Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_single_gel_8d.class.cls #double_gel_8d_versus_single_gel_8d_repos |
| Phenotype | class.cls#double_gel_8d_versus_single_gel_8d_repos |
| Upregulated in class | single_gel_8d |
| GeneSet | TGFBETA_EARLY_UP |
| Enrichment Score (ES) | -0.6294166 |
| Normalized Enrichment Score (NES) | -1.9066409 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.021125922 |
| FWER p-Value | 0.435 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | IGFBP2 | IGFBP2 Entrez, Source | insulin-like growth factor binding protein 2, 36kDa | 378 | 0.352 | 0.0244 | No |
| 2 | SERPINE1 | SERPINE1 Entrez, Source | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 1938 | 0.125 | -0.0740 | No |
| 3 | IGFBP5 | IGFBP5 Entrez, Source | insulin-like growth factor binding protein 5 | 2222 | 0.114 | -0.0783 | No |
| 4 | MMP3 | MMP3 Entrez, Source | matrix metallopeptidase 3 (stromelysin 1, progelatinase) | 2981 | 0.085 | -0.1224 | No |
| 5 | WNT2B | WNT2B Entrez, Source | wingless-type MMTV integration site family, member 2B | 3037 | 0.084 | -0.1139 | No |
| 6 | RHOG | RHOG Entrez, Source | ras homolog gene family, member G (rho G) | 3472 | 0.072 | -0.1358 | No |
| 7 | RHOB | RHOB Entrez, Source | ras homolog gene family, member B | 3872 | 0.063 | -0.1563 | No |
| 8 | ITGB5 | ITGB5 Entrez, Source | integrin, beta 5 | 3998 | 0.059 | -0.1568 | No |
| 9 | DVL1 | DVL1 Entrez, Source | dishevelled, dsh homolog 1 (Drosophila) | 4410 | 0.050 | -0.1802 | No |
| 10 | LRRC17 | LRRC17 Entrez, Source | leucine rich repeat containing 17 | 5108 | 0.036 | -0.2272 | No |
| 11 | IGFBP3 | IGFBP3 Entrez, Source | insulin-like growth factor binding protein 3 | 6247 | 0.013 | -0.3108 | No |
| 12 | ITGB2 | ITGB2 Entrez, Source | integrin, beta 2 (complement component 3 receptor 3 and 4 subunit) | 6482 | 0.008 | -0.3271 | No |
| 13 | NID1 | NID1 Entrez, Source | nidogen 1 | 6775 | 0.003 | -0.3487 | No |
| 14 | BSG | BSG Entrez, Source | basigin (Ok blood group) | 6969 | -0.001 | -0.3630 | No |
| 15 | RND3 | RND3 Entrez, Source | Rho family GTPase 3 | 7115 | -0.004 | -0.3732 | No |
| 16 | ICAM1 | ICAM1 Entrez, Source | intercellular adhesion molecule 1 (CD54), human rhinovirus receptor | 7160 | -0.005 | -0.3757 | No |
| 17 | PAK1 | PAK1 Entrez, Source | p21/Cdc42/Rac1-activated kinase 1 (STE20 homolog, yeast) | 7664 | -0.016 | -0.4112 | No |
| 18 | LRP1 | LRP1 Entrez, Source | low density lipoprotein-related protein 1 (alpha-2-macroglobulin receptor) | 8598 | -0.037 | -0.4758 | No |
| 19 | CDH6 | CDH6 Entrez, Source | cadherin 6, type 2, K-cadherin (fetal kidney) | 8608 | -0.037 | -0.4709 | No |
| 20 | FN1 | FN1 Entrez, Source | fibronectin 1 | 9917 | -0.072 | -0.5584 | No |
| 21 | ARHGDIA | ARHGDIA Entrez, Source | Rho GDP dissociation inhibitor (GDI) alpha | 9931 | -0.073 | -0.5484 | No |
| 22 | SPARC | SPARC Entrez, Source | secreted protein, acidic, cysteine-rich (osteonectin) | 10444 | -0.090 | -0.5734 | No |
| 23 | RHOA | RHOA Entrez, Source | ras homolog gene family, member A | 11190 | -0.121 | -0.6113 | Yes |
| 24 | IGF2R | IGF2R Entrez, Source | insulin-like growth factor 2 receptor | 11315 | -0.127 | -0.6015 | Yes |
| 25 | CSPG2 | CSPG2 Entrez, Source | chondroitin sulfate proteoglycan 2 (versican) | 11420 | -0.132 | -0.5895 | Yes |
| 26 | CD59 | CD59 Entrez, Source | CD59 molecule, complement regulatory protein | 11683 | -0.149 | -0.5868 | Yes |
| 27 | PXN | PXN Entrez, Source | paxillin | 11831 | -0.159 | -0.5740 | Yes |
| 28 | MMP14 | MMP14 Entrez, Source | matrix metallopeptidase 14 (membrane-inserted) | 12177 | -0.189 | -0.5715 | Yes |
| 29 | JUP | JUP Entrez, Source | junction plakoglobin | 12351 | -0.210 | -0.5530 | Yes |
| 30 | ZYX | ZYX Entrez, Source | zyxin | 12724 | -0.270 | -0.5404 | Yes |
| 31 | NOTCH2 | NOTCH2 Entrez, Source | Notch homolog 2 (Drosophila) | 12734 | -0.272 | -0.5002 | Yes |
| 32 | COL1A2 | COL1A2 Entrez, Source | collagen, type I, alpha 2 | 12818 | -0.293 | -0.4624 | Yes |
| 33 | COL3A1 | COL3A1 Entrez, Source | collagen, type III, alpha 1 (Ehlers-Danlos syndrome type IV, autosomal dominant) | 12902 | -0.323 | -0.4201 | Yes |
| 34 | PLAT | PLAT Entrez, Source | plasminogen activator, tissue | 13010 | -0.371 | -0.3725 | Yes |
| 35 | RHOQ | RHOQ Entrez, Source | ras homolog gene family, member Q | 13078 | -0.412 | -0.3156 | Yes |
| 36 | TIMP1 | TIMP1 Entrez, Source | TIMP metallopeptidase inhibitor 1 | 13213 | -0.582 | -0.2384 | Yes |
| 37 | CD44 | CD44 Entrez, Source | CD44 molecule (Indian blood group) | 13233 | -0.633 | -0.1448 | Yes |
| 38 | MARCKSL1 | MARCKSL1 Entrez, Source | MARCKS-like 1 | 13312 | -1.018 | 0.0023 | Yes |
