Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_single_gel_8d.class.cls #double_gel_8d_versus_single_gel_8d_repos |
| Phenotype | class.cls#double_gel_8d_versus_single_gel_8d_repos |
| Upregulated in class | double_gel_8d |
| GeneSet | V$COUP_01 |
| Enrichment Score (ES) | 0.48108938 |
| Normalized Enrichment Score (NES) | 1.838844 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.0096614985 |
| FWER p-Value | 0.755 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | G0S2 | G0S2 Entrez, Source | G0/G1switch 2 | 6 | 1.218 | 0.0582 | Yes |
| 2 | G6PC | G6PC Entrez, Source | glucose-6-phosphatase, catalytic subunit | 21 | 0.893 | 0.1001 | Yes |
| 3 | LTB | LTB Entrez, Source | lymphotoxin beta (TNF superfamily, member 3) | 31 | 0.836 | 0.1397 | Yes |
| 4 | GJB2 | GJB2 Entrez, Source | gap junction protein, beta 2, 26kDa (connexin 26) | 37 | 0.807 | 0.1782 | Yes |
| 5 | GYS2 | GYS2 Entrez, Source | glycogen synthase 2 (liver) | 52 | 0.748 | 0.2132 | Yes |
| 6 | FABP2 | FABP2 Entrez, Source | fatty acid binding protein 2, intestinal | 71 | 0.690 | 0.2450 | Yes |
| 7 | ASGR2 | ASGR2 Entrez, Source | asialoglycoprotein receptor 2 | 92 | 0.627 | 0.2737 | Yes |
| 8 | SERPIND1 | SERPIND1 Entrez, Source | serpin peptidase inhibitor, clade D (heparin cofactor), member 1 | 144 | 0.544 | 0.2960 | Yes |
| 9 | APOM | APOM Entrez, Source | apolipoprotein M | 156 | 0.527 | 0.3206 | Yes |
| 10 | PKLR | PKLR Entrez, Source | pyruvate kinase, liver and RBC | 184 | 0.487 | 0.3420 | Yes |
| 11 | PON1 | PON1 Entrez, Source | paraoxonase 1 | 193 | 0.481 | 0.3646 | Yes |
| 12 | HPN | HPN Entrez, Source | hepsin (transmembrane protease, serine 1) | 198 | 0.478 | 0.3873 | Yes |
| 13 | ADRB2 | ADRB2 Entrez, Source | adrenergic, beta-2-, receptor, surface | 298 | 0.399 | 0.3990 | Yes |
| 14 | FKBP5 | FKBP5 Entrez, Source | FK506 binding protein 5 | 405 | 0.337 | 0.4072 | Yes |
| 15 | FOXA3 | FOXA3 Entrez, Source | forkhead box A3 | 492 | 0.303 | 0.4153 | Yes |
| 16 | SERPINC1 | SERPINC1 Entrez, Source | serpin peptidase inhibitor, clade C (antithrombin), member 1 | 522 | 0.293 | 0.4272 | Yes |
| 17 | ALDH6A1 | ALDH6A1 Entrez, Source | aldehyde dehydrogenase 6 family, member A1 | 524 | 0.292 | 0.4412 | Yes |
| 18 | SLC11A2 | SLC11A2 Entrez, Source | solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2 | 538 | 0.287 | 0.4541 | Yes |
| 19 | KYNU | KYNU Entrez, Source | kynureninase (L-kynurenine hydrolase) | 548 | 0.283 | 0.4670 | Yes |
| 20 | VEGF | VEGF Entrez, Source | vascular endothelial growth factor | 585 | 0.271 | 0.4773 | Yes |
| 21 | CREB3L3 | CREB3L3 Entrez, Source | cAMP responsive element binding protein 3-like 3 | 690 | 0.241 | 0.4811 | Yes |
| 22 | MYBPH | MYBPH Entrez, Source | myosin binding protein H | 919 | 0.204 | 0.4737 | No |
| 23 | DOCK11 | DOCK11 Entrez, Source | dedicator of cytokinesis 11 | 1214 | 0.169 | 0.4596 | No |
| 24 | RNF103 | RNF103 Entrez, Source | ring finger protein 103 | 1241 | 0.168 | 0.4657 | No |
| 25 | FGF12 | FGF12 Entrez, Source | fibroblast growth factor 12 | 1563 | 0.145 | 0.4484 | No |
| 26 | PITX2 | PITX2 Entrez, Source | paired-like homeodomain transcription factor 2 | 1599 | 0.143 | 0.4527 | No |
| 27 | STOML2 | STOML2 Entrez, Source | stomatin (EPB72)-like 2 | 1652 | 0.140 | 0.4555 | No |
| 28 | PPARGC1A | PPARGC1A Entrez, Source | peroxisome proliferative activated receptor, gamma, coactivator 1, alpha | 1770 | 0.133 | 0.4530 | No |
| 29 | SLC9A3 | SLC9A3 Entrez, Source | solute carrier family 9 (sodium/hydrogen exchanger), member 3 | 1812 | 0.130 | 0.4562 | No |
| 30 | TCF1 | TCF1 Entrez, Source | transcription factor 1, hepatic; LF-B1, hepatic nuclear factor (HNF1), albumin proximal factor | 1988 | 0.122 | 0.4488 | No |
| 31 | LMO3 | LMO3 Entrez, Source | LIM domain only 3 (rhombotin-like 2) | 1995 | 0.122 | 0.4542 | No |
| 32 | DMD | DMD Entrez, Source | dystrophin (muscular dystrophy, Duchenne and Becker types) | 2146 | 0.116 | 0.4485 | No |
| 33 | ANGPT1 | ANGPT1 Entrez, Source | angiopoietin 1 | 2387 | 0.107 | 0.4355 | No |
| 34 | ZPBP2 | ZPBP2 Entrez, Source | zona pellucida binding protein 2 | 2397 | 0.107 | 0.4400 | No |
| 35 | ATF4 | ATF4 Entrez, Source | activating transcription factor 4 (tax-responsive enhancer element B67) | 2527 | 0.102 | 0.4351 | No |
| 36 | TOMM70A | TOMM70A Entrez, Source | translocase of outer mitochondrial membrane 70 homolog A (S. cerevisiae) | 3062 | 0.083 | 0.3988 | No |
| 37 | ESRRG | ESRRG Entrez, Source | estrogen-related receptor gamma | 3222 | 0.078 | 0.3905 | No |
| 38 | DAB2IP | DAB2IP Entrez, Source | DAB2 interacting protein | 3243 | 0.077 | 0.3927 | No |
| 39 | HSD17B8 | HSD17B8 Entrez, Source | hydroxysteroid (17-beta) dehydrogenase 8 | 3280 | 0.077 | 0.3937 | No |
| 40 | SHC1 | SHC1 Entrez, Source | SHC (Src homology 2 domain containing) transforming protein 1 | 3311 | 0.076 | 0.3950 | No |
| 41 | OTP | OTP Entrez, Source | orthopedia homolog (Drosophila) | 3511 | 0.071 | 0.3834 | No |
| 42 | CRYGC | CRYGC Entrez, Source | crystallin, gamma C | 3590 | 0.069 | 0.3808 | No |
| 43 | SMOC1 | SMOC1 Entrez, Source | SPARC related modular calcium binding 1 | 3671 | 0.067 | 0.3780 | No |
| 44 | PDE3B | PDE3B Entrez, Source | phosphodiesterase 3B, cGMP-inhibited | 3773 | 0.065 | 0.3735 | No |
| 45 | SLC7A7 | SLC7A7 Entrez, Source | solute carrier family 7 (cationic amino acid transporter, y+ system), member 7 | 3774 | 0.065 | 0.3766 | No |
| 46 | LZIC | LZIC Entrez, Source | leucine zipper and CTNNBIP1 domain containing | 4399 | 0.050 | 0.3319 | No |
| 47 | CREB3L2 | CREB3L2 Entrez, Source | cAMP responsive element binding protein 3-like 2 | 4457 | 0.049 | 0.3299 | No |
| 48 | TBX5 | TBX5 Entrez, Source | T-box 5 | 5116 | 0.036 | 0.2819 | No |
| 49 | ARFGEF2 | ARFGEF2 Entrez, Source | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | 5306 | 0.032 | 0.2691 | No |
| 50 | NEK6 | NEK6 Entrez, Source | NIMA (never in mitosis gene a)-related kinase 6 | 5393 | 0.030 | 0.2641 | No |
| 51 | NDUFS1 | NDUFS1 Entrez, Source | NADH dehydrogenase (ubiquinone) Fe-S protein 1, 75kDa (NADH-coenzyme Q reductase) | 5395 | 0.030 | 0.2655 | No |
| 52 | TNNI1 | TNNI1 Entrez, Source | troponin I type 1 (skeletal, slow) | 5503 | 0.028 | 0.2587 | No |
| 53 | NR4A3 | NR4A3 Entrez, Source | nuclear receptor subfamily 4, group A, member 3 | 5891 | 0.020 | 0.2304 | No |
| 54 | WBP4 | WBP4 Entrez, Source | WW domain binding protein 4 (formin binding protein 21) | 6097 | 0.016 | 0.2157 | No |
| 55 | DNMT3A | DNMT3A Entrez, Source | DNA (cytosine-5-)-methyltransferase 3 alpha | 6724 | 0.004 | 0.1686 | No |
| 56 | LGI4 | LGI4 Entrez, Source | leucine-rich repeat LGI family, member 4 | 6793 | 0.002 | 0.1636 | No |
| 57 | SLC7A9 | SLC7A9 Entrez, Source | solute carrier family 7 (cationic amino acid transporter, y+ system), member 9 | 7015 | -0.002 | 0.1470 | No |
| 58 | NET1 | NET1 Entrez, Source | neuroepithelial cell transforming gene 1 | 7106 | -0.004 | 0.1404 | No |
| 59 | NR2F1 | NR2F1 Entrez, Source | nuclear receptor subfamily 2, group F, member 1 | 7183 | -0.006 | 0.1349 | No |
| 60 | MLLT10 | MLLT10 Entrez, Source | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 | 7276 | -0.008 | 0.1283 | No |
| 61 | GBL | GBL Entrez, Source | - | 7286 | -0.008 | 0.1280 | No |
| 62 | MRPL2 | MRPL2 Entrez, Source | mitochondrial ribosomal protein L2 | 7336 | -0.009 | 0.1248 | No |
| 63 | EFNB1 | EFNB1 Entrez, Source | ephrin-B1 | 7378 | -0.010 | 0.1221 | No |
| 64 | DNAJA2 | DNAJA2 Entrez, Source | DnaJ (Hsp40) homolog, subfamily A, member 2 | 7402 | -0.010 | 0.1209 | No |
| 65 | PTHR1 | PTHR1 Entrez, Source | parathyroid hormone receptor 1 | 7539 | -0.013 | 0.1112 | No |
| 66 | PABPN1 | PABPN1 Entrez, Source | poly(A) binding protein, nuclear 1 | 7634 | -0.015 | 0.1049 | No |
| 67 | RBBP6 | RBBP6 Entrez, Source | retinoblastoma binding protein 6 | 7722 | -0.017 | 0.0991 | No |
| 68 | TNFRSF12A | TNFRSF12A Entrez, Source | tumor necrosis factor receptor superfamily, member 12A | 7849 | -0.020 | 0.0905 | No |
| 69 | AP1B1 | AP1B1 Entrez, Source | adaptor-related protein complex 1, beta 1 subunit | 7977 | -0.023 | 0.0820 | No |
| 70 | LGALS4 | LGALS4 Entrez, Source | lectin, galactoside-binding, soluble, 4 (galectin 4) | 8066 | -0.025 | 0.0766 | No |
| 71 | NCDN | NCDN Entrez, Source | neurochondrin | 8196 | -0.027 | 0.0682 | No |
| 72 | RBP2 | RBP2 Entrez, Source | retinol binding protein 2, cellular | 8455 | -0.033 | 0.0503 | No |
| 73 | PRKCD | PRKCD Entrez, Source | protein kinase C, delta | 8690 | -0.039 | 0.0344 | No |
| 74 | MAP3K11 | MAP3K11 Entrez, Source | mitogen-activated protein kinase kinase kinase 11 | 8842 | -0.042 | 0.0250 | No |
| 75 | GATA4 | GATA4 Entrez, Source | GATA binding protein 4 | 8964 | -0.045 | 0.0181 | No |
| 76 | TPCN1 | TPCN1 Entrez, Source | two pore segment channel 1 | 9155 | -0.050 | 0.0061 | No |
| 77 | AGPS | AGPS Entrez, Source | alkylglycerone phosphate synthase | 9442 | -0.058 | -0.0127 | No |
| 78 | SYMPK | SYMPK Entrez, Source | symplekin | 9466 | -0.059 | -0.0116 | No |
| 79 | PGF | PGF Entrez, Source | placental growth factor, vascular endothelial growth factor-related protein | 9515 | -0.060 | -0.0124 | No |
| 80 | RQCD1 | RQCD1 Entrez, Source | RCD1 required for cell differentiation1 homolog (S. pombe) | 9601 | -0.063 | -0.0158 | No |
| 81 | ARHGEF7 | ARHGEF7 Entrez, Source | Rho guanine nucleotide exchange factor (GEF) 7 | 9623 | -0.063 | -0.0143 | No |
| 82 | ALDOA | ALDOA Entrez, Source | aldolase A, fructose-bisphosphate | 9745 | -0.066 | -0.0203 | No |
| 83 | NR2F2 | NR2F2 Entrez, Source | nuclear receptor subfamily 2, group F, member 2 | 10001 | -0.075 | -0.0359 | No |
| 84 | PAX6 | PAX6 Entrez, Source | paired box gene 6 (aniridia, keratitis) | 10052 | -0.076 | -0.0360 | No |
| 85 | ID1 | ID1 Entrez, Source | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein | 10098 | -0.078 | -0.0357 | No |
| 86 | EXOSC7 | EXOSC7 Entrez, Source | exosome component 7 | 10123 | -0.079 | -0.0337 | No |
| 87 | RBMS1 | RBMS1 Entrez, Source | RNA binding motif, single stranded interacting protein 1 | 10149 | -0.080 | -0.0317 | No |
| 88 | ADRA1A | ADRA1A Entrez, Source | adrenergic, alpha-1A-, receptor | 10237 | -0.083 | -0.0343 | No |
| 89 | PTMS | PTMS Entrez, Source | parathymosin | 10355 | -0.087 | -0.0390 | No |
| 90 | DLX5 | DLX5 Entrez, Source | distal-less homeobox 5 | 10521 | -0.092 | -0.0471 | No |
| 91 | CRABP2 | CRABP2 Entrez, Source | cellular retinoic acid binding protein 2 | 10545 | -0.093 | -0.0443 | No |
| 92 | PLEC1 | PLEC1 Entrez, Source | plectin 1, intermediate filament binding protein 500kDa | 10694 | -0.098 | -0.0508 | No |
| 93 | MXI1 | MXI1 Entrez, Source | MAX interactor 1 | 10722 | -0.099 | -0.0480 | No |
| 94 | BMF | BMF Entrez, Source | Bcl2 modifying factor | 10943 | -0.109 | -0.0594 | No |
| 95 | PCTK1 | PCTK1 Entrez, Source | PCTAIRE protein kinase 1 | 11022 | -0.113 | -0.0599 | No |
| 96 | MARK2 | MARK2 Entrez, Source | MAP/microtubule affinity-regulating kinase 2 | 11045 | -0.114 | -0.0560 | No |
| 97 | DCTN1 | DCTN1 Entrez, Source | dynactin 1 (p150, glued homolog, Drosophila) | 11343 | -0.128 | -0.0723 | No |
| 98 | SLC26A3 | SLC26A3 Entrez, Source | solute carrier family 26, member 3 | 11528 | -0.139 | -0.0795 | No |
| 99 | RTN2 | RTN2 Entrez, Source | reticulon 2 | 11643 | -0.146 | -0.0811 | No |
| 100 | POLD1 | POLD1 Entrez, Source | polymerase (DNA directed), delta 1, catalytic subunit 125kDa | 11672 | -0.148 | -0.0761 | No |
| 101 | TP53 | TP53 Entrez, Source | tumor protein p53 (Li-Fraumeni syndrome) | 11690 | -0.149 | -0.0702 | No |
| 102 | ZDHHC3 | ZDHHC3 Entrez, Source | zinc finger, DHHC-type containing 3 | 11867 | -0.162 | -0.0757 | No |
| 103 | DDB1 | DDB1 Entrez, Source | damage-specific DNA binding protein 1, 127kDa | 11887 | -0.163 | -0.0693 | No |
| 104 | FOXA1 | FOXA1 Entrez, Source | forkhead box A1 | 11900 | -0.165 | -0.0622 | No |
| 105 | PPP2R5D | PPP2R5D Entrez, Source | protein phosphatase 2, regulatory subunit B (B56), delta isoform | 12011 | -0.174 | -0.0622 | No |
| 106 | DHRS3 | DHRS3 Entrez, Source | dehydrogenase/reductase (SDR family) member 3 | 12291 | -0.203 | -0.0735 | No |
| 107 | LMNA | LMNA Entrez, Source | lamin A/C | 12337 | -0.209 | -0.0668 | No |
| 108 | NRP1 | NRP1 Entrez, Source | neuropilin 1 | 12499 | -0.229 | -0.0680 | No |
| 109 | PRKRA | PRKRA Entrez, Source | protein kinase, interferon-inducible double stranded RNA dependent activator | 12555 | -0.237 | -0.0607 | No |
| 110 | TIMELESS | TIMELESS Entrez, Source | timeless homolog (Drosophila) | 12644 | -0.253 | -0.0552 | No |
| 111 | SATB1 | SATB1 Entrez, Source | special AT-rich sequence binding protein 1 (binds to nuclear matrix/scaffold-associating DNA's) | 12659 | -0.255 | -0.0440 | No |
| 112 | JMJD1C | JMJD1C Entrez, Source | jumonji domain containing 1C | 12770 | -0.278 | -0.0389 | No |
| 113 | FGFR3 | FGFR3 Entrez, Source | fibroblast growth factor receptor 3 (achondroplasia, thanatophoric dwarfism) | 13098 | -0.424 | -0.0432 | No |
| 114 | TCF2 | TCF2 Entrez, Source | transcription factor 2, hepatic; LF-B3; variant hepatic nuclear factor | 13184 | -0.532 | -0.0240 | No |
| 115 | PPP2R3A | PPP2R3A Entrez, Source | protein phosphatase 2 (formerly 2A), regulatory subunit B'', alpha | 13267 | -0.745 | 0.0057 | No |
