Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | double_gel_and_single_gel_rma_expression_values_collapsed_to_symbols.class.cls #double_gel_8d_versus_single_gel_8d.class.cls #double_gel_8d_versus_single_gel_8d_repos |
| Phenotype | class.cls#double_gel_8d_versus_single_gel_8d_repos |
| Upregulated in class | single_gel_8d |
| GeneSet | V$E2F1_Q4_01 |
| Enrichment Score (ES) | -0.48189133 |
| Normalized Enrichment Score (NES) | -1.7085013 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.075439215 |
| FWER p-Value | 1.0 |
| PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|
| 1 | USP2 | USP2 Entrez, Source | ubiquitin specific peptidase 2 | 134 | 0.557 | 0.0314 | No |
| 2 | ITGA1 | ITGA1 Entrez, Source | integrin, alpha 1 | 278 | 0.416 | 0.0516 | No |
| 3 | BMP7 | BMP7 Entrez, Source | bone morphogenetic protein 7 (osteogenic protein 1) | 635 | 0.257 | 0.0439 | No |
| 4 | UXT | UXT Entrez, Source | ubiquitously-expressed transcript | 1225 | 0.169 | 0.0120 | No |
| 5 | FBXO9 | FBXO9 Entrez, Source | F-box protein 9 | 1505 | 0.149 | 0.0021 | No |
| 6 | PCSK1 | PCSK1 Entrez, Source | proprotein convertase subtilisin/kexin type 1 | 1853 | 0.129 | -0.0145 | No |
| 7 | DMD | DMD Entrez, Source | dystrophin (muscular dystrophy, Duchenne and Becker types) | 2146 | 0.116 | -0.0279 | No |
| 8 | SLC6A4 | SLC6A4 Entrez, Source | solute carrier family 6 (neurotransmitter transporter, serotonin), member 4 | 2317 | 0.110 | -0.0326 | No |
| 9 | USP52 | USP52 Entrez, Source | ubiquitin specific peptidase 52 | 2621 | 0.098 | -0.0481 | No |
| 10 | NDUFA11 | NDUFA11 Entrez, Source | NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 11, 14.7kDa | 2744 | 0.094 | -0.0503 | No |
| 11 | ATRX | ATRX Entrez, Source | alpha thalassemia/mental retardation syndrome X-linked (RAD54 homolog, S. cerevisiae) | 2846 | 0.090 | -0.0512 | No |
| 12 | CHGB | CHGB Entrez, Source | chromogranin B (secretogranin 1) | 3046 | 0.084 | -0.0600 | No |
| 13 | UNG | UNG Entrez, Source | uracil-DNA glycosylase | 3194 | 0.079 | -0.0652 | No |
| 14 | KCNA6 | KCNA6 Entrez, Source | potassium voltage-gated channel, shaker-related subfamily, member 6 | 3661 | 0.067 | -0.0954 | No |
| 15 | ATP5G2 | ATP5G2 Entrez, Source | ATP synthase, H+ transporting, mitochondrial F0 complex, subunit C2 (subunit 9) | 3731 | 0.066 | -0.0957 | No |
| 16 | MYC | MYC Entrez, Source | v-myc myelocytomatosis viral oncogene homolog (avian) | 3805 | 0.064 | -0.0965 | No |
| 17 | DPYSL2 | DPYSL2 Entrez, Source | dihydropyrimidinase-like 2 | 4035 | 0.059 | -0.1094 | No |
| 18 | DMRT1 | DMRT1 Entrez, Source | doublesex and mab-3 related transcription factor 1 | 4088 | 0.057 | -0.1090 | No |
| 19 | HTF9C | HTF9C Entrez, Source | - | 4181 | 0.055 | -0.1118 | No |
| 20 | FANCC | FANCC Entrez, Source | Fanconi anemia, complementation group C | 4494 | 0.049 | -0.1317 | No |
| 21 | CDC25A | CDC25A Entrez, Source | cell division cycle 25A | 4801 | 0.042 | -0.1517 | No |
| 22 | MXD3 | MXD3 Entrez, Source | MAX dimerization protein 3 | 4925 | 0.039 | -0.1581 | No |
| 23 | KBTBD7 | KBTBD7 Entrez, Source | kelch repeat and BTB (POZ) domain containing 7 | 5504 | 0.028 | -0.1996 | No |
| 24 | SFRS2 | SFRS2 Entrez, Source | splicing factor, arginine/serine-rich 2 | 5597 | 0.026 | -0.2046 | No |
| 25 | EGR3 | EGR3 Entrez, Source | early growth response 3 | 5611 | 0.025 | -0.2038 | No |
| 26 | DAXX | DAXX Entrez, Source | death-associated protein 6 | 6115 | 0.016 | -0.2405 | No |
| 27 | NRP2 | NRP2 Entrez, Source | neuropilin 2 | 6135 | 0.016 | -0.2408 | No |
| 28 | HMGN2 | HMGN2 Entrez, Source | high-mobility group nucleosomal binding domain 2 | 6264 | 0.013 | -0.2495 | No |
| 29 | PELO | PELO Entrez, Source | pelota homolog (Drosophila) | 6323 | 0.011 | -0.2530 | No |
| 30 | GLRA3 | GLRA3 Entrez, Source | glycine receptor, alpha 3 | 6466 | 0.008 | -0.2631 | No |
| 31 | PAQR4 | PAQR4 Entrez, Source | progestin and adipoQ receptor family member IV | 6650 | 0.005 | -0.2766 | No |
| 32 | TOP1 | TOP1 Entrez, Source | topoisomerase (DNA) I | 6869 | 0.001 | -0.2930 | No |
| 33 | ACBD6 | ACBD6 Entrez, Source | acyl-Coenzyme A binding domain containing 6 | 6961 | -0.001 | -0.2997 | No |
| 34 | NEGR1 | NEGR1 Entrez, Source | neuronal growth regulator 1 | 7019 | -0.003 | -0.3038 | No |
| 35 | IMPDH2 | IMPDH2 Entrez, Source | IMP (inosine monophosphate) dehydrogenase 2 | 7268 | -0.008 | -0.3220 | No |
| 36 | SLC38A1 | SLC38A1 Entrez, Source | solute carrier family 38, member 1 | 7296 | -0.008 | -0.3234 | No |
| 37 | RAB11B | RAB11B Entrez, Source | RAB11B, member RAS oncogene family | 8077 | -0.025 | -0.3804 | No |
| 38 | SFRS12 | SFRS12 Entrez, Source | splicing factor, arginine/serine-rich 12 | 8323 | -0.030 | -0.3966 | No |
| 39 | UFD1L | UFD1L Entrez, Source | ubiquitin fusion degradation 1 like (yeast) | 8494 | -0.034 | -0.4069 | No |
| 40 | H2AFZ | H2AFZ Entrez, Source | H2A histone family, member Z | 8540 | -0.035 | -0.4077 | No |
| 41 | KCND2 | KCND2 Entrez, Source | potassium voltage-gated channel, Shal-related subfamily, member 2 | 8883 | -0.043 | -0.4303 | No |
| 42 | NASP | NASP Entrez, Source | nuclear autoantigenic sperm protein (histone-binding) | 8949 | -0.045 | -0.4318 | No |
| 43 | PIM1 | PIM1 Entrez, Source | pim-1 oncogene | 9075 | -0.048 | -0.4377 | No |
| 44 | NCL | NCL Entrez, Source | nucleolin | 9096 | -0.049 | -0.4356 | No |
| 45 | PVRL1 | PVRL1 Entrez, Source | poliovirus receptor-related 1 (herpesvirus entry mediator C; nectin) | 9133 | -0.050 | -0.4346 | No |
| 46 | FMO4 | FMO4 Entrez, Source | flavin containing monooxygenase 4 | 9231 | -0.052 | -0.4380 | No |
| 47 | POLA2 | POLA2 Entrez, Source | polymerase (DNA directed), alpha 2 (70kD subunit) | 9233 | -0.052 | -0.4342 | No |
| 48 | USP1 | USP1 Entrez, Source | ubiquitin specific peptidase 1 | 9270 | -0.054 | -0.4330 | No |
| 49 | HOXC10 | HOXC10 Entrez, Source | homeobox C10 | 9351 | -0.056 | -0.4348 | No |
| 50 | FBXL20 | FBXL20 Entrez, Source | F-box and leucine-rich repeat protein 20 | 9357 | -0.056 | -0.4310 | No |
| 51 | KPNB1 | KPNB1 Entrez, Source | karyopherin (importin) beta 1 | 9435 | -0.058 | -0.4325 | No |
| 52 | GATA3 | GATA3 Entrez, Source | GATA binding protein 3 | 9441 | -0.058 | -0.4286 | No |
| 53 | PIK3R3 | PIK3R3 Entrez, Source | phosphoinositide-3-kinase, regulatory subunit 3 (p55, gamma) | 9602 | -0.063 | -0.4360 | No |
| 54 | PPP1R9B | PPP1R9B Entrez, Source | protein phosphatase 1, regulatory subunit 9B, spinophilin | 9861 | -0.070 | -0.4502 | No |
| 55 | CTCF | CTCF Entrez, Source | CCCTC-binding factor (zinc finger protein) | 10143 | -0.079 | -0.4655 | No |
| 56 | NR3C2 | NR3C2 Entrez, Source | nuclear receptor subfamily 3, group C, member 2 | 10284 | -0.084 | -0.4698 | No |
| 57 | ING3 | ING3 Entrez, Source | inhibitor of growth family, member 3 | 10287 | -0.084 | -0.4637 | No |
| 58 | PRPS1 | PRPS1 Entrez, Source | phosphoribosyl pyrophosphate synthetase 1 | 10317 | -0.085 | -0.4595 | No |
| 59 | NCOA6 | NCOA6 Entrez, Source | nuclear receptor coactivator 6 | 10335 | -0.086 | -0.4544 | No |
| 60 | XTP3TPA | XTP3TPA Entrez, Source | - | 10388 | -0.088 | -0.4518 | No |
| 61 | DNMT1 | DNMT1 Entrez, Source | DNA (cytosine-5-)-methyltransferase 1 | 10538 | -0.093 | -0.4561 | No |
| 62 | PCNA | PCNA Entrez, Source | proliferating cell nuclear antigen | 10651 | -0.097 | -0.4573 | No |
| 63 | RHD | RHD Entrez, Source | Rh blood group, D antigen | 10757 | -0.101 | -0.4577 | No |
| 64 | RFC1 | RFC1 Entrez, Source | replication factor C (activator 1) 1, 145kDa | 10774 | -0.102 | -0.4513 | No |
| 65 | RPS19 | RPS19 Entrez, Source | ribosomal protein S19 | 10892 | -0.106 | -0.4522 | No |
| 66 | CDCA7 | CDCA7 Entrez, Source | cell division cycle associated 7 | 11253 | -0.124 | -0.4702 | No |
| 67 | NUP153 | NUP153 Entrez, Source | nucleoporin 153kDa | 11280 | -0.126 | -0.4628 | No |
| 68 | DCK | DCK Entrez, Source | deoxycytidine kinase | 11406 | -0.131 | -0.4624 | No |
| 69 | RALY | RALY Entrez, Source | RNA binding protein, autoantigenic (hnRNP-associated with lethal yellow homolog (mouse)) | 11665 | -0.148 | -0.4709 | Yes |
| 70 | E2F1 | E2F1 Entrez, Source | E2F transcription factor 1 | 11673 | -0.148 | -0.4604 | Yes |
| 71 | KLF5 | KLF5 Entrez, Source | Kruppel-like factor 5 (intestinal) | 11774 | -0.155 | -0.4564 | Yes |
| 72 | HNRPA1 | HNRPA1 Entrez, Source | heterogeneous nuclear ribonucleoprotein A1 | 11811 | -0.158 | -0.4474 | Yes |
| 73 | DDX17 | DDX17 Entrez, Source | DEAD (Asp-Glu-Ala-Asp) box polypeptide 17 | 11914 | -0.167 | -0.4426 | Yes |
| 74 | HMGA1 | HMGA1 Entrez, Source | high mobility group AT-hook 1 | 12047 | -0.177 | -0.4394 | Yes |
| 75 | SMAD6 | SMAD6 Entrez, Source | SMAD, mothers against DPP homolog 6 (Drosophila) | 12050 | -0.177 | -0.4263 | Yes |
| 76 | TLE4 | TLE4 Entrez, Source | transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila) | 12093 | -0.181 | -0.4160 | Yes |
| 77 | YWHAQ | YWHAQ Entrez, Source | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide | 12130 | -0.184 | -0.4050 | Yes |
| 78 | NUMA1 | NUMA1 Entrez, Source | nuclear mitotic apparatus protein 1 | 12531 | -0.233 | -0.4179 | Yes |
| 79 | EPHB1 | EPHB1 Entrez, Source | EPH receptor B1 | 12545 | -0.235 | -0.4013 | Yes |
| 80 | NUP155 | NUP155 Entrez, Source | nucleoporin 155kDa | 12674 | -0.259 | -0.3917 | Yes |
| 81 | HNRPD | HNRPD Entrez, Source | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) | 12695 | -0.263 | -0.3736 | Yes |
| 82 | WEE1 | WEE1 Entrez, Source | WEE1 homolog (S. pombe) | 12897 | -0.319 | -0.3650 | Yes |
| 83 | DHX40 | DHX40 Entrez, Source | DEAH (Asp-Glu-Ala-His) box polypeptide 40 | 13019 | -0.376 | -0.3462 | Yes |
| 84 | MCM7 | MCM7 Entrez, Source | MCM7 minichromosome maintenance deficient 7 (S. cerevisiae) | 13028 | -0.381 | -0.3184 | Yes |
| 85 | UCHL1 | UCHL1 Entrez, Source | ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) | 13032 | -0.382 | -0.2902 | Yes |
| 86 | ID3 | ID3 Entrez, Source | inhibitor of DNA binding 3, dominant negative helix-loop-helix protein | 13077 | -0.411 | -0.2629 | Yes |
| 87 | PTMA | PTMA Entrez, Source | prothymosin, alpha (gene sequence 28) | 13120 | -0.443 | -0.2331 | Yes |
| 88 | KIAA0101 | KIAA0101 Entrez, Source | KIAA0101 | 13128 | -0.448 | -0.2002 | Yes |
| 89 | CASP2 | CASP2 Entrez, Source | caspase 2, apoptosis-related cysteine peptidase (neural precursor cell expressed, developmentally down-regulated 2) | 13202 | -0.565 | -0.1637 | Yes |
| 90 | MAT2A | MAT2A Entrez, Source | methionine adenosyltransferase II, alpha | 13252 | -0.684 | -0.1164 | Yes |
| 91 | STMN1 | STMN1 Entrez, Source | stathmin 1/oncoprotein 18 | 13288 | -0.823 | -0.0577 | Yes |
| 92 | MCM6 | MCM6 Entrez, Source | MCM6 minichromosome maintenance deficient 6 (MIS5 homolog, S. pombe) (S. cerevisiae) | 13289 | -0.828 | 0.0040 | Yes |
