Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_single_gel_8d.class.cls #double_gel_8d_versus_single_gel_8d_repos |
| Phenotype | class.cls#double_gel_8d_versus_single_gel_8d_repos |
| Upregulated in class | single_gel_8d |
| GeneSet | UVC_TTD_4HR_DN |
| Enrichment Score (ES) | -0.51611984 |
| Normalized Enrichment Score (NES) | -1.9077401 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.021239998 |
| FWER p-Value | 0.428 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | PPAP2B | PPAP2B Entrez, Source | phosphatidic acid phosphatase type 2B | 205 | 0.467 | 0.0100 | No |
| 2 | MSH3 | MSH3 Entrez, Source | mutS homolog 3 (E. coli) | 444 | 0.323 | 0.0097 | No |
| 3 | BHLHB2 | BHLHB2 Entrez, Source | basic helix-loop-helix domain containing, class B, 2 | 581 | 0.272 | 0.0143 | No |
| 4 | PRKCA | PRKCA Entrez, Source | protein kinase C, alpha | 736 | 0.230 | 0.0152 | No |
| 5 | IFRD1 | IFRD1 Entrez, Source | interferon-related developmental regulator 1 | 837 | 0.215 | 0.0194 | No |
| 6 | PTPN2 | PTPN2 Entrez, Source | protein tyrosine phosphatase, non-receptor type 2 | 922 | 0.204 | 0.0242 | No |
| 7 | IL1RAP | IL1RAP Entrez, Source | interleukin 1 receptor accessory protein | 1037 | 0.188 | 0.0259 | No |
| 8 | STK39 | STK39 Entrez, Source | serine threonine kinase 39 (STE20/SPS1 homolog, yeast) | 1121 | 0.180 | 0.0294 | No |
| 9 | PRKCBP1 | PRKCBP1 Entrez, Source | protein kinase C binding protein 1 | 1676 | 0.138 | -0.0049 | No |
| 10 | FYN | FYN Entrez, Source | FYN oncogene related to SRC, FGR, YES | 1691 | 0.137 | 0.0015 | No |
| 11 | CREBBP | CREBBP Entrez, Source | CREB binding protein (Rubinstein-Taybi syndrome) | 2102 | 0.118 | -0.0230 | No |
| 12 | TMEM23 | TMEM23 Entrez, Source | transmembrane protein 23 | 2473 | 0.104 | -0.0454 | No |
| 13 | IGF2BP3 | IGF2BP3 Entrez, Source | insulin-like growth factor 2 mRNA binding protein 3 | 2530 | 0.102 | -0.0440 | No |
| 14 | PEX14 | PEX14 Entrez, Source | peroxisomal biogenesis factor 14 | 2722 | 0.095 | -0.0533 | No |
| 15 | SIPA1L1 | SIPA1L1 Entrez, Source | signal-induced proliferation-associated 1 like 1 | 2878 | 0.089 | -0.0602 | No |
| 16 | RGS7 | RGS7 Entrez, Source | regulator of G-protein signalling 7 | 3011 | 0.085 | -0.0655 | No |
| 17 | DLC1 | DLC1 Entrez, Source | deleted in liver cancer 1 | 3032 | 0.084 | -0.0625 | No |
| 18 | HOMER1 | HOMER1 Entrez, Source | homer homolog 1 (Drosophila) | 3268 | 0.077 | -0.0760 | No |
| 19 | CEP350 | CEP350 Entrez, Source | centrosomal protein 350kDa | 3715 | 0.066 | -0.1062 | No |
| 20 | ZHX3 | ZHX3 Entrez, Source | zinc fingers and homeoboxes 3 | 3874 | 0.063 | -0.1147 | No |
| 21 | FGF5 | FGF5 Entrez, Source | fibroblast growth factor 5 | 3936 | 0.061 | -0.1160 | No |
| 22 | FGF2 | FGF2 Entrez, Source | fibroblast growth factor 2 (basic) | 4096 | 0.057 | -0.1249 | No |
| 23 | CNOT4 | CNOT4 Entrez, Source | CCR4-NOT transcription complex, subunit 4 | 4218 | 0.055 | -0.1310 | No |
| 24 | SPOP | SPOP Entrez, Source | speckle-type POZ protein | 4316 | 0.052 | -0.1355 | No |
| 25 | ARNT2 | ARNT2 Entrez, Source | aryl-hydrocarbon receptor nuclear translocator 2 | 4741 | 0.043 | -0.1652 | No |
| 26 | EDG2 | EDG2 Entrez, Source | endothelial differentiation, lysophosphatidic acid G-protein-coupled receptor, 2 | 4894 | 0.040 | -0.1745 | No |
| 27 | EIF4E | EIF4E Entrez, Source | eukaryotic translation initiation factor 4E | 5186 | 0.034 | -0.1947 | No |
| 28 | ORC2L | ORC2L Entrez, Source | origin recognition complex, subunit 2-like (yeast) | 5273 | 0.032 | -0.1994 | No |
| 29 | BARD1 | BARD1 Entrez, Source | BRCA1 associated RING domain 1 | 5278 | 0.032 | -0.1980 | No |
| 30 | ATXN1 | ATXN1 Entrez, Source | ataxin 1 | 5443 | 0.029 | -0.2088 | No |
| 31 | SLIT1 | SLIT1 Entrez, Source | slit homolog 1 (Drosophila) | 5766 | 0.023 | -0.2319 | No |
| 32 | LYN | LYN Entrez, Source | v-yes-1 Yamaguchi sarcoma viral related oncogene homolog | 5855 | 0.021 | -0.2374 | No |
| 33 | ACVR2A | ACVR2A Entrez, Source | activin A receptor, type IIA | 5863 | 0.021 | -0.2368 | No |
| 34 | PTPN12 | PTPN12 Entrez, Source | protein tyrosine phosphatase, non-receptor type 12 | 6058 | 0.017 | -0.2505 | No |
| 35 | CRY1 | CRY1 Entrez, Source | cryptochrome 1 (photolyase-like) | 6356 | 0.010 | -0.2724 | No |
| 36 | SYNJ2 | SYNJ2 Entrez, Source | synaptojanin 2 | 6475 | 0.008 | -0.2809 | No |
| 37 | HNRPDL | HNRPDL Entrez, Source | heterogeneous nuclear ribonucleoprotein D-like | 6556 | 0.007 | -0.2866 | No |
| 38 | UBL3 | UBL3 Entrez, Source | ubiquitin-like 3 | 6577 | 0.006 | -0.2877 | No |
| 39 | SLC4A7 | SLC4A7 Entrez, Source | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | 6666 | 0.005 | -0.2941 | No |
| 40 | VEGFC | VEGFC Entrez, Source | vascular endothelial growth factor C | 6727 | 0.004 | -0.2985 | No |
| 41 | CUTL1 | CUTL1 Entrez, Source | cut-like 1, CCAAT displacement protein (Drosophila) | 6916 | -0.000 | -0.3127 | No |
| 42 | ATP2B1 | ATP2B1 Entrez, Source | ATPase, Ca++ transporting, plasma membrane 1 | 6925 | -0.000 | -0.3133 | No |
| 43 | MGAT5 | MGAT5 Entrez, Source | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 6976 | -0.002 | -0.3170 | No |
| 44 | MAPK6 | MAPK6 Entrez, Source | mitogen-activated protein kinase 6 | 7114 | -0.004 | -0.3271 | No |
| 45 | AFAP | AFAP Entrez, Source | - | 7458 | -0.011 | -0.3524 | No |
| 46 | XRCC4 | XRCC4 Entrez, Source | X-ray repair complementing defective repair in Chinese hamster cells 4 | 7672 | -0.016 | -0.3677 | No |
| 47 | PPP1R12A | PPP1R12A Entrez, Source | protein phosphatase 1, regulatory (inhibitor) subunit 12A | 7740 | -0.017 | -0.3718 | No |
| 48 | BMP2K | BMP2K Entrez, Source | BMP2 inducible kinase | 7875 | -0.020 | -0.3808 | No |
| 49 | NIPBL | NIPBL Entrez, Source | Nipped-B homolog (Drosophila) | 8250 | -0.029 | -0.4075 | No |
| 50 | NUP98 | NUP98 Entrez, Source | nucleoporin 98kDa | 8376 | -0.032 | -0.4152 | No |
| 51 | KLF10 | KLF10 Entrez, Source | Kruppel-like factor 10 | 8626 | -0.037 | -0.4320 | No |
| 52 | DYRK1A | DYRK1A Entrez, Source | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 8768 | -0.040 | -0.4405 | No |
| 53 | GSK3B | GSK3B Entrez, Source | glycogen synthase kinase 3 beta | 8782 | -0.040 | -0.4393 | No |
| 54 | MYST3 | MYST3 Entrez, Source | MYST histone acetyltransferase (monocytic leukemia) 3 | 8920 | -0.044 | -0.4472 | No |
| 55 | ARIH1 | ARIH1 Entrez, Source | ariadne homolog, ubiquitin-conjugating enzyme E2 binding protein, 1 (Drosophila) | 9421 | -0.058 | -0.4819 | No |
| 56 | ARHGEF7 | ARHGEF7 Entrez, Source | Rho guanine nucleotide exchange factor (GEF) 7 | 9623 | -0.063 | -0.4936 | No |
| 57 | PKN2 | PKN2 Entrez, Source | protein kinase N2 | 9626 | -0.063 | -0.4903 | No |
| 58 | GNAQ | GNAQ Entrez, Source | guanine nucleotide binding protein (G protein), q polypeptide | 9655 | -0.064 | -0.4889 | No |
| 59 | HAS2 | HAS2 Entrez, Source | hyaluronan synthase 2 | 9840 | -0.070 | -0.4991 | No |
| 60 | STRN3 | STRN3 Entrez, Source | striatin, calmodulin binding protein 3 | 9894 | -0.071 | -0.4992 | No |
| 61 | RSN | RSN Entrez, Source | restin (Reed-Steinberg cell-expressed intermediate filament-associated protein) | 9993 | -0.074 | -0.5025 | No |
| 62 | ZRF1 | ZRF1 Entrez, Source | zuotin related factor 1 | 10048 | -0.076 | -0.5024 | No |
| 63 | WDR7 | WDR7 Entrez, Source | WD repeat domain 7 | 10063 | -0.077 | -0.4993 | No |
| 64 | ID1 | ID1 Entrez, Source | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein | 10098 | -0.078 | -0.4976 | No |
| 65 | EGFR | EGFR Entrez, Source | epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian) | 10171 | -0.080 | -0.4987 | No |
| 66 | ITSN1 | ITSN1 Entrez, Source | intersectin 1 (SH3 domain protein) | 10184 | -0.081 | -0.4952 | No |
| 67 | MAP2K4 | MAP2K4 Entrez, Source | mitogen-activated protein kinase kinase 4 | 10267 | -0.084 | -0.4968 | No |
| 68 | RBM16 | RBM16 Entrez, Source | RNA binding motif protein 16 | 10272 | -0.084 | -0.4925 | No |
| 69 | NCOA3 | NCOA3 Entrez, Source | nuclear receptor coactivator 3 | 10363 | -0.087 | -0.4946 | No |
| 70 | CNOT2 | CNOT2 Entrez, Source | CCR4-NOT transcription complex, subunit 2 | 10411 | -0.089 | -0.4933 | No |
| 71 | RBM39 | RBM39 Entrez, Source | RNA binding motif protein 39 | 10593 | -0.095 | -0.5018 | No |
| 72 | PHLPP | PHLPP Entrez, Source | PH domain and leucine rich repeat protein phosphatase | 10612 | -0.095 | -0.4979 | No |
| 73 | MDN1 | MDN1 Entrez, Source | MDN1, midasin homolog (yeast) | 10751 | -0.101 | -0.5029 | No |
| 74 | PAFAH1B1 | PAFAH1B1 Entrez, Source | platelet-activating factor acetylhydrolase, isoform Ib, alpha subunit 45kDa | 10819 | -0.104 | -0.5023 | No |
| 75 | MNAT1 | MNAT1 Entrez, Source | menage a trois homolog 1, cyclin H assembly factor (Xenopus laevis) | 10832 | -0.104 | -0.4975 | No |
| 76 | CBLB | CBLB Entrez, Source | Cas-Br-M (murine) ecotropic retroviral transforming sequence b | 10938 | -0.109 | -0.4995 | No |
| 77 | PLEKHC1 | PLEKHC1 Entrez, Source | pleckstrin homology domain containing, family C (with FERM domain) member 1 | 11076 | -0.115 | -0.5036 | No |
| 78 | PPP2R2A | PPP2R2A Entrez, Source | protein phosphatase 2 (formerly 2A), regulatory subunit B (PR 52), alpha isoform | 11243 | -0.124 | -0.5094 | Yes |
| 79 | CTGF | CTGF Entrez, Source | connective tissue growth factor | 11278 | -0.125 | -0.5051 | Yes |
| 80 | NUP153 | NUP153 Entrez, Source | nucleoporin 153kDa | 11280 | -0.126 | -0.4983 | Yes |
| 81 | ZNF148 | ZNF148 Entrez, Source | zinc finger protein 148 | 11301 | -0.126 | -0.4929 | Yes |
| 82 | CASP8 | CASP8 Entrez, Source | caspase 8, apoptosis-related cysteine peptidase | 11401 | -0.131 | -0.4932 | Yes |
| 83 | STK3 | STK3 Entrez, Source | serine/threonine kinase 3 (STE20 homolog, yeast) | 11428 | -0.133 | -0.4879 | Yes |
| 84 | TUBGCP3 | TUBGCP3 Entrez, Source | tubulin, gamma complex associated protein 3 | 11484 | -0.136 | -0.4846 | Yes |
| 85 | MARCH7 | MARCH7 Entrez, Source | membrane-associated ring finger (C3HC4) 7 | 11511 | -0.138 | -0.4791 | Yes |
| 86 | SMAD3 | SMAD3 Entrez, Source | SMAD, mothers against DPP homolog 3 (Drosophila) | 11527 | -0.139 | -0.4726 | Yes |
| 87 | ATF2 | ATF2 Entrez, Source | activating transcription factor 2 | 11597 | -0.143 | -0.4700 | Yes |
| 88 | FUBP1 | FUBP1 Entrez, Source | far upstream element (FUSE) binding protein 1 | 11776 | -0.155 | -0.4750 | Yes |
| 89 | PUM2 | PUM2 Entrez, Source | pumilio homolog 2 (Drosophila) | 11991 | -0.172 | -0.4818 | Yes |
| 90 | ACVR1 | ACVR1 Entrez, Source | activin A receptor, type I | 11998 | -0.173 | -0.4728 | Yes |
| 91 | PARG | PARG Entrez, Source | poly (ADP-ribose) glycohydrolase | 12022 | -0.175 | -0.4650 | Yes |
| 92 | TLE4 | TLE4 Entrez, Source | transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila) | 12093 | -0.181 | -0.4604 | Yes |
| 93 | ABI1 | ABI1 Entrez, Source | abl-interactor 1 | 12095 | -0.181 | -0.4505 | Yes |
| 94 | TSPAN5 | TSPAN5 Entrez, Source | tetraspanin 5 | 12120 | -0.183 | -0.4423 | Yes |
| 95 | ROCK2 | ROCK2 Entrez, Source | Rho-associated, coiled-coil containing protein kinase 2 | 12156 | -0.187 | -0.4347 | Yes |
| 96 | MTMR3 | MTMR3 Entrez, Source | myotubularin related protein 3 | 12309 | -0.205 | -0.4350 | Yes |
| 97 | OGT | OGT Entrez, Source | O-linked N-acetylglucosamine (GlcNAc) transferase (UDP-N-acetylglucosamine:polypeptide-N-acetylglucosaminyl transferase) | 12392 | -0.214 | -0.4295 | Yes |
| 98 | PTK2 | PTK2 Entrez, Source | PTK2 protein tyrosine kinase 2 | 12413 | -0.216 | -0.4192 | Yes |
| 99 | MID1 | MID1 Entrez, Source | midline 1 (Opitz/BBB syndrome) | 12463 | -0.223 | -0.4108 | Yes |
| 100 | REV3L | REV3L Entrez, Source | REV3-like, catalytic subunit of DNA polymerase zeta (yeast) | 12493 | -0.227 | -0.4005 | Yes |
| 101 | PRIM2A | PRIM2A Entrez, Source | primase, polypeptide 2A, 58kDa | 12498 | -0.229 | -0.3883 | Yes |
| 102 | CLASP2 | CLASP2 Entrez, Source | cytoplasmic linker associated protein 2 | 12533 | -0.233 | -0.3782 | Yes |
| 103 | TRIO | TRIO Entrez, Source | triple functional domain (PTPRF interacting) | 12599 | -0.245 | -0.3697 | Yes |
| 104 | KIF2A | KIF2A Entrez, Source | kinesin heavy chain member 2A | 12626 | -0.249 | -0.3581 | Yes |
| 105 | PTPRK | PTPRK Entrez, Source | protein tyrosine phosphatase, receptor type, K | 12652 | -0.254 | -0.3461 | Yes |
| 106 | SPBC25 | SPBC25 Entrez, Source | spindle pole body component 25 homolog (S. cerevisiae) | 12653 | -0.254 | -0.3322 | Yes |
| 107 | RRAS2 | RRAS2 Entrez, Source | related RAS viral (r-ras) oncogene homolog 2 | 12665 | -0.257 | -0.3190 | Yes |
| 108 | MTF2 | MTF2 Entrez, Source | metal response element binding transcription factor 2 | 12667 | -0.258 | -0.3050 | Yes |
| 109 | TCF12 | TCF12 Entrez, Source | transcription factor 12 (HTF4, helix-loop-helix transcription factors 4) | 12690 | -0.262 | -0.2923 | Yes |
| 110 | UGCG | UGCG Entrez, Source | UDP-glucose ceramide glucosyltransferase | 12723 | -0.270 | -0.2800 | Yes |
| 111 | CEP170 | CEP170 Entrez, Source | centrosomal protein 170kDa | 12737 | -0.273 | -0.2661 | Yes |
| 112 | TGFB2 | TGFB2 Entrez, Source | transforming growth factor, beta 2 | 12832 | -0.296 | -0.2570 | Yes |
| 113 | PCTK2 | PCTK2 Entrez, Source | PCTAIRE protein kinase 2 | 12886 | -0.316 | -0.2438 | Yes |
| 114 | CLASP1 | CLASP1 Entrez, Source | cytoplasmic linker associated protein 1 | 12909 | -0.326 | -0.2276 | Yes |
| 115 | SCHIP1 | SCHIP1 Entrez, Source | schwannomin interacting protein 1 | 12910 | -0.326 | -0.2098 | Yes |
| 116 | RUNX1 | RUNX1 Entrez, Source | runt-related transcription factor 1 (acute myeloid leukemia 1; aml1 oncogene) | 12949 | -0.338 | -0.1942 | Yes |
| 117 | ZNF292 | ZNF292 Entrez, Source | zinc finger protein 292 | 13045 | -0.393 | -0.1799 | Yes |
| 118 | GNAI1 | GNAI1 Entrez, Source | guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1 | 13055 | -0.401 | -0.1587 | Yes |
| 119 | GULP1 | GULP1 Entrez, Source | GULP, engulfment adaptor PTB domain containing 1 | 13058 | -0.404 | -0.1367 | Yes |
| 120 | PARD3 | PARD3 Entrez, Source | par-3 partitioning defective 3 homolog (C. elegans) | 13124 | -0.445 | -0.1173 | Yes |
| 121 | CTBP2 | CTBP2 Entrez, Source | C-terminal binding protein 2 | 13212 | -0.580 | -0.0922 | Yes |
| 122 | PPP2R3A | PPP2R3A Entrez, Source | protein phosphatase 2 (formerly 2A), regulatory subunit B'', alpha | 13267 | -0.745 | -0.0555 | Yes |
| 123 | F3 | F3 Entrez, Source | coagulation factor III (thromboplastin, tissue factor) | 13324 | -1.119 | 0.0014 | Yes |
