Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_single_gel_8d.class.cls #double_gel_8d_versus_single_gel_8d_repos |
| Phenotype | class.cls#double_gel_8d_versus_single_gel_8d_repos |
| Upregulated in class | single_gel_8d |
| GeneSet | V$E2F1DP1RB_01 |
| Enrichment Score (ES) | -0.47312316 |
| Normalized Enrichment Score (NES) | -1.7078446 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.07461111 |
| FWER p-Value | 1.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | ATF5 | ATF5 Entrez, Source | activating transcription factor 5 | 511 | 0.296 | -0.0146 | No |
| 2 | ALDH6A1 | ALDH6A1 Entrez, Source | aldehyde dehydrogenase 6 family, member A1 | 524 | 0.292 | 0.0081 | No |
| 3 | AK2 | AK2 Entrez, Source | adenylate kinase 2 | 880 | 0.210 | -0.0017 | No |
| 4 | NELL2 | NELL2 Entrez, Source | NEL-like 2 (chicken) | 1138 | 0.178 | -0.0068 | No |
| 5 | SEZ6 | SEZ6 Entrez, Source | seizure related 6 homolog (mouse) | 1821 | 0.130 | -0.0477 | No |
| 6 | PCSK1 | PCSK1 Entrez, Source | proprotein convertase subtilisin/kexin type 1 | 1853 | 0.129 | -0.0396 | No |
| 7 | DMD | DMD Entrez, Source | dystrophin (muscular dystrophy, Duchenne and Becker types) | 2146 | 0.116 | -0.0523 | No |
| 8 | SLC6A4 | SLC6A4 Entrez, Source | solute carrier family 6 (neurotransmitter transporter, serotonin), member 4 | 2317 | 0.110 | -0.0562 | No |
| 9 | SLC9A5 | SLC9A5 Entrez, Source | solute carrier family 9 (sodium/hydrogen exchanger), member 5 | 2614 | 0.099 | -0.0706 | No |
| 10 | USP52 | USP52 Entrez, Source | ubiquitin specific peptidase 52 | 2621 | 0.098 | -0.0631 | No |
| 11 | ATRX | ATRX Entrez, Source | alpha thalassemia/mental retardation syndrome X-linked (RAD54 homolog, S. cerevisiae) | 2846 | 0.090 | -0.0727 | No |
| 12 | LHX5 | LHX5 Entrez, Source | LIM homeobox 5 | 2927 | 0.087 | -0.0717 | No |
| 13 | CTDSP1 | CTDSP1 Entrez, Source | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1 | 3001 | 0.085 | -0.0704 | No |
| 14 | UNG | UNG Entrez, Source | uracil-DNA glycosylase | 3194 | 0.079 | -0.0785 | No |
| 15 | CORT | CORT Entrez, Source | cortistatin | 3589 | 0.069 | -0.1027 | No |
| 16 | KCNA6 | KCNA6 Entrez, Source | potassium voltage-gated channel, shaker-related subfamily, member 6 | 3661 | 0.067 | -0.1026 | No |
| 17 | DPYSL2 | DPYSL2 Entrez, Source | dihydropyrimidinase-like 2 | 4035 | 0.059 | -0.1260 | No |
| 18 | GRIA4 | GRIA4 Entrez, Source | glutamate receptor, ionotrophic, AMPA 4 | 4512 | 0.048 | -0.1580 | No |
| 19 | POLD3 | POLD3 Entrez, Source | polymerase (DNA-directed), delta 3, accessory subunit | 4626 | 0.046 | -0.1628 | No |
| 20 | SP3 | SP3 Entrez, Source | Sp3 transcription factor | 4669 | 0.045 | -0.1624 | No |
| 21 | CDC25A | CDC25A Entrez, Source | cell division cycle 25A | 4801 | 0.042 | -0.1689 | No |
| 22 | MAPT | MAPT Entrez, Source | microtubule-associated protein tau | 4812 | 0.042 | -0.1663 | No |
| 23 | GABRB3 | GABRB3 Entrez, Source | gamma-aminobutyric acid (GABA) A receptor, beta 3 | 4900 | 0.040 | -0.1696 | No |
| 24 | MXD3 | MXD3 Entrez, Source | MAX dimerization protein 3 | 4925 | 0.039 | -0.1682 | No |
| 25 | KBTBD7 | KBTBD7 Entrez, Source | kelch repeat and BTB (POZ) domain containing 7 | 5504 | 0.028 | -0.2096 | No |
| 26 | SFRS2 | SFRS2 Entrez, Source | splicing factor, arginine/serine-rich 2 | 5597 | 0.026 | -0.2145 | No |
| 27 | NRP2 | NRP2 Entrez, Source | neuropilin 2 | 6135 | 0.016 | -0.2538 | No |
| 28 | HMGN2 | HMGN2 Entrez, Source | high-mobility group nucleosomal binding domain 2 | 6264 | 0.013 | -0.2624 | No |
| 29 | UGCGL1 | UGCGL1 Entrez, Source | UDP-glucose ceramide glucosyltransferase-like 1 | 6411 | 0.009 | -0.2727 | No |
| 30 | PAQR4 | PAQR4 Entrez, Source | progestin and adipoQ receptor family member IV | 6650 | 0.005 | -0.2902 | No |
| 31 | ACBD6 | ACBD6 Entrez, Source | acyl-Coenzyme A binding domain containing 6 | 6961 | -0.001 | -0.3135 | No |
| 32 | KLF4 | KLF4 Entrez, Source | Kruppel-like factor 4 (gut) | 7004 | -0.002 | -0.3165 | No |
| 33 | MAPK6 | MAPK6 Entrez, Source | mitogen-activated protein kinase 6 | 7114 | -0.004 | -0.3244 | No |
| 34 | IMPDH2 | IMPDH2 Entrez, Source | IMP (inosine monophosphate) dehydrogenase 2 | 7268 | -0.008 | -0.3353 | No |
| 35 | SLC38A1 | SLC38A1 Entrez, Source | solute carrier family 38, member 1 | 7296 | -0.008 | -0.3367 | No |
| 36 | SUMO1 | SUMO1 Entrez, Source | SMT3 suppressor of mif two 3 homolog 1 (S. cerevisiae) | 7316 | -0.009 | -0.3374 | No |
| 37 | HCN3 | HCN3 Entrez, Source | hyperpolarization activated cyclic nucleotide-gated potassium channel 3 | 7586 | -0.014 | -0.3566 | No |
| 38 | RAB11B | RAB11B Entrez, Source | RAB11B, member RAS oncogene family | 8077 | -0.025 | -0.3915 | No |
| 39 | SFRS7 | SFRS7 Entrez, Source | splicing factor, arginine/serine-rich 7, 35kDa | 8464 | -0.033 | -0.4180 | No |
| 40 | H2AFZ | H2AFZ Entrez, Source | H2A histone family, member Z | 8540 | -0.035 | -0.4208 | No |
| 41 | POU4F1 | POU4F1 Entrez, Source | POU domain, class 4, transcription factor 1 | 8602 | -0.037 | -0.4224 | No |
| 42 | PPP1CC | PPP1CC Entrez, Source | protein phosphatase 1, catalytic subunit, gamma isoform | 8785 | -0.040 | -0.4328 | No |
| 43 | NASP | NASP Entrez, Source | nuclear autoantigenic sperm protein (histone-binding) | 8949 | -0.045 | -0.4415 | No |
| 44 | PIM1 | PIM1 Entrez, Source | pim-1 oncogene | 9075 | -0.048 | -0.4471 | No |
| 45 | NCL | NCL Entrez, Source | nucleolin | 9096 | -0.049 | -0.4446 | No |
| 46 | NOLC1 | NOLC1 Entrez, Source | nucleolar and coiled-body phosphoprotein 1 | 9128 | -0.050 | -0.4430 | No |
| 47 | PVRL1 | PVRL1 Entrez, Source | poliovirus receptor-related 1 (herpesvirus entry mediator C; nectin) | 9133 | -0.050 | -0.4393 | No |
| 48 | FMO4 | FMO4 Entrez, Source | flavin containing monooxygenase 4 | 9231 | -0.052 | -0.4424 | No |
| 49 | POLA2 | POLA2 Entrez, Source | polymerase (DNA directed), alpha 2 (70kD subunit) | 9233 | -0.052 | -0.4382 | No |
| 50 | HOXC10 | HOXC10 Entrez, Source | homeobox C10 | 9351 | -0.056 | -0.4425 | No |
| 51 | KPNB1 | KPNB1 Entrez, Source | karyopherin (importin) beta 1 | 9435 | -0.058 | -0.4441 | No |
| 52 | GSPT1 | GSPT1 Entrez, Source | G1 to S phase transition 1 | 9560 | -0.061 | -0.4485 | No |
| 53 | RBBP7 | RBBP7 Entrez, Source | retinoblastoma binding protein 7 | 9796 | -0.068 | -0.4607 | No |
| 54 | CLTA | CLTA Entrez, Source | clathrin, light chain (Lca) | 9819 | -0.069 | -0.4568 | No |
| 55 | NPR3 | NPR3 Entrez, Source | natriuretic peptide receptor C/guanylate cyclase C (atrionatriuretic peptide receptor C) | 10036 | -0.076 | -0.4670 | Yes |
| 56 | PAX6 | PAX6 Entrez, Source | paired box gene 6 (aniridia, keratitis) | 10052 | -0.076 | -0.4620 | Yes |
| 57 | CTCF | CTCF Entrez, Source | CCCTC-binding factor (zinc finger protein) | 10143 | -0.079 | -0.4623 | Yes |
| 58 | ING3 | ING3 Entrez, Source | inhibitor of growth family, member 3 | 10287 | -0.084 | -0.4663 | Yes |
| 59 | PRPS1 | PRPS1 Entrez, Source | phosphoribosyl pyrophosphate synthetase 1 | 10317 | -0.085 | -0.4616 | Yes |
| 60 | XTP3TPA | XTP3TPA Entrez, Source | - | 10388 | -0.088 | -0.4598 | Yes |
| 61 | EIF4A1 | EIF4A1 Entrez, Source | eukaryotic translation initiation factor 4A, isoform 1 | 10424 | -0.089 | -0.4552 | Yes |
| 62 | TYRO3 | TYRO3 Entrez, Source | TYRO3 protein tyrosine kinase | 10473 | -0.091 | -0.4515 | Yes |
| 63 | DNMT1 | DNMT1 Entrez, Source | DNA (cytosine-5-)-methyltransferase 1 | 10538 | -0.093 | -0.4488 | Yes |
| 64 | PCNA | PCNA Entrez, Source | proliferating cell nuclear antigen | 10651 | -0.097 | -0.4494 | Yes |
| 65 | RET | RET Entrez, Source | ret proto-oncogene (multiple endocrine neoplasia and medullary thyroid carcinoma 1, Hirschsprung disease) | 10708 | -0.099 | -0.4456 | Yes |
| 66 | RHD | RHD Entrez, Source | Rh blood group, D antigen | 10757 | -0.101 | -0.4411 | Yes |
| 67 | RFC1 | RFC1 Entrez, Source | replication factor C (activator 1) 1, 145kDa | 10774 | -0.102 | -0.4340 | Yes |
| 68 | CDCA7 | CDCA7 Entrez, Source | cell division cycle associated 7 | 11253 | -0.124 | -0.4601 | Yes |
| 69 | HNRPR | HNRPR Entrez, Source | heterogeneous nuclear ribonucleoprotein R | 11314 | -0.127 | -0.4543 | Yes |
| 70 | NUP62 | NUP62 Entrez, Source | nucleoporin 62kDa | 11369 | -0.129 | -0.4479 | Yes |
| 71 | DCK | DCK Entrez, Source | deoxycytidine kinase | 11406 | -0.131 | -0.4400 | Yes |
| 72 | ILF3 | ILF3 Entrez, Source | interleukin enhancer binding factor 3, 90kDa | 11444 | -0.134 | -0.4319 | Yes |
| 73 | TLE3 | TLE3 Entrez, Source | transducin-like enhancer of split 3 (E(sp1) homolog, Drosophila) | 11492 | -0.137 | -0.4244 | Yes |
| 74 | MYH10 | MYH10 Entrez, Source | myosin, heavy chain 10, non-muscle | 11608 | -0.144 | -0.4214 | Yes |
| 75 | POLD1 | POLD1 Entrez, Source | polymerase (DNA directed), delta 1, catalytic subunit 125kDa | 11672 | -0.148 | -0.4142 | Yes |
| 76 | E2F1 | E2F1 Entrez, Source | E2F transcription factor 1 | 11673 | -0.148 | -0.4022 | Yes |
| 77 | HNRPA1 | HNRPA1 Entrez, Source | heterogeneous nuclear ribonucleoprotein A1 | 11811 | -0.158 | -0.3998 | Yes |
| 78 | ONECUT1 | ONECUT1 Entrez, Source | one cut domain, family member 1 | 12048 | -0.177 | -0.4033 | Yes |
| 79 | SMAD6 | SMAD6 Entrez, Source | SMAD, mothers against DPP homolog 6 (Drosophila) | 12050 | -0.177 | -0.3890 | Yes |
| 80 | PPIG | PPIG Entrez, Source | peptidylprolyl isomerase G (cyclophilin G) | 12293 | -0.204 | -0.3908 | Yes |
| 81 | MSH2 | MSH2 Entrez, Source | mutS homolog 2, colon cancer, nonpolyposis type 1 (E. coli) | 12401 | -0.215 | -0.3815 | Yes |
| 82 | TMPO | TMPO Entrez, Source | thymopoietin | 12402 | -0.215 | -0.3641 | Yes |
| 83 | EPHB1 | EPHB1 Entrez, Source | EPH receptor B1 | 12545 | -0.235 | -0.3558 | Yes |
| 84 | HNRPD | HNRPD Entrez, Source | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) | 12695 | -0.263 | -0.3458 | Yes |
| 85 | LIG1 | LIG1 Entrez, Source | ligase I, DNA, ATP-dependent | 12767 | -0.278 | -0.3287 | Yes |
| 86 | WEE1 | WEE1 Entrez, Source | WEE1 homolog (S. pombe) | 12897 | -0.319 | -0.3126 | Yes |
| 87 | SLCO3A1 | SLCO3A1 Entrez, Source | solute carrier organic anion transporter family, member 3A1 | 12964 | -0.345 | -0.2897 | Yes |
| 88 | SOAT1 | SOAT1 Entrez, Source | sterol O-acyltransferase (acyl-Coenzyme A: cholesterol acyltransferase) 1 | 12979 | -0.351 | -0.2623 | Yes |
| 89 | MCM7 | MCM7 Entrez, Source | MCM7 minichromosome maintenance deficient 7 (S. cerevisiae) | 13028 | -0.381 | -0.2352 | Yes |
| 90 | ID3 | ID3 Entrez, Source | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein | 13077 | -0.411 | -0.2055 | Yes |
| 91 | KIAA0101 | KIAA0101 Entrez, Source | KIAA0101 | 13128 | -0.448 | -0.1731 | Yes |
| 92 | MAT2A | MAT2A Entrez, Source | methionine adenosyltransferase II, alpha | 13252 | -0.684 | -0.1270 | Yes |
| 93 | STMN1 | STMN1 Entrez, Source | stathmin 1/oncoprotein 18 | 13288 | -0.823 | -0.0630 | Yes |
| 94 | MCM6 | MCM6 Entrez, Source | MCM6 minichromosome maintenance deficient 6 (MIS5 homolog, S. pombe) (S. cerevisiae) | 13289 | -0.828 | 0.0040 | Yes |
