Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_single_gel_8d.class.cls #double_gel_8d_versus_single_gel_8d_repos |
| Phenotype | class.cls#double_gel_8d_versus_single_gel_8d_repos |
| Upregulated in class | double_gel_8d |
| GeneSet | TNFALPHA_ADIP_DN |
| Enrichment Score (ES) | 0.58125347 |
| Normalized Enrichment Score (NES) | 1.8330953 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.010197295 |
| FWER p-Value | 0.779 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | G0S2 | G0S2 Entrez, Source | G0/G1switch 2 | 6 | 1.218 | 0.1195 | Yes |
| 2 | PEX11A | PEX11A Entrez, Source | peroxisomal biogenesis factor 11A | 65 | 0.704 | 0.1843 | Yes |
| 3 | PC | PC Entrez, Source | pyruvate carboxylase | 79 | 0.652 | 0.2476 | Yes |
| 4 | PFKFB1 | PFKFB1 Entrez, Source | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 | 95 | 0.621 | 0.3076 | Yes |
| 5 | FASN | FASN Entrez, Source | fatty acid synthase | 213 | 0.460 | 0.3440 | Yes |
| 6 | ACSL1 | ACSL1 Entrez, Source | acyl-CoA synthetase long-chain family member 1 | 335 | 0.375 | 0.3718 | Yes |
| 7 | BCKDHA | BCKDHA Entrez, Source | branched chain keto acid dehydrogenase E1, alpha polypeptide | 389 | 0.344 | 0.4017 | Yes |
| 8 | ACOX1 | ACOX1 Entrez, Source | acyl-Coenzyme A oxidase 1, palmitoyl | 429 | 0.329 | 0.4312 | Yes |
| 9 | NR1H3 | NR1H3 Entrez, Source | nuclear receptor subfamily 1, group H, member 3 | 540 | 0.287 | 0.4512 | Yes |
| 10 | AQP7 | AQP7 Entrez, Source | aquaporin 7 | 573 | 0.276 | 0.4759 | Yes |
| 11 | ALAS1 | ALAS1 Entrez, Source | aminolevulinate, delta-, synthase 1 | 839 | 0.215 | 0.4772 | Yes |
| 12 | AK2 | AK2 Entrez, Source | adenylate kinase 2 | 880 | 0.210 | 0.4948 | Yes |
| 13 | TST | TST Entrez, Source | thiosulfate sulfurtransferase (rhodanese) | 926 | 0.203 | 0.5114 | Yes |
| 14 | ENTPD5 | ENTPD5 Entrez, Source | ectonucleoside triphosphate diphosphohydrolase 5 | 1031 | 0.189 | 0.5222 | Yes |
| 15 | DBI | DBI Entrez, Source | diazepam binding inhibitor (GABA receptor modulator, acyl-Coenzyme A binding protein) | 1077 | 0.184 | 0.5370 | Yes |
| 16 | IDH1 | IDH1 Entrez, Source | isocitrate dehydrogenase 1 (NADP+), soluble | 1183 | 0.172 | 0.5460 | Yes |
| 17 | ACADS | ACADS Entrez, Source | acyl-Coenzyme A dehydrogenase, C-2 to C-3 short chain | 1296 | 0.164 | 0.5538 | Yes |
| 18 | RASD1 | RASD1 Entrez, Source | RAS, dexamethasone-induced 1 | 1396 | 0.157 | 0.5618 | Yes |
| 19 | ALAD | ALAD Entrez, Source | aminolevulinate, delta-, dehydratase | 1424 | 0.155 | 0.5751 | Yes |
| 20 | ME1 | ME1 Entrez, Source | malic enzyme 1, NADP(+)-dependent, cytosolic | 1535 | 0.147 | 0.5813 | Yes |
| 21 | DGAT1 | DGAT1 Entrez, Source | diacylglycerol O-acyltransferase homolog 1 (mouse) | 1822 | 0.130 | 0.5725 | No |
| 22 | NFS1 | NFS1 Entrez, Source | NFS1 nitrogen fixation 1 (S. cerevisiae) | 2183 | 0.115 | 0.5568 | No |
| 23 | SCARB1 | SCARB1 Entrez, Source | scavenger receptor class B, member 1 | 2252 | 0.112 | 0.5628 | No |
| 24 | ECH1 | ECH1 Entrez, Source | enoyl Coenzyme A hydratase 1, peroxisomal | 2294 | 0.111 | 0.5706 | No |
| 25 | TALDO1 | TALDO1 Entrez, Source | transaldolase 1 | 2443 | 0.105 | 0.5698 | No |
| 26 | PPARG | PPARG Entrez, Source | peroxisome proliferative activated receptor, gamma | 2538 | 0.101 | 0.5727 | No |
| 27 | SLC2A4 | SLC2A4 Entrez, Source | solute carrier family 2 (facilitated glucose transporter), member 4 | 3091 | 0.082 | 0.5392 | No |
| 28 | ACADM | ACADM Entrez, Source | acyl-Coenzyme A dehydrogenase, C-4 to C-12 straight chain | 4310 | 0.053 | 0.4528 | No |
| 29 | ABCD2 | ABCD2 Entrez, Source | ATP-binding cassette, sub-family D (ALD), member 2 | 4613 | 0.046 | 0.4346 | No |
| 30 | PLA2G6 | PLA2G6 Entrez, Source | phospholipase A2, group VI (cytosolic, calcium-independent) | 6386 | 0.010 | 0.3024 | No |
| 31 | LTC4S | LTC4S Entrez, Source | leukotriene C4 synthase | 6566 | 0.007 | 0.2896 | No |
| 32 | ADIPOQ | ADIPOQ Entrez, Source | adiponectin, C1Q and collagen domain containing | 6570 | 0.007 | 0.2900 | No |
| 33 | CDKN2C | CDKN2C Entrez, Source | cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) | 8322 | -0.030 | 0.1613 | No |
| 34 | IDH3G | IDH3G Entrez, Source | isocitrate dehydrogenase 3 (NAD+) gamma | 8587 | -0.037 | 0.1451 | No |
| 35 | COL15A1 | COL15A1 Entrez, Source | collagen, type XV, alpha 1 | 8592 | -0.037 | 0.1484 | No |
| 36 | HIPK3 | HIPK3 Entrez, Source | homeodomain interacting protein kinase 3 | 10156 | -0.080 | 0.0387 | No |
| 37 | SELENBP1 | SELENBP1 Entrez, Source | selenium binding protein 1 | 10631 | -0.096 | 0.0126 | No |
| 38 | CIB2 | CIB2 Entrez, Source | calcium and integrin binding family member 2 | 11337 | -0.128 | -0.0278 | No |
| 39 | FAM62A | FAM62A Entrez, Source | family with sequence similarity 62 (C2 domain containing), member A | 11823 | -0.159 | -0.0487 | No |
| 40 | TPP2 | TPP2 Entrez, Source | tripeptidyl peptidase II | 12117 | -0.183 | -0.0527 | No |
| 41 | DHRS3 | DHRS3 Entrez, Source | dehydrogenase/reductase (SDR family) member 3 | 12291 | -0.203 | -0.0457 | No |
| 42 | ITGA6 | ITGA6 Entrez, Source | integrin, alpha 6 | 12719 | -0.269 | -0.0513 | No |
| 43 | RGS2 | RGS2 Entrez, Source | regulator of G-protein signalling 2, 24kDa | 13309 | -0.997 | 0.0025 | No |
