Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_single_gel_8d.class.cls #double_gel_8d_versus_single_gel_8d_repos |
| Phenotype | class.cls#double_gel_8d_versus_single_gel_8d_repos |
| Upregulated in class | single_gel_8d |
| GeneSet | V$ARNT_02 |
| Enrichment Score (ES) | -0.48549145 |
| Normalized Enrichment Score (NES) | -1.7816561 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.05370528 |
| FWER p-Value | 0.955 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | TIMM8A | TIMM8A Entrez, Source | translocase of inner mitochondrial membrane 8 homolog A (yeast) | 412 | 0.336 | -0.0096 | No |
| 2 | ALDH6A1 | ALDH6A1 Entrez, Source | aldehyde dehydrogenase 6 family, member A1 | 524 | 0.292 | 0.0008 | No |
| 3 | RAB30 | RAB30 Entrez, Source | RAB30, member RAS oncogene family | 545 | 0.284 | 0.0175 | No |
| 4 | CPT1A | CPT1A Entrez, Source | carnitine palmitoyltransferase 1A (liver) | 950 | 0.200 | -0.0002 | No |
| 5 | GNAS | GNAS Entrez, Source | GNAS complex locus | 968 | 0.198 | 0.0112 | No |
| 6 | MRPL40 | MRPL40 Entrez, Source | mitochondrial ribosomal protein L40 | 981 | 0.197 | 0.0230 | No |
| 7 | GMFB | GMFB Entrez, Source | glia maturation factor, beta | 1544 | 0.146 | -0.0101 | No |
| 8 | CDK5R1 | CDK5R1 Entrez, Source | cyclin-dependent kinase 5, regulatory subunit 1 (p35) | 1630 | 0.141 | -0.0075 | No |
| 9 | FXYD6 | FXYD6 Entrez, Source | FXYD domain containing ion transport regulator 6 | 2165 | 0.116 | -0.0404 | No |
| 10 | DSCAM | DSCAM Entrez, Source | Down syndrome cell adhesion molecule | 2452 | 0.105 | -0.0553 | No |
| 11 | EGLN2 | EGLN2 Entrez, Source | egl nine homolog 2 (C. elegans) | 2499 | 0.103 | -0.0522 | No |
| 12 | ATF4 | ATF4 Entrez, Source | activating transcription factor 4 (tax-responsive enhancer element B67) | 2527 | 0.102 | -0.0477 | No |
| 13 | THUMPD2 | THUMPD2 Entrez, Source | THUMP domain containing 2 | 2667 | 0.097 | -0.0520 | No |
| 14 | GPM6B | GPM6B Entrez, Source | glycoprotein M6B | 2860 | 0.089 | -0.0608 | No |
| 15 | CANX | CANX Entrez, Source | calnexin | 2961 | 0.086 | -0.0628 | No |
| 16 | RAB24 | RAB24 Entrez, Source | RAB24, member RAS oncogene family | 3137 | 0.080 | -0.0708 | No |
| 17 | LTBR | LTBR Entrez, Source | lymphotoxin beta receptor (TNFR superfamily, member 3) | 3340 | 0.075 | -0.0813 | No |
| 18 | FOXD3 | FOXD3 Entrez, Source | forkhead box D3 | 3547 | 0.070 | -0.0924 | No |
| 19 | PRSS15 | PRSS15 Entrez, Source | protease, serine, 15 | 3990 | 0.060 | -0.1220 | No |
| 20 | PRKCE | PRKCE Entrez, Source | protein kinase C, epsilon | 4038 | 0.059 | -0.1218 | No |
| 21 | SLC38A5 | SLC38A5 Entrez, Source | solute carrier family 38, member 5 | 4409 | 0.050 | -0.1465 | No |
| 22 | SLCO1C1 | SLCO1C1 Entrez, Source | solute carrier organic anion transporter family, member 1C1 | 4663 | 0.045 | -0.1627 | No |
| 23 | ELAVL3 | ELAVL3 Entrez, Source | ELAV (embryonic lethal, abnormal vision, Drosophila)-like 3 (Hu antigen C) | 4806 | 0.042 | -0.1708 | No |
| 24 | ZIC1 | ZIC1 Entrez, Source | Zic family member 1 (odd-paired homolog, Drosophila) | 4842 | 0.041 | -0.1708 | No |
| 25 | AVPI1 | AVPI1 Entrez, Source | arginine vasopressin-induced 1 | 4869 | 0.040 | -0.1701 | No |
| 26 | NFX1 | NFX1 Entrez, Source | nuclear transcription factor, X-box binding 1 | 5152 | 0.035 | -0.1892 | No |
| 27 | CD164 | CD164 Entrez, Source | CD164 molecule, sialomucin | 5266 | 0.032 | -0.1957 | No |
| 28 | UBE2B | UBE2B Entrez, Source | ubiquitin-conjugating enzyme E2B (RAD6 homolog) | 5274 | 0.032 | -0.1941 | No |
| 29 | HOXA1 | HOXA1 Entrez, Source | homeobox A1 | 5497 | 0.028 | -0.2091 | No |
| 30 | ATP6V1H | ATP6V1H Entrez, Source | ATPase, H+ transporting, lysosomal 50/57kDa, V1 subunit H | 5583 | 0.026 | -0.2139 | No |
| 31 | SLC36A1 | SLC36A1 Entrez, Source | solute carrier family 36 (proton/amino acid symporter), member 1 | 5594 | 0.026 | -0.2130 | No |
| 32 | VGF | VGF Entrez, Source | VGF nerve growth factor inducible | 5814 | 0.022 | -0.2281 | No |
| 33 | CHRM1 | CHRM1 Entrez, Source | cholinergic receptor, muscarinic 1 | 5978 | 0.019 | -0.2392 | No |
| 34 | SYNCRIP | SYNCRIP Entrez, Source | synaptotagmin binding, cytoplasmic RNA interacting protein | 6146 | 0.015 | -0.2508 | No |
| 35 | TUBA4 | TUBA4 Entrez, Source | tubulin, alpha 4 | 6235 | 0.013 | -0.2566 | No |
| 36 | HRH3 | HRH3 Entrez, Source | histamine receptor H3 | 6371 | 0.010 | -0.2662 | No |
| 37 | NR1D1 | NR1D1 Entrez, Source | nuclear receptor subfamily 1, group D, member 1 | 6399 | 0.010 | -0.2676 | No |
| 38 | CLN3 | CLN3 Entrez, Source | ceroid-lipofuscinosis, neuronal 3, juvenile (Batten, Spielmeyer-Vogt disease) | 6686 | 0.004 | -0.2889 | No |
| 39 | CSK | CSK Entrez, Source | c-src tyrosine kinase | 6873 | 0.001 | -0.3029 | No |
| 40 | SEC23IP | SEC23IP Entrez, Source | SEC23 interacting protein | 7260 | -0.008 | -0.3316 | No |
| 41 | SOCS2 | SOCS2 Entrez, Source | suppressor of cytokine signaling 2 | 7521 | -0.013 | -0.3504 | No |
| 42 | PSME3 | PSME3 Entrez, Source | proteasome (prosome, macropain) activator subunit 3 (PA28 gamma; Ki) | 7867 | -0.020 | -0.3752 | No |
| 43 | HSPBAP1 | HSPBAP1 Entrez, Source | HSPB (heat shock 27kDa) associated protein 1 | 7879 | -0.020 | -0.3747 | No |
| 44 | AKAP1 | AKAP1 Entrez, Source | A kinase (PRKA) anchor protein 1 | 8091 | -0.025 | -0.3891 | No |
| 45 | PIAS4 | PIAS4 Entrez, Source | protein inhibitor of activated STAT, 4 | 8140 | -0.026 | -0.3910 | No |
| 46 | DIRC2 | DIRC2 Entrez, Source | disrupted in renal carcinoma 2 | 8205 | -0.028 | -0.3941 | No |
| 47 | SMNDC1 | SMNDC1 Entrez, Source | survival motor neuron domain containing 1 | 8217 | -0.028 | -0.3931 | No |
| 48 | CDKN2C | CDKN2C Entrez, Source | cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) | 8322 | -0.030 | -0.3990 | No |
| 49 | NEUROD2 | NEUROD2 Entrez, Source | neurogenic differentiation 2 | 8448 | -0.033 | -0.4063 | No |
| 50 | H2AFZ | H2AFZ Entrez, Source | H2A histone family, member Z | 8540 | -0.035 | -0.4109 | No |
| 51 | PA2G4 | PA2G4 Entrez, Source | proliferation-associated 2G4, 38kDa | 8877 | -0.043 | -0.4335 | No |
| 52 | GATA4 | GATA4 Entrez, Source | GATA binding protein 4 | 8964 | -0.045 | -0.4371 | No |
| 53 | GGN | GGN Entrez, Source | gametogenetin | 9072 | -0.048 | -0.4422 | No |
| 54 | LZTS2 | LZTS2 Entrez, Source | leucine zipper, putative tumor suppressor 2 | 9078 | -0.048 | -0.4394 | No |
| 55 | NCL | NCL Entrez, Source | nucleolin | 9096 | -0.049 | -0.4376 | No |
| 56 | TRPM7 | TRPM7 Entrez, Source | transient receptor potential cation channel, subfamily M, member 7 | 9127 | -0.049 | -0.4367 | No |
| 57 | U2AF2 | U2AF2 Entrez, Source | U2 small nuclear RNA auxiliary factor 2 | 9141 | -0.050 | -0.4345 | No |
| 58 | ASNA1 | ASNA1 Entrez, Source | arsA arsenite transporter, ATP-binding, homolog 1 (bacterial) | 9162 | -0.050 | -0.4328 | No |
| 59 | RRAGB | RRAGB Entrez, Source | Ras-related GTP binding B | 9173 | -0.051 | -0.4303 | No |
| 60 | CUL5 | CUL5 Entrez, Source | cullin 5 | 9220 | -0.052 | -0.4304 | No |
| 61 | RPS2 | RPS2 Entrez, Source | ribosomal protein S2 | 9340 | -0.055 | -0.4359 | No |
| 62 | POLR3C | POLR3C Entrez, Source | polymerase (RNA) III (DNA directed) polypeptide C (62kD) | 9462 | -0.059 | -0.4412 | No |
| 63 | ARPC5 | ARPC5 Entrez, Source | actin related protein 2/3 complex, subunit 5, 16kDa | 9496 | -0.060 | -0.4399 | No |
| 64 | ATP7A | ATP7A Entrez, Source | ATPase, Cu++ transporting, alpha polypeptide (Menkes syndrome) | 9722 | -0.066 | -0.4527 | No |
| 65 | PDCD6IP | PDCD6IP Entrez, Source | programmed cell death 6 interacting protein | 9842 | -0.070 | -0.4572 | No |
| 66 | LAMP1 | LAMP1 Entrez, Source | lysosomal-associated membrane protein 1 | 9876 | -0.070 | -0.4552 | No |
| 67 | AATF | AATF Entrez, Source | apoptosis antagonizing transcription factor | 10083 | -0.078 | -0.4658 | No |
| 68 | GNB2 | GNB2 Entrez, Source | guanine nucleotide binding protein (G protein), beta polypeptide 2 | 10152 | -0.080 | -0.4658 | No |
| 69 | TRIM3 | TRIM3 Entrez, Source | tripartite motif-containing 3 | 10182 | -0.081 | -0.4628 | No |
| 70 | EIF4B | EIF4B Entrez, Source | eukaryotic translation initiation factor 4B | 10193 | -0.081 | -0.4584 | No |
| 71 | CLTC | CLTC Entrez, Source | clathrin, heavy chain (Hc) | 10233 | -0.082 | -0.4560 | No |
| 72 | HTATIP | HTATIP Entrez, Source | HIV-1 Tat interacting protein, 60kDa | 10248 | -0.083 | -0.4518 | No |
| 73 | APEX1 | APEX1 Entrez, Source | APEX nuclease (multifunctional DNA repair enzyme) 1 | 10323 | -0.086 | -0.4519 | No |
| 74 | CBARA1 | CBARA1 Entrez, Source | calcium binding atopy-related autoantigen 1 | 10356 | -0.087 | -0.4487 | No |
| 75 | EIF4G1 | EIF4G1 Entrez, Source | eukaryotic translation initiation factor 4 gamma, 1 | 10369 | -0.087 | -0.4440 | No |
| 76 | BRD2 | BRD2 Entrez, Source | bromodomain containing 2 | 10513 | -0.092 | -0.4489 | No |
| 77 | BAX | BAX Entrez, Source | BCL2-associated X protein | 10699 | -0.098 | -0.4566 | No |
| 78 | HEXA | HEXA Entrez, Source | hexosaminidase A (alpha polypeptide) | 10771 | -0.102 | -0.4554 | No |
| 79 | RNF44 | RNF44 Entrez, Source | ring finger protein 44 | 10881 | -0.106 | -0.4569 | No |
| 80 | ATP6V1C1 | ATP6V1C1 Entrez, Source | ATPase, H+ transporting, lysosomal 42kDa, V1 subunit C1 | 11130 | -0.118 | -0.4680 | No |
| 81 | RNF146 | RNF146 Entrez, Source | ring finger protein 146 | 11245 | -0.124 | -0.4687 | No |
| 82 | OSGEP | OSGEP Entrez, Source | O-sialoglycoprotein endopeptidase | 11295 | -0.126 | -0.4643 | No |
| 83 | IGF2R | IGF2R Entrez, Source | insulin-like growth factor 2 receptor | 11315 | -0.127 | -0.4576 | No |
| 84 | SPG21 | SPG21 Entrez, Source | spastic paraplegia 21, maspardin (autosomal recessive, Mast syndrome) | 11641 | -0.146 | -0.4727 | No |
| 85 | HNRPA1 | HNRPA1 Entrez, Source | heterogeneous nuclear ribonucleoprotein A1 | 11811 | -0.158 | -0.4754 | Yes |
| 86 | HIF1A | HIF1A Entrez, Source | hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 11816 | -0.158 | -0.4655 | Yes |
| 87 | PICALM | PICALM Entrez, Source | phosphatidylinositol binding clathrin assembly protein | 11850 | -0.160 | -0.4578 | Yes |
| 88 | VLDLR | VLDLR Entrez, Source | very low density lipoprotein receptor | 12034 | -0.176 | -0.4603 | Yes |
| 89 | PTPRF | PTPRF Entrez, Source | protein tyrosine phosphatase, receptor type, F | 12043 | -0.177 | -0.4496 | Yes |
| 90 | HMGA1 | HMGA1 Entrez, Source | high mobility group AT-hook 1 | 12047 | -0.177 | -0.4384 | Yes |
| 91 | STX6 | STX6 Entrez, Source | syntaxin 6 | 12357 | -0.211 | -0.4482 | Yes |
| 92 | SNX16 | SNX16 Entrez, Source | sorting nexin 16 | 12373 | -0.212 | -0.4358 | Yes |
| 93 | NOTCH1 | NOTCH1 Entrez, Source | Notch homolog 1, translocation-associated (Drosophila) | 12433 | -0.219 | -0.4262 | Yes |
| 94 | FABP3 | FABP3 Entrez, Source | fatty acid binding protein 3, muscle and heart (mammary-derived growth inhibitor) | 12473 | -0.224 | -0.4148 | Yes |
| 95 | DCTN4 | DCTN4 Entrez, Source | dynactin 4 (p62) | 12513 | -0.230 | -0.4029 | Yes |
| 96 | PRDM4 | PRDM4 Entrez, Source | PR domain containing 4 | 12579 | -0.241 | -0.3924 | Yes |
| 97 | FEN1 | FEN1 Entrez, Source | flap structure-specific endonuclease 1 | 12720 | -0.269 | -0.3857 | Yes |
| 98 | ZBTB10 | ZBTB10 Entrez, Source | zinc finger and BTB domain containing 10 | 12857 | -0.306 | -0.3764 | Yes |
| 99 | CBX6 | CBX6 Entrez, Source | chromobox homolog 6 | 12906 | -0.325 | -0.3591 | Yes |
| 100 | PRPS2 | PRPS2 Entrez, Source | phosphoribosyl pyrophosphate synthetase 2 | 12939 | -0.335 | -0.3400 | Yes |
| 101 | SNN | SNN Entrez, Source | stannin | 12996 | -0.362 | -0.3210 | Yes |
| 102 | SGK | SGK Entrez, Source | serum/glucocorticoid regulated kinase | 12997 | -0.362 | -0.2978 | Yes |
| 103 | CAMK2D | CAMK2D Entrez, Source | calcium/calmodulin-dependent protein kinase (CaM kinase) II delta | 13042 | -0.390 | -0.2761 | Yes |
| 104 | NGFRAP1 | NGFRAP1 Entrez, Source | nerve growth factor receptor (TNFRSF16) associated protein 1 | 13127 | -0.447 | -0.2537 | Yes |
| 105 | RAB31 | RAB31 Entrez, Source | RAB31, member RAS oncogene family | 13154 | -0.487 | -0.2245 | Yes |
| 106 | BDNF | BDNF Entrez, Source | brain-derived neurotrophic factor | 13183 | -0.530 | -0.1925 | Yes |
| 107 | BEX1 | BEX1 Entrez, Source | brain expressed, X-linked 1 | 13225 | -0.617 | -0.1560 | Yes |
| 108 | TCEAL1 | TCEAL1 Entrez, Source | transcription elongation factor A (SII)-like 1 | 13276 | -0.778 | -0.1099 | Yes |
| 109 | STMN1 | STMN1 Entrez, Source | stathmin 1/oncoprotein 18 | 13288 | -0.823 | -0.0579 | Yes |
| 110 | BHLHB3 | BHLHB3 Entrez, Source | basic helix-loop-helix domain containing, class B, 3 | 13305 | -0.964 | 0.0028 | Yes |
