Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_single_gel_8d.class.cls #double_gel_8d_versus_single_gel_8d_repos |
| Phenotype | class.cls#double_gel_8d_versus_single_gel_8d_repos |
| Upregulated in class | single_gel_8d |
| GeneSet | V$CP2_02 |
| Enrichment Score (ES) | -0.48032117 |
| Normalized Enrichment Score (NES) | -1.7297797 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.068113506 |
| FWER p-Value | 0.999 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | JUNB | JUNB Entrez, Source | jun B proto-oncogene | 470 | 0.312 | -0.0132 | No |
| 2 | RAB30 | RAB30 Entrez, Source | RAB30, member RAS oncogene family | 545 | 0.284 | 0.0014 | No |
| 3 | DDIT4 | DDIT4 Entrez, Source | DNA-damage-inducible transcript 4 | 720 | 0.235 | 0.0050 | No |
| 4 | ZFHX1B | ZFHX1B Entrez, Source | zinc finger homeobox 1b | 883 | 0.209 | 0.0077 | No |
| 5 | ODC1 | ODC1 Entrez, Source | ornithine decarboxylase 1 | 1205 | 0.170 | -0.0045 | No |
| 6 | SCAMP5 | SCAMP5 Entrez, Source | secretory carrier membrane protein 5 | 1270 | 0.166 | 0.0025 | No |
| 7 | GPC3 | GPC3 Entrez, Source | glypican 3 | 1359 | 0.160 | 0.0073 | No |
| 8 | CNTN6 | CNTN6 Entrez, Source | contactin 6 | 1423 | 0.155 | 0.0136 | No |
| 9 | RHBDF1 | RHBDF1 Entrez, Source | rhomboid 5 homolog 1 (Drosophila) | 1507 | 0.149 | 0.0179 | No |
| 10 | PITX2 | PITX2 Entrez, Source | paired-like homeodomain transcription factor 2 | 1599 | 0.143 | 0.0213 | No |
| 11 | TRPV2 | TRPV2 Entrez, Source | transient receptor potential cation channel, subfamily V, member 2 | 1604 | 0.143 | 0.0311 | No |
| 12 | TNNC1 | TNNC1 Entrez, Source | troponin C type 1 (slow) | 1752 | 0.134 | 0.0296 | No |
| 13 | NTRK3 | NTRK3 Entrez, Source | neurotrophic tyrosine kinase, receptor, type 3 | 1841 | 0.129 | 0.0321 | No |
| 14 | BMP4 | BMP4 Entrez, Source | bone morphogenetic protein 4 | 2116 | 0.117 | 0.0198 | No |
| 15 | ARHGAP5 | ARHGAP5 Entrez, Source | Rho GTPase activating protein 5 | 2435 | 0.105 | 0.0033 | No |
| 16 | DSCAM | DSCAM Entrez, Source | Down syndrome cell adhesion molecule | 2452 | 0.105 | 0.0095 | No |
| 17 | EPN3 | EPN3 Entrez, Source | epsin 3 | 3078 | 0.082 | -0.0318 | No |
| 18 | RGS8 | RGS8 Entrez, Source | regulator of G-protein signalling 8 | 3133 | 0.081 | -0.0302 | No |
| 19 | FGF9 | FGF9 Entrez, Source | fibroblast growth factor 9 (glia-activating factor) | 3279 | 0.077 | -0.0357 | No |
| 20 | CREB1 | CREB1 Entrez, Source | cAMP responsive element binding protein 1 | 3915 | 0.062 | -0.0792 | No |
| 21 | LHX2 | LHX2 Entrez, Source | LIM homeobox 2 | 4202 | 0.055 | -0.0969 | No |
| 22 | AQP6 | AQP6 Entrez, Source | aquaporin 6, kidney specific | 4426 | 0.050 | -0.1101 | No |
| 23 | KLHDC3 | KLHDC3 Entrez, Source | kelch domain containing 3 | 4632 | 0.046 | -0.1224 | No |
| 24 | FEV | FEV Entrez, Source | FEV (ETS oncogene family) | 4641 | 0.045 | -0.1197 | No |
| 25 | FLI1 | FLI1 Entrez, Source | Friend leukemia virus integration 1 | 4742 | 0.043 | -0.1242 | No |
| 26 | DCX | DCX Entrez, Source | doublecortex; lissencephaly, X-linked (doublecortin) | 5004 | 0.038 | -0.1412 | No |
| 27 | DHH | DHH Entrez, Source | desert hedgehog homolog (Drosophila) | 5176 | 0.035 | -0.1517 | No |
| 28 | PTHLH | PTHLH Entrez, Source | parathyroid hormone-like hormone | 5428 | 0.029 | -0.1685 | No |
| 29 | RYR1 | RYR1 Entrez, Source | ryanodine receptor 1 (skeletal) | 5571 | 0.026 | -0.1774 | No |
| 30 | MAPRE3 | MAPRE3 Entrez, Source | microtubule-associated protein, RP/EB family, member 3 | 5635 | 0.025 | -0.1804 | No |
| 31 | NFATC4 | NFATC4 Entrez, Source | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4 | 5709 | 0.024 | -0.1842 | No |
| 32 | DSC2 | DSC2 Entrez, Source | desmocollin 2 | 5772 | 0.022 | -0.1873 | No |
| 33 | LYN | LYN Entrez, Source | v-yes-1 Yamaguchi sarcoma viral related oncogene homolog | 5855 | 0.021 | -0.1920 | No |
| 34 | PRKACA | PRKACA Entrez, Source | protein kinase, cAMP-dependent, catalytic, alpha | 6080 | 0.017 | -0.2077 | No |
| 35 | NR1D1 | NR1D1 Entrez, Source | nuclear receptor subfamily 1, group D, member 1 | 6399 | 0.010 | -0.2310 | No |
| 36 | PRKAG1 | PRKAG1 Entrez, Source | protein kinase, AMP-activated, gamma 1 non-catalytic subunit | 6702 | 0.004 | -0.2536 | No |
| 37 | XPNPEP1 | XPNPEP1 Entrez, Source | X-prolyl aminopeptidase (aminopeptidase P) 1, soluble | 7044 | -0.003 | -0.2791 | No |
| 38 | CAPN6 | CAPN6 Entrez, Source | calpain 6 | 7052 | -0.003 | -0.2794 | No |
| 39 | RPL41 | RPL41 Entrez, Source | ribosomal protein L41 | 7088 | -0.004 | -0.2818 | No |
| 40 | GABARAP | GABARAP Entrez, Source | GABA(A) receptor-associated protein | 7091 | -0.004 | -0.2816 | No |
| 41 | GNB3 | GNB3 Entrez, Source | guanine nucleotide binding protein (G protein), beta polypeptide 3 | 7169 | -0.006 | -0.2871 | No |
| 42 | NR2F1 | NR2F1 Entrez, Source | nuclear receptor subfamily 2, group F, member 1 | 7183 | -0.006 | -0.2876 | No |
| 43 | NRXN3 | NRXN3 Entrez, Source | neurexin 3 | 7351 | -0.009 | -0.2996 | No |
| 44 | KCNH2 | KCNH2 Entrez, Source | potassium voltage-gated channel, subfamily H (eag-related), member 2 | 7491 | -0.012 | -0.3092 | No |
| 45 | CS | CS Entrez, Source | citrate synthase | 7513 | -0.013 | -0.3099 | No |
| 46 | RBBP6 | RBBP6 Entrez, Source | retinoblastoma binding protein 6 | 7722 | -0.017 | -0.3244 | No |
| 47 | KCNC2 | KCNC2 Entrez, Source | potassium voltage-gated channel, Shaw-related subfamily, member 2 | 7729 | -0.017 | -0.3236 | No |
| 48 | PRKCH | PRKCH Entrez, Source | protein kinase C, eta | 7749 | -0.018 | -0.3238 | No |
| 49 | FLOT2 | FLOT2 Entrez, Source | flotillin 2 | 7781 | -0.018 | -0.3248 | No |
| 50 | EFNA3 | EFNA3 Entrez, Source | ephrin-A3 | 7906 | -0.021 | -0.3327 | No |
| 51 | CITED1 | CITED1 Entrez, Source | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 1 | 8046 | -0.024 | -0.3414 | No |
| 52 | HPCAL1 | HPCAL1 Entrez, Source | hippocalcin-like 1 | 8231 | -0.028 | -0.3533 | No |
| 53 | CAMK2G | CAMK2G Entrez, Source | calcium/calmodulin-dependent protein kinase (CaM kinase) II gamma | 8781 | -0.040 | -0.3919 | No |
| 54 | GSK3B | GSK3B Entrez, Source | glycogen synthase kinase 3 beta | 8782 | -0.040 | -0.3890 | No |
| 55 | KCNE3 | KCNE3 Entrez, Source | potassium voltage-gated channel, Isk-related family, member 3 | 9024 | -0.046 | -0.4039 | No |
| 56 | LZTS2 | LZTS2 Entrez, Source | leucine zipper, putative tumor suppressor 2 | 9078 | -0.048 | -0.4045 | No |
| 57 | CRK | CRK Entrez, Source | v-crk sarcoma virus CT10 oncogene homolog (avian) | 9176 | -0.051 | -0.4082 | No |
| 58 | GNAQ | GNAQ Entrez, Source | guanine nucleotide binding protein (G protein), q polypeptide | 9655 | -0.064 | -0.4397 | No |
| 59 | PPP1R9B | PPP1R9B Entrez, Source | protein phosphatase 1, regulatory subunit 9B, spinophilin | 9861 | -0.070 | -0.4502 | No |
| 60 | MDK | MDK Entrez, Source | midkine (neurite growth-promoting factor 2) | 9992 | -0.074 | -0.4547 | No |
| 61 | MAPK3 | MAPK3 Entrez, Source | mitogen-activated protein kinase 3 | 10053 | -0.076 | -0.4538 | No |
| 62 | ADRA1A | ADRA1A Entrez, Source | adrenergic, alpha-1A-, receptor | 10237 | -0.083 | -0.4617 | No |
| 63 | HTATIP | HTATIP Entrez, Source | HIV-1 Tat interacting protein, 60kDa | 10248 | -0.083 | -0.4566 | No |
| 64 | H3F3B | H3F3B Entrez, Source | H3 histone, family 3B (H3.3B) | 10288 | -0.084 | -0.4535 | No |
| 65 | SLC9A1 | SLC9A1 Entrez, Source | solute carrier family 9 (sodium/hydrogen exchanger), member 1 (antiporter, Na+/H+, amiloride sensitive) | 10314 | -0.085 | -0.4493 | No |
| 66 | MORF4L2 | MORF4L2 Entrez, Source | mortality factor 4 like 2 | 10413 | -0.089 | -0.4504 | No |
| 67 | GRB7 | GRB7 Entrez, Source | growth factor receptor-bound protein 7 | 10441 | -0.090 | -0.4461 | No |
| 68 | RASSF1 | RASSF1 Entrez, Source | Ras association (RalGDS/AF-6) domain family 1 | 10613 | -0.096 | -0.4522 | No |
| 69 | YWHAG | YWHAG Entrez, Source | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide | 10619 | -0.096 | -0.4457 | No |
| 70 | KIF5A | KIF5A Entrez, Source | kinesin family member 5A | 10741 | -0.100 | -0.4477 | No |
| 71 | RAB10 | RAB10 Entrez, Source | RAB10, member RAS oncogene family | 10979 | -0.110 | -0.4578 | No |
| 72 | C1QTNF5 | C1QTNF5 Entrez, Source | C1q and tumor necrosis factor related protein 5 | 11078 | -0.115 | -0.4570 | No |
| 73 | TLN1 | TLN1 Entrez, Source | talin 1 | 11127 | -0.118 | -0.4522 | No |
| 74 | TGFBR2 | TGFBR2 Entrez, Source | transforming growth factor, beta receptor II (70/80kDa) | 11501 | -0.137 | -0.4705 | Yes |
| 75 | CHD4 | CHD4 Entrez, Source | chromodomain helicase DNA binding protein 4 | 11593 | -0.143 | -0.4672 | Yes |
| 76 | CALD1 | CALD1 Entrez, Source | caldesmon 1 | 11630 | -0.145 | -0.4596 | Yes |
| 77 | BTBD14B | BTBD14B Entrez, Source | BTB (POZ) domain containing 14B | 11782 | -0.155 | -0.4599 | Yes |
| 78 | HIF1A | HIF1A Entrez, Source | hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 11816 | -0.158 | -0.4512 | Yes |
| 79 | FOXA1 | FOXA1 Entrez, Source | forkhead box A1 | 11900 | -0.165 | -0.4457 | Yes |
| 80 | ALDH3B1 | ALDH3B1 Entrez, Source | aldehyde dehydrogenase 3 family, member B1 | 12169 | -0.189 | -0.4525 | Yes |
| 81 | ADNP | ADNP Entrez, Source | activity-dependent neuroprotector | 12210 | -0.193 | -0.4418 | Yes |
| 82 | CAP1 | CAP1 Entrez, Source | CAP, adenylate cyclase-associated protein 1 (yeast) | 12522 | -0.231 | -0.4488 | Yes |
| 83 | PRDM4 | PRDM4 Entrez, Source | PR domain containing 4 | 12579 | -0.241 | -0.4359 | Yes |
| 84 | GPRC5C | GPRC5C Entrez, Source | G protein-coupled receptor, family C, group 5, member C | 12680 | -0.260 | -0.4249 | Yes |
| 85 | NISCH | NISCH Entrez, Source | nischarin | 12686 | -0.261 | -0.4066 | Yes |
| 86 | DUSP6 | DUSP6 Entrez, Source | dual specificity phosphatase 6 | 12692 | -0.262 | -0.3884 | Yes |
| 87 | NNAT | NNAT Entrez, Source | neuronatin | 13037 | -0.385 | -0.3869 | Yes |
| 88 | DDR1 | DDR1 Entrez, Source | discoidin domain receptor family, member 1 | 13111 | -0.436 | -0.3614 | Yes |
| 89 | NGFRAP1 | NGFRAP1 Entrez, Source | nerve growth factor receptor (TNFRSF16) associated protein 1 | 13127 | -0.447 | -0.3307 | Yes |
| 90 | RTN1 | RTN1 Entrez, Source | reticulon 1 | 13181 | -0.527 | -0.2972 | Yes |
| 91 | BDNF | BDNF Entrez, Source | brain-derived neurotrophic factor | 13183 | -0.530 | -0.2595 | Yes |
| 92 | ACTN1 | ACTN1 Entrez, Source | actinin, alpha 1 | 13226 | -0.619 | -0.2186 | Yes |
| 93 | DDAH2 | DDAH2 Entrez, Source | dimethylarginine dimethylaminohydrolase 2 | 13266 | -0.741 | -0.1688 | Yes |
| 94 | MMP11 | MMP11 Entrez, Source | matrix metallopeptidase 11 (stromelysin 3) | 13273 | -0.768 | -0.1146 | Yes |
| 95 | LTBP1 | LTBP1 Entrez, Source | latent transforming growth factor beta binding protein 1 | 13278 | -0.786 | -0.0590 | Yes |
| 96 | CLDN4 | CLDN4 Entrez, Source | claudin 4 | 13296 | -0.895 | 0.0035 | Yes |
