Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_single_gel_8d.class.cls #double_gel_8d_versus_single_gel_8d_repos |
| Phenotype | class.cls#double_gel_8d_versus_single_gel_8d_repos |
| Upregulated in class | double_gel_8d |
| GeneSet | UEDA_MOUSE_LIVER |
| Enrichment Score (ES) | 0.5055669 |
| Normalized Enrichment Score (NES) | 1.8839798 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.006356214 |
| FWER p-Value | 0.532 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | CYP8B1 | CYP8B1 Entrez, Source | cytochrome P450, family 8, subfamily B, polypeptide 1 | 14 | 1.030 | 0.0438 | Yes |
| 2 | IDI1 | IDI1 Entrez, Source | isopentenyl-diphosphate delta isomerase 1 | 110 | 0.603 | 0.0629 | Yes |
| 3 | ELOVL6 | ELOVL6 Entrez, Source | ELOVL family member 6, elongation of long chain fatty acids (FEN1/Elo2, SUR4/Elo3-like, yeast) | 120 | 0.589 | 0.0879 | Yes |
| 4 | ASL | ASL Entrez, Source | argininosuccinate lyase | 122 | 0.586 | 0.1134 | Yes |
| 5 | USP2 | USP2 Entrez, Source | ubiquitin specific peptidase 2 | 134 | 0.557 | 0.1368 | Yes |
| 6 | PPP1R3C | PPP1R3C Entrez, Source | protein phosphatase 1, regulatory (inhibitor) subunit 3C | 146 | 0.543 | 0.1596 | Yes |
| 7 | AQP9 | AQP9 Entrez, Source | aquaporin 9 | 197 | 0.479 | 0.1767 | Yes |
| 8 | HMGCS1 | HMGCS1 Entrez, Source | 3-hydroxy-3-methylglutaryl-Coenzyme A synthase 1 (soluble) | 199 | 0.477 | 0.1974 | Yes |
| 9 | FASN | FASN Entrez, Source | fatty acid synthase | 213 | 0.460 | 0.2165 | Yes |
| 10 | AK3L1 | AK3L1 Entrez, Source | adenylate kinase 3-like 1 | 232 | 0.450 | 0.2348 | Yes |
| 11 | FDPS | FDPS Entrez, Source | farnesyl diphosphate synthase (farnesyl pyrophosphate synthetase, dimethylallyltranstransferase, geranyltranstransferase) | 315 | 0.386 | 0.2454 | Yes |
| 12 | DHCR7 | DHCR7 Entrez, Source | 7-dehydrocholesterol reductase | 333 | 0.375 | 0.2604 | Yes |
| 13 | BNIP3 | BNIP3 Entrez, Source | BCL2/adenovirus E1B 19kDa interacting protein 3 | 356 | 0.360 | 0.2745 | Yes |
| 14 | POR | POR Entrez, Source | P450 (cytochrome) oxidoreductase | 384 | 0.346 | 0.2875 | Yes |
| 15 | HERPUD1 | HERPUD1 Entrez, Source | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | 425 | 0.331 | 0.2989 | Yes |
| 16 | ABCB4 | ABCB4 Entrez, Source | ATP-binding cassette, sub-family B (MDR/TAP), member 4 | 426 | 0.330 | 0.3133 | Yes |
| 17 | HMGCR | HMGCR Entrez, Source | 3-hydroxy-3-methylglutaryl-Coenzyme A reductase | 434 | 0.327 | 0.3270 | Yes |
| 18 | LGALS9 | LGALS9 Entrez, Source | lectin, galactoside-binding, soluble, 9 (galectin 9) | 440 | 0.324 | 0.3408 | Yes |
| 19 | FOXA3 | FOXA3 Entrez, Source | forkhead box A3 | 492 | 0.303 | 0.3501 | Yes |
| 20 | TMEM150 | TMEM150 Entrez, Source | transmembrane protein 150 | 496 | 0.301 | 0.3630 | Yes |
| 21 | CYB5B | CYB5B Entrez, Source | cytochrome b5 type B (outer mitochondrial membrane) | 505 | 0.298 | 0.3754 | Yes |
| 22 | ATF5 | ATF5 Entrez, Source | activating transcription factor 5 | 511 | 0.296 | 0.3879 | Yes |
| 23 | CD9 | CD9 Entrez, Source | CD9 molecule | 512 | 0.295 | 0.4008 | Yes |
| 24 | SLC11A2 | SLC11A2 Entrez, Source | solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2 | 538 | 0.287 | 0.4114 | Yes |
| 25 | BHLHB2 | BHLHB2 Entrez, Source | basic helix-loop-helix domain containing, class B, 2 | 581 | 0.272 | 0.4201 | Yes |
| 26 | ERBB3 | ERBB3 Entrez, Source | v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian) | 595 | 0.269 | 0.4309 | Yes |
| 27 | SLC37A4 | SLC37A4 Entrez, Source | solute carrier family 37 (glycerol-6-phosphate transporter), member 4 | 675 | 0.246 | 0.4356 | Yes |
| 28 | SERPINF2 | SERPINF2 Entrez, Source | serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2 | 719 | 0.235 | 0.4426 | Yes |
| 29 | PPARA | PPARA Entrez, Source | peroxisome proliferative activated receptor, alpha | 732 | 0.231 | 0.4518 | Yes |
| 30 | APOA5 | APOA5 Entrez, Source | apolipoprotein A-V | 827 | 0.217 | 0.4541 | Yes |
| 31 | ALAS1 | ALAS1 Entrez, Source | aminolevulinate, delta-, synthase 1 | 839 | 0.215 | 0.4626 | Yes |
| 32 | CEBPB | CEBPB Entrez, Source | CCAAT/enhancer binding protein (C/EBP), beta | 862 | 0.212 | 0.4702 | Yes |
| 33 | AK2 | AK2 Entrez, Source | adenylate kinase 2 | 880 | 0.210 | 0.4781 | Yes |
| 34 | RCL1 | RCL1 Entrez, Source | RNA terminal phosphate cyclase-like 1 | 904 | 0.206 | 0.4853 | Yes |
| 35 | CYP7A1 | CYP7A1 Entrez, Source | cytochrome P450, family 7, subfamily A, polypeptide 1 | 934 | 0.202 | 0.4919 | Yes |
| 36 | CPT1A | CPT1A Entrez, Source | carnitine palmitoyltransferase 1A (liver) | 950 | 0.200 | 0.4995 | Yes |
| 37 | CHKA | CHKA Entrez, Source | choline kinase alpha | 984 | 0.196 | 0.5056 | Yes |
| 38 | CES3 | CES3 Entrez, Source | carboxylesterase 3 (brain) | 1130 | 0.179 | 0.5024 | No |
| 39 | AQP8 | AQP8 Entrez, Source | aquaporin 8 | 1275 | 0.166 | 0.4987 | No |
| 40 | NFIL3 | NFIL3 Entrez, Source | nuclear factor, interleukin 3 regulated | 1319 | 0.163 | 0.5026 | No |
| 41 | CEBPA | CEBPA Entrez, Source | CCAAT/enhancer binding protein (C/EBP), alpha | 1386 | 0.158 | 0.5045 | No |
| 42 | CLDN1 | CLDN1 Entrez, Source | claudin 1 | 1554 | 0.145 | 0.4982 | No |
| 43 | ARL6IP2 | ARL6IP2 Entrez, Source | ADP-ribosylation factor-like 6 interacting protein 2 | 1624 | 0.142 | 0.4992 | No |
| 44 | ELOVL5 | ELOVL5 Entrez, Source | ELOVL family member 5, elongation of long chain fatty acids (FEN1/Elo2, SUR4/Elo3-like, yeast) | 2393 | 0.107 | 0.4458 | No |
| 45 | ARNTL | ARNTL Entrez, Source | aryl hydrocarbon receptor nuclear translocator-like | 2555 | 0.101 | 0.4380 | No |
| 46 | ST3GAL5 | ST3GAL5 Entrez, Source | ST3 beta-galactoside alpha-2,3-sialyltransferase 5 | 2616 | 0.099 | 0.4378 | No |
| 47 | PCSK4 | PCSK4 Entrez, Source | proprotein convertase subtilisin/kexin type 4 | 2628 | 0.098 | 0.4412 | No |
| 48 | TSPAN4 | TSPAN4 Entrez, Source | tetraspanin 4 | 2691 | 0.096 | 0.4407 | No |
| 49 | TARS | TARS Entrez, Source | threonyl-tRNA synthetase | 2704 | 0.095 | 0.4440 | No |
| 50 | MKNK2 | MKNK2 Entrez, Source | MAP kinase interacting serine/threonine kinase 2 | 2879 | 0.089 | 0.4347 | No |
| 51 | SLC2A2 | SLC2A2 Entrez, Source | solute carrier family 2 (facilitated glucose transporter), member 2 | 2969 | 0.086 | 0.4317 | No |
| 52 | MAPK14 | MAPK14 Entrez, Source | mitogen-activated protein kinase 14 | 2979 | 0.086 | 0.4348 | No |
| 53 | FBXO8 | FBXO8 Entrez, Source | F-box protein 8 | 3404 | 0.074 | 0.4059 | No |
| 54 | MAP2K3 | MAP2K3 Entrez, Source | mitogen-activated protein kinase kinase 3 | 3755 | 0.065 | 0.3823 | No |
| 55 | PNRC1 | PNRC1 Entrez, Source | proline-rich nuclear receptor coactivator 1 | 4047 | 0.058 | 0.3629 | No |
| 56 | PCAF | PCAF Entrez, Source | p300/CBP-associated factor | 4209 | 0.055 | 0.3531 | No |
| 57 | BTG1 | BTG1 Entrez, Source | B-cell translocation gene 1, anti-proliferative | 4354 | 0.052 | 0.3445 | No |
| 58 | PDIA4 | PDIA4 Entrez, Source | protein disulfide isomerase family A, member 4 | 4372 | 0.051 | 0.3454 | No |
| 59 | IL4R | IL4R Entrez, Source | interleukin 4 receptor | 4588 | 0.047 | 0.3312 | No |
| 60 | COL18A1 | COL18A1 Entrez, Source | collagen, type XVIII, alpha 1 | 4715 | 0.044 | 0.3236 | No |
| 61 | LITAF | LITAF Entrez, Source | lipopolysaccharide-induced TNF factor | 4957 | 0.039 | 0.3071 | No |
| 62 | SQSTM1 | SQSTM1 Entrez, Source | sequestosome 1 | 5161 | 0.035 | 0.2932 | No |
| 63 | TFPI2 | TFPI2 Entrez, Source | tissue factor pathway inhibitor 2 | 5317 | 0.032 | 0.2829 | No |
| 64 | PSEN2 | PSEN2 Entrez, Source | presenilin 2 (Alzheimer disease 4) | 5670 | 0.024 | 0.2574 | No |
| 65 | ADH4 | ADH4 Entrez, Source | alcohol dehydrogenase 4 (class II), pi polypeptide | 5822 | 0.022 | 0.2469 | No |
| 66 | FKBP4 | FKBP4 Entrez, Source | FK506 binding protein 4, 59kDa | 5864 | 0.021 | 0.2447 | No |
| 67 | LSR | LSR Entrez, Source | lipolysis stimulated lipoprotein receptor | 6298 | 0.012 | 0.2125 | No |
| 68 | CRY1 | CRY1 Entrez, Source | cryptochrome 1 (photolyase-like) | 6356 | 0.010 | 0.2087 | No |
| 69 | GNE | GNE Entrez, Source | glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase | 6397 | 0.010 | 0.2061 | No |
| 70 | NR1D1 | NR1D1 Entrez, Source | nuclear receptor subfamily 1, group D, member 1 | 6399 | 0.010 | 0.2064 | No |
| 71 | BRI3 | BRI3 Entrez, Source | brain protein I3 | 7084 | -0.004 | 0.1549 | No |
| 72 | DNAJB11 | DNAJB11 Entrez, Source | DnaJ (Hsp40) homolog, subfamily B, member 11 | 7530 | -0.013 | 0.1219 | No |
| 73 | NR1D2 | NR1D2 Entrez, Source | nuclear receptor subfamily 1, group D, member 2 | 7919 | -0.021 | 0.0935 | No |
| 74 | DAZAP2 | DAZAP2 Entrez, Source | DAZ associated protein 2 | 8158 | -0.027 | 0.0767 | No |
| 75 | HNRPAB | HNRPAB Entrez, Source | heterogeneous nuclear ribonucleoprotein A/B | 8280 | -0.029 | 0.0688 | No |
| 76 | PER2 | PER2 Entrez, Source | period homolog 2 (Drosophila) | 8421 | -0.033 | 0.0597 | No |
| 77 | SLC29A1 | SLC29A1 Entrez, Source | solute carrier family 29 (nucleoside transporters), member 1 | 9613 | -0.063 | -0.0276 | No |
| 78 | GALT | GALT Entrez, Source | galactose-1-phosphate uridylyltransferase | 9817 | -0.069 | -0.0399 | No |
| 79 | KLF9 | KLF9 Entrez, Source | Kruppel-like factor 9 | 10129 | -0.079 | -0.0599 | No |
| 80 | RBMS1 | RBMS1 Entrez, Source | RNA binding motif, single stranded interacting protein 1 | 10149 | -0.080 | -0.0579 | No |
| 81 | HES6 | HES6 Entrez, Source | hairy and enhancer of split 6 (Drosophila) | 10168 | -0.080 | -0.0558 | No |
| 82 | MESDC2 | MESDC2 Entrez, Source | mesoderm development candidate 2 | 10392 | -0.088 | -0.0688 | No |
| 83 | DNAJA1 | DNAJA1 Entrez, Source | DnaJ (Hsp40) homolog, subfamily A, member 1 | 10557 | -0.094 | -0.0771 | No |
| 84 | MGEA5 | MGEA5 Entrez, Source | meningioma expressed antigen 5 (hyaluronidase) | 10610 | -0.095 | -0.0769 | No |
| 85 | HSP90AA1 | HSP90AA1 Entrez, Source | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 10648 | -0.097 | -0.0754 | No |
| 86 | SLC9A3R1 | SLC9A3R1 Entrez, Source | solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1 | 10921 | -0.108 | -0.0913 | No |
| 87 | FDX1 | FDX1 Entrez, Source | ferredoxin 1 | 10969 | -0.110 | -0.0900 | No |
| 88 | PLEKHC1 | PLEKHC1 Entrez, Source | pleckstrin homology domain containing, family C (with FERM domain) member 1 | 11076 | -0.115 | -0.0930 | No |
| 89 | ANP32A | ANP32A Entrez, Source | acidic (leucine-rich) nuclear phosphoprotein 32 family, member A | 11345 | -0.129 | -0.1077 | No |
| 90 | CD47 | CD47 Entrez, Source | CD47 molecule | 11473 | -0.136 | -0.1113 | No |
| 91 | THRAP3 | THRAP3 Entrez, Source | thyroid hormone receptor associated protein 3 | 11514 | -0.138 | -0.1083 | No |
| 92 | CHD4 | CHD4 Entrez, Source | chromodomain helicase DNA binding protein 4 | 11593 | -0.143 | -0.1080 | No |
| 93 | DYNLL1 | DYNLL1 Entrez, Source | dynein, light chain, LC8-type 1 | 11702 | -0.150 | -0.1096 | No |
| 94 | AVPR1A | AVPR1A Entrez, Source | arginine vasopressin receptor 1A | 12016 | -0.174 | -0.1257 | No |
| 95 | ONECUT1 | ONECUT1 Entrez, Source | one cut domain, family member 1 | 12048 | -0.177 | -0.1203 | No |
| 96 | DHRS3 | DHRS3 Entrez, Source | dehydrogenase/reductase (SDR family) member 3 | 12291 | -0.203 | -0.1297 | No |
| 97 | ID2 | ID2 Entrez, Source | inhibitor of DNA binding 2, dominant negative helix-loop-helix protein | 12405 | -0.215 | -0.1289 | No |
| 98 | S100A10 | S100A10 Entrez, Source | S100 calcium binding protein A10 | 12432 | -0.219 | -0.1213 | No |
| 99 | ALCAM | ALCAM Entrez, Source | activated leukocyte cell adhesion molecule | 12557 | -0.237 | -0.1204 | No |
| 100 | TUBB | TUBB Entrez, Source | tubulin, beta | 12961 | -0.344 | -0.1358 | No |
| 101 | LMO7 | LMO7 Entrez, Source | LIM domain 7 | 13121 | -0.443 | -0.1285 | No |
| 102 | FGF1 | FGF1 Entrez, Source | fibroblast growth factor 1 (acidic) | 13192 | -0.544 | -0.1101 | No |
| 103 | CRIP2 | CRIP2 Entrez, Source | cysteine-rich protein 2 | 13214 | -0.582 | -0.0863 | No |
| 104 | TSC22D1 | TSC22D1 Entrez, Source | TSC22 domain family, member 1 | 13246 | -0.674 | -0.0593 | No |
| 105 | COL4A1 | COL4A1 Entrez, Source | collagen, type IV, alpha 1 | 13269 | -0.760 | -0.0278 | No |
| 106 | F2R | F2R Entrez, Source | coagulation factor II (thrombin) receptor | 13270 | -0.762 | 0.0054 | No |
