No
67RPS23RPS23
Entrez,  Source
ribosomal protein S238803-0.041-0.4014No
68RPS26RPS26
Entrez,  Source
ribosomal protein S268833-0.042-0.4008No
69RPL7RPL7
Entrez,  Source
ribosomal protein L78850-0.042-0.3992No
70RPL30RPL30
Entrez,  Source
ribosomal protein L308866-0.043-0.3975No
71RPS21RPS21
Entrez,  Source
ribosomal protein S218897-0.044-0.3968No
72DESDES
Entrez,  Source
desmin8928-0.044-0.3961No
73RPS8RPS8
Entrez,  Source
ribosomal protein S88933-0.044-0.3934No
74RPL27RPL27
Entrez,  Source
ribosomal protein L279053-0.047-0.3992No
75RPL19RPL19
Entrez,  Source
ribosomal protein L199063-0.048-0.3967No
76HIP1HIP1
Entrez,  Source
huntingtin interacting protein 19098-0.049-0.3960No
77GFAPGFAP
Entrez,  Source
glial fibrillary acidic protein9126-0.049-0.3947No
78RPL13RPL13
Entrez,  Source
ribosomal protein L139201-0.051-0.3968No
79RPS4XRPS4X
Entrez,  Source
ribosomal protein S4, X-linked9239-0.052-0.3961No
80RPL6RPL6
Entrez,  Source
ribosomal protein L69278-0.054-0.3953No
81RPS16RPS16
Entrez,  Source
ribosomal protein S169287-0.054-0.3923No
82RPL15RPL15
Entrez,  Source
ribosomal protein L159322-0.055-0.3912No
83RPS2RPS2
Entrez,  Source
ribosomal protein S29340-0.055-0.3887No
84RPS15ARPS15A
Entrez,  Source
ribosomal protein S15a9391-0.057-0.3887No
85RPS3RPS3
Entrez,  Source
ribosomal protein S39405-0.057-0.3858No
86SEPT5SEPT5
Entrez,  Source
septin 59433-0.058-0.3839No
87RPL14RPL14
Entrez,  Source
ribosomal protein L149445-0.058-0.3809No
88ACTL7BACTL7B
Entrez,  Source
actin-like 7B9475-0.059-0.3791No
89RPL18RPL18
Entrez,  Source
ribosomal protein L189495-0.060-0.3765No
90ARPC5ARPC5
Entrez,  Source
actin related protein 2/3 complex, subunit 5, 16kDa9496-0.060-0.3725No
91RPL22RPL22
Entrez,  Source
ribosomal protein L229500-0.060-0.3687No
92RPS10RPS10
Entrez,  Source
ribosomal protein S109591-0.062-0.3713No
93SEPT4SEPT4
Entrez,  Source
septin 49616-0.063-0.3689No
94RPS5RPS5
Entrez,  Source
ribosomal protein S59640-0.064-0.3663No
95MGPMGP
Entrez,  Source
matrix Gla protein9643-0.064-0.3622No
96RPS12RPS12
Entrez,  Source
ribosomal protein S129651-0.064-0.3584No
97ACTC1ACTC1
Entrez,  Source
actin, alpha, cardiac muscle 19699-0.065-0.3575No
98RPS15RPS15
Entrez,  Source
ribosomal protein S159780-0.067-0.3591No
99TUBG1TUBG1
Entrez,  Source
tubulin, gamma 19827-0.069-0.3579No
100RPS11RPS11
Entrez,  Source
ribosomal protein S119846-0.070-0.3546No
101RPL11RPL11
Entrez,  Source
ribosomal protein L1110109-0.079-0.3691No
102ADD3ADD3
Entrez,  Source
adducin 3 (gamma)10162-0.080-0.3676No
103SPAG4SPAG4
Entrez,  Source
sperm associated antigen 410309-0.085-0.3730No
104ARPC1BARPC1B
Entrez,  Source
actin related protein 2/3 complex, subunit 1B, 41kDa10374-0.087-0.3719No
105FBLN2FBLN2
Entrez,  Source
fibulin 210393-0.088-0.3673No
106ACTBACTB
Entrez,  Source
actin, beta10590-0.095-0.3758No
107PLEC1PLEC1
Entrez,  Source
plectin 1, intermediate filament binding protein 500kDa10694-0.098-0.3770No
108RPS19RPS19
Entrez,  Source
ribosomal protein S1910892-0.106-0.3847No
109RPL13ARPL13A
Entrez,  Source
ribosomal protein L13a10925-0.108-0.3799No
110LMNB1LMNB1
Entrez,  Source
lamin B111329-0.128-0.4018No
111SMTNSMTN
Entrez,  Source
smoothelin11525-0.139-0.4072No
112ODF2ODF2
Entrez,  Source
outer dense fiber of sperm tails 211533-0.139-0.3983No
113SEPT7SEPT7
Entrez,  Source
septin 711577-0.142-0.3920No
114MATR3MATR3
Entrez,  Source
matrin 311605-0.144-0.3844No
115SORBS2SORBS2
Entrez,  Source
sorbin and SH3 domain containing 212297-0.204-0.4229No
116NUMA1NUMA1
Entrez,  Source
nuclear mitotic apparatus protein 112531-0.233-0.4248Yes
117TPM4TPM4
Entrez,  Source
tropomyosin 412551-0.235-0.4104Yes
118DSPDSP
Entrez,  Source
desmoplakin12592-0.244-0.3970Yes
119LAMC1LAMC1
Entrez,  Source
laminin, gamma 1 (formerly LAMB2)12835-0.298-0.3953Yes
120MPZL1MPZL1
Entrez,  Source
myelin protein zero-like 112872-0.311-0.3771Yes
121TPM1TPM1
Entrez,  Source
tropomyosin 1 (alpha)12998-0.364-0.3620Yes
122VIMVIM
Entrez,  Source
vimentin13164-0.501-0.3408Yes
123EFEMP2EFEMP2
Entrez,  Source
EGF-containing fibulin-like extracellular matrix protein 213229-0.627-0.3034Yes
124MSNMSN
Entrez,  Source
moesin13302-0.941-0.2455Yes
125NEFLNEFL
Entrez,  Source
neurofilament, light polypeptide 68kDa13304-0.959-0.1809Yes
126ANXA1ANXA1
Entrez,  Source
annexin A113327-1.146-0.1054Yes
127ACTA1ACTA1
Entrez,  Source
actin, alpha 1, skeletal muscle13340-1.5810.0002Yes
Table: GSEA details [plain text format]



Fig 2: STRUCTURAL_MOLECULE_ACTIVITY   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet



Fig 3: STRUCTURAL_MOLECULE_ACTIVITY: Random ES distribution   
Gene set null distribution of ES for STRUCTURAL_MOLECULE_ACTIVITY