Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_single_gel_8d.class.cls #double_gel_8d_versus_single_gel_8d_repos |
| Phenotype | class.cls#double_gel_8d_versus_single_gel_8d_repos |
| Upregulated in class | single_gel_8d |
| GeneSet | TAKEDA_NUP8_HOXA9_3D_UP |
| Enrichment Score (ES) | -0.50755084 |
| Normalized Enrichment Score (NES) | -1.7421205 |
| Nominal p-value | 0.0056074765 |
| FDR q-value | 0.06524712 |
| FWER p-Value | 0.996 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | VNN1 | VNN1 Entrez, Source | vanin 1 | 249 | 0.436 | 0.0182 | No |
| 2 | IGFBP4 | IGFBP4 Entrez, Source | insulin-like growth factor binding protein 4 | 456 | 0.317 | 0.0296 | No |
| 3 | SLC5A3 | SLC5A3 Entrez, Source | solute carrier family 5 (inositol transporters), member 3 | 565 | 0.279 | 0.0452 | No |
| 4 | IFIT2 | IFIT2 Entrez, Source | interferon-induced protein with tetratricopeptide repeats 2 | 609 | 0.264 | 0.0643 | No |
| 5 | PLSCR1 | PLSCR1 Entrez, Source | phospholipid scramblase 1 | 1228 | 0.168 | 0.0320 | No |
| 6 | HERC6 | HERC6 Entrez, Source | hect domain and RLD 6 | 1285 | 0.165 | 0.0418 | No |
| 7 | FGF18 | FGF18 Entrez, Source | fibroblast growth factor 18 | 1301 | 0.164 | 0.0546 | No |
| 8 | CYP1A1 | CYP1A1 Entrez, Source | cytochrome P450, family 1, subfamily A, polypeptide 1 | 1331 | 0.162 | 0.0662 | No |
| 9 | IFIT3 | IFIT3 Entrez, Source | interferon-induced protein with tetratricopeptide repeats 3 | 1407 | 0.156 | 0.0738 | No |
| 10 | ACSL4 | ACSL4 Entrez, Source | acyl-CoA synthetase long-chain family member 4 | 1566 | 0.144 | 0.0742 | No |
| 11 | BST2 | BST2 Entrez, Source | bone marrow stromal cell antigen 2 | 1811 | 0.130 | 0.0668 | No |
| 12 | ANGPT1 | ANGPT1 Entrez, Source | angiopoietin 1 | 2387 | 0.107 | 0.0326 | No |
| 13 | GUCY1A3 | GUCY1A3 Entrez, Source | guanylate cyclase 1, soluble, alpha 3 | 3179 | 0.079 | -0.0203 | No |
| 14 | ERG | ERG Entrez, Source | v-ets erythroblastosis virus E26 oncogene homolog (avian) | 3255 | 0.077 | -0.0194 | No |
| 15 | SERPING1 | SERPING1 Entrez, Source | serpin peptidase inhibitor, clade G (C1 inhibitor), member 1, (angioedema, hereditary) | 3378 | 0.074 | -0.0223 | No |
| 16 | IGJ | IGJ Entrez, Source | immunoglobulin J polypeptide, linker protein for immunoglobulin alpha and mu polypeptides | 3441 | 0.073 | -0.0208 | No |
| 17 | QPRT | QPRT Entrez, Source | quinolinate phosphoribosyltransferase (nicotinate-nucleotide pyrophosphorylase (carboxylating)) | 3739 | 0.065 | -0.0376 | No |
| 18 | TRIM9 | TRIM9 Entrez, Source | tripartite motif-containing 9 | 3829 | 0.063 | -0.0390 | No |
| 19 | CRHBP | CRHBP Entrez, Source | corticotropin releasing hormone binding protein | 4478 | 0.049 | -0.0837 | No |
| 20 | OAS1 | OAS1 Entrez, Source | 2',5'-oligoadenylate synthetase 1, 40/46kDa | 4549 | 0.047 | -0.0849 | No |
| 21 | ACSM3 | ACSM3 Entrez, Source | acyl-CoA synthetase medium-chain family member 3 | 4786 | 0.042 | -0.0991 | No |
| 22 | STAT1 | STAT1 Entrez, Source | signal transducer and activator of transcription 1, 91kDa | 4819 | 0.041 | -0.0980 | No |
| 23 | RNASE6 | RNASE6 Entrez, Source | ribonuclease, RNase A family, k6 | 4848 | 0.041 | -0.0966 | No |
| 24 | IFIT1 | IFIT1 Entrez, Source | interferon-induced protein with tetratricopeptide repeats 1 | 4940 | 0.039 | -0.1002 | No |
| 25 | ANGPT2 | ANGPT2 Entrez, Source | angiopoietin 2 | 5033 | 0.037 | -0.1039 | No |
| 26 | CXCL10 | CXCL10 Entrez, Source | chemokine (C-X-C motif) ligand 10 | 5128 | 0.035 | -0.1080 | No |
| 27 | CH25H | CH25H Entrez, Source | cholesterol 25-hydroxylase | 5364 | 0.031 | -0.1231 | No |
| 28 | PTGER3 | PTGER3 Entrez, Source | prostaglandin E receptor 3 (subtype EP3) | 5626 | 0.025 | -0.1407 | No |
| 29 | STAT2 | STAT2 Entrez, Source | signal transducer and activator of transcription 2, 113kDa | 5795 | 0.022 | -0.1514 | No |
| 30 | PTGS1 | PTGS1 Entrez, Source | prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase) | 6103 | 0.016 | -0.1732 | No |
| 31 | SLC12A8 | SLC12A8 Entrez, Source | solute carrier family 12 (potassium/chloride transporters), member 8 | 6267 | 0.013 | -0.1844 | No |
| 32 | FOXP1 | FOXP1 Entrez, Source | forkhead box P1 | 6378 | 0.010 | -0.1919 | No |
| 33 | MX1 | MX1 Entrez, Source | myxovirus (influenza virus) resistance 1, interferon-inducible protein p78 (mouse) | 6404 | 0.009 | -0.1929 | No |
| 34 | CLSTN3 | CLSTN3 Entrez, Source | calsyntenin 3 | 6678 | 0.005 | -0.2131 | No |
| 35 | NEGR1 | NEGR1 Entrez, Source | neuronal growth regulator 1 | 7019 | -0.003 | -0.2385 | No |
| 36 | MVP | MVP Entrez, Source | major vault protein | 7452 | -0.011 | -0.2701 | No |
| 37 | PDE1C | PDE1C Entrez, Source | phosphodiesterase 1C, calmodulin-dependent 70kDa | 7826 | -0.019 | -0.2966 | No |
| 38 | BMP2K | BMP2K Entrez, Source | BMP2 inducible kinase | 7875 | -0.020 | -0.2985 | No |
| 39 | INDO | INDO Entrez, Source | indoleamine-pyrrole 2,3 dioxygenase | 8124 | -0.026 | -0.3150 | No |
| 40 | HEY1 | HEY1 Entrez, Source | hairy/enhancer-of-split related with YRPW motif 1 | 9090 | -0.048 | -0.3836 | No |
| 41 | IRF7 | IRF7 Entrez, Source | interferon regulatory factor 7 | 9191 | -0.051 | -0.3868 | No |
| 42 | CUGBP2 | CUGBP2 Entrez, Source | CUG triplet repeat, RNA binding protein 2 | 9236 | -0.052 | -0.3857 | No |
| 43 | MX2 | MX2 Entrez, Source | myxovirus (influenza virus) resistance 2 (mouse) | 9835 | -0.069 | -0.4249 | No |
| 44 | MLLT3 | MLLT3 Entrez, Source | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3 | 9964 | -0.074 | -0.4283 | No |
| 45 | RAD50 | RAD50 Entrez, Source | RAD50 homolog (S. cerevisiae) | 10151 | -0.080 | -0.4355 | No |
| 46 | HOXA5 | HOXA5 Entrez, Source | homeobox A5 | 10345 | -0.086 | -0.4427 | No |
| 47 | OLFM3 | OLFM3 Entrez, Source | olfactomedin 3 | 10384 | -0.088 | -0.4382 | No |
| 48 | PTGS2 | PTGS2 Entrez, Source | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | 10604 | -0.095 | -0.4466 | No |
| 49 | CRISP2 | CRISP2 Entrez, Source | cysteine-rich secretory protein 2 | 10913 | -0.108 | -0.4607 | No |
| 50 | SP110 | SP110 Entrez, Source | SP110 nuclear body protein | 11080 | -0.116 | -0.4634 | No |
| 51 | EIF2AK2 | EIF2AK2 Entrez, Source | eukaryotic translation initiation factor 2-alpha kinase 2 | 11121 | -0.118 | -0.4564 | No |
| 52 | TXK | TXK Entrez, Source | TXK tyrosine kinase | 11150 | -0.119 | -0.4484 | No |
| 53 | AHR | AHR Entrez, Source | aryl hydrocarbon receptor | 11529 | -0.139 | -0.4650 | No |
| 54 | ATP1B1 | ATP1B1 Entrez, Source | ATPase, Na+/K+ transporting, beta 1 polypeptide | 11599 | -0.144 | -0.4581 | No |
| 55 | KLF5 | KLF5 Entrez, Source | Kruppel-like factor 5 (intestinal) | 11774 | -0.155 | -0.4580 | No |
| 56 | S100A10 | S100A10 Entrez, Source | S100 calcium binding protein A10 | 12432 | -0.219 | -0.4890 | Yes |
| 57 | RERE | RERE Entrez, Source | arginine-glutamic acid dipeptide (RE) repeats | 12466 | -0.223 | -0.4725 | Yes |
| 58 | PTPRD | PTPRD Entrez, Source | protein tyrosine phosphatase, receptor type, D | 12478 | -0.224 | -0.4543 | Yes |
| 59 | USP18 | USP18 Entrez, Source | ubiquitin specific peptidase 18 | 12554 | -0.237 | -0.4399 | Yes |
| 60 | CDKN1C | CDKN1C Entrez, Source | cyclin-dependent kinase inhibitor 1C (p57, Kip2) | 12725 | -0.270 | -0.4298 | Yes |
| 61 | ST6GALNAC1 | ST6GALNAC1 Entrez, Source | ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 1 | 12757 | -0.277 | -0.4087 | Yes |
| 62 | BAMBI | BAMBI Entrez, Source | BMP and activin membrane-bound inhibitor homolog (Xenopus laevis) | 12826 | -0.295 | -0.3888 | Yes |
| 63 | IFI44 | IFI44 Entrez, Source | interferon-induced protein 44 | 12827 | -0.295 | -0.3638 | Yes |
| 64 | IFI35 | IFI35 Entrez, Source | interferon-induced protein 35 | 12894 | -0.318 | -0.3418 | Yes |
| 65 | PLA2G4A | PLA2G4A Entrez, Source | phospholipase A2, group IVA (cytosolic, calcium-dependent) | 12946 | -0.338 | -0.3170 | Yes |
| 66 | GMPR | GMPR Entrez, Source | guanosine monophosphate reductase | 12951 | -0.339 | -0.2885 | Yes |
| 67 | ALDH1A1 | ALDH1A1 Entrez, Source | aldehyde dehydrogenase 1 family, member A1 | 12985 | -0.357 | -0.2607 | Yes |
| 68 | LGALS3BP | LGALS3BP Entrez, Source | lectin, galactoside-binding, soluble, 3 binding protein | 13114 | -0.440 | -0.2330 | Yes |
| 69 | PRSS23 | PRSS23 Entrez, Source | protease, serine, 23 | 13122 | -0.445 | -0.1958 | Yes |
| 70 | CD69 | CD69 Entrez, Source | CD69 molecule | 13130 | -0.450 | -0.1582 | Yes |
| 71 | RTN1 | RTN1 Entrez, Source | reticulon 1 | 13181 | -0.527 | -0.1172 | Yes |
| 72 | BDNF | BDNF Entrez, Source | brain-derived neurotrophic factor | 13183 | -0.530 | -0.0722 | Yes |
| 73 | LOX | LOX Entrez, Source | lysyl oxidase | 13308 | -0.991 | 0.0026 | Yes |
