Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_single_gel_8d.class.cls #double_gel_8d_versus_single_gel_8d_repos |
| Phenotype | class.cls#double_gel_8d_versus_single_gel_8d_repos |
| Upregulated in class | double_gel_8d |
| GeneSet | TYROSINE_METABOLISM |
| Enrichment Score (ES) | 0.77597815 |
| Normalized Enrichment Score (NES) | 2.1710386 |
| Nominal p-value | 0.0 |
| FDR q-value | 7.965469E-5 |
| FWER p-Value | 0.0040 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | HGD | HGD Entrez, Source | homogentisate 1,2-dioxygenase (homogentisate oxidase) | 17 | 0.930 | 0.1473 | Yes |
| 2 | ADH7 | ADH7 Entrez, Source | alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide | 50 | 0.751 | 0.2648 | Yes |
| 3 | GOT1 | GOT1 Entrez, Source | glutamic-oxaloacetic transaminase 1, soluble (aspartate aminotransferase 1) | 56 | 0.731 | 0.3812 | Yes |
| 4 | ADHFE1 | ADHFE1 Entrez, Source | alcohol dehydrogenase, iron containing, 1 | 89 | 0.633 | 0.4800 | Yes |
| 5 | ABP1 | ABP1 Entrez, Source | amiloride binding protein 1 (amine oxidase (copper-containing)) | 109 | 0.606 | 0.5754 | Yes |
| 6 | ADH1A | ADH1A Entrez, Source | alcohol dehydrogenase 1A (class I), alpha polypeptide | 214 | 0.460 | 0.6411 | Yes |
| 7 | TAT | TAT Entrez, Source | tyrosine aminotransferase | 221 | 0.457 | 0.7136 | Yes |
| 8 | FAH | FAH Entrez, Source | fumarylacetoacetate hydrolase (fumarylacetoacetase) | 277 | 0.416 | 0.7760 | Yes |
| 9 | COMT | COMT Entrez, Source | catechol-O-methyltransferase | 1065 | 0.186 | 0.7466 | No |
| 10 | HPD | HPD Entrez, Source | 4-hydroxyphenylpyruvate dioxygenase | 1252 | 0.167 | 0.7593 | No |
| 11 | MAOB | MAOB Entrez, Source | monoamine oxidase B | 1712 | 0.137 | 0.7467 | No |
| 12 | ADH6 | ADH6 Entrez, Source | alcohol dehydrogenase 6 (class V) | 2402 | 0.107 | 0.7120 | No |
| 13 | DBH | DBH Entrez, Source | dopamine beta-hydroxylase (dopamine beta-monooxygenase) | 2720 | 0.095 | 0.7033 | No |
| 14 | MAOA | MAOA Entrez, Source | monoamine oxidase A | 2802 | 0.091 | 0.7118 | No |
| 15 | DDC | DDC Entrez, Source | dopa decarboxylase (aromatic L-amino acid decarboxylase) | 3130 | 0.081 | 0.7002 | No |
| 16 | ALDH3A1 | ALDH3A1 Entrez, Source | aldehyde dehydrogenase 3 family, memberA1 | 4305 | 0.053 | 0.6204 | No |
| 17 | AOC3 | AOC3 Entrez, Source | amine oxidase, copper containing 3 (vascular adhesion protein 1) | 4870 | 0.040 | 0.5846 | No |
| 18 | PNMT | PNMT Entrez, Source | phenylethanolamine N-methyltransferase | 5236 | 0.033 | 0.5625 | No |
| 19 | ADH4 | ADH4 Entrez, Source | alcohol dehydrogenase 4 (class II), pi polypeptide | 5822 | 0.022 | 0.5220 | No |
| 20 | GOT2 | GOT2 Entrez, Source | glutamic-oxaloacetic transaminase 2, mitochondrial (aspartate aminotransferase 2) | 7234 | -0.007 | 0.4172 | No |
| 21 | TH | TH Entrez, Source | tyrosine hydroxylase | 7455 | -0.011 | 0.4025 | No |
| 22 | TPO | TPO Entrez, Source | thyroid peroxidase | 8032 | -0.024 | 0.3631 | No |
| 23 | AOX1 | AOX1 Entrez, Source | aldehyde oxidase 1 | 8449 | -0.033 | 0.3372 | No |
| 24 | ALDH3B1 | ALDH3B1 Entrez, Source | aldehyde dehydrogenase 3 family, member B1 | 12169 | -0.189 | 0.0881 | No |
