Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_single_gel_8d.class.cls #double_gel_8d_versus_single_gel_8d_repos |
| Phenotype | class.cls#double_gel_8d_versus_single_gel_8d_repos |
| Upregulated in class | double_gel_8d |
| GeneSet | TRANSFERASE_ACTIVITY__TRANSFERRING_ACYL_GROUPS |
| Enrichment Score (ES) | 0.5546492 |
| Normalized Enrichment Score (NES) | 1.6575352 |
| Nominal p-value | 0.0040899795 |
| FDR q-value | 0.046115335 |
| FWER p-Value | 1.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | GLYAT | GLYAT Entrez, Source | glycine-N-acyltransferase | 10 | 1.121 | 0.1811 | Yes |
| 2 | ACLY | ACLY Entrez, Source | ATP citrate lyase | 186 | 0.487 | 0.2469 | Yes |
| 3 | HMGCS1 | HMGCS1 Entrez, Source | 3-hydroxy-3-methylglutaryl-Coenzyme A synthase 1 (soluble) | 199 | 0.477 | 0.3233 | Yes |
| 4 | ACAT1 | ACAT1 Entrez, Source | acetyl-Coenzyme A acetyltransferase 1 (acetoacetyl Coenzyme A thiolase) | 430 | 0.329 | 0.3594 | Yes |
| 5 | ACSL3 | ACSL3 Entrez, Source | acyl-CoA synthetase long-chain family member 3 | 546 | 0.284 | 0.3968 | Yes |
| 6 | DGAT2 | DGAT2 Entrez, Source | diacylglycerol O-acyltransferase homolog 2 (mouse) | 627 | 0.259 | 0.4329 | Yes |
| 7 | CPT1A | CPT1A Entrez, Source | carnitine palmitoyltransferase 1A (liver) | 950 | 0.200 | 0.4412 | Yes |
| 8 | AANAT | AANAT Entrez, Source | arylalkylamine N-acetyltransferase | 1198 | 0.171 | 0.4503 | Yes |
| 9 | CPT1B | CPT1B Entrez, Source | carnitine palmitoyltransferase 1B (muscle) | 1278 | 0.165 | 0.4712 | Yes |
| 10 | HADHA | HADHA Entrez, Source | hydroxyacyl-Coenzyme A dehydrogenase/3-ketoacyl-Coenzyme A thiolase/enoyl-Coenzyme A hydratase (trifunctional protein), alpha subunit | 1399 | 0.157 | 0.4876 | Yes |
| 11 | TGM1 | TGM1 Entrez, Source | transglutaminase 1 (K polypeptide epidermal type I, protein-glutamine-gamma-glutamyltransferase) | 1589 | 0.144 | 0.4967 | Yes |
| 12 | GGTLA1 | GGTLA1 Entrez, Source | gamma-glutamyltransferase-like activity 1 | 1598 | 0.143 | 0.5193 | Yes |
| 13 | HADHB | HADHB Entrez, Source | hydroxyacyl-Coenzyme A dehydrogenase/3-ketoacyl-Coenzyme A thiolase/enoyl-Coenzyme A hydratase (trifunctional protein), beta subunit | 1747 | 0.134 | 0.5300 | Yes |
| 14 | DGAT1 | DGAT1 Entrez, Source | diacylglycerol O-acyltransferase homolog 1 (mouse) | 1822 | 0.130 | 0.5455 | Yes |
| 15 | CREBBP | CREBBP Entrez, Source | CREB binding protein (Rubinstein-Taybi syndrome) | 2102 | 0.118 | 0.5436 | Yes |
| 16 | ALAS2 | ALAS2 Entrez, Source | aminolevulinate, delta-, synthase 2 (sideroblastic/hypochromic anemia) | 2203 | 0.114 | 0.5546 | Yes |
| 17 | NAT1 | NAT1 Entrez, Source | N-acetyltransferase 1 (arylamine N-acetyltransferase) | 3018 | 0.084 | 0.5072 | No |
| 18 | F13A1 | F13A1 Entrez, Source | coagulation factor XIII, A1 polypeptide | 3304 | 0.076 | 0.4981 | No |
| 19 | YKT6 | YKT6 Entrez, Source | YKT6 v-SNARE homolog (S. cerevisiae) | 4981 | 0.038 | 0.3784 | No |
| 20 | CS | CS Entrez, Source | citrate synthase | 7513 | -0.013 | 0.1903 | No |
| 21 | TGM2 | TGM2 Entrez, Source | transglutaminase 2 (C polypeptide, protein-glutamine-gamma-glutamyltransferase) | 7842 | -0.020 | 0.1688 | No |
| 22 | GNPAT | GNPAT Entrez, Source | glyceronephosphate O-acyltransferase | 7996 | -0.023 | 0.1611 | No |
| 23 | MYST3 | MYST3 Entrez, Source | MYST histone acetyltransferase (monocytic leukemia) 3 | 8920 | -0.044 | 0.0989 | No |
| 24 | MYST2 | MYST2 Entrez, Source | MYST histone acetyltransferase 2 | 9697 | -0.065 | 0.0512 | No |
| 25 | BRCA2 | BRCA2 Entrez, Source | breast cancer 2, early onset | 10026 | -0.075 | 0.0387 | No |
| 26 | NAT2 | NAT2 Entrez, Source | N-acetyltransferase 2 (arylamine N-acetyltransferase) | 10308 | -0.085 | 0.0314 | No |
| 27 | NCOA3 | NCOA3 Entrez, Source | nuclear receptor coactivator 3 | 10363 | -0.087 | 0.0415 | No |
| 28 | SPTLC1 | SPTLC1 Entrez, Source | serine palmitoyltransferase, long chain base subunit 1 | 10792 | -0.102 | 0.0259 | No |
| 29 | HAT1 | HAT1 Entrez, Source | histone acetyltransferase 1 | 12419 | -0.217 | -0.0610 | No |
| 30 | CROT | CROT Entrez, Source | carnitine O-octanoyltransferase | 12469 | -0.223 | -0.0285 | No |
| 31 | EP300 | EP300 Entrez, Source | E1A binding protein p300 | 12496 | -0.228 | 0.0066 | No |
| 32 | SOAT1 | SOAT1 Entrez, Source | sterol O-acyltransferase (acyl-Coenzyme A: cholesterol acyltransferase) 1 | 12979 | -0.351 | 0.0273 | No |
