Datasetdouble_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls
#double_gel_8d_versus_single_gel_8d.class.cls
#double_gel_8d_versus_single_gel_8d_repos
Phenotypeclass.cls#double_gel_8d_versus_single_gel_8d_repos
Upregulated in classsingle_gel_8d
GeneSetUVC_TTD_ALL_DN
Enrichment Score (ES)-0.45416176
Normalized Enrichment Score (NES)-1.762054
Nominal p-value0.0
FDR q-value0.060475547
FWER p-Value0.983
Table: GSEA Results Summary



Fig 1: Enrichment plot: UVC_TTD_ALL_DN   
Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List

PROBEGENE SYMBOLGENE_TITLERANK IN GENE LISTRANK METRIC SCORERUNNING ESCORE ENRICHMENT
1DPYDDPYD
Entrez,  Source
dihydropyrimidine dehydrogenase1680.5020.0087No
2PPAP2BPPAP2B
Entrez,  Source
phosphatidic acid phosphatase type 2B2050.4670.0259No
3MGLLMGLL
Entrez,  Source
monoglyceride lipase2410.4430.0422No
4GBE1GBE1
Entrez,  Source
glucan (1,4-alpha-), branching enzyme 1 (glycogen branching enzyme, Andersen disease, glycogen storage disease type IV)3680.3550.0478No
5CXCL12CXCL12
Entrez,  Source
chemokine (C-X-C motif) ligand 12 (stromal cell-derived factor 1)4070.3370.0593No
6MSH3MSH3
Entrez,  Source
mutS homolog 3 (E. coli)4440.3230.0703No
7BHLHB2BHLHB2
Entrez,  Source
basic helix-loop-helix domain containing, class B, 25810.2720.0717No
8PRKCAPRKCA
Entrez,  Source
protein kinase C, alpha7360.2300.0698No
9FUT8FUT8
Entrez,  Source
fucosyltransferase 8 (alpha (1,6) fucosyltransferase)7620.2250.0775No
10IFRD1IFRD1
Entrez,  Source
interferon-related developmental regulator 18370.2150.0811No
11PTPN2PTPN2
Entrez,  Source
protein tyrosine phosphatase, non-receptor type 29220.2040.0835No
12IL1RAPIL1RAP
Entrez,  Source
interleukin 1 receptor accessory protein10370.1880.0828No
13STK39STK39
Entrez,  Source
serine threonine kinase 39 (STE20/SPS1 homolog, yeast)11210.1800.0842No
14MBNL1MBNL1
Entrez,  Source
muscleblind-like (Drosophila)13430.1610.0744No
15PRKCBP1PRKCBP1
Entrez,  Source
protein kinase C binding protein 116760.1380.0551No
16FYNFYN
Entrez,  Source
FYN oncogene related to SRC, FGR, YES16910.1370.0599No
17SERPINE1SERPINE1
Entrez,  Source
serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 119380.1250.0466No
18CREBBPCREBBP
Entrez,  Source
CREB binding protein (Rubinstein-Taybi syndrome)21020.1180.0392No
19TMEM23TMEM23
Entrez,  Source
transmembrane protein 2324730.1040.0156No
20IGF2BP3IGF2BP3
Entrez,  Source
insulin-like growth factor 2 mRNA binding protein 325300.1020.0157No
21MYO1BMYO1B
Entrez,  Source
myosin IB25690.1000.0171No
22PEX14PEX14
Entrez,  Source
peroxisomal biogenesis factor 1427220.0950.0096No
23ATRXATRX
Entrez,  Source
alpha thalassemia/mental retardation syndrome X-linked (RAD54 homolog, S. cerevisiae)28460.0900.0041No
24SIPA1L1SIPA1L1
Entrez,  Source
signal-induced proliferation-associated 1 like 128780.0890.0056No
25RGS7RGS7
Entrez,  Source
regulator of G-protein signalling 730110.085-0.0008No
26DLC1DLC1
Entrez,  Source
deleted in liver cancer 130320.0840.0013No
27HOMER1HOMER1
Entrez,  Source
homer homolog 1 (Drosophila)32680.077-0.0133No
28DUSP1DUSP1
Entrez,  Source
dual specificity phosphatase 132750.077-0.0105No
29FLNBFLNB
Entrez,  Source
filamin B, beta (actin binding protein 278)33170.076-0.0103No
30CDC42BPACDC42BPA
Entrez,  Source
CDC42 binding protein kinase alpha (DMPK-like)35120.071-0.0220No
31PTPRMPTPRM
Entrez,  Source
protein tyrosine phosphatase, receptor type, M36190.068-0.0272No
32CEP350CEP350
Entrez,  Source
centrosomal protein 350kDa37150.066-0.0315No
33MYCMYC
Entrez,  Source
v-myc myelocytomatosis viral oncogene homolog (avian)38050.064-0.0356No
34ZHX3ZHX3
Entrez,  Source
zinc fingers and homeoboxes 338740.063-0.0380No
35FGF5FGF5
Entrez,  Source
fibroblast growth factor 539360.061-0.0401No
36FGF2FGF2
Entrez,  Source
fibroblast growth factor 2 (basic)40960.057-0.0497No
37CNOT4CNOT4
Entrez,  Source
CCR4-NOT transcription complex, subunit 442180.055-0.0565No
38SPOPSPOP
Entrez,  Source
speckle-type POZ protein43160.052-0.0616No
39CAP2CAP2
Entrez,  Source
CAP, adenylate cyclase-associated protein, 2 (yeast)44330.050-0.0683No
40ARNT2ARNT2
Entrez,  Source
aryl-hydrocarbon receptor nuclear translocator 247410.043-0.0897No
41EDG2EDG2
Entrez,  Source
endothelial differentiation, lysophosphatidic acid G-protein-coupled receptor, 248940.040-0.0996No
42EIF4EEIF4E
Entrez,  Source
eukaryotic translation initiation factor 4E51860.034-0.1202No
43ORC2LORC2L
Entrez,  Source
origin recognition complex, subunit 2-like (yeast)52730.032-0.1253No
44BARD1BARD1
Entrez,  Source
BRCA1 associated RING domain 152780.032-0.1242No
45ATXN1ATXN1
Entrez,  Source
ataxin 154430.029-0.1354No
46SLIT1SLIT1
Entrez,  Source
slit homolog 1 (Drosophila)57660.023-0.1589No
47LYNLYN
Entrez,  Source
v-yes-1 Yamaguchi sarcoma viral related oncogene homolog58550.021-0.1646No
48ACVR2AACVR2A
Entrez,  Source
activin A receptor, type IIA58630.021-0.1643No
49PTPN12PTPN12
Entrez,  Source
protein tyrosine phosphatase, non-receptor type 1260580.017-0.1783No
50CRY1CRY1
Entrez,  Source
cryptochrome 1 (photolyase-like)63560.010-0.2003No
51FARS2FARS2
Entrez,  Source
phenylalanine-tRNA synthetase 2 (mitochondrial)64200.009-0.2047No
52SYNJ2SYNJ2
Entrez,  Source
synaptojanin 264750.008-0.2084No
53HNRPDLHNRPDL
Entrez,  Source
heterogeneous nuclear ribonucleoprotein D-like65560.007-0.2142No
54UBL3UBL3
Entrez,  Source
ubiquitin-like 365770.006-0.2155No
55SLC4A7SLC4A7
Entrez,  Source
solute carrier family 4, sodium bicarbonate cotransporter, member 766660.005-0.2219No
56VEGFCVEGFC
Entrez,  Source
vascular endothelial growth factor C67270.004-0.2263No
57CUTL1CUTL1
Entrez,  Source
cut-like 1, CCAAT displacement protein (Drosophila)6916-0.000-0.2406No
58ATP2B1ATP2B1
Entrez,  Source
ATPase, Ca++ transporting, plasma membrane 16925-0.000-0.2412No
59MGAT5MGAT5
Entrez,  Source
mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase6976-0.002-0.2449No
60MAPK6MAPK6
Entrez,  Source
mitogen-activated protein kinase 67114-0.004-0.2551No
61GTF2F2GTF2F2
Entrez,  Source
general transcription factor IIF, polypeptide 2, 30kDa7227-0.007-0.2633No
62AFAPAFAP
Entrez,  Source
-7458-0.011-0.2803No
63XRCC4XRCC4
Entrez,  Source
X-ray repair complementing defective repair in Chinese hamster cells 47672-0.016-0.2957No
64PPP1R12APPP1R12A
Entrez,  Source
protein phosphatase 1, regulatory (inhibitor) subunit 12A7740-0.017-0.3001No
65BMP2KBMP2K
Entrez,  Source
BMP2 inducible kinase7875-0.020-0.3094No
66AMPHAMPH
Entrez,  Source
amphiphysin (Stiff-Man syndrome with breast cancer 128kDa autoantigen)8098-0.025-0.3251No
67NIPBLNIPBL
Entrez,  Source
Nipped-B homolog (Drosophila)8250-0.029-0.3353No
68NUP98NUP98
Entrez,  Source
nucleoporin 98kDa8376-0.032-0.3434No
69TDRD3TDRD3
Entrez,  Source
tudor domain containing 38567-0.036-0.3563No
70KLF10KLF10
Entrez,  Source
Kruppel-like factor 108626-0.037-0.3591No
71DYRK1ADYRK1A
Entrez,  Source
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A8768-0.040-0.3681No
72GSK3BGSK3B
Entrez,  Source
glycogen synthase kinase 3 beta8782-0.040-0.3673No
73ZMYND11ZMYND11
Entrez,  Source
zinc finger, MYND domain containing 118813-0.041-0.3679No
74MYST3MYST3
Entrez,  Source
MYST histone acetyltransferase (monocytic leukemia) 38920-0.044-0.3740No
75SKAP2SKAP2
Entrez,  Source
src kinase associated phosphoprotein 29093-0.049-0.3850No
76ARIH1ARIH1
Entrez,  Source
ariadne homolog, ubiquitin-conjugating enzyme E2 binding protein, 1 (Drosophila)9421-0.058-0.4073No
77SERPINB2SERPINB2
Entrez,  Source
serpin peptidase inhibitor, clade B (ovalbumin), member 29455-0.058-0.4073No
78ARHGEF7ARHGEF7
Entrez,  Source
Rho guanine nucleotide exchange factor (GEF) 79623-0.063-0.4173No
79PKN2PKN2
Entrez,  Source
protein kinase N29626-0.063-0.4147No
80GNAQGNAQ
Entrez,  Source
guanine nucleotide binding protein (G protein), q polypeptide9655-0.064-0.4141No
81HAS2HAS2
Entrez,  Source
hyaluronan synthase 29840-0.070-0.4251No
82STRN3STRN3
Entrez,  Source
striatin, calmodulin binding protein 39894-0.071-0.4261No
83RSNRSN
Entrez,  Source
restin (Reed-Steinberg cell-expressed intermediate filament-associated protein)9993-0.074-0.4303No
84NRG1NRG1
Entrez,  Source
neuregulin 110017-0.075-0.4289No
85ZRF1ZRF1
Entrez,  Source
zuotin related factor 110048-0.076-0.4279No
86WDR7WDR7
Entrez,  Source
WD repeat domain 710063-0.077-0.4257No
87ID1ID1
Entrez,  Source
inhibitor of DNA binding 1, dominant negative helix-loop-helix protein10098-0.078-0.4249No
88EGFREGFR
Entrez,  Source
epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian)10171-0.080-0.4269No
89ITSN1ITSN1
Entrez,  Source
intersectin 1 (SH3 domain protein)10184-0.081-0.4244No
90MAP2K4MAP2K4
Entrez,  Source
mitogen-activated protein kinase kinase 410267-0.084-0.4271No
91RBM16RBM16
Entrez,  Source
RNA binding motif protein 1610272-0.084-0.4238No
92NCOA3NCOA3
Entrez,  Source
nuclear receptor coactivator 310363-0.087-0.4269No
93CNOT2CNOT2
Entrez,  Source
CCR4-NOT transcription complex, subunit 210411-0.089-0.4267No
94RBM39RBM39
Entrez,  Source
RNA binding motif protein 3910593-0.095-0.4364No
95GPR176GPR176
Entrez,  Source
G protein-coupled receptor 17610605-0.095-0.4331No
96PHLPPPHLPP
Entrez,  Source
PH domain and leucine rich repeat protein phosphatase10612-0.095-0.4295No
97MDN1MDN1
Entrez,  Source
MDN1, midasin homolog (yeast)10751-0.101-0.4357No
98PAFAH1B1PAFAH1B1
Entrez,  Source
platelet-activating factor acetylhydrolase, isoform Ib, alpha subunit 45kDa10819-0.104-0.4363No
99MNAT1MNAT1
Entrez,  Source
menage a trois homolog 1, cyclin H assembly factor (Xenopus laevis)10832-0.104-0.4328No
100CBLBCBLB
Entrez,  Source
Cas-Br-M (murine) ecotropic retroviral transforming sequence b10938-0.109-0.4361No
101PLEKHC1PLEKHC1
Entrez,  Source
pleckstrin homology domain containing, family C (with FERM domain) member 111076-0.115-0.4416No
102PPP2R2APPP2R2A
Entrez,  Source
protein phosphatase 2 (formerly 2A), regulatory subunit B (PR 52), alpha isoform11243-0.124-0.4489Yes
103CTGFCTGF
Entrez,  Source
connective tissue growth factor11278-0.125-0.4461Yes
104NUP153NUP153
Entrez,  Source
nucleoporin 153kDa11280-0.126-0.4408Yes
105ZNF148ZNF148
Entrez,  Source
zinc finger protein 14811301-0.126-0.4369Yes
106ENC1ENC1
Entrez,  Source
ectodermal-neural cortex (with BTB-like domain)11316-0.127-0.4326Yes
107CASP8CASP8
Entrez,  Source
caspase 8, apoptosis-related cysteine peptidase11401-0.131-0.4333Yes
108STK3STK3
Entrez,  Source
serine/threonine kinase 3 (STE20 homolog, yeast)11428-0.133-0.4297Yes
109TUBGCP3TUBGCP3
Entrez,  Source
tubulin, gamma complex associated protein 311484-0.136-0.4280Yes
110MARCH7MARCH7
Entrez,  Source
membrane-associated ring finger (C3HC4) 711511-0.138-0.4241Yes
111SMAD3SMAD3
Entrez,  Source
SMAD, mothers against DPP homolog 3 (Drosophila)11527-0.139-0.4193Yes
112ATF2ATF2
Entrez,  Source
activating transcription factor 211597-0.143-0.4184Yes
113SEPT9SEPT9
Entrez,  Source
septin 911618-0.145-0.4137Yes
114FUBP1FUBP1
Entrez,  Source
far upstream element (FUSE) binding protein 111776-0.155-0.4190Yes
115PUM2PUM2
Entrez,  Source
pumilio homolog 2 (Drosophila)11991-0.172-0.4279Yes
116ACVR1ACVR1
Entrez,  Source
activin A receptor, type I11998-0.173-0.4210Yes
117PARGPARG
Entrez,  Source
poly (ADP-ribose) glycohydrolase12022-0.175-0.4153Yes
118NFIBNFIB
Entrez,  Source
nuclear factor I/B12064-0.179-0.4107Yes
119TLE4TLE4
Entrez,  Source
transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila)12093-0.181-0.4051Yes
120ABI1ABI1
Entrez,  Source
abl-interactor 112095-0.181-0.3975Yes
121TSPAN5TSPAN5
Entrez,  Source
tetraspanin 512120-0.183-0.3915Yes
122ROCK2ROCK2
Entrez,  Source
Rho-associated, coiled-coil containing protein kinase 212156-0.187-0.3861Yes
123MTMR3MTMR3
Entrez,  Source
myotubularin related protein 312309-0.205-0.3889Yes
124OGTOGT
Entrez,  Source
O-linked N-acetylglucosamine (GlcNAc) transferase (UDP-N-acetylglucosamine:polypeptide-N-acetylglucosaminyl transferase)12392-0.214-0.3860Yes
125PTK2PTK2
Entrez,  Source
PTK2 protein tyrosine kinase 212413-0.216-0.3783Yes
126MID1MID1
Entrez,  Source
midline 1 (Opitz/BBB syndrome)12463-0.223-0.3725Yes
127REV3LREV3L
Entrez,  Source
REV3-like, catalytic subunit of DNA polymerase zeta (yeast)12493-0.227-0.3650Yes
128PRIM2APRIM2A
Entrez,  Source
primase, polypeptide 2A, 58kDa12498-0.229-0.3555Yes
129CLASP2CLASP2
Entrez,  Source
cytoplasmic linker associated protein 212533-0.233-0.3481Yes
130TRIOTRIO
Entrez,  Source
triple functional domain (PTPRF interacting)12599-0.245-0.3426Yes
131CASKCASK
Entrez,  Source
calcium/calmodulin-dependent serine protein kinase (MAGUK family)12614-0.247-0.3331Yes
132KIF2AKIF2A
Entrez,  Source
kinesin heavy chain member 2A12626-0.249-0.3233Yes
133PTPRKPTPRK
Entrez,  Source
protein tyrosine phosphatase, receptor type, K12652-0.254-0.3144Yes
134SPBC25SPBC25
Entrez,  Source
spindle pole body component 25 homolog (S. cerevisiae)12653-0.254-0.3035Yes
135RRAS2RRAS2
Entrez,  Source
related RAS viral (r-ras) oncogene homolog 212665-0.257-0.2934Yes
136MTF2MTF2
Entrez,  Source
metal response element binding transcription factor 212667-0.258-0.2825Yes
137TCF12TCF12
Entrez,  Source
transcription factor 12 (HTF4, helix-loop-helix transcription factors 4)12690-0.262-0.2730Yes
138UGCGUGCG
Entrez,  Source
UDP-glucose ceramide glucosyltransferase12723-0.270-0.2639Yes
139CEP170CEP170
Entrez,  Source
centrosomal protein 170kDa12737-0.273-0.2532Yes
140COL5A2COL5A2
Entrez,  Source
collagen, type V, alpha 212760-0.277-0.2430Yes
141TGFB2TGFB2
Entrez,  Source
transforming growth factor, beta 212832-0.296-0.2358Yes
142PCTK2PCTK2
Entrez,  Source
PCTAIRE protein kinase 212886-0.316-0.2263Yes
143CLASP1CLASP1
Entrez,  Source
cytoplasmic linker associated protein 112909-0.326-0.2141Yes
144SCHIP1SCHIP1
Entrez,  Source
schwannomin interacting protein 112910-0.326-0.2002Yes
145RUNX1RUNX1
Entrez,  Source
runt-related transcription factor 1 (acute myeloid leukemia 1; aml1 oncogene)12949-0.338-0.1886Yes
146ZNF292ZNF292
Entrez,  Source
zinc finger protein 29213045-0.393-0.1791Yes
147GNAI1GNAI1
Entrez,  Source
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 113055-0.401-0.1626Yes
148GULP1GULP1
Entrez,  Source
GULP, engulfment adaptor PTB domain containing 113058-0.404-0.1455Yes
149PARD3PARD3
Entrez,  Source
par-3 partitioning defective 3 homolog (C. elegans)13124-0.445-0.1314Yes
150CCND1CCND1
Entrez,  Source
cyclin D113162-0.500-0.1129Yes
151PDLIM5PDLIM5
Entrez,  Source
PDZ and LIM domain 513173-0.513-0.0918Yes
152CTBP2CTBP2
Entrez,  Source
C-terminal binding protein 213212-0.580-0.0699Yes
153PPP2R3APPP2R3A
Entrez,  Source
protein phosphatase 2 (formerly 2A), regulatory subunit B'', alpha13267-0.745-0.0421Yes
154F3F3
Entrez,  Source
coagulation factor III (thromboplastin, tissue factor)13324-1.1190.0014Yes
Table: GSEA details [plain text format]



Fig 2: UVC_TTD_ALL_DN   
Blue-Pink O' Gram in the Space of the Analyzed GeneSet



Fig 3: UVC_TTD_ALL_DN: Random ES distribution   
Gene set null distribution of ES for UVC_TTD_ALL_DN